PT991654E - Novos derivados de 2-(iminometil)amino-fenilo sua preparacao sua aplicacao como medicamentos e composicoes farmaceuticas que os contem - Google Patents

Novos derivados de 2-(iminometil)amino-fenilo sua preparacao sua aplicacao como medicamentos e composicoes farmaceuticas que os contem

Info

Publication number
PT991654E
PT991654E PT98932205T PT98932205T PT991654E PT 991654 E PT991654 E PT 991654E PT 98932205 T PT98932205 T PT 98932205T PT 98932205 T PT98932205 T PT 98932205T PT 991654 E PT991654 E PT 991654E
Authority
PT
Portugal
Prior art keywords
iminomethyl
amino
preparation
application
phenyl
Prior art date
Application number
PT98932205T
Other languages
English (en)
Inventor
Jeremiah Harnett
Dennis Bigg
De Lassauniere Pierre Chabrier
Serge Auvin
Original Assignee
Sod Conseils Rech Applic
Ntifiques S C R A S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic, Ntifiques S C R A S filed Critical Sod Conseils Rech Applic
Publication of PT991654E publication Critical patent/PT991654E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D521/00—Heterocyclic compounds containing unspecified hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Pyrrole Compounds (AREA)
PT98932205T 1997-06-20 1998-06-15 Novos derivados de 2-(iminometil)amino-fenilo sua preparacao sua aplicacao como medicamentos e composicoes farmaceuticas que os contem PT991654E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9707701A FR2764889B1 (fr) 1997-06-20 1997-06-20 Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
PT991654E true PT991654E (pt) 2005-10-31

Family

ID=9508226

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98932205T PT991654E (pt) 1997-06-20 1998-06-15 Novos derivados de 2-(iminometil)amino-fenilo sua preparacao sua aplicacao como medicamentos e composicoes farmaceuticas que os contem

Country Status (28)

