PT98310A - Processo de recombinacao homologa para identificacao e isolamento dum fragmento pretendido de adn a partir de uma biblioteca de fragmentos - Google Patents

Processo de recombinacao homologa para identificacao e isolamento dum fragmento pretendido de adn a partir de uma biblioteca de fragmentos

Info

Publication number
PT98310A
PT98310A PT98310A PT9831091A PT98310A PT 98310 A PT98310 A PT 98310A PT 98310 A PT98310 A PT 98310A PT 9831091 A PT9831091 A PT 9831091A PT 98310 A PT98310 A PT 98310A
Authority
PT
Portugal
Prior art keywords
fragment
pretended
isolation
identification
approval process
Prior art date
Application number
PT98310A
Other languages
English (en)
Other versions
PT98310B (pt
Inventor
Douglas A Treco
Allan M Miller
Original Assignee
Transkaryotic Therapies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transkaryotic Therapies Inc filed Critical Transkaryotic Therapies Inc
Publication of PT98310A publication Critical patent/PT98310A/pt
Publication of PT98310B publication Critical patent/PT98310B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1082Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • C12N15/902Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/905Stable introduction of foreign DNA into chromosome using homologous recombination in yeast
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigation Of Foundation Soil And Reinforcement Of Foundation Soil By Compacting Or Drainage (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Warehouses Or Storage Devices (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PT98310A 1990-07-13 1991-07-12 Processo de recombinacao homologa para identificacao e isolamento dum fragmento pretendido de adn a partir de uma biblioteca de fragmentos PT98310B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55218390A 1990-07-13 1990-07-13

Publications (2)

Publication Number Publication Date
PT98310A true PT98310A (pt) 1992-05-29
PT98310B PT98310B (pt) 1999-01-29

Family

ID=24204264

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98310A PT98310B (pt) 1990-07-13 1991-07-12 Processo de recombinacao homologa para identificacao e isolamento dum fragmento pretendido de adn a partir de uma biblioteca de fragmentos

Country Status (16)

Country Link
US (1) US5783385A (pt)
EP (1) EP0539490B1 (pt)
JP (1) JPH05508547A (pt)
KR (1) KR930701625A (pt)
AT (1) ATE130049T1 (pt)
AU (2) AU8299191A (pt)
CA (1) CA2086092A1 (pt)
DE (1) DE69114500T2 (pt)
ES (1) ES2080957T3 (pt)
IE (1) IE63212B1 (pt)
IL (1) IL98822A0 (pt)
MX (1) MX9100215A (pt)
MY (1) MY106504A (pt)
NZ (1) NZ238957A (pt)
PT (1) PT98310B (pt)
WO (1) WO1992001069A1 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8299191A (en) * 1990-07-13 1992-02-04 Transkaryotic Therapies, Inc. Library screening method
MX9206979A (es) * 1991-12-04 1993-07-01 Novo Nordisk As Metodo de clonacion de proteinas en levaduras
FR2689905B1 (fr) * 1992-04-13 1995-07-13 Orsan Procede de clonage d'une sequence d'adn codant pour une nadph cytochrome p450 reductase et sequences d'adn codant pour une nadph-cytochrome p450 reductase, notamment de plantes.
US5792632A (en) * 1992-05-05 1998-08-11 Institut Pasteur Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
US5643763A (en) * 1994-11-04 1997-07-01 Genpharm International, Inc. Method for making recombinant yeast artificial chromosomes by minimizing diploid doubling during mating
US7883872B2 (en) * 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
WO2000020555A2 (en) * 1998-10-06 2000-04-13 Aarl Inc Transformation system in the field of filamentous fungal hosts: in chrysosporium
US5811381A (en) * 1996-10-10 1998-09-22 Mark A. Emalfarb Cellulase compositions and methods of use
CA2273852C (en) 1996-12-06 2009-09-29 Amgen Inc. Combination therapy using an il-1 inhibitor for treating il-1 mediated diseases
US6897066B1 (en) * 1997-09-26 2005-05-24 Athersys, Inc. Compositions and methods for non-targeted activation of endogenous genes
US7316923B1 (en) 1997-09-26 2008-01-08 Athersys, Inc. Compositions and methods for non-targeted activation of endogenous genes
US6867189B2 (en) * 2001-07-26 2005-03-15 Genset S.A. Use of adipsin/complement factor D in the treatment of metabolic related disorders
US9057061B2 (en) 2003-12-23 2015-06-16 Novozymes Biopharma Dk A/S Gene expression technique
GB0329722D0 (en) * 2003-12-23 2004-01-28 Delta Biotechnology Ltd Modified plasmid and use thereof
GB0329681D0 (en) * 2003-12-23 2004-01-28 Delta Biotechnology Ltd Gene expression technique
EP1732653A2 (en) * 2004-03-05 2006-12-20 Alumina Micro LLC Selective bonding for forming a microvalve
NZ554824A (en) 2004-10-22 2010-10-29 Revivicor Inc Porcines that lack endogenous antibody chains and express exogenous immunoglobulins
US9862956B2 (en) 2006-12-10 2018-01-09 Danisco Us Inc. Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
US8680252B2 (en) 2006-12-10 2014-03-25 Dyadic International (Usa), Inc. Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
CA2736661A1 (en) * 2007-09-07 2009-03-12 Dyadic International, Inc. Novel fungal enzymes
DK2348827T3 (en) 2008-10-27 2015-07-20 Revivicor Inc IMMUNICIPLY COMPROMATED PETS

