PT99677A - Processo de preparacao de um polipeptido que se liga a gpiia-iiib de vectores de composicoes de anticorpos e processo de ligacao de celulas a um substrato - Google Patents
Processo de preparacao de um polipeptido que se liga a gpiia-iiib de vectores de composicoes de anticorpos e processo de ligacao de celulas a um substratoInfo
- Publication number
- PT99677A PT99677A PT99677A PT9967791A PT99677A PT 99677 A PT99677 A PT 99677A PT 99677 A PT99677 A PT 99677A PT 9967791 A PT9967791 A PT 9967791A PT 99677 A PT99677 A PT 99677A
- Authority
- PT
- Portugal
- Prior art keywords
- cells
- amino acid
- binding
- preparation
- polypeptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/56—Fibrin; Thrombin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/29—Polyamino acid or polypeptide with an uninterrupted series of peptide repeating units
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62066890A | 1990-12-03 | 1990-12-03 | |
| US72560091A | 1991-07-03 | 1991-07-03 | |
| US07/803,623 US5773574A (en) | 1990-12-03 | 1991-11-27 | Polypeptides for promoting cell attachment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT99677A true PT99677A (pt) | 1992-12-31 |
| PT99677B PT99677B (pt) | 1999-05-31 |
Family
ID=27417270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99677A PT99677B (pt) | 1990-12-03 | 1991-12-03 | Processo de preparacao de um polipeptido que se liga a gpiia-iiib de vectores de composicoes de anticorpos e processo de ligacao de celulas a um substrato |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US5773574A (pt) |
| AU (1) | AU9165991A (pt) |
| IE (1) | IE62855B1 (pt) |
| PT (1) | PT99677B (pt) |
| WO (1) | WO1992009200A1 (pt) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5492890A (en) * | 1990-12-03 | 1996-02-20 | The Scripps Research Institute | Polypeptides for promoting cell attachment |
| US5773574A (en) * | 1990-12-03 | 1998-06-30 | The Scripps Research Institute | Polypeptides for promoting cell attachment |
| WO1994013692A1 (en) * | 1992-12-10 | 1994-06-23 | Regents Of The University Of Minnesota | Polypeptides useful for treating inflammatory disorders |
| WO1995024873A1 (en) * | 1994-03-14 | 1995-09-21 | Cryolife, Inc. | Treated tissue for implantation and preparation methods |
| US6933366B2 (en) * | 1996-12-27 | 2005-08-23 | Tripep Ab | Specificity exchangers that redirect antibodies to bacterial adhesion receptors |
| US6040137A (en) * | 1995-04-27 | 2000-03-21 | Tripep Ab | Antigen/antibody specification exchanger |
| US6660842B1 (en) * | 1994-04-28 | 2003-12-09 | Tripep Ab | Ligand/receptor specificity exchangers that redirect antibodies to receptors on a pathogen |
| ES2327982T3 (es) * | 1996-11-21 | 2009-11-05 | The Regents Of The University Of Michigan | Inhibidores de la invasion para su utilizacion en la cicatrizacion de heridas y cancer. |
| US20030190740A1 (en) | 1998-10-13 | 2003-10-09 | The University Of Georgia Research Foundation, Inc | Stabilized bioactive peptides and methods of identification, synthesis, and use |
| JP2003502019A (ja) * | 1999-04-16 | 2003-01-21 | チルドレンズ メディカル センター コーポレーション | 接着調節ペプチドおよび使用のための方法 |
| EP2141243A3 (en) * | 2000-10-16 | 2010-01-27 | Brystol-Myers Squibb Company | Protein scaffolds for antibody mimics and other binding proteins |
| US7507412B2 (en) * | 2001-07-18 | 2009-03-24 | Merck Patent Gmbh | Glycoprotein VI fusion proteins |
| CA2478317A1 (en) * | 2002-03-04 | 2003-09-18 | Medimmune, Inc. | Methods of preventing or treating disorders by administering an integrin .alpha.v.beta.3 antagonist in combination with an hmg-coa reductase inhibitor or a bisphosphonate |
| WO2003075957A1 (en) * | 2002-03-04 | 2003-09-18 | Medimmune, Inc. | The prevention or treatment of cancer using integrin alphavbeta3 antagonists in combination with other agents |
