PT954524E - Processo para purificar apolipoproteinas - Google Patents
Processo para purificar apolipoproteinasInfo
- Publication number
- PT954524E PT954524E PT97939315T PT97939315T PT954524E PT 954524 E PT954524 E PT 954524E PT 97939315 T PT97939315 T PT 97939315T PT 97939315 T PT97939315 T PT 97939315T PT 954524 E PT954524 E PT 954524E
- Authority
- PT
- Portugal
- Prior art keywords
- polymeric material
- surfactant
- hydrophobic
- amphiphilic compound
- atherosclerosis
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 102000007592 Apolipoproteins Human genes 0.000 title abstract 2
- 108010071619 Apolipoproteins Proteins 0.000 title abstract 2
- 239000000463 material Substances 0.000 abstract 8
- 239000004094 surface-active agent Substances 0.000 abstract 6
- 201000001320 Atherosclerosis Diseases 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 230000002209 hydrophobic effect Effects 0.000 abstract 4
- 102100029470 Apolipoprotein E Human genes 0.000 abstract 3
- 101710095339 Apolipoprotein E Proteins 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 3
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 2
- 206010040047 Sepsis Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000002093 peripheral effect Effects 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9603304A SE9603304D0 (sv) | 1996-09-11 | 1996-09-11 | Process for purifying a compound |
| US2673996P | 1996-09-26 | 1996-09-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT954524E true PT954524E (pt) | 2003-08-29 |
Family
ID=26662746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97939315T PT954524E (pt) | 1996-09-11 | 1997-09-08 | Processo para purificar apolipoproteinas |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0954524B1 (pt) |
| JP (1) | JP2001500154A (pt) |
| AT (1) | ATE236925T1 (pt) |
| AU (1) | AU729536B2 (pt) |
| CA (1) | CA2265929A1 (pt) |
| DE (1) | DE69720786T2 (pt) |
| DK (1) | DK0954524T3 (pt) |
| ES (1) | ES2197361T3 (pt) |
| NO (1) | NO323217B1 (pt) |
| NZ (1) | NZ334589A (pt) |
| PT (1) | PT954524E (pt) |
| WO (1) | WO1998011127A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7205280B2 (en) * | 1998-03-11 | 2007-04-17 | Cognosci, Inc. | Methods of suppressing microglial activation |
| ATE266672T1 (de) * | 1998-12-30 | 2004-05-15 | Folke Tjerneld | Trennungsmethode unter verwendung von flüssig- flüssig partition |
| SE9904803D0 (sv) * | 1999-12-27 | 1999-12-27 | Amersham Pharm Biotech Ab | Method for the isolation of hydrophobic proteins |
| FR2827192B1 (fr) * | 2001-07-13 | 2004-06-04 | Cognis France Sa | Preparations contenant des agents tensio-actifs non ioniques comme agents d'extraction |
| CN100357325C (zh) * | 2005-10-23 | 2007-12-26 | 王贤理 | 一种抗apoA I、apoB抗体制备方法以及用于检测apoA I、apoB的试剂盒 |
| WO2012024691A1 (en) | 2010-08-20 | 2012-02-23 | President And Fellows Of Harvard College | Multiphase systems for analysis of solid materials |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1229996B (it) * | 1989-04-20 | 1991-09-20 | Cesare Sirtori | Espressione di apolipoproteina ai e apolipoproteina ai-milano in lievito e composizioni farmaceutiche che contengono dette apolipoproteine. |
| WO1993000443A1 (en) * | 1991-06-26 | 1993-01-07 | Bio-Technology General Corp. | Purification of recombinant apolipoprotein e from bacteria |
-
1997
- 1997-09-08 AT AT97939315T patent/ATE236925T1/de not_active IP Right Cessation
- 1997-09-08 WO PCT/SE1997/001502 patent/WO1998011127A1/en not_active Ceased
- 1997-09-08 DE DE69720786T patent/DE69720786T2/de not_active Expired - Fee Related
- 1997-09-08 JP JP10513557A patent/JP2001500154A/ja not_active Withdrawn
- 1997-09-08 DK DK97939315T patent/DK0954524T3/da active
- 1997-09-08 AU AU41430/97A patent/AU729536B2/en not_active Ceased
- 1997-09-08 NZ NZ334589A patent/NZ334589A/xx unknown
- 1997-09-08 EP EP97939315A patent/EP0954524B1/en not_active Expired - Lifetime
- 1997-09-08 PT PT97939315T patent/PT954524E/pt unknown
- 1997-09-08 CA CA002265929A patent/CA2265929A1/en not_active Abandoned
- 1997-09-08 ES ES97939315T patent/ES2197361T3/es not_active Expired - Lifetime
-
1999
- 1999-03-11 NO NO19991208A patent/NO323217B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0954524T3 (da) | 2003-08-04 |
| DE69720786T2 (de) | 2003-11-06 |
| NZ334589A (en) | 2000-07-28 |
| NO991208D0 (no) | 1999-03-11 |
| ES2197361T3 (es) | 2004-01-01 |
| NO323217B1 (no) | 2007-01-29 |
| AU4143097A (en) | 1998-04-02 |
| EP0954524A1 (en) | 1999-11-10 |
| DE69720786D1 (de) | 2003-05-15 |
| CA2265929A1 (en) | 1998-03-19 |
| NO991208L (no) | 1999-05-11 |
| JP2001500154A (ja) | 2001-01-09 |
| EP0954524B1 (en) | 2003-04-09 |
| WO1998011127A1 (en) | 1998-03-19 |
| ATE236925T1 (de) | 2003-04-15 |
| AU729536B2 (en) | 2001-02-01 |
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