PT947504E - Derivados de vitamina d 16-eno - Google Patents

Derivados de vitamina d 16-eno

Info

Publication number
PT947504E
PT947504E PT97949173T PT97949173T PT947504E PT 947504 E PT947504 E PT 947504E PT 97949173 T PT97949173 T PT 97949173T PT 97949173 T PT97949173 T PT 97949173T PT 947504 E PT947504 E PT 947504E
Authority
PT
Portugal
Prior art keywords
vitamin
group
eno
derivatives
hydroxyl group
Prior art date
Application number
PT97949173T
Other languages
English (en)
Portuguese (pt)
Inventor
A Chugai Kawase
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of PT947504E publication Critical patent/PT947504E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/0065Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
    • C07J7/007Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT97949173T 1996-12-20 1997-12-19 Derivados de vitamina d 16-eno PT947504E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34178696 1996-12-20

Publications (1)

Publication Number Publication Date
PT947504E true PT947504E (pt) 2003-12-31

Family

ID=18348753

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97949173T PT947504E (pt) 1996-12-20 1997-12-19 Derivados de vitamina d 16-eno

Country Status (13)

Country Link
US (3) US6326503B1 (2)
EP (1) EP0947504B1 (2)
KR (2) KR20050123185A (2)
AT (1) ATE248814T1 (2)
AU (1) AU720454B2 (2)
CA (1) CA2275382A1 (2)
DE (1) DE69724646T2 (2)
DK (1) DK0947504T3 (2)
ES (1) ES2206758T3 (2)
IL (2) IL161890A0 (2)
NO (1) NO992981L (2)
PT (1) PT947504E (2)
WO (1) WO1998028266A1 (2)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010007907A1 (en) * 1997-05-16 2001-07-12 Women And Infants Hospital 3-epi compounds of vitamin d3 and uses thereof
CN1341213A (zh) * 1999-02-18 2002-03-20 中外制药株式会社 筛选具有维生素d受体亲和性的化合物的方法
US6960576B2 (en) 1999-09-13 2005-11-01 Bristol-Myers Squibb Pharma Company Hydroxyalkanoylaminolactams and related structures as inhibitors of Aβ protein production
EP1275643A4 (en) * 2000-04-19 2009-06-03 Chugai Pharmaceutical Co Ltd VITAMIN D DERIVATIVES
ES2364623T3 (es) * 2000-06-15 2011-09-08 Chugai Seiyaku Kabushiki Kaisha Derivados de vitamina d que poseen un átomo 22-oxa o 22-tia, una cadena lateral c17 sustituida con un grupo ácido, éster o amida y un enlace doble 16(17).
IL153395A0 (en) * 2000-06-15 2003-07-06 Chugai Pharmaceutical Co Ltd Vitamin d derivatives
CA2586679A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
JP4961562B2 (ja) * 2005-03-04 2012-06-27 国立大学法人 東京医科歯科大学 19−ノルビタミンd誘導体
JP5095413B2 (ja) * 2005-11-30 2012-12-12 中外製薬株式会社 光反応を用いるビタミンd誘導体の製法
EP2025667B1 (en) 2006-06-02 2016-08-10 Nippon Shinyaku Co., Ltd. 9,10-secopregnane derivative and pharmaceutical
CA2981549A1 (en) 2009-01-27 2010-08-05 Berg Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
CN106265695B (zh) 2009-08-14 2021-05-07 博格有限责任公司 用于治疗脱发的维生素d3及其类似物
WO2012151058A1 (en) 2011-05-03 2012-11-08 Wisconsin Alumni Research Foundation (20s)-24-(p-toluenesulfonyloxy)-25,26,27-trinorvitamin d3 analogs and their uses
CN112156097A (zh) 2013-05-29 2021-01-01 博格有限责任公司 使用维生素d预防或减轻化疗诱发的脱发
CN106279239B (zh) * 2015-05-29 2019-06-28 上海彩迩文生化科技有限公司 多烯化合物、制备方法及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
JPH0680626A (ja) * 1991-05-09 1994-03-22 Chugai Pharmaceut Co Ltd 新規な22−オキサビタミンd誘導体
GB9226877D0 (en) * 1992-12-23 1993-02-17 Leo Pharm Prod Ltd Chemical compounds
JP3415877B2 (ja) * 1993-03-05 2003-06-09 中外製薬株式会社 22−オキサビタミンd誘導体
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
US6121469A (en) * 1993-12-23 2000-09-19 The Regents Of The University Of California Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs
JP3759639B2 (ja) * 1994-04-11 2006-03-29 中外製薬株式会社 22−チアビタミン▲d3▼誘導体
ATE195513T1 (de) * 1994-04-11 2000-09-15 Chugai Pharmaceutical Co Ltd 22-thiavitamin-d3-derivate
PE28297A1 (es) * 1995-01-26 1997-08-20 Hoffmann La Roche Empleo dermatologico de derivados de vitamina d
JP3715673B2 (ja) * 1995-03-10 2005-11-09 中外製薬株式会社 ビタミンd合成中間体の製造方法
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs

Also Published As

Publication number Publication date
NO992981L (no) 1999-08-18
US20020193616A1 (en) 2002-12-19
ATE248814T1 (de) 2003-09-15
KR20050123185A (ko) 2005-12-29
KR100573234B1 (ko) 2006-04-24
WO1998028266A1 (en) 1998-07-02
DK0947504T3 (da) 2003-11-24
IL130484A0 (en) 2000-06-01
US20020032340A1 (en) 2002-03-14
US6326503B1 (en) 2001-12-04
IL130484A (en) 2004-07-25
DE69724646D1 (de) 2003-10-09
US6433200B1 (en) 2002-08-13
EP0947504A1 (en) 1999-10-06
KR20000057692A (ko) 2000-09-25
CA2275382A1 (en) 1998-07-02
AU720454B2 (en) 2000-06-01
EP0947504A4 (2) 1999-11-17
AU7872798A (en) 1998-07-17
IL161890A0 (en) 2005-11-20
EP0947504B1 (en) 2003-09-03
NO992981D0 (no) 1999-06-17
DE69724646T2 (de) 2004-06-17
US6555699B2 (en) 2003-04-29
ES2206758T3 (es) 2004-05-16

Similar Documents

Publication Publication Date Title
EP0731106A4 (en) Novel peptide derivative
PT947504E (pt) Derivados de vitamina d 16-eno
PT918776E (pt) Sintese total de acilfulvenos antitumorais
DK0826688T3 (da) Pentacykliske forbindelser
DE69918695D1 (de) Sauerstoffhaltige heterocyclische verbindungen
DK0784055T3 (da) Pyrimidinylpyrazolderivater
DK0958821T3 (da) Fedtemulsion, der indeholder xanthinderivat
DE69518410D1 (de) 22-thiavitamin-d3-derivate
ATE210642T1 (de) 2-substituierte vitamin-d3-derivate
ATE304004T1 (de) Verfahren zur herstellung von 2-alkyl-3- aminothiophen derivate und 3-aminothiophen derivate
DK0963998T3 (da) Azasteroidforbindelse til behandling eller prævention af prostatacancer
DE69615814D1 (de) Uch-15-verbindungen