PT98825A - Processo para a preparacao de uma suspensao aquosa de sal de aluminio de sulfatdo de sucralose sucralfato - Google Patents
Processo para a preparacao de uma suspensao aquosa de sal de aluminio de sulfatdo de sucralose sucralfatoInfo
- Publication number
- PT98825A PT98825A PT98825A PT9882591A PT98825A PT 98825 A PT98825 A PT 98825A PT 98825 A PT98825 A PT 98825A PT 9882591 A PT9882591 A PT 9882591A PT 98825 A PT98825 A PT 98825A
- Authority
- PT
- Portugal
- Prior art keywords
- sucralfate
- stock solution
- aqueous suspension
- powder
- sucrhalate
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000007900 aqueous suspension Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000004376 Sucralose Substances 0.000 title 1
- DIZPMCHEQGEION-UHFFFAOYSA-H aluminium sulfate (anhydrous) Chemical compound [Al+3].[Al+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O DIZPMCHEQGEION-UHFFFAOYSA-H 0.000 title 1
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 title 1
- 235000019408 sucralose Nutrition 0.000 title 1
- MNQYNQBOVCBZIQ-JQOFMKNESA-A sucralfate Chemical compound O[Al](O)OS(=O)(=O)O[C@@H]1[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](COS(=O)(=O)O[Al](O)O)O[C@H]1O[C@@]1(COS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)O1 MNQYNQBOVCBZIQ-JQOFMKNESA-A 0.000 abstract 5
- 229960004291 sucralfate Drugs 0.000 abstract 5
- 239000000843 powder Substances 0.000 abstract 4
- 239000011550 stock solution Substances 0.000 abstract 4
- 239000002245 particle Substances 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Colloid Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Detergent Compositions (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
- Supporting Of Heads In Record-Carrier Devices (AREA)
- Electrically Operated Instructional Devices (AREA)
- Pinball Game Machines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23230590 | 1990-08-31 | ||
| JP23616190 | 1990-09-06 | ||
| JP32144990 | 1990-11-26 | ||
| JP8252691 | 1991-04-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT98825A true PT98825A (pt) | 1992-07-31 |
| PT98825B PT98825B (pt) | 1999-02-26 |
Family
ID=27466711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98825A PT98825B (pt) | 1990-08-31 | 1991-08-30 | Processo para a preparacao de uma suspensao aquosa de sal de aluminio de sulfatdo de sucralose sucralfato |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5563258A (pt) |
| EP (1) | EP0549794B1 (pt) |
| KR (1) | KR100191189B1 (pt) |
| CN (1) | CN1049816C (pt) |
| AT (1) | ATE209498T1 (pt) |
| AU (1) | AU658576B2 (pt) |
| CA (1) | CA2090479C (pt) |
| DE (1) | DE69132837T2 (pt) |
| DK (1) | DK0549794T3 (pt) |
| ES (1) | ES2168251T3 (pt) |
| FI (1) | FI101856B1 (pt) |
| NO (1) | NO301691B1 (pt) |
| PT (1) | PT98825B (pt) |
| WO (1) | WO1992004030A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE213635T1 (de) * | 1994-04-26 | 2002-03-15 | Chugai Pharmaceutical Co Ltd | Verfahren für die herstellung schmelz-granulierte sucralfatzubereitung |
| CN101203248A (zh) * | 2005-06-21 | 2008-06-18 | 马林克罗特公司 | 光学成像造影剂 |
| FR2927808B1 (fr) * | 2008-02-26 | 2011-04-29 | Fabre Pierre Dermo Cosmetique | Gel de sucralfate sterilise |
| US10716802B2 (en) | 2013-03-15 | 2020-07-21 | The Brigham And Women's Hospital, Inc. | Compounds to modulate intestinal absorption of nutrients |
| WO2017053970A1 (en) | 2015-09-24 | 2017-03-30 | The Brigham And Women's Hospital, Inc. | Water-activated mucoadhesive compositions to reduce intestinal absorption of nutrients |
