PT97061A - Metodo para a utilizacao de tenidap como inibidor da activacao de colagenase e da actividade de mieloperoxidase - Google Patents

Metodo para a utilizacao de tenidap como inibidor da activacao de colagenase e da actividade de mieloperoxidase

Info

Publication number: PT97061A
Authority: PT; Portugal
Prior art keywords: colagenase; tenidap; myeloperoxidase; inhibitor; activation
Prior art date: 1990-03-19

Application number

PT97061A

Other languages

English (en)

Other versions

PT97061B (pt

Inventor

Warren Darrel Blackburn Jr

Leland David Loose

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-03-19

Filing date

1991-03-18

Publication date

1991-10-31

1991-03-18 Application filed by Pfizer filed Critical Pfizer

1991-10-31 Publication of PT97061A publication Critical patent/PT97061A/pt

1998-07-31 Publication of PT97061B publication Critical patent/PT97061B/pt

Links

102000003896 Myeloperoxidases Human genes 0.000 title 1
108090000235 Myeloperoxidases Proteins 0.000 title 1
230000004913 activation Effects 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1
LXIKEPCNDFVJKC-QXMHVHEDSA-N tenidap Chemical compound C12=CC(Cl)=CC=C2N(C(=O)N)C(=O)\C1=C(/O)C1=CC=CS1 LXIKEPCNDFVJKC-QXMHVHEDSA-N 0.000 title 1
229960003676 tenidap Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Obesity (AREA)
Diabetes (AREA)
Ophthalmology & Optometry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

PT97061A 1990-03-19 1991-03-18 Metodo para a utilizacao de tenidap como inibidor da activacao de colagenase e da actividade de mieloperoxidase PT97061B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/495,868 US5008283A (en)	1990-03-19	1990-03-19	Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase

Publications (2)

Publication Number	Publication Date
PT97061A true PT97061A (pt)	1991-10-31
PT97061B PT97061B (pt)	1998-07-31

Family

ID=23970312

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT97061A PT97061B (pt)	1990-03-19	1991-03-18	Metodo para a utilizacao de tenidap como inibidor da activacao de colagenase e da actividade de mieloperoxidase

Country Status (14)

Country	Link
US (1)	US5008283A (pt)
EP (1)	EP0448253A3 (pt)
JP (1)	JPH04234815A (pt)
KR (1)	KR930010581B1 (pt)
AU (2)	AU625409B2 (pt)
CA (1)	CA2038409C (pt)
HU (1)	HUT60623A (pt)
IE (1)	IE910860A1 (pt)
IL (1)	IL97521A (pt)
MY (1)	MY107235A (pt)
NZ (1)	NZ237451A (pt)
PT (1)	PT97061B (pt)
SG (1)	SG48397A1 (pt)
ZA (1)	ZA911979B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5122534A (en) *	1991-02-08	1992-06-16	Pfizer Inc.	Use of tenidap to reduce total serum cholesterol, ldl cholesterol and triglycerides
TW438798B (en) *	1992-10-07	2001-06-07	Pfizer	3-substituted 2-oxindole-1-carboxamide pharmaceutical compositions
US5298522A (en) *	1993-01-22	1994-03-29	Pfizer Inc.	6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide as an analgesic and anti-inflammatory agent while maintaining a normal urine protein/creatinine ratio
ES2076106B1 (es) *	1993-08-26	1996-06-16	Pfizer	Composiciones farmaceuticas a base de 2-oxindol-1-carboxamidas 3-sustituidas
US5795902A (en) *	1993-09-02	1998-08-18	Pfizer Inc.	3-substituted 2-oxindole-1 carboxamide pharmaceutical compositions
US5516699A (en) *	1994-02-16	1996-05-14	Institute Of Molecular Biology, Inc.	Pyridinoline crosslinks as markers of periodontal and peri-implant disease activity
US5545656A (en) *	1995-04-05	1996-08-13	Pfizer Inc.	2-Oxidole-1-carboxamide pharmaceutical agents for the treatment of alzheimer's disease
US5827840A (en) *	1996-08-01	1998-10-27	The Research Foundation Of State University Of New York	Promotion of wound healing by chemically-modified tetracyclines
AU4084599A (en) *	1998-05-18	1999-12-06	Oklahoma Medical Research Foundation	Resveratrol inhibition of myeloperoxidase
US6544556B1 (en)	2000-09-11	2003-04-08	Andrx Corporation	Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
PT2026651E (pt)	2006-03-08	2013-06-04	Cortria Corp	Terapia combinada com inibidores cox não selectivos para prevenir lesões gástricas relacionadas com a cox

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4556672A (en) *	1984-03-19	1985-12-03	Pfizer Inc.	3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4678802A (en) *	1985-07-09	1987-07-07	Pfizer Inc.	1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents
RO105052B1 (en) *	1987-02-02	1994-12-01	Pfizer	Producing process for the crystalline sodium salt, anhydre, of 5-chlorine-3-(2-tenoil)-2-oxindol-1-carboxamide
DE3852145T2 (de) *	1987-02-18	1995-04-06	Beecham Group Plc	Indolderivate, Verfahren zu deren Herstellung und pharmazeutische Präparate, die diese enthalten.
US4853409A (en) *	1988-04-13	1989-08-01	Pfizer Inc.	3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function
US4861794A (en) *	1988-04-13	1989-08-29	Pfizer Inc.	3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis
DE3814504A1 (de) *	1988-04-29	1989-11-09	Bayer Ag	(alpha)-substituierte 4-(chinolin-2-yl-methoxy)phenylessigsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5006547A (en) *	1990-03-19	1991-04-09	Pfizer Inc.	Tenidap as an inhibitor of the release of elastase by neutrophils