| KR100885071B1 (ko) * | 2002-05-14 | 2009-02-25 | 재단법인서울대학교산학협력재단 | 세포에 부착하는 올리고펩타이드 |
| WO2004066956A2 (en) * | 2003-01-30 | 2004-08-12 | Medimmune, Inc. | Uses of integrin alphavbeta3 antagonists |
| EP2230249A3 (en) | 2003-02-06 | 2010-12-22 | ChronTech Pharma AB | Antigen/antibody or ligand/receptor glycosylated specificity exchangers |
| US7335359B2 (en) | 2003-02-06 | 2008-02-26 | Tripep Ab | Glycosylated specificity exchangers |
| US9198887B2 (en) | 2003-09-15 | 2015-12-01 | Nanopharmaceuticals Llc | Thyroid hormone analogs and methods of use |
| US8668926B1 (en) | 2003-09-15 | 2014-03-11 | Shaker A. Mousa | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof |
| CA2539288C (en) | 2003-09-15 | 2015-05-12 | Shaker A. Mousa | Thyroid hormone analogs and methods of use |
| US8071134B2 (en) * | 2003-09-15 | 2011-12-06 | Ordway Research Institute, Inc. | Thyroid hormone analogs and methods of use |
| WO2005068504A1 (ja) * | 2004-01-19 | 2005-07-28 | Medical And Biological Laboratories Co., Ltd. | 炎症性サイトカイン抑制剤 |
| US20090022806A1 (en) * | 2006-12-22 | 2009-01-22 | Mousa Shaker A | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists and formulations and uses thereof |
| US10130686B2 (en) | 2005-09-15 | 2018-11-20 | Nanopharmaceuticals Llc | Method and composition of thyroid hormone analogues and nanoformulations thereof for treating inflammatory disorders |
| US9220788B2 (en) * | 2009-06-17 | 2015-12-29 | Nanopharmaceuticals Llc | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof |
| US9498536B2 (en) | 2005-09-15 | 2016-11-22 | Nanopharmaceuticals Llc | Method and composition of thyroid hormone analogues and nanoformulations thereof for treating anti-inflammatory disorders |
| WO2007035612A2 (en) | 2005-09-16 | 2007-03-29 | Ordway Research Institute, Inc. | Polyphenol conjugates as rgd-binding compounds and methods of use |
| MX2009005466A (es) | 2006-11-22 | 2009-08-17 | Adnexus A Bristol Myers Sqibb | Terapeuticos dirigidos a base de proteinas manipuladas para receptores de tirosina cinasas, incluyendo receptor de factor de crecimiento tipo insulina-i. |
| EP2120913B1 (en) * | 2006-12-22 | 2015-01-21 | NanoPharmaceuticals LLC | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof |
| US8283169B1 (en) * | 2007-03-21 | 2012-10-09 | Allan Yang Wu | Differential gradient separation of cells |
| US20090092631A1 (en) * | 2007-03-26 | 2009-04-09 | Tripep Ab | Glycosylated specificity exchangers that induce an antibody dependent cellular cytotoxicity (adcc) response |
| AU2009213141A1 (en) | 2008-02-14 | 2009-08-20 | Bristol-Myers Squibb Company | Targeted therapeutics based on engineered proteins that bind EGFR |
| WO2009142773A2 (en) | 2008-05-22 | 2009-11-26 | Bristol-Myers Squibb Company | Multivalent fibronectin based scaffold domain proteins |
| TWI496582B (zh) | 2008-11-24 | 2015-08-21 | 必治妥美雅史谷比公司 | 雙重專一性之egfr/igfir結合分子 |
| US20100159021A1 (en) * | 2008-12-23 | 2010-06-24 | Paul Davis | Small Molecule Ligands of the Integrin RGD Recognition Site and Methods of Use |
| US9180107B2 (en) * | 2009-03-31 | 2015-11-10 | Nanopharmaceuticals Llc | Combination treatment of cancer with cetuximab and tetrac |
| TW201138808A (en) | 2010-05-03 | 2011-11-16 | Bristol Myers Squibb Co | Serum albumin binding molecules |
| JP6023703B2 (ja) | 2010-05-26 | 2016-11-09 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 改善された安定性を有するフィブロネクチンをベースとする足場タンパク質 |
| US8921516B2 (en) * | 2010-12-08 | 2014-12-30 | Corning Incorporated | Synthetic, defined fibronectin mimetic peptides and surfaces modified with the same |
| US8802240B2 (en) | 2011-01-06 | 2014-08-12 | Nanopharmaceuticals Llc | Uses of formulations of thyroid hormone analogs and nanoparticulate forms thereof to increase chemosensitivity and radiosensitivity in tumor or cancer cells |
| US9193779B2 (en) | 2012-10-26 | 2015-11-24 | Corning Incorporated | Recombinant human fibronectin fragment for cell culture |
