PT95097A - Processo aperfeicoado para a preparacao de amino acidos ciclicos - Google Patents
Processo aperfeicoado para a preparacao de amino acidos ciclicosInfo
- Publication number
- PT95097A PT95097A PT95097A PT9509790A PT95097A PT 95097 A PT95097 A PT 95097A PT 95097 A PT95097 A PT 95097A PT 9509790 A PT9509790 A PT 9509790A PT 95097 A PT95097 A PT 95097A
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- appropriate process
- cyclic acids
- amino cyclic
- amino
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- -1 AMINO Chemical class 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
- C07C227/10—Formation of amino groups in compounds containing carboxyl groups with simultaneously increasing the number of carbon atoms in the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/12—Formation of amino and carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/22—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Indole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39905689A | 1989-08-25 | 1989-08-25 | |
| US07/564,623 US5132451A (en) | 1989-08-25 | 1990-08-10 | Process for cyclic amino acid anticonvulsant compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT95097A true PT95097A (pt) | 1991-04-18 |
| PT95097B PT95097B (pt) | 1997-04-30 |
Family
ID=27016485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT95097A PT95097B (pt) | 1989-08-25 | 1990-08-24 | Processo aperfeicoado para a preparacao de amino acidos ciclicos |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5693845A (pt) |
| EP (1) | EP0414262B1 (pt) |
| JP (1) | JP2945728B2 (pt) |
| AT (1) | ATE114637T1 (pt) |
| AU (2) | AU633612B2 (pt) |
| CA (1) | CA2023874A1 (pt) |
| DE (1) | DE69014480T2 (pt) |
| DK (1) | DK0414262T3 (pt) |
| ES (1) | ES2065446T3 (pt) |
| FI (1) | FI107914B (pt) |
| IE (1) | IE66824B1 (pt) |
| MY (1) | MY106864A (pt) |
| NO (1) | NO179407C (pt) |
| NZ (1) | NZ235044A (pt) |
| PH (2) | PH27359A (pt) |
| PT (1) | PT95097B (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4894476A (en) * | 1988-05-02 | 1990-01-16 | Warner-Lambert Company | Gabapentin monohydrate and a process for producing the same |
| FI905584L (fi) * | 1989-11-16 | 1991-05-17 | Lonza Ag | Foerfarande foer framstaellning av 1-(aminometyl)cyklohexanaettikssyra. |
| PL363155A1 (en) * | 2000-06-16 | 2004-11-15 | Teva Pharmaceutical Industries, Ltd. | Stable gabapentin having ph within a controlled range |
| DE60101476T2 (de) | 2000-06-16 | 2004-05-27 | Teva Pharmaceutical Industries Ltd. | Stabiles gabapentin, das mehr als 20 ppm chlor enthält |
| US20030119908A1 (en) * | 2001-12-21 | 2003-06-26 | Zambon Group S.P.A. | Stable gabapentin compositions |
| WO2004111256A1 (en) * | 2003-06-19 | 2004-12-23 | Pfizer Products Inc. | Biocatalytic preparation of 1-cyanocyclohexaneacetic acid |
| GB0416228D0 (en) | 2004-07-20 | 2004-08-25 | Sandoz Ind Products S A | Process for the preparation of gabapentin |
| EP2038249B1 (en) * | 2006-06-30 | 2013-09-11 | ZaCh System S.p.A. | Process for preparing gabapentin |
| JP4872950B2 (ja) | 2008-03-05 | 2012-02-08 | ソニー株式会社 | 非水電解質二次電池 |
| EP2923694B1 (en) | 2014-03-27 | 2018-11-14 | Sanovel Ilac Sanayi ve Ticaret A.S. | Oral liquid pharmaceutical solution of gabapentin |
| CN107235850B (zh) * | 2017-05-31 | 2019-07-26 | 浙江工业大学 | 利用1-氰基环己基乙酸直接合成加巴喷丁的方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2264354A (en) * | 1937-12-22 | 1941-12-02 | Ig Farbenindustrie Ag | Addition products of dienes and unsaturated esters, ketones, or nitriles |
| US2467927A (en) * | 1947-05-29 | 1949-04-19 | Goodrich Co B F | Preparation of monomeric alkyl alpha-cyano-acrylates |
| US2502412A (en) * | 1948-02-07 | 1950-04-04 | Goodrich Co B F | Preparation of vinylidene cyanide by pyrolysis of novel 4, 4-disubstituted cyclohexenes |
| US2575376A (en) * | 1949-10-21 | 1951-11-20 | Gen Mills Inc | Formyl cyclohexene nitriles and esters |
| DE1445664A1 (de) * | 1963-07-04 | 1969-11-27 | Klinke Desitin Werk | Verfahren zur Herstellung von alpha,alpha-disubstituierten Succinimiden |