1990
- 1990-03-19 US US07/495,868 patent/US5008283A/en not_active Expired - Lifetime
1991
- 1991-03-07 EP EP19910301890 patent/EP0448253A3/en not_active Withdrawn
- 1991-03-07 SG SG1996009351A patent/SG48397A1/en unknown
- 1991-03-12 IL IL9752191A patent/IL97521A/en not_active IP Right Cessation
- 1991-03-15 IE IE086091A patent/IE910860A1/en unknown
- 1991-03-15 NZ NZ237451A patent/NZ237451A/en unknown
- 1991-03-15 CA CA002038409A patent/CA2038409C/en not_active Expired - Fee Related
- 1991-03-18 PT PT97061A patent/PT97061B/pt not_active IP Right Cessation
- 1991-03-18 HU HU91872A patent/HUT60623A/hu unknown
- 1991-03-18 AU AU73587/91A patent/AU625409B2/en not_active Ceased
- 1991-03-18 ZA ZA911979A patent/ZA911979B/xx unknown
- 1991-03-18 KR KR1019910004236A patent/KR930010581B1/ko not_active Expired - Fee Related
- 1991-03-18 MY MYPI91000438A patent/MY107235A/en unknown
- 1991-03-19 JP JP3130750A patent/JPH04234815A/ja active Pending
1992
- 1992-07-09 AU AU19574/92A patent/AU637745B2/en not_active Ceased

Also Published As

Publication number	Publication date
HU910872D0 (en)	1991-09-30
AU625409B2 (en)	1992-07-09
IL97521A0 (en)	1992-06-21
KR930010581B1 (ko)	1993-10-30
ZA911979B (en)	1992-10-28
PT97061B (pt)	1998-07-31
EP0448253A2 (en)	1991-09-25
EP0448253A3 (en)	1992-04-01
AU7358791A (en)	1991-12-12
JPH04234815A (ja)	1992-08-24
AU1957492A (en)	1992-09-10
IL97521A (en)	1995-12-31
US5008283A (en)	1991-04-16
IE910860A1 (en)	1991-09-25
CA2038409C (en)	1995-01-24
AU637745B2 (en)	1993-06-03
HUT60623A (en)	1992-10-28
NZ237451A (en)	1997-02-24
KR910016326A (ko)	1991-11-05
SG48397A1 (en)	1998-04-17
MY107235A (en)	1995-10-31

Legal Events

Date

Code

Title

Description

1991-10-31

BB1A

Laying open of patent application

Effective date: 19910710

1998-07-31

FG3A

Patent granted, date of granting

Effective date: 19980415

2000-02-29

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19991031

Publication	Publication Date	Title
BR8904593A (pt)	1990-04-24	Estrutura absorvente unificada,dispositivo adequado para incontinencia,tampao e revestimento de ferimento
HUT77662A (hu)	1998-07-28	Kezelt fedőlappal ellátott pelenka
FI952703L (fi)	1995-12-04	Suuren aktiivisuuden etyleenisilektiiviset metalloseenit
FI961158L (fi)	1996-03-13	Puheaktiivisuuden ilmaisin
ATA903993A (de)	2001-01-15	Pth-analoga
FI956338A0 (fi)	1995-12-29	Absorboivia tuotteita
DE69330076D1 (de)	2001-05-10	Absorbierender Gegenstand
DE69332034D1 (de)	2002-07-18	Absorbierender Gegenstand
FI943528A7 (fi)	1994-07-27	Absorbenttituotteita
DE68929358D1 (de)	2002-01-31	Absorbierender Gegenstand
BR9500820A (pt)	1995-10-24	Artigo absorvente
BR9510278A (pt)	1999-03-30	Artigo absorvente
BR9510120A (pt)	1999-01-05	Artigo absorvente
BR9508299A (pt)	1998-07-14	Artigo absorvente
MX9205113A (es)	1993-04-01	Agentes de recubrimiento acuosos y procedimiento para su obtencion
DK0625895T3 (da)	1998-04-20	Absorptionslegeme til en absorberende artikel
DE69514816D1 (de)	2000-03-02	Absorbierender artikel
NO890503L (no)	1989-09-22	Vandig blekemiddel.
PT97061A (pt)	1991-10-31	Metodo para a utilizacao de tenidap como inibidor da activacao de colagenase e da actividade de mieloperoxidase
DE69522771D1 (de)	2001-10-25	Absorbierender artikel
BR9508567A (pt)	1997-08-12	Artigo absorvente
NO901265D0 (no)	1990-03-19	Gass- og luktabsorberende anordning.
FI943871A0 (fi)	1994-08-23	Pidätyskyvyttömyyssuoja
BR9510116A (pt)	1999-01-05	Artigo absorvente
KR960702291A (ko)	1996-04-27	흡수성 물품