| US10060934B2 (en) | 2013-11-18 | 2018-08-28 | Nanopharmaceuticals Llc | Methods for screening patients for resistance to angioinhibition, treatment and prophylaxis thereof |
| ES2736127T3 (es) | 2014-03-20 | 2019-12-26 | Bristol Myers Squibb Co | Dominios de tipo III de fibronectina de unión a seroalbúmina |
| CN108290941A (zh) | 2015-09-23 | 2018-07-17 | 百时美施贵宝公司 | 快解离速率的血清白蛋白结合性纤连蛋白iii型结构域 |
| US10201616B2 (en) | 2016-06-07 | 2019-02-12 | Nanopharmaceuticals, Llc | Non-cleavable polymer conjugated with αVβ3 integrin thyroid antagonists |
| WO2018052245A1 (ko) * | 2016-09-13 | 2018-03-22 | 윤원준 | 세포접착용 조성물 및 방법 |
| US10328043B1 (en) | 2018-04-11 | 2019-06-25 | Nanopharmaceuticals, Llc. | Composition and method for dual targeting in treatment of neuroendocrine tumors |
| US11351137B2 (en) | 2018-04-11 | 2022-06-07 | Nanopharmaceuticals Llc | Composition and method for dual targeting in treatment of neuroendocrine tumors |
| CN108794639B (zh) * | 2018-07-03 | 2020-11-20 | 广州澳特朗生物技术有限公司 | 一种重组纤连蛋白及其应用 |
| KR102013218B1 (ko) | 2019-02-01 | 2019-08-22 | 영남대학교 산학협력단 | 세포의 부착, 증식과 분화를 촉진하는 신규 펩티드 fnin2 및 이의 용도 |
| KR102053895B1 (ko) | 2019-02-01 | 2019-12-09 | 영남대학교 산학협력단 | 세포의 부착, 증식과 분화를 촉진하는 신규 펩티드 fnin3 및 이의 용도 |
| EP3938516A1 (en) * | 2019-03-15 | 2022-01-19 | Eligo Bioscience | Transcriptional control in prokaryotic cells using dna-binding repressors |
| KR102334899B1 (ko) | 2019-10-28 | 2021-12-03 | 영남대학교 산학협력단 | 암 세포의 증식을 억제하는 펩티드 fnin2 및 이의 용도 |
| US10961204B1 (en) | 2020-04-29 | 2021-03-30 | Nanopharmaceuticals Llc | Composition of scalable thyrointegrin antagonists with improved blood brain barrier penetration and retention into brain tumors |
| KR102304832B1 (ko) | 2020-08-12 | 2021-09-24 | 영남대학교 산학협력단 | 암 세포의 증식을 억제하는 펩티드 fnin3 및 이의 용도 |
| US11723888B2 (en) | 2021-12-09 | 2023-08-15 | Nanopharmaceuticals Llc | Polymer conjugated thyrointegrin antagonists |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4792525A (en) * | 1982-08-04 | 1988-12-20 | La Jolla Cancer Research Foundation | Tetrapeptide |
| US4578079A (en) * | 1982-08-04 | 1986-03-25 | La Jolla Cancer Research Foundation | Tetrapeptide |
| US4980279A (en) * | 1986-04-15 | 1990-12-25 | Scripps Clinic And Research Foundation | Cellular fibronectin: polypeptides, anti-polypeptide antibodies and assay methods |
| US5019646A (en) * | 1987-08-25 | 1991-05-28 | Regents Of The University Of Minnesota | Polypeptides with fibronectin activity |
| JPH0829098B2 (ja) * | 1988-01-05 | 1996-03-27 | 寳酒造株式会社 | 細胞接着活性ポリペプチド |
| US5196511A (en) * | 1989-12-01 | 1993-03-23 | The Scripps Research Institute | Peptides and antibodies that inhibit integrin-ligand binding |
| US5773574A (en) * | 1990-12-03 | 1998-06-30 | The Scripps Research Institute | Polypeptides for promoting cell attachment |
-
1991
- 1991-11-27 US US07/803,623 patent/US5773574A/en not_active Expired - Lifetime
- 1991-12-02 IE IE418491A patent/IE62855B1/en not_active IP Right Cessation
- 1991-12-03 AU AU91659/91A patent/AU9165991A/en not_active Abandoned
- 1991-12-03 PT PT99677A patent/PT99677B/pt not_active IP Right Cessation
- 1991-12-03 WO PCT/US1991/009029 patent/WO1992009200A1/en not_active Ceased
-
1997
- 1997-02-25 US US08/806,084 patent/US5843774A/en not_active Expired - Lifetime
-
1998
- 1998-12-01 US US09/201,970 patent/US6316412B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IE62855B1 (en) | 1995-03-08 |
| IE914184A1 (en) | 1992-06-03 |
| PT99677B (pt) | 1999-05-31 |
| AU9165991A (en) | 1992-06-25 |
| US6316412B1 (en) | 2001-11-13 |
| US5773574A (en) | 1998-06-30 |
| US5843774A (en) | 1998-12-01 |
| WO1992009200A1 (en) | 1992-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19920814 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19990210 |
|
| MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20140210 |