PT92603A - Processo de producao de factor de crescimento transformante, quimerico,beta - Google Patents

Processo de producao de factor de crescimento transformante, quimerico,beta

Info

Publication number: PT92603A
Authority: PT; Portugal
Prior art keywords: beta; production; growth factor; quimerico; transformante
Prior art date: 1988-12-15

Application number

PT92603A

Other languages

English (en)

Other versions

PT92603B (pt

Inventor

Anthony F Purchio

Linda Madisen

Original Assignee

Oncogen

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-15

Filing date

1989-12-15

Publication date

1990-06-29

1989-12-15 Application filed by Oncogen filed Critical Oncogen

1990-06-29 Publication of PT92603A publication Critical patent/PT92603A/pt

1995-09-12 Publication of PT92603B publication Critical patent/PT92603B/pt

Links

239000003102 growth factor Substances 0.000 title 1
108020004511 Recombinant DNA Proteins 0.000 abstract 1
102000046299 Transforming Growth Factor beta1 Human genes 0.000 abstract 1
102000011117 Transforming Growth Factor beta2 Human genes 0.000 abstract 1
101800002279 Transforming growth factor beta-1 Proteins 0.000 abstract 1
101800000304 Transforming growth factor beta-2 Proteins 0.000 abstract 1
125000003275 alpha amino acid group Chemical group 0.000 abstract 1
125000000539 amino acid group Chemical group 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
229940099456 transforming growth factor beta 1 Drugs 0.000 abstract 1
229940072041 transforming growth factor beta 2 Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Chemistry (AREA)
Toxicology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Jellies, Jams, And Syrups (AREA)

PT92603A 1988-12-15 1989-12-15 Processo de producao de factor de crescimento transformante, quimerico,beta PT92603B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US28497288A	1988-12-15	1988-12-15

Publications (2)

Publication Number	Publication Date
PT92603A true PT92603A (pt)	1990-06-29
PT92603B PT92603B (pt)	1995-09-12

Family

ID=23092228

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT92603A PT92603B (pt)	1988-12-15	1989-12-15	Processo de producao de factor de crescimento transformante, quimerico,beta

Country Status (18)

Country	Link
US (1)	US5244793A (pt)
EP (1)	EP0374044B1 (pt)
JP (1)	JPH0335794A (pt)
KR (1)	KR900009983A (pt)
CN (1)	CN1045994A (pt)
AT (1)	ATE111520T1 (pt)
AU (1)	AU634733B2 (pt)
CA (1)	CA2005120A1 (pt)
DE (1)	DE68918248T2 (pt)
DK (1)	DK633389A (pt)
ES (1)	ES2063834T3 (pt)
FI (1)	FI97299C (pt)
HU (1)	HUT52550A (pt)
IE (1)	IE66571B1 (pt)
IL (1)	IL92669A (pt)
NO (1)	NO300464B1 (pt)
PT (1)	PT92603B (pt)
ZA (1)	ZA899517B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5304541A (en) *	1988-12-15	1994-04-19	Bristol-Myers Squibb Company	Methods using novel chimeric transforming growth factor-β1/β2
CA2003886A1 (en) *	1988-12-16	1990-06-16	Anthony F. Purchio	Cloning and expression of simian transforming growth factor-beta 1
US5169764A (en) *	1990-08-08	1992-12-08	Regeneron Pharmaceuticals, Inc.	Multitrophic and multifunctional chimeric neurotrophic factors, and nucleic acids and plasmids encoding the chimeras
US5206023A (en) *	1991-01-31	1993-04-27	Robert F. Shaw	Method and compositions for the treatment and repair of defects or lesions in cartilage
GB9106678D0 (en) *	1991-03-28	1991-05-15	Ferguson Mark W J	Wound healing
US5270300A (en) *	1991-09-06	1993-12-14	Robert Francis Shaw	Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone
US5811447A (en)	1993-01-28	1998-09-22	Neorx Corporation	Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en)	1991-09-27	2003-02-04	Neorx Corporation	Therapeutic inhibitor of vascular smooth muscle cells
AU2738392A (en) *	1991-11-11	1993-05-13	Ciba-Geigy Ag	Novel hybrid transforming growth factors
IT1259042B (it) *	1992-01-27	1996-03-11	Mini Ricerca Scient Tecnolog	Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante
US6395494B1 (en)	1993-05-13	2002-05-28	Neorx Corporation	Method to determine TGF-β
US5420243A (en) *	1993-01-26	1995-05-30	Celtrix Pharmaceuticals, Inc.	Biologically active TGF-β2 peptides
US6663881B2 (en)	1993-01-28	2003-12-16	Neorx Corporation	Therapeutic inhibitor of vascular smooth muscle cells
US6491938B2 (en)	1993-05-13	2002-12-10	Neorx Corporation	Therapeutic inhibitor of vascular smooth muscle cells
US5981568A (en)	1993-01-28	1999-11-09	Neorx Corporation	Therapeutic inhibitor of vascular smooth muscle cells
WO1994026303A1 (en) *	1993-05-13	1994-11-24	Neorx Corporation	Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells
WO1998046588A2 (en)	1997-04-11	1998-10-22	Neorx Corporation	Compounds and therapies for the prevention of vascular and non-vascular pathologies
US6613083B2 (en)	2001-05-02	2003-09-02	Eckhard Alt	Stent device and method
KR100688871B1 (ko) *	2002-03-12	2007-03-02	티슈진, 인코포레이티드	연골세포 및 ＴＧＦ-β를 사용한 연골 재생

