RO62762A - Procede pour la preparation des(1,5a)-pyrimidines 3,5,7-tri-substitues - Google Patents

Procede pour la preparation des(1,5a)-pyrimidines 3,5,7-tri-substitues

Info

Publication number: RO62762A
Authority: RO; Romania
Prior art keywords: pyrimidines; tri; substituted; preparation
Prior art date: 1971-12-09

Application number

RO7200073093A

Other languages

English (en)

Romanian (ro)

Inventor

Roland K Robins

Darrel E O'brien

Thomas Novinson

Robert H Springer

Original Assignee

Icn Pharmaceutical Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-12-09

Filing date

1972-12-09

Publication date

1978-05-15

1972-04-20 Priority claimed from US245870A external-priority patent/US3925385A/en

1972-12-09 Application filed by Icn Pharmaceutical Inc filed Critical Icn Pharmaceutical Inc

1978-05-15 Publication of RO62762A publication Critical patent/RO62762A/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

RO7200073093A 1971-12-09 1972-12-09 Procede pour la preparation des(1,5a)-pyrimidines 3,5,7-tri-substitues RO62762A (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US20653871A	1971-12-09	1971-12-09
US245870A US3925385A (en)	1972-04-20	1972-04-20	6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines
US27346572A	1972-07-20	1972-07-20
US29984072A	1972-10-24	1972-10-24

Publications (1)

Publication Number	Publication Date
RO62762A true RO62762A (fr)	1978-05-15

Family

ID=27498614

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
RO7200073093A RO62762A (fr)	1971-12-09	1972-12-09	Procede pour la preparation des(1,5a)-pyrimidines 3,5,7-tri-substitues

Country Status (15)