Country Link
EP (1) EP0991654B1 (pt)
JP (1) JP2002507965A (pt)
KR (2) KR100618478B1 (pt)
CN (1) CN1195762C (pt)
AR (1) AR012250A1 (pt)
AT (1) ATE297935T1 (pt)
AU (1) AU737964B2 (pt)
BR (1) BR9810197B1 (pt)
CA (1) CA2294809C (pt)
CZ (1) CZ299237B6 (pt)
DE (1) DE69830584T2 (pt)
DK (1) DK0991654T3 (pt)
ES (1) ES2244068T3 (pt)
FR (1) FR2764889B1 (pt)
HU (1) HUP0002425A3 (pt)
IL (1) IL133223A (pt)
MY (1) MY123193A (pt)
NO (1) NO315321B1 (pt)
NZ (1) NZ501656A (pt)
PL (1) PL191987B1 (pt)
PT (1) PT991654E (pt)
RU (1) RU2202543C2 (pt)
SK (1) SK286911B6 (pt)
TR (1) TR199903175T2 (pt)
TW (1) TW422842B (pt)
UA (1) UA70921C2 (pt)
WO (1) WO1998058934A1 (pt)
ZA (1) ZA985392B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9801990D0 (sv) 1998-06-04 1998-06-04 Astra Ab New 3-aryl propionic acid derivatives and analogs
AR019190A1 (es) * 1998-07-08 2001-12-26 Sod Conseils Rech Applic Derivados de 2-aminopiridinas, productos intermedios para su preparacion, medicamentos y composiciones farmaceuticas que los contienen y su uso para preparar medicamentos
AU5194999A (en) * 1998-08-07 2000-02-28 Takeda Chemical Industries Ltd. Benzothiepin derivatives, process for the preparation of the same and uses thereof
FR2783519B1 (fr) * 1998-09-23 2003-01-24 Sod Conseils Rech Applic Nouveaux derives d'amidines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant
FR2798127A1 (fr) * 1999-09-03 2001-03-09 Expansia Sa Nouveau procede de preparation d'amidines derivees de l'acide 6-hydroxy-2,5,7,8-tetramethylchrommane-2-carboxy- lique
FR2812546B1 (fr) * 2000-08-01 2008-11-21 Sod Conseils Rech Applic Derives d'heterocycles a 5 chainons, leur preparation et leur application a titre de medicaments
TWI283577B (en) * 1999-10-11 2007-07-11 Sod Conseils Rech Applic Pharmaceutical composition of imidazole derivatives acting as modulators of sodium channels and the use thereof
FR2799461B1 (fr) * 1999-10-11 2002-01-04 Sod Conseils Rech Applic Derives d'heterocycles a 5 chainons, leur preparation et leur application a titre de medicaments
RU2380362C2 (ru) * 1999-10-11 2010-01-27 Сосьете Де Консей Де Решерш З Производные пятичленных гетероциклов, способ их получения и их применение в качестве лекарственных средств
FR2801053B1 (fr) * 1999-11-16 2004-06-25 Sod Conseils Rech Applic Nouveaux derives d'amidines, leur preparation et leur application a titre de medicaments
SE9904677D0 (sv) * 1999-12-20 1999-12-20 Astra Ab Novel compounds
SE9904676D0 (sv) * 1999-12-20 1999-12-20 Astra Ab Novel compounds
GB0019006D0 (en) * 2000-08-04 2000-09-20 Astrazeneca Ab Novel compounds
WO2002020511A1 (en) * 2000-09-05 2002-03-14 Astrazeneca Ab Amidine derivatives which are inhibitors of nitric oxide synthase
TWI248438B (en) * 2001-04-10 2006-02-01 Sod Conseils Rech Applic Derivatives of heterocycles with 5 members, their preparation and their use as medicaments
AU2002314944B2 (en) * 2001-06-08 2008-03-06 Cytokine Pharmasciences, Inc. Isoxazoline compounds having MIF antagonist activity
HU228783B1 (en) * 2001-07-26 2013-05-28 Greenearth Cleaning Dry cleaning apparatus and method capable of utilizing a siloxane solvent
ES2378146T3 (es) * 2002-04-03 2012-04-09 Novartis Ag Derivados de 1,1-dioxo-1, 2,5-tiazolidina-3-ona sustituida como inhibidores de ptpasa 1B
FR2842808B1 (fr) * 2002-07-25 2004-09-10 Sod Conseils Rech Applic Nouveaux derives d'arylimidazoles, leur preparation et leurs applications therapeutiques
DE10233817A1 (de) * 2002-07-25 2004-02-12 Aventis Pharma Deutschland Gmbh Substituierte Diarylheterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US7141561B2 (en) 2002-07-25 2006-11-28 Sanofi-Aventis Deutschland Gmbh Substituted diaryl heterocycles, process for their preparation and their use as medicaments
CA2557166C (en) * 2004-03-26 2015-06-30 Cytokine Pharmasciences, Inc. Compounds, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor
WO2006022442A1 (ja) * 2004-08-24 2006-03-02 Santen Pharmaceutical Co., Ltd. ジヒドロオロテートデヒドロゲナーゼ阻害活性を有する新規複素環アミド誘導体
NZ561613A (en) * 2005-02-18 2010-12-24 Astrazeneca Ab Antibacterial piperidine derivatives
NZ560633A (en) 2005-03-11 2011-08-26 Neuprotect Pty Ltd Flavonoid compounds and uses thereof
CA2773038A1 (en) 2009-09-04 2011-03-10 P. Jeffrey Conn Mglur4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
US9051296B2 (en) 2009-11-16 2015-06-09 Raqualia Pharma Inc. Aryl carboxamide derivatives as TTX-S blockers
CN104662011B (zh) * 2012-07-12 2017-09-29 康尊知识产权公司 治疗线粒体疾病的色满衍生物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9127376D0 (en) * 1991-12-24 1992-02-19 Wellcome Found Amidino derivatives
US5807885A (en) * 1993-08-12 1998-09-15 Astra Aktiebolag Amidine derivatives with nitric oxide synthetase activities
WO1996001817A1 (en) * 1994-05-07 1996-01-25 Astra Aktiebolag Bicyclic amidine derivatives as inhibitors of nitric oxide synthetase