| JPS4822692B1 (pt) * | 1963-12-24 | 1973-07-07 | ||
| US3515740A (en) * | 1967-02-20 | 1970-06-02 | Orville D Frampton | Cyano cyclohexenyl compounds |
| DE2460891C2 (de) * | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| US4087544A (en) * | 1974-12-21 | 1978-05-02 | Warner-Lambert Company | Treatment of cranial dysfunctions using novel cyclic amino acids |
| GB1478224A (en) * | 1975-01-24 | 1977-06-29 | Science Union & Cie | Dispiroalkanes processes for their preparation and pharma ceutical compositions containing them |
| DE2557220A1 (de) * | 1975-12-19 | 1977-06-23 | Goedecke Ag | N-substituierte spirolactame |
| DE2611690A1 (de) * | 1976-03-19 | 1977-09-22 | Goedecke Ag | Cyclische sulfonyloxyimide |
| DE2626467C2 (de) * | 1976-06-12 | 1984-11-22 | Gödecke AG, 1000 Berlin | 1-(N-Isopropylaminomethyl)-cyclohexanessigsäure, Verfahren zu deren Herstellung und diese Verbindung enthaltende Arzneimittel |
| US4226802A (en) * | 1979-10-29 | 1980-10-07 | Zoecon Corporation | 2-(4-Trifluoromethylphenylamino)-3-methylbutanoic acid esters and intermediates therefor |
| GB8606255D0 (en) * | 1986-03-13 | 1986-04-16 | Wyeth John & Brother Ltd | Nitriles |
| US4894476A (en) * | 1988-05-02 | 1990-01-16 | Warner-Lambert Company | Gabapentin monohydrate and a process for producing the same |
| YU162789A (en) * | 1988-09-01 | 1990-12-31 | Lonza Ag | 2-aza-4-(alcoxycarbonyl) spiro/4,5/decan-3-ones |
| DE3928184A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte |
-
1990
- 1990-08-22 AU AU61247/90A patent/AU633612B2/en not_active Ceased
- 1990-08-22 PH PH41066A patent/PH27359A/en unknown
- 1990-08-22 FI FI904164A patent/FI107914B/fi active IP Right Grant
- 1990-08-22 MY MYPI90001406A patent/MY106864A/en unknown
- 1990-08-23 CA CA002023874A patent/CA2023874A1/en not_active Abandoned
- 1990-08-24 ES ES90116264T patent/ES2065446T3/es not_active Expired - Lifetime
- 1990-08-24 AT AT90116264T patent/ATE114637T1/de not_active IP Right Cessation
- 1990-08-24 NO NO903732A patent/NO179407C/no not_active IP Right Cessation
- 1990-08-24 EP EP90116264A patent/EP0414262B1/en not_active Expired - Lifetime
- 1990-08-24 IE IE309490A patent/IE66824B1/en not_active IP Right Cessation
- 1990-08-24 DK DK90116264.4T patent/DK0414262T3/da active
- 1990-08-24 DE DE69014480T patent/DE69014480T2/de not_active Expired - Fee Related
- 1990-08-24 JP JP2221433A patent/JP2945728B2/ja not_active Expired - Fee Related
- 1990-08-24 NZ NZ235044A patent/NZ235044A/en unknown
- 1990-08-24 PT PT95097A patent/PT95097B/pt not_active IP Right Cessation
-
1992
- 1992-03-06 US US07/846,509 patent/US5693845A/en not_active Expired - Fee Related
- 1992-10-12 PH PH45082A patent/PH30922A/en unknown
-
1993
- 1993-01-29 AU AU32145/93A patent/AU640582B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IE903094A1 (en) | 1991-02-27 |
| MY106864A (en) | 1995-08-30 |
| AU3214593A (en) | 1993-03-25 |
| EP0414262A2 (en) | 1991-02-27 |
| CA2023874A1 (en) | 1991-02-26 |
| NO179407B (no) | 1996-06-24 |
| PH30922A (en) | 1997-12-23 |
| JPH03236359A (ja) | 1991-10-22 |
| IE66824B1 (en) | 1996-02-07 |
| AU633612B2 (en) | 1993-02-04 |
| NO179407C (no) | 1996-10-02 |
| US5693845A (en) | 1997-12-02 |
| DE69014480T2 (de) | 1995-04-20 |
| HK1000799A1 (en) | 1998-05-01 |
| ES2065446T3 (es) | 1995-02-16 |
| PH27359A (en) | 1993-06-21 |
| AU640582B2 (en) | 1993-08-26 |
| DK0414262T3 (da) | 1995-05-15 |
| NZ235044A (en) | 1994-05-26 |
| DE69014480D1 (de) | 1995-01-12 |
| FI107914B (fi) | 2001-10-31 |
| ATE114637T1 (de) | 1994-12-15 |
| EP0414262B1 (en) | 1994-11-30 |
| EP0414262A3 (en) | 1991-06-05 |
| NO903732L (no) | 1991-02-26 |
| NO903732D0 (no) | 1990-08-24 |
| PT95097B (pt) | 1997-04-30 |
| FI904164A0 (fi) | 1990-08-22 |
| AU6124790A (en) | 1991-02-28 |
| JP2945728B2 (ja) | 1999-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19901210 |
|
| MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20090731 |