PT90717A - Processo de preparacao de 3,4,5,6-tetra-hidrofuro {4,3,2,ef}{3}benzazepinas substituidas e de composicoes farmaceuticas que as contem - Google Patents

Processo de preparacao de 3,4,5,6-tetra-hidrofuro {4,3,2,ef}{3}benzazepinas substituidas e de composicoes farmaceuticas que as contem

Info

Publication number
PT90717A
PT90717A PT90717A PT9071789A PT90717A PT 90717 A PT90717 A PT 90717A PT 90717 A PT90717 A PT 90717A PT 9071789 A PT9071789 A PT 9071789A PT 90717 A PT90717 A PT 90717A
Authority
PT
Portugal
Prior art keywords
pharmaceutical compositions
tetrahydrofur
preparation process
compositions containing
substituted benzazepines
Prior art date
Application number
PT90717A
Other languages
English (en)
Other versions
PT90717B (pt
Inventor
John Joseph Lafferty
Robert Michael Demarinis
Joseph Walter Venslavsky
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of PT90717A publication Critical patent/PT90717A/pt
Publication of PT90717B publication Critical patent/PT90717B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
PT90717A 1988-06-01 1989-06-01 Processo de preparacao de 3,4,5,6-tetra-hidrofuro {4,3,2,ef}{3}benzazepinas substituidas e de composicoes farmaceuticas que as contem PT90717B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20081688A 1988-06-01 1988-06-01

Publications (2)

Publication Number Publication Date
PT90717A true PT90717A (pt) 1989-12-29
PT90717B PT90717B (pt) 1994-11-30

Family

ID=22743334

Family Applications (1)

Application Number Title Priority Date Filing Date
PT90717A PT90717B (pt) 1988-06-01 1989-06-01 Processo de preparacao de 3,4,5,6-tetra-hidrofuro {4,3,2,ef}{3}benzazepinas substituidas e de composicoes farmaceuticas que as contem

Country Status (13)

Country Link
EP (1) EP0344982B1 (pt)
JP (1) JPH03504606A (pt)
KR (1) KR900701788A (pt)
CN (1) CN1038099A (pt)
AT (1) ATE114310T1 (pt)
AU (1) AU630100B2 (pt)
CA (1) CA1320485C (pt)
DE (1) DE68919438T2 (pt)
NZ (1) NZ229296A (pt)
PT (1) PT90717B (pt)
WO (1) WO1989012051A1 (pt)
ZA (1) ZA894096B (pt)
ZW (1) ZW6889A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1320486C (en) * 1988-06-01 1993-07-20 John J. Lafferty .alpha. -adrenergic receptor antagonists
CN100391460C (zh) * 2002-06-20 2008-06-04 诺瓦乐医药公司 α-肾上腺素能受体拮抗剂的稳定配方及其用途
US9556200B2 (en) 2012-03-06 2017-01-31 Takeda Pharmaceutical Company Limited Tricyclic compound

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795451A (fr) * 1972-02-23 1973-08-16 Pfizer Agents hypoglycemiants aza indoliques tricycliques
US3950343A (en) * 1973-11-06 1976-04-13 Ayerst, Mckenna And Harrison Ltd. Pyrroloisoquinoline derivatives
EP0139584B1 (fr) * 1983-10-17 1988-05-18 Synthelabo Dérivés d'imidazoline, leur préparation et leur application en thérapeutique
DE3525564A1 (de) * 1985-07-15 1987-02-05 Schering Ag Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
CA1320486C (en) * 1988-06-01 1993-07-20 John J. Lafferty .alpha. -adrenergic receptor antagonists

Also Published As

Publication number Publication date
CA1320485C (en) 1993-07-20
EP0344982A2 (en) 1989-12-06
ZA894096B (en) 1990-06-27
EP0344982A3 (en) 1991-05-15
ATE114310T1 (de) 1994-12-15
WO1989012051A1 (en) 1989-12-14
PT90717B (pt) 1994-11-30
EP0344982B1 (en) 1994-11-23
CN1038099A (zh) 1989-12-20
JPH03504606A (ja) 1991-10-09
AU630100B2 (en) 1992-10-22
DE68919438T2 (de) 1995-05-04
ZW6889A1 (en) 1989-08-30
DE68919438D1 (de) 1995-01-05
KR900701788A (ko) 1990-12-04
AU3770889A (en) 1990-01-05
NZ229296A (en) 1991-05-28

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19940516

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19961130