PT97624A - Processo para a preparacao de derivados de galactopiranosidos fosforilados com uma actividade potencial identica a da insulina - Google Patents

Processo para a preparacao de derivados de galactopiranosidos fosforilados com uma actividade potencial identica a da insulina

Info

Publication number: PT97624A
Authority: PT; Portugal
Prior art keywords: derivatives; insulin; preparation; galactopiranoside; phosphorylated
Prior art date: 1990-05-10

Application number

PT97624A

Other languages

English (en)

Other versions

PT97624B (pt

Inventor

Manuel Martin Lomas

Jose Maria Mato De La Paz

Original Assignee

Europharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-05-10

Filing date

1991-05-09

Publication date

1992-02-28

1991-05-09 Application filed by Europharma Sa filed Critical Europharma Sa

1992-02-28 Publication of PT97624A publication Critical patent/PT97624A/pt

1998-08-31 Publication of PT97624B publication Critical patent/PT97624B/pt

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
102000004877 Insulin Human genes 0.000 title 1
108090001061 Insulin Proteins 0.000 title 1
229940125396 insulin Drugs 0.000 title 1
230000003334 potential effect Effects 0.000 title 1
229910019142 PO4 Inorganic materials 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000002256 galaktoses Polymers 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000002608 insulinlike Effects 0.000 abstract 1
235000021317 phosphate Nutrition 0.000 abstract 1
150000003013 phosphoric acid derivatives Chemical class 0.000 abstract 1
159000000000 sodium salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
- C07H11/04—Phosphates; Phosphites; Polyphosphates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Crystallography & Structural Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

PT97624A 1990-05-10 1991-05-09 Processo para a preparacao de derivados de galactopiranosidos fosforilados com uma actividade potencial identica a da insulina PT97624B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ES9001306A ES2019839A6 (es)	1990-05-10	1990-05-10	Procedimiento de obtencion de derivados polifosforilados de galactosa con actividad insulinica.

Publications (2)

Publication Number	Publication Date
PT97624A true PT97624A (pt)	1992-02-28
PT97624B PT97624B (pt)	1998-08-31

Family

ID=8267236

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT97624A PT97624B (pt)	1990-05-10	1991-05-09	Processo para a preparacao de derivados de galactopiranosidos fosforilados com uma actividade potencial identica a da insulina

Country Status (7)

Country	Link
EP (1)	EP0456948B1 (pt)
AT (1)	ATE127125T1 (pt)
DE (2)	DE456948T1 (pt)
ES (1)	ES2019839A6 (pt)
GR (1)	GR920300068T1 (pt)
IE (1)	IE910491A1 (pt)
PT (1)	PT97624B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0665080A (ja) *	1992-03-10	1994-03-08	Godo Shiyusei Kk	α−グルコシダ−ゼ阻害剤を含有する、過血糖付随疾患の予防・治療剤、および保健食
SE9403137D0 (sv)	1994-09-20	1994-09-20	Perstorp Ab	Derivatives of carbohydrates and compositions containing them
WO2012045009A2 (en) *	2010-09-30	2012-04-05	Normoxys, Inc.	Polyphosphate and pyrophosphate derivative of saccharides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL8302353A (nl) *	1983-07-01	1985-02-01	Stichting Katholieke Univ	Fosforyleringsmiddel; werkwijze voor het bereiden daarvan; werkwijze voor het fosforyleren van een organische hydroxyl- of amineverbinding.
US4873355A (en) *	1987-05-29	1989-10-10	E. I. Du Pont De Nemours And Company	Process for regioselectively preparing phosphorylated inositols and other cyclitols
EP0354323A3 (en) *	1988-08-12	1990-06-13	American Cyanamid Company	Antidiabetic phosphates

1990
- 1990-05-10 ES ES9001306A patent/ES2019839A6/es not_active Expired - Lifetime
- 1990-12-28 DE DE199090500129T patent/DE456948T1/de active Pending
- 1990-12-28 AT AT90500129T patent/ATE127125T1/de not_active IP Right Cessation
- 1990-12-28 DE DE69022033T patent/DE69022033D1/de not_active Expired - Lifetime
- 1990-12-28 EP EP90500129A patent/EP0456948B1/en not_active Expired - Lifetime
1991
- 1991-02-13 IE IE049191A patent/IE910491A1/en unknown
- 1991-05-09 PT PT97624A patent/PT97624B/pt not_active IP Right Cessation
1992
- 1992-08-31 GR GR92300068T patent/GR920300068T1/el unknown

Also Published As

Publication number	Publication date
GR920300068T1 (en)	1992-08-31
ES2019839A6 (es)	1991-07-01
IE910491A1 (en)	1991-11-20
EP0456948B1 (en)	1995-08-30
EP0456948A2 (en)	1991-11-21
DE69022033D1 (de)	1995-10-05
ATE127125T1 (de)	1995-09-15
PT97624B (pt)	1998-08-31
EP0456948A3 (en)	1992-07-29
DE456948T1 (de)	1992-05-21

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Legal Events

Date

Code

Title

Description

1992-02-28

BB1A

Laying open of patent application

Effective date: 19911022

1998-08-31

FG3A

Patent granted, date of granting

Effective date: 19980521

2000-03-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19991130