PT98711A - Metodo para a preparacao de alaglu-igf-1 e para a sua renaturacao e metodo para a preparacao de igf-1 humano - Google Patents

Metodo para a preparacao de alaglu-igf-1 e para a sua renaturacao e metodo para a preparacao de igf-1 humano

Info

Publication number
PT98711A
PT98711A PT98711A PT9871191A PT98711A PT 98711 A PT98711 A PT 98711A PT 98711 A PT98711 A PT 98711A PT 9871191 A PT9871191 A PT 9871191A PT 98711 A PT98711 A PT 98711A
Authority
PT
Portugal
Prior art keywords
igf
preparation
renaturation
alaglu
glu
Prior art date
Application number
PT98711A
Other languages
English (en)
Other versions
PT98711B (pt
Inventor
Lars Skriver
Kim Ry Hejnaes
Henrik Dalboge
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK198990A external-priority patent/DK198990D0/da
Priority claimed from DK249790A external-priority patent/DK249790D0/da
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of PT98711A publication Critical patent/PT98711A/pt
Publication of PT98711B publication Critical patent/PT98711B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT98711A 1990-08-20 1991-08-19 Metodo para a preparacao de alaglu-igf-1 e para a sua renaturacao e metodo para a preparacao de igf-1 humano PT98711B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK198990A DK198990D0 (da) 1990-08-20 1990-08-20 Biologisk aktivt polypeptid og fremgangsmaade til omdannelse af dette til et modent protein
DK249790A DK249790D0 (da) 1990-10-16 1990-10-16 Fremgangsmaade til renaturering af et humant protein

Publications (2)

Publication Number Publication Date
PT98711A true PT98711A (pt) 1992-07-31
PT98711B PT98711B (pt) 1999-01-29

Family

ID=26066263

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98711A PT98711B (pt) 1990-08-20 1991-08-19 Metodo para a preparacao de alaglu-igf-1 e para a sua renaturacao e metodo para a preparacao de igf-1 humano

Country Status (9)

Country Link
US (3) US5459052A (pt)
EP (1) EP0545999B1 (pt)
JP (1) JPH06500084A (pt)
AT (1) ATE154073T1 (pt)
AU (1) AU8417091A (pt)
DE (1) DE69126434D1 (pt)
IE (1) IE912935A1 (pt)
PT (1) PT98711B (pt)
WO (1) WO1992003477A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4105480A1 (de) * 1991-02-21 1992-08-27 Boehringer Mannheim Gmbh Verbesserte aktivierung von rekombinanten proteinen
US5407810A (en) * 1993-08-20 1995-04-18 Genentech, Inc. Aqueous multiple-phase isolation of polypeptide
US5663304A (en) * 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
US5446024A (en) * 1993-12-17 1995-08-29 Genentech, Inc. Purification of insulin-like growth factor
US6756484B1 (en) * 1995-04-14 2004-06-29 Cephalon, Inc. IGF-I purification process
US5650496A (en) * 1995-04-14 1997-07-22 Cephalon, Inc. IGF-I purification process
US5747236A (en) 1996-01-26 1998-05-05 Eastman Kodak Company Silver halide light sensitive emulsion layer having enhanced photographic sensitivity
US5747235A (en) 1996-01-26 1998-05-05 Eastman Kodak Company Silver halide light sensitive emulsion layer having enhanced photographic sensitivity
EP0786692B1 (en) 1996-01-26 2004-11-17 Eastman Kodak Company Silver halide light sensitive emulsion layer having enhanced photographic sensitivity
DE69821294T2 (de) * 1997-07-25 2004-11-18 Eastman Kodak Co. Lichtempfindliche Silberhalogenidemulsionsschicht mit verstärkter photographischer Empfindlichkeit
US5994051A (en) * 1997-07-25 1999-11-30 Eastman Kodak Company Silver halide light sensitive emulsion layer having enhanced photographic sensitivity
EP0893732B1 (en) * 1997-07-25 2003-01-22 Eastman Kodak Company Silver halide light sensitive emulsion layer having enhanced photographic sensitivity
US6265542B1 (en) * 1997-10-24 2001-07-24 Genentech, Inc. Purification of molecules
US6514682B1 (en) 2001-06-20 2003-02-04 Eastman Kodak Company Speed addendum for photographic emulsions
US20030158593A1 (en) * 2002-02-19 2003-08-21 Heilman Marlin S. Cardiac garment
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
CN104619727B (zh) 2012-06-25 2019-04-05 布里格姆及妇女医院股份有限公司 靶向治疗

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3537708A1 (de) * 1985-10-23 1987-04-23 Boehringer Mannheim Gmbh Verfahren zur aktivierung von t-pa nach expression in prokaryonten
US4766205A (en) * 1985-11-13 1988-08-23 Beatrice Companies, Inc. Method for isolation of recombinant polypeptides in biologically active forms
DE3611817A1 (de) * 1986-04-08 1987-10-15 Boehringer Mannheim Gmbh Verfahren zur renaturierung von proteinen
DE3618817A1 (de) * 1986-06-04 1987-12-10 Behringwerke Ag Verfahren zur gewinnung aktiver proteine aus einer biologisch inaktiven form
IL86090A (en) * 1987-04-16 1993-03-15 Cetus Oncology Corp Production of purified, biologically active, bacterially produced recombinant human csf-1
US4961969A (en) * 1987-05-11 1990-10-09 Cetus Corporation Process for recovering microbially produced interferon-β
EP0371041A1 (en) 1987-06-24 1990-06-06 Novo Nordisk A/S A process for preparing a protein or polypeptide, a dna sequence coding for the polypeptide, a microorganism containing the dna sequence as well as the polypeptide and its use as a pharmaceutical preparation
JPH01132598A (ja) * 1987-10-14 1989-05-25 Pitman Moore Inc 変性剤溶液中に含まれる組換え蛋白質における分子内ジスルフィド結合の生成を促進する方法
JP2517100B2 (ja) * 1989-03-08 1996-07-24 協和醗酵工業株式会社 ヒト顆粒球コロニ―刺激因子活性を有する蛋白質の精製法
US5158875A (en) * 1989-08-25 1992-10-27 Amgen Inc. Production of biologically active insulin-like growth factor i from high expression host cell systems

Also Published As

Publication number Publication date
IE912935A1 (en) 1992-02-26
EP0545999B1 (en) 1997-06-04
PT98711B (pt) 1999-01-29
ATE154073T1 (de) 1997-06-15
AU8417091A (en) 1992-03-17
US5708134A (en) 1998-01-13
JPH06500084A (ja) 1994-01-06
WO1992003477A1 (en) 1992-03-05
EP0545999A1 (en) 1993-06-16
DE69126434D1 (de) 1997-07-10
US5691168A (en) 1997-11-25
US5459052A (en) 1995-10-17

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920406

FG3A Patent granted, date of granting

Effective date: 19981026

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20000430