RU2012135677A - Способы и варианты применения, относящиеся к идентификации соединения, влияющего на боль, а также способы диагностики алгезии - Google Patents
Способы и варианты применения, относящиеся к идентификации соединения, влияющего на боль, а также способы диагностики алгезии Download PDFInfo
- Publication number
- RU2012135677A RU2012135677A RU2012135677/10A RU2012135677A RU2012135677A RU 2012135677 A RU2012135677 A RU 2012135677A RU 2012135677/10 A RU2012135677/10 A RU 2012135677/10A RU 2012135677 A RU2012135677 A RU 2012135677A RU 2012135677 A RU2012135677 A RU 2012135677A
- Authority
- RU
- Russia
- Prior art keywords
- compound
- pain
- car3
- test
- test system
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 47
- 208000002193 Pain Diseases 0.000 title claims abstract 24
- 238000000034 method Methods 0.000 title claims abstract 20
- 101000760630 Homo sapiens Carbonic anhydrase 3 Proteins 0.000 claims abstract 26
- 102100024650 Carbonic anhydrase 3 Human genes 0.000 claims abstract 14
- 230000000694 effects Effects 0.000 claims abstract 8
- 230000001413 cellular effect Effects 0.000 claims abstract 4
- 102000039446 nucleic acids Human genes 0.000 claims abstract 4
- 108020004707 nucleic acids Proteins 0.000 claims abstract 4
- 150000007523 nucleic acids Chemical class 0.000 claims abstract 4
- 230000008054 signal transmission Effects 0.000 claims 6
- 230000037361 pathway Effects 0.000 claims 2
- 208000004296 neuralgia Diseases 0.000 claims 1
- 208000021722 neuropathic pain Diseases 0.000 claims 1
- 230000019491 signal transduction Effects 0.000 abstract 4
- 101150096316 5 gene Proteins 0.000 abstract 1
- 101150039504 6 gene Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2842—Pain, e.g. neuropathic pain, psychogenic pain
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10305067.0 | 2010-01-21 | ||
| EP10305067A EP2348128A1 (de) | 2010-01-21 | 2010-01-21 | Verfahren und Verwendungen im Zusammenhang mit der Identifizierung einer am Schmerz beteiligten Verbindung sowie Verfahren zur Diagnose von Algesie |
| PCT/EP2011/050771 WO2012052189A1 (en) | 2010-01-21 | 2011-01-20 | Methods and uses relating to the identification of compound involved in pain as well as methods of diagnosing algesia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2012135677A true RU2012135677A (ru) | 2014-02-27 |
Family
ID=42112157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012135677/10A RU2012135677A (ru) | 2010-01-21 | 2011-01-20 | Способы и варианты применения, относящиеся к идентификации соединения, влияющего на боль, а также способы диагностики алгезии |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20130157880A1 (de) |
| EP (2) | EP2348128A1 (de) |
| JP (1) | JP2013531968A (de) |
| KR (1) | KR20120127464A (de) |
| CN (1) | CN102803513A (de) |
| AU (1) | AU2011317791A1 (de) |
| BR (1) | BR112012018122A2 (de) |
| CA (1) | CA2787463A1 (de) |
| MX (1) | MX2012008537A (de) |
| RU (1) | RU2012135677A (de) |
| SG (1) | SG182653A1 (de) |
| WO (1) | WO2012052189A1 (de) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI963989L (fi) | 1996-10-04 | 1998-04-05 | Wallac Oy | Homogeenisiä määritysmenetelmiä, jotka perustuvat luminesenssienergiasiirtoon |
| GB2377940A (en) * | 2001-07-27 | 2003-01-29 | Warner Lambert Co | Identification and use of molecules implicated in pain |
| AU2002324700A1 (en) * | 2001-08-14 | 2003-03-03 | Bayer Ag | Nucleic acid and amino acid sequences involved in pain |
| US20040044181A1 (en) * | 2001-08-31 | 2004-03-04 | Tang Y. Tom | Novel nucleic acids and polypeptides |
| EP1336661A1 (de) * | 2002-02-14 | 2003-08-20 | Biofrontera Pharmaceuticals AG | Diverse Gene, die für die Charakterisierung, Diagnose und Beeinflussing neuropathischer Schmerzen relevant sind |
| US20030216341A1 (en) * | 2002-02-14 | 2003-11-20 | Hermann Lubbert | Multiple genes relevant for the characterization, diagnosis, and manipulation of neuropathic pain |
| WO2005014849A2 (en) * | 2003-07-03 | 2005-02-17 | Euro-Celtique, S.A. | Genes associated with responses to neuropathic pain |
| WO2005043973A2 (en) * | 2003-10-28 | 2005-05-19 | Janssen Pharmaceutica Nv | Assay systems and methods for detecting molecules that interact with sk2 channels |
| US20060084066A1 (en) * | 2004-02-20 | 2006-04-20 | Sah Dinah W Y | Surrogate markers of neuropathic pain |
| EP2749571A3 (de) * | 2006-01-10 | 2014-08-13 | ZymoGenetics, Inc. | Verfahren zur Behandlung von Schmerzen und Entzündungen in Nervengewebe mithilfe von IL-31RA- und OSMRb-Antagonisten |
-
2010
- 2010-01-21 EP EP10305067A patent/EP2348128A1/de not_active Ceased
-
2011
- 2011-01-20 WO PCT/EP2011/050771 patent/WO2012052189A1/en not_active Ceased
- 2011-01-20 EP EP11700561A patent/EP2526203A1/de not_active Withdrawn
- 2011-01-20 AU AU2011317791A patent/AU2011317791A1/en not_active Abandoned
- 2011-01-20 CA CA2787463A patent/CA2787463A1/en not_active Abandoned
- 2011-01-20 BR BR112012018122A patent/BR112012018122A2/pt not_active IP Right Cessation
- 2011-01-20 CN CN2011800152634A patent/CN102803513A/zh active Pending
- 2011-01-20 US US13/521,535 patent/US20130157880A1/en not_active Abandoned
- 2011-01-20 MX MX2012008537A patent/MX2012008537A/es not_active Application Discontinuation
- 2011-01-20 JP JP2012556420A patent/JP2013531968A/ja not_active Abandoned
- 2011-01-20 RU RU2012135677/10A patent/RU2012135677A/ru not_active Application Discontinuation
- 2011-01-20 SG SG2012054052A patent/SG182653A1/en unknown
- 2011-01-20 KR KR1020127021754A patent/KR20120127464A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP2348128A1 (de) | 2011-07-27 |
| AU2011317791A8 (en) | 2013-11-28 |
| CA2787463A1 (en) | 2012-04-26 |
| BR112012018122A2 (pt) | 2017-01-10 |
| WO2012052189A8 (en) | 2012-08-16 |
| WO2012052189A1 (en) | 2012-04-26 |
| EP2526203A1 (de) | 2012-11-28 |
| KR20120127464A (ko) | 2012-11-21 |
| AU2011317791A1 (en) | 2012-08-09 |
| CN102803513A (zh) | 2012-11-28 |
| SG182653A1 (en) | 2012-08-30 |
| US20130157880A1 (en) | 2013-06-20 |
| JP2013531968A (ja) | 2013-08-15 |
| MX2012008537A (es) | 2012-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20150602 |