1989
- 1989-12-11 CA CA002005120A patent/CA2005120A1/en not_active Abandoned
- 1989-12-12 FI FI895935A patent/FI97299C/fi not_active IP Right Cessation
- 1989-12-13 ZA ZA899517A patent/ZA899517B/xx unknown
- 1989-12-13 IE IE398489A patent/IE66571B1/en not_active IP Right Cessation
- 1989-12-13 ES ES89403463T patent/ES2063834T3/es not_active Expired - Lifetime
- 1989-12-13 DE DE68918248T patent/DE68918248T2/de not_active Expired - Fee Related
- 1989-12-13 EP EP89403463A patent/EP0374044B1/en not_active Expired - Lifetime
- 1989-12-13 AT AT89403463T patent/ATE111520T1/de not_active IP Right Cessation
- 1989-12-13 IL IL9266989A patent/IL92669A/xx not_active IP Right Cessation
- 1989-12-14 NO NO895028A patent/NO300464B1/no unknown
- 1989-12-14 HU HU896613A patent/HUT52550A/hu unknown
- 1989-12-14 DK DK633389A patent/DK633389A/da not_active Application Discontinuation
- 1989-12-15 AU AU46834/89A patent/AU634733B2/en not_active Ceased
- 1989-12-15 KR KR1019890018784A patent/KR900009983A/ko not_active Withdrawn
- 1989-12-15 JP JP1325735A patent/JPH0335794A/ja active Pending
- 1989-12-15 PT PT92603A patent/PT92603B/pt not_active IP Right Cessation
- 1989-12-15 CN CN89109355A patent/CN1045994A/zh active Pending
1991
- 1991-03-08 US US07/667,246 patent/US5244793A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ATE111520T1 (de)	1994-09-15
DE68918248D1 (de)	1994-10-20
FI97299C (fi)	1996-11-25
ZA899517B (en)	1990-09-26
EP0374044A2 (en)	1990-06-20
EP0374044A3 (en)	1991-07-31
NO895028D0 (no)	1989-12-14
HUT52550A (en)	1990-07-28
NO300464B1 (no)	1997-06-02
IE893984L (en)	1990-06-15
IL92669A (en)	1997-02-18
DK633389A (da)	1990-06-16
ES2063834T3 (es)	1995-01-16
US5244793A (en)	1993-09-14
AU4683489A (en)	1990-06-21
KR900009983A (ko)	1990-07-06
DE68918248T2 (de)	1995-05-04
FI97299B (fi)	1996-08-15
NO895028L (no)	1990-06-18
CN1045994A (zh)	1990-10-10
AU634733B2 (en)	1993-03-04
FI895935A0 (fi)	1989-12-12
IL92669A0 (en)	1990-08-31
HU896613D0 (en)	1990-02-28
DK633389D0 (da)	1989-12-14
IE66571B1 (en)	1996-01-24
PT92603B (pt)	1995-09-12
EP0374044B1 (en)	1994-09-14
CA2005120A1 (en)	1990-06-15
JPH0335794A (ja)	1991-02-15

Legal Events

Date

Code

Title

Description

1995-09-12

FG3A

Patent granted, date of granting

Effective date: 19950502

2000-03-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19991130

Publication	Publication Date	Title
FI97299C (fi)	1996-11-25	Menetelmä kimeerisen transformoivan beta-kasvutekijän valmistamiseksi
DE68929510D1 (de)	2004-02-12	Nukleotidsequenzen, die für ein Protein mit Ureaseaktivität kodieren
ATE203270T1 (de)	2001-08-15	Verfahren für die herstellung von proteinen
EP0174367A4 (en)	1988-08-29	HOSTS AND METHODS FOR PRODUCING RECOMBINANT PRODUCTS IN LARGE QUANTITIES.
HUT43630A (en)	1987-11-30	Mammalian interleukine-4 and process for producing it
PT92278A (pt)	1990-05-31	Processo para a preparacao de proteinas de ligacao de factor de crescimento semelhante a insulina
DE3586773D1 (de)	1992-11-26	Verfahren zur beseitigung von n-endaminosaeureresten aus eukaryotpolypeptidanlagen und so erzeugte polypeptide.
ATE90944T1 (de)	1993-07-15	Fuer ein hirudinaehnliches protein kodierende dns- sequenz und verfahren zur herstellung eines solchen proteins.
DE68919246D1 (de)	1994-12-15	Verfahren zur Herstellung von Aminosäuren.
GR3027671T3 (en)	1998-11-30	Protein with bone formation ability and process for its production
HUT45564A (en)	1988-07-28	Process for producing hirudine variants
FI890127A0 (fi)	1989-01-11	Menetelmä terapeuttisesti käyttökelpoisen hirudiinijohdannaisen valmistamiseksi
EP0317627A4 (en)	1990-12-12	Oncogene-encoded polypeptide having growth factor activity and methods of production and use thereof
DE59409964D1 (de)	2002-01-03	Rekombinante D-Hydantoinase, Verfahren zur Herstellung und Verwendung
ATE113986T1 (de)	1994-11-15	Verfahren zur herstellung von aprotinin und aprotinin-homologen in hefe.
DE3781832D1 (de)	1992-10-29	C-terminal-alpha-amidierendes enzym und verfahren zu dessen herstellung und verwendung.
DK0828004T3 (da)	2007-03-19	Proteindisulfidisomerase-gen afledt af stamme af methylotrof gær
ATE145939T1 (de)	1996-12-15	Mitogen für die glatte muskulatur und dessen kodierende dns
GR3001086T3 (en)	1992-04-17	Substituted dioxanones, method for preparing same and use thereof
SE8403929D0 (sv)	1984-07-31	Recombinant dna molecule, transformed microorganisms and process for producing penicillin v amidase
DK210288A (da)	1988-04-18	Overproduktion af exocelllulaere proteiner