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038143A (en) * 1973-10-29 1977-07-26 The Regents Of The University Of Michigan Test kit for the genetic detection of microorganisms
US4745057A (en) * 1984-05-18 1988-05-17 Eli Lilly And Company Method, vectors and transformants for high expression of heterologous polypeptides in yeast
CA1293460C (en) * 1985-10-07 1991-12-24 Brian Lee Sauer Site-specific recombination of dna in yeast
US4818700A (en) * 1985-10-25 1989-04-04 Phillips Petroleum Company Pichia pastoris argininosuccinate lyase gene and uses thereof
US4889806A (en) * 1987-04-15 1989-12-26 Washington University Large DNA cloning system based on yeast artificial chromosomes
AU614121B2 (en) * 1988-05-04 1991-08-22 Novartis Ag Improvements in the production of polypeptides
GB8920211D0 (en) * 1989-09-07 1989-10-18 Ici Plc Diagnostic method
GB8921791D0 (en) * 1989-09-27 1989-11-08 Imp Cancer Res Tech Disease gene
AU8299191A (en) * 1990-07-13 1992-02-04 Transkaryotic Therapies, Inc. Library screening method
US5580734A (en) * 1990-07-13 1996-12-03 Transkaryotic Therapies, Inc. Method of producing a physical map contigous DNA sequences
DE69127552D1 (de) * 1991-08-02 1997-10-09 Transkaryotic Therapies Inc Methode zum screening einer dna bibliothek

Also Published As

Publication number Publication date
ATE130049T1 (de) 1995-11-15
DE69114500T2 (de) 1996-06-13
MY106504A (en) 1995-06-30
NZ238957A (en) 1994-04-27
JPH05508547A (ja) 1993-12-02
KR930701625A (ko) 1993-06-12
AU689015B2 (en) 1998-03-19
DE69114500D1 (de) 1995-12-14
IE63212B1 (en) 1995-04-05
CA2086092A1 (en) 1992-01-14
AU8299191A (en) 1992-02-04
AU4449396A (en) 1996-06-20
EP0539490B1 (en) 1995-11-08
EP0539490A1 (en) 1993-05-05
ES2080957T3 (es) 1996-02-16
IL98822A0 (en) 1992-07-15
US5783385A (en) 1998-07-21
PT98310B (pt) 1999-01-29
WO1992001069A1 (en) 1992-01-23
IE912470A1 (en) 1992-01-15
MX9100215A (es) 1992-02-28

Similar Documents

Publication Publication Date Title
NZ238957A (en) An homologous-recombinant method for identifying and isolating a target dna fragment from a dna fragment library
CY1108920T1 (el) Χαρακτηρισμος της γονιδιακης λειτουργιας με τη χρηση αναστολης δικλωνου rna
FR19C1020I1 (fr) Nouvelles molecules b7-4 et leurs utilisations
DE69730235D1 (de) Neuartige Verfahren und Zusammensetzungen zur Entdeckung von neuen multimerischen Molekülen, basierend auf einer kombinatorisichen Bibliothek
CA2366559A1 (en) Protein isolation and analysis
DK1143006T3 (da) Vektorer/DNA-sekvenser fra humane kombinatoriske antistofbiblioteker
EP0777750A4 (en) HIGH SALES METHOD FOR DETECTING SEQUENCES OR GENETIC CHANGES IN NUCLEIC ACIDS
CN112553695B (zh) 鉴定靶蛋白染色质结合图谱的快速建库方法
ATE224454T1 (de) Drei hybriden screening test
ATE282717T1 (de) Neuartiges verfahren zur identifizierung von klonen mit einer gewünschten biologischen eigenschaft, ausgehend von einer expressionsgenbank
ES2099981T3 (es) Factores neurotroficos ciliares modificados.
WO2002010438A3 (en) Serial analysis of transcript expression using long tags
ATE108205T1 (de) Rekombinantverfahren zur herstellung von serinproteaseinhibitoren, sowie dns-sequenzen dazu.
WO2002006834A3 (en) Nested sorting and high throughput screening
DE69823607D1 (de) Verfahren zur Datenkomprimierung unter Verwendung von Zeichenkettenanpassung
NO20010300D0 (no) Nye fremgangsmåter for identifisering av ligand og målbiomolekyler
WO2003073351A3 (en) Screening process
FR2693209B1 (fr) Procédé de détermination de la taille en nucléotides de fragments d'ADN.
MX9200096A (es) Metodo de barrido de bancos.
DE69105811D1 (de) Verfahren zur Extraktion von bestimmten Nukleinsäurefragmenten.
NZ511623A (en) Methods of identifying antigen gene sequences from Mycoplasma
DE50308017D1 (de) Verfahren zur extraktion von proteinen
WO2001048247A3 (en) METHOD FOR GENERATION OF LONGER cDNA FRAGMENTS FROM SAGE TAGS FOR GENE IDENTIFICATION
DK1299532T3 (da) Forbedrende kombinatoriske biblioteker ved rekombination i gær og analysefremgangsmåder
DE69840502D1 (de) Zubereitungen und verfahren zur aktivierung bestimmter gene

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920115

FG3A Patent granted, date of granting

Effective date: 19981002

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20000430