| KR101837104B1 (ko) * | 2017-04-14 | 2018-03-09 | 한국프라임제약주식회사 | 수크랄페이트 합성 방법 및 이에 의한 수크랄페이트 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3432489A (en) * | 1965-11-05 | 1969-03-11 | Chugai Pharmaceutical Co Ltd | Disaccharide polysulfate aluminium compound and method |
| JPS5978116A (ja) * | 1982-10-27 | 1984-05-04 | Chugai Pharmaceut Co Ltd | スクラルフェ−ト製剤 |
| JPS60222491A (ja) * | 1984-04-18 | 1985-11-07 | Chugai Pharmaceut Co Ltd | ペンタエリスリト−ル誘導体 |
| DE3430809A1 (de) * | 1984-08-22 | 1986-03-06 | Merck Patent Gmbh, 6100 Darmstadt | Sucralfat-suspension |
| DK164199C (da) * | 1986-05-16 | 1992-10-19 | Chugai Pharmaceutical Co Ltd | Sucralfatpraeparat til anvendelse paa oesophagus mucosa |
| IT1203901B (it) * | 1987-04-15 | 1989-02-23 | Lisapharma Spa | Composizioni farmaceutiche sotto forma di sospensioni stabili di sucralfato esenti da agenti sospendenti |
| DK505488D0 (da) * | 1987-12-21 | 1988-09-09 | Bar Shalom Daniel | Middel og anvendelse af samme |
| US4990610A (en) * | 1988-08-25 | 1991-02-05 | Applied Analytical Industries, Inc. | Method for preparing high potency sucralfate |
| US5084446A (en) * | 1988-08-25 | 1992-01-28 | Applied Analytical Industries, Inc. | Aluminum complex of polysulfonated sucrose |
| JPH04500996A (ja) * | 1988-11-03 | 1992-02-20 | ケーニッヒ,ラインハルト | 制御部を備えた制御可能駆動装置及びこのような駆動装置用シール |
| IL95642A0 (en) * | 1989-09-15 | 1991-06-30 | Pehrom Pharmaceutical Corp | Topical preparations for treatment of ulcers and other lesions |
-
1991
- 1991-08-22 AT AT91914664T patent/ATE209498T1/de not_active IP Right Cessation
- 1991-08-22 KR KR1019930700531A patent/KR100191189B1/ko not_active Expired - Lifetime
- 1991-08-22 DE DE69132837T patent/DE69132837T2/de not_active Expired - Lifetime
- 1991-08-22 EP EP91914664A patent/EP0549794B1/en not_active Expired - Lifetime
- 1991-08-22 ES ES91914664T patent/ES2168251T3/es not_active Expired - Lifetime
- 1991-08-22 AU AU83937/91A patent/AU658576B2/en not_active Expired
- 1991-08-22 WO PCT/JP1991/001114 patent/WO1992004030A1/ja not_active Ceased
- 1991-08-22 CA CA002090479A patent/CA2090479C/en not_active Expired - Lifetime
- 1991-08-22 DK DK91914664T patent/DK0549794T3/da active
- 1991-08-30 PT PT98825A patent/PT98825B/pt not_active IP Right Cessation
- 1991-08-31 CN CN91108635A patent/CN1049816C/zh not_active Expired - Lifetime
-
1993
- 1993-02-23 NO NO930623A patent/NO301691B1/no not_active IP Right Cessation
- 1993-02-25 FI FI930849A patent/FI101856B1/fi not_active IP Right Cessation
-
1995
- 1995-04-26 US US08/429,512 patent/US5563258A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NO930623L (no) | 1993-03-25 |
| AU658576B2 (en) | 1995-04-27 |
| DK0549794T3 (da) | 2002-02-11 |
| NO930623D0 (no) | 1993-02-23 |
| ES2168251T3 (es) | 2002-06-16 |
| CN1059844A (zh) | 1992-04-01 |
| KR100191189B1 (ko) | 1999-06-15 |
| CA2090479A1 (en) | 1992-03-01 |
| PT98825B (pt) | 1999-02-26 |
| CA2090479C (en) | 2002-01-15 |
| DE69132837D1 (de) | 2002-01-10 |
| ATE209498T1 (de) | 2001-12-15 |
| FI101856B (fi) | 1998-09-15 |
| FI930849L (fi) | 1993-02-25 |
| EP0549794A1 (en) | 1993-07-07 |
| AU8393791A (en) | 1992-03-30 |
| EP0549794A4 (en) | 1993-10-20 |
| EP0549794B1 (en) | 2001-11-28 |
| WO1992004030A1 (fr) | 1992-03-19 |
| FI101856B1 (fi) | 1998-09-15 |
| US5563258A (en) | 1996-10-08 |
| FI930849A0 (fi) | 1993-02-25 |
| DE69132837T2 (de) | 2002-04-11 |
| CN1049816C (zh) | 2000-03-01 |
| NO301691B1 (no) | 1997-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19920318 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19981102 |
|
| MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20131104 |