Also Published As

Publication number Publication date
DK0991654T3 (da) 2005-10-17
ES2244068T3 (es) 2005-12-01
KR100618478B1 (ko) 2006-09-01
UA70921C2 (uk) 2004-11-15
CN1195762C (zh) 2005-04-06
KR20010013983A (ko) 2001-02-26
ZA985392B (en) 1999-01-20
WO1998058934A1 (fr) 1998-12-30
SK286911B6 (sk) 2009-07-06
HUP0002425A1 (hu) 2001-11-28
MY123193A (en) 2006-05-31
CZ299237B6 (cs) 2008-05-28
EP0991654A1 (fr) 2000-04-12
TR199903175T2 (xx) 2000-04-21
EP0991654B1 (fr) 2005-06-15
TW422842B (en) 2001-02-21
NO996208D0 (no) 1999-12-15
AU8218998A (en) 1999-01-04
CA2294809A1 (fr) 1998-12-30
SK179699A3 (en) 2000-05-16
JP2002507965A (ja) 2002-03-12
NZ501656A (en) 2001-12-21
NO996208L (no) 2000-02-15
RU2202543C2 (ru) 2003-04-20
IL133223A0 (en) 2001-03-19
CN1264385A (zh) 2000-08-23
BR9810197A (pt) 2000-08-08
DE69830584T2 (de) 2006-03-16
DE69830584D1 (de) 2005-07-21
CA2294809C (fr) 2010-02-02
ATE297935T1 (de) 2005-07-15
KR100545946B1 (ko) 2006-01-26
AR012250A1 (es) 2000-09-27
KR20050098970A (ko) 2005-10-12
IL133223A (en) 2004-09-27
BR9810197B1 (pt) 2010-02-09
FR2764889B1 (fr) 2000-09-01
FR2764889A1 (fr) 1998-12-24
AU737964B2 (en) 2001-09-06
PL191987B1 (pl) 2006-07-31
HK1030218A1 (en) 2001-04-27
NO315321B1 (no) 2003-08-18
CZ459799A3 (cs) 2000-07-12
HUP0002425A3 (en) 2001-12-28
PL337499A1 (en) 2000-08-28

Similar Documents

Publication Publication Date Title
BR9808427A (pt) Produto, processo de preparação e utilização do mesmo e composição farmacêutica
UA70921C2 (uk) Похідні 2-(імінометил)амінофенілу, спосіб їх одержання (варіанти) та фармацевтична композиція, що містить ці сполуки
TR200200768T2 (tr) Yeni kuinüklidin türevleri ve bunu içeren ilaç bileşimleri
DK0994710T4 (da) Farmaceutiske præparater til oral indgivelse omfattende en benzylhydrylpiperazin og en cyclodextrin
HUP9800688A2 (hu) Gamma-ciklodextrin és retinol, ill. retinolszármazékok komplexei, eljárás ezek előállítására és ezeket tartalmazó kozmetikai és gyógyszerkészítmények
ES2144192T3 (es) Nuevos derivados de 1-fenil-2-dimetil-amino-metil-ciclohexan-1-ol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
BR0315296A (pt) Derivados do ciclohexanol espirocìclicos
BR9909565A (pt) Derivados bicìclicos do ácido hidroxâmico
BR0208338A (pt) Derivados de piridina
TR200001218T2 (tr) İkameli karboksamidotiazoller, bunların üretimi ve bunları içeren farmasötik bileşimler.
BR0210139A (pt) Composições farmacêuticas
DK0693924T3 (da) Fremgangsmåde til (in vivo)-levering af biologiske materialer og sammensætninger, der er egnede dertil
EE200200357A (et) Ravimaine suurenenud kontsentratsioone andvad farmatseutilised kompositsioonid
BR9911871B1 (pt) derivados de ácido fenoxiacético e composições farmacêuticas contendo os mesmos.
AR026227A1 (es) Composiciones farmaceuticas que contienen una droga antibiotico de fluoroquinolona y goma de xantano
PT90661A (pt) Processo para a preparacao de composicoes farmaceuticas contendo inibidores da enzima conversora de angiotensina e moduladores de canal de potassio
PT952975E (pt) Compostos bi-aromaticos ligados por um radical hetero-etinileno e composicoes farmaceuticas e cosmeticas que os contem
BR0308201A (pt) Derivados de quinolina
BR9802803A (pt) ação e composições farmacêuticas contendo os mesmos.
PT1001942E (pt) Poli-hidroxibutilpirazinas sua preparacao e medicamentos que as contem
PT1000067E (pt) Tiazolobenzo-heterociclos sua preparacao e medicamentos que os contem
NO20020914D0 (no) Alkoksy-substituerte benzimidazolforbindelser, preparater inneholdende slike samt anvendelser derav
DZ3163A1 (fr) Nouvelle substance pharmaceutique.
PT989994E (pt) Derivados de estreptograminas, a sua preparacao e as composicoes que os contem
BR0114459A (pt) Derivados substituìdos de 5-amino-1-penten-3-ol substituidos