RU2666601C2 - Стабилизирующая композиция для биологических материалов - Google Patents

Стабилизирующая композиция для биологических материалов Download PDF

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RU2666601C2
RU2666601C2 RU2014136089A RU2014136089A RU2666601C2 RU 2666601 C2 RU2666601 C2 RU 2666601C2 RU 2014136089 A RU2014136089 A RU 2014136089A RU 2014136089 A RU2014136089 A RU 2014136089A RU 2666601 C2 RU2666601 C2 RU 2666601C2
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composition
protein
dry
acid
drying
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RU2014136089A
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RU2014136089A (ru
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Моти ХАРЕЛ
Кён ТАН
Триша РАЙС
Кимберли ДЖЕННИНГС
Брайан КАРПЕНТЕР
Роджер ДРЮС
Элизабет РЭДИТСИС
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Эдванст Бионутришн Корп.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P30/00—Shaping or working of foodstuffs characterised by the process or apparatus
    • A23P30/30—Puffing or expanding
    • A23P30/32—Puffing or expanding by pressure release, e.g. explosion puffing; by vacuum treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Inorganic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
RU2014136089A 2012-03-23 2013-03-22 Стабилизирующая композиция для биологических материалов RU2666601C2 (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261614994P 2012-03-23 2012-03-23
US61/614,994 2012-03-23
US201261642094P 2012-05-03 2012-05-03
US61/642,094 2012-05-03
US201261646337P 2012-05-13 2012-05-13
US61/646,337 2012-05-13
PCT/US2013/033505 WO2013142792A1 (en) 2012-03-23 2013-03-22 Stabilizing composition for biological materials

Publications (2)

Publication Number Publication Date
RU2014136089A RU2014136089A (ru) 2016-05-20
RU2666601C2 true RU2666601C2 (ru) 2018-09-11

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EP (1) EP2827905B1 (2)
JP (1) JP6229188B2 (2)
KR (1) KR102062645B1 (2)
CN (2) CN104244985A (2)
AR (1) AR093204A1 (2)
AU (1) AU2013234931B2 (2)
BR (1) BR112014023234B1 (2)
CA (1) CA2866889C (2)
CL (1) CL2014002506A1 (2)
ES (1) ES3016483T3 (2)
IN (1) IN2014DN08599A (2)
MX (1) MX356072B (2)
MY (1) MY178686A (2)
NZ (1) NZ628912A (2)
PH (1) PH12014502092B1 (2)
RU (1) RU2666601C2 (2)
SG (1) SG11201405478VA (2)
WO (1) WO2013142792A1 (2)

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RU2736064C1 (ru) * 2020-04-03 2020-11-11 Федеральное государственное бюджетное учреждение "48 Центральный научно-исследовательский институт" Министерства обороны Российской Федерации Защитная среда для стабилизации клеток возбудителя туляремии в процессе приготовления и хранения сухих препаратов
RU2806114C2 (ru) * 2022-04-21 2023-10-26 Общество С Ограниченной Ответственностью "Кинетик-Фарм" Средство для интравагинальной доставки активного компонента, способ получения и применения средства
WO2023204734A1 (ru) * 2022-04-21 2023-10-26 Общество С Ограниченной Ответственностью "Кинетик-Фарм" Средство для интравагинальной доставки активного компонента, способ получения и применения средства