Country	Link
JP (1)	JPS4864097A (fr)
BE (1)	BE792533A (fr)
BG (1)	BG22401A3 (fr)
CH (1)	CH603652A5 (fr)
DD (1)	DD104530A5 (fr)
DE (1)	DE2257547A1 (fr)
GB (1)	GB1412017A (fr)
HU (1)	HU168530B (fr)
IE (1)	IE37189B1 (fr)
IL (1)	IL40895A (fr)
LU (1)	LU66597A1 (fr)
NL (1)	NL7216539A (fr)
NO (1)	NO137012C (fr)
RO (1)	RO62762A (fr)
SE (1)	SE398751B (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4281000A (en) *	1979-07-09	1981-07-28	American Cyanamid Company	Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents
AU557300B2 (en) *	1982-03-16	1986-12-18	Farmitalia Carlo Erba S.P.A.	Substituted 1h-pyrazolo(1,5-alpha)pyrimidines and processes for their preparation
ZA831407B (en) *	1982-03-25	1983-11-30	Erba Farmitalia	Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation
NZ208554A (en) *	1983-06-23	1987-06-30	American Cyanamid Co	(aryl and heteroaryl)-(7-(aryl and heteroaryl)-pyrazolo (1,5-a) pyrimidin-3-yl)-methanone derivatives and pharmaceutical compositions
DE3533050A1 (de) *	1985-09-17	1987-03-26	Basf Ag	7-amino-azolo(1,5-a)pyrimidine, verfahren zu ihrer herstellung und diese enthaltende fungizide, bzw. deren verwendung als fungizide
CA1330079C (fr) *	1988-10-13	1994-06-07	Michihiko Tsujitani	Derive pyrrolo-(3,2-e)pyrazolo(1,5-a)pyrimidine et medicament en contenant
EP0591528B1 (fr) *	1991-04-22	1998-12-23	Otsuka Pharmaceutical Factory, Inc.	DERIVE DE PYRAZOLO[1,5-a]PYRIMIDINE ET AGENT ANTI-INFLAMMATOIRECONTENANT CE DERIVE
DE4333705C2 (de) *	1993-10-02	2003-10-30	Guenter Ege	Arylmethylsubstituierte Pyrazolo-azine, insbesondere 3-Arylmethylpyrazolo[1,5-a]pyrimidine und Verfahren zur Herstellung von 8-Arylmethyl-pyrazolo[5,1-c][1,2,4]triazinen
EP0714898B1 (fr) *	1994-06-21	2001-11-14	Otsuka Pharmaceutical Factory, Inc.	DERIVE DE PYRAZOLO [1,5-a]PYRIMIDINE
WO1997011946A1 (fr) *	1995-09-28	1997-04-03	Otsuka Pharmaceutical Factory, Inc.	Analgesiques
FR2771631B1 (fr)	1997-12-03	2001-02-02	Oreal	Compositions de teinture des fibres keratiniques contenant des 3-amino pyrazolo-[1,5-a]-pyrimidines, procede de teinture, nouvelles 3-amino pyrazolo- [1,5-a]-pyrimidines et leur procede de preparation
US7161003B1 (en) *	2002-09-04	2007-01-09	Schering Corporation	Pyrazolopyrimidines as cyclin dependent kinase inhibitors
EP1537116B1 (fr) *	2002-09-04	2010-06-02	Schering Corporation	Pyrazolopyrimidines utilisable pour le traitement des maladies cancereuses
US7119200B2 (en) *	2002-09-04	2006-10-10	Schering Corporation	Pyrazolopyrimidines as cyclin dependent kinase inhibitors
TWI252851B (en) *	2003-07-24	2006-04-11	Ferrer Int	7-substituted 3-nitro-pyrazolo[1,5-a]pyrimidines and compositions and methods related thereto
ES2222813B1 (es) *	2003-07-24	2005-12-16	Ferrer Internacional, S.A.	N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados.
SG11201506764WA (en)	2013-04-25	2015-09-29	Beigene Ltd	Fused heterocyclic compounds as protein kinase inhibitors
JP6623353B2 (ja)	2013-09-13	2019-12-25	ベイジーンスウィッツァーランドゲーエムベーハー	抗ｐｄ−１抗体並びにその治療及び診断のための使用
KR102003754B1 (ko)	2014-07-03	2019-07-25	베이진 엘티디	Pd-l1 항체와 이를 이용한 치료 및 진단
NZ749997A (en)	2016-07-05	2022-11-25	Beigene Ltd	Combination of a pd-l antagonist and a raf inhibitor for treating cancer
KR102604975B1 (ko)	2016-08-16	2023-11-24	베이진 스위찰랜드 게엠베하	(s)-7-(1-아크릴로일피페리딘-4-일)-2-(4-페녹시페닐)-4,5,6,7-테트라-하이드로피라졸로 [1,5-a] 피리미딘-3-카르복스아미드의 제조 및 그 용도
EP3500299B1 (fr)	2016-08-19	2023-12-13	BeiGene Switzerland GmbH	Combinaison de zanubrutinib avec un anticorps anti-cd20 ou anti-pd-1 pour l'utilisation dans le traitement du cancer
WO2018137681A1 (fr)	2017-01-25	2018-08-02	Beigene, Ltd.	Formes cristallines de (s) -7- (1- (but-2-ynoyl) pipéridin-4-yl) -2- (4-phénoxyphényl) -4, 5, 6, 7-tétrahy dropyrazolo [1, 5-a] pyrimidine-3-carboxamide, préparation et utilisations associées
KR102757960B1 (ko)	2017-06-26	2025-01-22	베이진 엘티디	간세포암(hepatocellular carcinoma: HCC)에 대한 면역 치료
CN110997677A (zh)	2017-08-12	2020-04-10	百济神州有限公司	具有改进的双重选择性的Btk抑制剂
WO2019108795A1 (fr)	2017-11-29	2019-06-06	Beigene Switzerland Gmbh	Traitement de lymphomes à cellules b indolentes ou agressives au moyen d'une combinaison comprenant des inhibiteurs de btk
US20220249491A1 (en)	2019-06-10	2022-08-11	Beigene Switzerland Gmbh	Oral solid tablet comprising bruton's tyrosine kinase inhibitor and preparation method therefor
US11786531B1 (en)	2022-06-08	2023-10-17	Beigene Switzerland Gmbh	Methods of treating B-cell proliferative disorder

