PT92668A - Processo para a preparacao de derivados de azabiciclo-heptano - Google Patents

Processo para a preparacao de derivados de azabiciclo-heptano

Info

Publication number: PT92668A
Authority: PT; Portugal
Prior art keywords: azabicyclo; preparation; heptane derivatives; heptane; derivatives
Prior art date: 1988-12-23

Application number

PT92668A

Other languages

English (en)

Other versions

PT92668B (pt

Inventor

Michael Stewart Hadley

Paul Adrian Wyman

Barry Sidney Orlek

Original Assignee

Beecham Group Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-23

Filing date

1989-12-21

Publication date

1990-06-29

1989-12-21 Application filed by Beecham Group Plc filed Critical Beecham Group Plc

1990-06-29 Publication of PT92668A publication Critical patent/PT92668A/pt

1995-09-12 Publication of PT92668B publication Critical patent/PT92668B/pt

Links

UUAVYXKRUSVCDJ-UHFFFAOYSA-N 1-cycloheptylazepane Chemical class C1CCCCCC1N1CCCCCC1 UUAVYXKRUSVCDJ-UHFFFAOYSA-N 0.000 title 1
206010012289 Dementia Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Photoreceptors In Electrophotography (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Mechanical Treatment Of Semiconductor (AREA)

PT92668A 1988-12-23 1989-12-21 Processo para a preparacao de derivados de azabiciclo-heptano PT92668B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB888830226A GB8830226D0 (en)	1988-12-23	1988-12-23	Novel compounds

Publications (2)

Publication Number	Publication Date
PT92668A true PT92668A (pt)	1990-06-29
PT92668B PT92668B (pt)	1995-09-12

Family

ID=10649157

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT92668A PT92668B (pt)	1988-12-23	1989-12-21	Processo para a preparacao de derivados de azabiciclo-heptano

Country Status (13)

Country	Link
US (1)	US5043342A (pt)
EP (1)	EP0375450B1 (pt)
JP (1)	JPH02215782A (pt)
KR (1)	KR900009638A (pt)
AT (1)	ATE122352T1 (pt)
AU (1)	AU620957B2 (pt)
CA (1)	CA2006436A1 (pt)
DE (1)	DE68922596T2 (pt)
DK (1)	DK656889A (pt)
GB (1)	GB8830226D0 (pt)
NZ (1)	NZ231970A (pt)
PT (1)	PT92668B (pt)
ZA (1)	ZA899821B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69026197T2 (de) *	1989-10-07	1997-01-09	Beecham Group Plc	Azabizyklische Verbindungen, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
GB9507203D0 (en) *	1995-04-07	1995-05-31	Smithkline Beecham Plc	Novel compounds
KR100441404B1 (ko) *	2002-01-24	2004-07-23	한국과학기술연구원	신규한 알케닐 아자 두 고리 화합물 및 그 제조방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2658067A (en) *		1953-11-03		Substituted carbamic acdj esters
GB1053085A (pt) *	1964-03-26
US3501471A (en) *	1966-09-21	1970-03-17	American Cyanamid Co	Novel 2,3-heterocyclic fused quinuclidines,and 3-substituted quinuclidine-2-carboxylate derivatives
US3681363A (en) *	1970-08-20	1972-08-01	Univ Temple	Spiro(imidazolidine-4,3{40 -quinuclidine)-2,5-diones
US4038402A (en) *	1974-03-05	1977-07-26	Mikhail Emmanuilovich Kaminka	Method of effecting antihistaminic, antiserotonin and antiallergic actions
US3917615A (en) *	1974-04-01	1975-11-04	Searle & Co	1,1-Diaryl-1-oxadiazol-alkylamines
US4203990A (en) *	1979-04-30	1980-05-20	G. D. Searle & Co.	Anti-diarrheal 2-substituted quinuclidines
GB8314391D0 (en) *	1983-05-24	1983-06-29	Kefalas As	Heterocyclic compounds
JPS6191185A (ja) *	1984-10-11	1986-05-09	Sumitomo Seiyaku Kk	新規なオキサジアゾリル−１，４−ジヒドロピリジン誘導体
US4599344A (en) *	1984-10-31	1986-07-08	Schering A.G.	Quinuclidines and quinuclidinium salts as antiarrhythmic agents
NZ219646A (en) *	1986-03-27	1990-10-26	Merck Sharp & Dohme	Oxadiazole derivatives of azacyclics for treating cns disorders
DE3789039T2 (de) *	1986-06-27	1994-06-09	Beecham Group Plc	Verbrückte bicyclische N-heterocyclische Verbindungen.
NZ225999A (en) *	1987-09-10	1992-04-28	Merck Sharp & Dohme	Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
EP0307141B1 (en) *	1987-09-10	1993-01-13	MERCK SHARP & DOHME LTD.	Oxazoles and thiazoles for the treatment of senile dementia
IL88156A (en) *	1987-11-13	1997-02-18	Novo Nordisk As	Azacyclic compounds their preparation and pharmaceutical compositions containing them

1988
- 1988-12-23 GB GB888830226A patent/GB8830226D0/en active Pending
1989
- 1989-12-21 DE DE68922596T patent/DE68922596T2/de not_active Expired - Fee Related
- 1989-12-21 DK DK656889A patent/DK656889A/da not_active Application Discontinuation
- 1989-12-21 US US07/454,170 patent/US5043342A/en not_active Expired - Fee Related
- 1989-12-21 AT AT89313491T patent/ATE122352T1/de not_active IP Right Cessation
- 1989-12-21 EP EP89313491A patent/EP0375450B1/en not_active Expired - Lifetime
- 1989-12-21 ZA ZA899821A patent/ZA899821B/xx unknown
- 1989-12-21 CA CA002006436A patent/CA2006436A1/en not_active Abandoned
- 1989-12-21 PT PT92668A patent/PT92668B/pt not_active IP Right Cessation
- 1989-12-21 NZ NZ231970A patent/NZ231970A/en unknown
- 1989-12-22 KR KR1019890019276A patent/KR900009638A/ko not_active Withdrawn
- 1989-12-22 JP JP1331496A patent/JPH02215782A/ja active Pending
- 1989-12-22 AU AU47064/89A patent/AU620957B2/en not_active Ceased

Also Published As

Publication number	Publication date
ATE122352T1 (de)	1995-05-15
KR900009638A (ko)	1990-07-05
PT92668B (pt)	1995-09-12
EP0375450B1 (en)	1995-05-10
ZA899821B (en)	1990-12-28
DK656889A (da)	1990-06-24
EP0375450A3 (en)	1991-07-31
DK656889D0 (da)	1989-12-21
NZ231970A (en)	1992-01-29
CA2006436A1 (en)	1990-06-23
AU620957B2 (en)	1992-02-27
US5043342A (en)	1991-08-27
AU4706489A (en)	1990-06-28
DE68922596D1 (de)	1995-06-14
JPH02215782A (ja)	1990-08-28
EP0375450A2 (en)	1990-06-27
GB8830226D0 (en)	1989-02-22
DE68922596T2 (de)	1995-09-28

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Legal Events

Date

Code

Title

Description

1995-09-12

FG3A

Patent granted, date of granting

Effective date: 19950505

1997-03-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19961130