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US20140255583A1 (en) * 2013-03-06 2014-09-11 Sunny Delight Beverages Company Protein suspension as a beverage opacifier system
BR112016008993B1 (pt) 2013-10-25 2021-08-31 Nch Corporation Composição probiótica para tratar animais, plantas, ou camas para animais, sistema para administrar uma composição probiótica, e, método para aumentar populações bacterianas benéficas nos tratos gastrointestinais de animais
US10766799B2 (en) 2014-05-23 2020-09-08 Nch Corporation Method for improving quality of aquaculture pond water using a nutrient germinant composition and spore incubation method
RU2722036C2 (ru) * 2015-02-11 2020-05-26 Превтек Майкробиа Инк. Усовершенствованная сухая матрица для встраивания жизнеспособных escherichia coli, способ ее получения и ее использования
US12558395B2 (en) 2015-07-29 2026-02-24 Advanced Bionutrition Corp. Stable dry probiotic compositions for special dietary uses
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AU2016365214B2 (en) * 2015-12-04 2021-02-25 Advanced Bionutrition Corp. Stable dry compositions having no or little sugars
HUE047606T2 (hu) * 2015-12-18 2020-05-28 Nestle Sa Hidratálás állatok részére
FR3045384B1 (fr) * 2015-12-18 2020-02-07 Institut National De La Recherche Agronomique Composition lyophilisee pour la conservation de microbiote dans son ecosysteme
CN105504050A (zh) * 2016-03-03 2016-04-20 河南欧普生物科技有限公司 一种抗安卡拉病毒鸡卵黄抗体的制备方法
US12097226B2 (en) 2016-04-05 2024-09-24 Nch Corporation System and method for using a single-serve nutrient spore composition for small scale farm applications
CA3019732A1 (en) 2016-04-05 2017-10-12 Nch Corporation Nutrient rich germinant composition and spore incubation method
US10897922B2 (en) 2016-04-05 2021-01-26 Nch Corporation Composition and method for germinative compounds in probiotic food and beverage products for human consumption
EP3468382A4 (en) * 2016-06-14 2020-01-22 Prevtec Microbia Inc ANIMAL FEED PELLETS WITH FEED ADDITIVE, METHOD FOR THE PRODUCTION AND USE THEREOF
WO2017219106A1 (pt) 2016-06-24 2017-12-28 Yessinergy Holding S/A Composição imunomoduladora e promotora de crescimento e de controle da população de bactérias indesejáveis da microbiota intestinal e seu uso
KR101766430B1 (ko) * 2016-10-28 2017-08-08 주식회사 삼양사 올리고당을 함유하는 알룰로오스 시럽 및 그 제조방법
CN106819418A (zh) * 2017-03-27 2017-06-13 张军军 一种超高脂饲料及其制备方法
US10323226B2 (en) 2017-03-30 2019-06-18 Nch Corporation Feed material for biomass generator
GB201708932D0 (en) * 2017-06-05 2017-07-19 Probi Ab Microbial compositions
CN112543804B (zh) * 2018-07-04 2025-09-23 科·汉森有限公司 包含活益生菌的水性局部组合物
EP3817726A1 (en) 2018-07-04 2021-05-12 Chr. Hansen A/S Topical compositions comprising viable probiotic bacteria
US11401500B2 (en) 2018-08-29 2022-08-02 Nch Corporation System, method, and composition for incubating spores for use in aquaculture, agriculture, wastewater, and environmental remediation applications
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WO2020130770A1 (es) * 2018-12-19 2020-06-25 Ajtzakbio S.A.P.I. De C.V. Composición probiótica de alto valor sin necesidad de cadena de frio, desarrollada para reducir el impacto ambiental, aumentar la producción y mejorar la supervivencia de larvas de camarón
JP2022549133A (ja) * 2019-09-16 2022-11-24 ヴェダンタ バイオサイエンシーズ インコーポレーテッド 細菌を保存するための方法および組成物
CA3155795A1 (en) * 2019-10-22 2021-04-29 Massachusetts Institute Of Technology Biomaterial-based compositions to deliver plant growth promoting microbes
CN110923145B (zh) * 2019-12-16 2021-07-20 天康制药(苏州)有限公司 支原体的冻干保护剂与冻干支原体及其制备方法
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US20230080017A1 (en) * 2020-02-19 2023-03-16 Zantebio Limited Coated microcapsules and methods for the production thereof
RU2746022C1 (ru) * 2020-04-03 2021-04-06 Федеральное государственное бюджетное учреждение "48 Центральный научно-исследовательский институт" Министерства обороны Российской Федерации Способ стабилизации бактериальных клеток чумного микроба перед сублимационным высушиванием
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RU2374859C2 (ru) * 2004-07-13 2009-12-10 Фрисланд Брандз Б.В. Порошкообразная композиция, способ ее получения и применение этой композиции
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