0
- BE BE792533D patent/BE792533A/fr unknown
1972
- 1972-11-21 IE IE1612/72A patent/IE37189B1/xx unknown
- 1972-11-22 IL IL40895A patent/IL40895A/en unknown
- 1972-11-23 DE DE2257547A patent/DE2257547A1/de active Pending
- 1972-12-01 GB GB5558772A patent/GB1412017A/en not_active Expired
- 1972-12-05 SE SE7215829A patent/SE398751B/xx unknown
- 1972-12-05 LU LU66597A patent/LU66597A1/xx unknown
- 1972-12-06 NL NL7216539A patent/NL7216539A/xx not_active Application Discontinuation
- 1972-12-06 CH CH1775172A patent/CH603652A5/xx not_active IP Right Cessation
- 1972-12-06 NO NO4476/72A patent/NO137012C/no unknown
- 1972-12-07 DD DD167370A patent/DD104530A5/xx unknown
- 1972-12-08 HU HUIE548A patent/HU168530B/hu unknown
- 1972-12-09 JP JP47123877A patent/JPS4864097A/ja active Pending
- 1972-12-09 RO RO7200073093A patent/RO62762A/fr unknown
- 1972-12-09 BG BG022071A patent/BG22401A3/xx unknown

Also Published As

Publication number	Publication date
IL40895A (en)	1976-12-31
NL7216539A (fr)	1973-06-13
IE37189L (en)	1973-06-09
IL40895A0 (en)	1973-01-30
JPS4864097A (fr)	1973-09-05
NO137012B (no)	1977-09-05
DD104530A5 (fr)	1974-03-12
BE792533A (fr)	1973-06-08
HU168530B (fr)	1976-05-28
IE37189B1 (en)	1977-05-25
GB1412017A (en)	1975-10-29
NO137012C (no)	1977-12-14
BG22401A3 (bg)	1977-02-20
SE398751B (sv)	1978-01-16
LU66597A1 (fr)	1973-03-15
DE2257547A1 (de)	1973-06-14
CH603652A5 (fr)	1978-08-31

Publication	Publication Date	Title
RO62435A (fr)	1978-03-15	Procede pour la preparation des 1,2,4-triazolenucleosides
RO62762A (fr)	1978-05-15	Procede pour la preparation des(1,5a)-pyrimidines 3,5,7-tri-substitues
BE792326A (fr)	1973-03-30	Procede pour la preparation d'halogenohydrines
RO67478A (fr)	1980-03-15	Procede pour la preparation des pleuromutillines
RO62428A (fr)	1978-01-15	Procede pour la preparation des thyeno-(3,2-d)-pyrimidines
RO62861A (fr)	1977-11-15	Procede pour la preparation des di-n-oxydes-(1,4)-benzo-1,2,4-triazines
RO70438A (fr)	1981-04-30	Procede pour la preparation des pyrrol-2-carboxamides substitus
RO62694A (fr)	1978-05-15	Procede pour la preparation des 3-methylencephalosporines
RO63551A (fr)	1978-07-15	Procede pour la preparation des thieno-(3,2-d)-pyrimidines
RO64269A (fr)	1979-05-15	Procede pour la preparation des izoxazole-(5,4-d)-pirymidines
RO62699A (fr)	1978-03-15	Procede pour la preparation des 3-benzylpyridines subst
BE807434A (fr)	1974-05-16	Procede pour la preparation de 3,6-dihalo-diphenyl-alcanes
RO63031A (fr)	1978-05-15	Procede pour la preparation des pyrido-(3,2-d)-pyrimidi
CH550187A (fr)	1974-06-14	Procede de preparation de l'eburnamonine.
CH549579A (fr)	1974-05-31	Procede pour la preparation de nouvelles hydroxy-pyrimidines.
CH553178A (fr)	1974-08-30	Procede pour la preparation de la 3-hydroxy-2-alcoyl4-pyrone.
BE790056A (fr)	1973-04-13	Procede de preparation de 1, 1'-dianthraquinonyles
RO62512A (fr)	1978-02-15	Procede pour la preparation des thiazolo-(5,4-d)-pyrimidines
RO62312A (fr)	1977-12-15	Procede pour la preparation des 6-aza-3h-1,4-benzodiazepines
RO62467A (fr)	1977-11-15	Procede pour la preparation des 1-hydrocarbyl-3,4,5-tribrompyrazoles substitues
BE790055A (fr)	1973-04-13	Procede de preparation de 1,1'-dianthraquinonyles
RO64143A (fr)	1978-10-15	Procede pour la preparation des 5-alkyle-5 aralcolxy-1,3-dioxanes
RO62390A (fr)	1978-02-15	Procede pour la preparation des composes acylpropandiole-(1,3-)-phosphates de quoline
BE796204A (fr)	1973-09-03	Procede pour la preparation de 3,4,5,6,7,8-hexahydrocoumarine
BE761876A (fr)	1971-07-01	Procede pour la preparation de 1, 1' - peroxydicyclohexylamine