PT98720A - Processo para a preparacao de derivados de fosfolipidos de nucleosidos e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de derivados de fosfolipidos de nucleosidos e de composicoes farmaceuticas que os contem

Info

Publication number
PT98720A
PT98720A PT98720A PT9872091A PT98720A PT 98720 A PT98720 A PT 98720A PT 98720 A PT98720 A PT 98720A PT 9872091 A PT9872091 A PT 9872091A PT 98720 A PT98720 A PT 98720A
Authority
PT
Portugal
Prior art keywords
preparation
nucleosides
pharmaceutical compositions
compositions containing
phospholipid derivatives
Prior art date
Application number
PT98720A
Other languages
English (en)
Other versions
PT98720B (pt
Inventor
Alfred Mertens
Harald Zilch
Dieter Herrmann
Herbert Leinert
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25896049&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT98720(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of PT98720A publication Critical patent/PT98720A/pt
Publication of PT98720B publication Critical patent/PT98720B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PT98720A 1990-08-20 1991-08-20 Processo para a preparacao de derivados de fosfolipidos de nucleosidos e de composicoes farmaceuticas que os contem PT98720B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4026265A DE4026265A1 (de) 1990-08-20 1990-08-20 Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
US08/661,038 US5756711A (en) 1990-08-20 1996-06-10 Phospholipid derivatives of nucleosides and their use as anti-viral medicaments

Publications (2)

Publication Number Publication Date
PT98720A true PT98720A (pt) 1992-07-31
PT98720B PT98720B (pt) 1999-02-26

Family

ID=25896049

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98720A PT98720B (pt) 1990-08-20 1991-08-20 Processo para a preparacao de derivados de fosfolipidos de nucleosidos e de composicoes farmaceuticas que os contem

Country Status (15)

Country Link
US (1) US5756711A (pt)
EP (1) EP0545966B1 (pt)
CN (1) CN1032258C (pt)
AT (1) ATE114316T1 (pt)
CA (1) CA2090024C (pt)
DE (2) DE4026265A1 (pt)
DK (1) DK0545966T3 (pt)
ES (1) ES2066461T3 (pt)
FI (1) FI104176B (pt)
HK (1) HK35597A (pt)
IE (1) IE64374B1 (pt)
NO (1) NO179710C (pt)
PT (1) PT98720B (pt)
SK (1) SK281826B6 (pt)
WO (1) WO1992003462A1 (pt)

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DE4204031A1 (de) * 1992-02-12 1993-08-19 Boehringer Mannheim Gmbh Neue lipidphosphonsaeure-nucleosid-konjugate sowie deren verwendung als antivirale arzneimittel
DE4226279A1 (de) * 1992-08-08 1994-02-10 Boehringer Mannheim Gmbh Liponucleotide von Seco-Nucleosiden, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel
US6080734A (en) * 1992-08-08 2000-06-27 Roche Diagnostic Gmbh Liponucleotides of seco-nucleosides, their production as well as their use as antiviral pharmaceutical agents
DE69431596T4 (de) * 1993-06-10 2003-10-30 University Of North Carolina At Chapel Hill, Chapel Hill (phospho)lipide zum bekämpfen einer hepatitis b-infektion
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DE4418690A1 (de) * 1994-05-28 1996-01-11 Boehringer Mannheim Gmbh Neue Lipidester von Nucleosid-Monophosphaten und deren Verwendung als immunsuppressive Arzneimittel
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US7135584B2 (en) 1995-08-07 2006-11-14 Wake Forest University Lipid analogs for treating viral infections
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DE19505168A1 (de) * 1995-02-16 1996-08-22 Boehringer Mannheim Gmbh Spezifische Lipidkonjugate von Nucleosid-Diphosphonaten und deren Verwendung als Arzneimittel
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ES2401285T3 (es) 2004-12-16 2013-04-18 The Regents Of The University Of California Fármacos con el pulmón como diana
CN101132795B (zh) 2004-12-30 2011-09-21 梅迪弗股份公司 用于hiv治疗的化合物
JP2008538354A (ja) 2005-04-08 2008-10-23 キメリクス，インコーポレイテッド ウイルス感染症およびその他の内科疾患を治療するための化合物、組成物および方法
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US8993580B2 (en) 2008-03-14 2015-03-31 Intellikine Llc Benzothiazole kinase inhibitors and methods of use
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US9278135B2 (en) 2010-04-26 2016-03-08 Chimerix Inc. Methods of treating retroviral infections and related dosage regimes
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JP2013545749A (ja) 2010-11-10 2013-12-26 インフィニティー ファーマシューティカルズ， インコーポレイテッド 複素環化合物及びその使用
AU2012205669B2 (en) 2011-01-10 2015-08-20 Infinity Pharmaceuticals Inc. Processes for preparing isoquinolinones and solid forms of isoquinolinones
JP6130305B2 (ja) 2011-02-23 2017-05-17 インテリカイン， エルエルシー キナーゼ阻害剤の組み合わせおよびそれらの使用
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Also Published As

Publication number Publication date
DE59103595D1 (de) 1995-01-05
AU654670B2 (en) 1994-11-17
SK281826B6 (sk) 2001-08-06
CA2090024A1 (en) 1992-02-21
EP0545966A1 (de) 1993-06-16
SK9293A3 (en) 1993-07-07
FI104176B1 (fi) 1999-11-30
HK35597A (en) 1997-03-27
NO930587D0 (no) 1993-02-19
NO179710B (no) 1996-08-26
CN1032258C (zh) 1996-07-10
DE4026265A1 (de) 1992-02-27
FI104176B (fi) 1999-11-30
NO179710C (no) 1996-12-04
IE912930A1 (en) 1992-02-26
CA2090024C (en) 2000-05-02
WO1992003462A1 (de) 1992-03-05
NO930587L (no) 1993-02-19
ES2066461T3 (es) 1995-03-01
IE64374B1 (en) 1995-07-26
ATE114316T1 (de) 1994-12-15
DK0545966T3 (da) 1995-05-08
EP0545966B1 (de) 1994-11-23
PT98720B (pt) 1999-02-26
FI930753L (fi) 1993-02-19
US5756711A (en) 1998-05-26
CN1059149A (zh) 1992-03-04
AU8325191A (en) 1992-03-17
FI930753A0 (fi) 1993-02-19

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