RU2640046C2 - Производные типа азаиндазола или диазаиндазола для лечения боли - Google Patents

Производные типа азаиндазола или диазаиндазола для лечения боли Download PDF

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Publication number: RU2640046C2
Authority: RU; Russia
Prior art keywords: arom; pain; mmol; group; added
Prior art date: 2012-07-27

Application number

RU2015106434A

Other languages

English (en)

Russian (ru)

Other versions

RU2015106434A (ru

Inventor

Пьер СОКОЛОФФ

Фредерик КАШУ

Original Assignee

Пьер Фабр Медикамент

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-07-27

Filing date

2013-07-29

Publication date

2017-12-26

2013-07-29 Application filed by Пьер Фабр Медикамент filed Critical Пьер Фабр Медикамент

2016-09-20 Publication of RU2015106434A publication Critical patent/RU2015106434A/ru

2017-12-26 Application granted granted Critical

2017-12-26 Publication of RU2640046C2 publication Critical patent/RU2640046C2/ru

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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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Health & Medical Sciences (AREA)
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Pharmacology & Pharmacy (AREA)
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Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
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Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
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Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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RU2015106434A 2012-07-27 2013-07-29 Производные типа азаиндазола или диазаиндазола для лечения боли RU2640046C2 (ru)

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EP12305922.2A EP2689778A1 (en)	2012-07-27	2012-07-27	Derivatives of azaindoles or diazaindoles for treating pain
EP12305922.2		2012-07-27
PCT/EP2013/065907 WO2014016433A1 (en)	2012-07-27	2013-07-29	Derivatives of azaindazole or diazaindazole type for treating pain

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EP (2)	EP2689778A1 (2)
JP (2)	JP6456823B2 (2)
KR (1)	KR102120505B1 (2)
CN (1)	CN104684554B (2)
AU (1)	AU2013294920B2 (2)
BR (1)	BR112015001502B1 (2)
CA (1)	CA2879595C (2)
CY (1)	CY1118478T1 (2)
DK (1)	DK2877177T3 (2)
ES (1)	ES2612349T3 (2)
HR (1)	HRP20170104T1 (2)
HU (1)	HUE032919T2 (2)
IL (1)	IL236917A (2)
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MX (1)	MX363605B (2)
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NZ (1)	NZ705253A (2)
PL (1)	PL2877177T3 (2)
PT (1)	PT2877177T (2)
RS (1)	RS55646B1 (2)
RU (1)	RU2640046C2 (2)
SI (1)	SI2877177T1 (2)
TN (1)	TN2015000034A1 (2)
UA (1)	UA116107C2 (2)
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RU2811975C1 (ru) *	2020-05-15	2024-01-19	СиЭсПиСи ЧЖУНЦИ ФАРМАСЬЮТИКАЛ ТЕКНОЛОДЖИ (ШИЦЗЯЧЖУАН) КО., ЛТД.	Конденсированное аза-гетероциклическое амидное соединение и его применение

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JP6732855B2 (ja)	2020-07-29
DK2877177T3 (en)	2017-02-06
MX363605B (es)	2019-03-26
US9381195B2 (en)	2016-07-05
IL236917A (en)	2016-11-30
MA37866B1 (fr)	2016-12-30
KR102120505B1 (ko)	2020-06-08
CY1118478T1 (el)	2017-07-12
US20150190394A1 (en)	2015-07-09
SI2877177T1 (sl)	2017-02-28
PT2877177T (pt)	2017-02-06
JP2015522650A (ja)	2015-08-06
BR112015001502B1 (pt)	2023-03-07
EP2877177A1 (en)	2015-06-03
LT2877177T (lt)	2017-01-25
BR112015001502A2 (pt)	2017-07-04
ZA201501209B (en)	2016-03-30
JP6456823B2 (ja)	2019-01-23
EP2877177B1 (en)	2016-10-26
CN104684554A (zh)	2015-06-03
HUE032919T2 (hu)	2017-11-28
AU2013294920A1 (en)	2015-03-12
PL2877177T3 (pl)	2017-04-28
AU2013294920B2 (en)	2017-08-24
TN2015000034A1 (en)	2016-06-29
CN104684554B (zh)	2017-05-10
NZ705253A (en)	2017-05-26
MY183398A (en)	2021-02-18
EP2689778A1 (en)	2014-01-29
JP2019031542A (ja)	2019-02-28
HK1207302A1 (en)	2016-01-29
MA37866A1 (fr)	2016-05-31
CA2879595A1 (en)	2014-01-30
RS55646B1 (sr)	2017-06-30
KR20150038295A (ko)	2015-04-08
WO2014016433A1 (en)	2014-01-30
HRP20170104T1 (hr)	2017-03-24
ES2612349T3 (es)	2017-05-16
MX2015001009A (es)	2015-06-04
CA2879595C (en)	2020-07-28
RU2015106434A (ru)	2016-09-20
UA116107C2 (uk)	2018-02-12

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