RU2672585C2 - Применение эрибулина и ленватиниба в качестве комбинированной терапии для лечения рака - Google Patents

Применение эрибулина и ленватиниба в качестве комбинированной терапии для лечения рака Download PDF

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RU2672585C2
RU2672585C2 RU2016102158A RU2016102158A RU2672585C2 RU 2672585 C2 RU2672585 C2 RU 2672585C2 RU 2016102158 A RU2016102158 A RU 2016102158A RU 2016102158 A RU2016102158 A RU 2016102158A RU 2672585 C2 RU2672585 C2 RU 2672585C2
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cancer
pharmaceutically acceptable
acceptable salt
eribulin
lenvatinib
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RU2016102158A
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Russian (ru)
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RU2016102158A (ru
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Кенити НОМОТО
Цзяи У
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Эйсай Ар Энд Ди Менеджмент Ко., Лтд.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dermatology (AREA)
RU2016102158A 2013-06-26 2014-06-26 Применение эрибулина и ленватиниба в качестве комбинированной терапии для лечения рака RU2672585C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361839542P 2013-06-26 2013-06-26
US61/839,542 2013-06-26
PCT/JP2014/067723 WO2014208774A1 (en) 2013-06-26 2014-06-26 Use of eribulin and lenvatinib as combination therapy for treatment of cancer

Publications (2)

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RU2016102158A RU2016102158A (ru) 2017-07-31
RU2672585C2 true RU2672585C2 (ru) 2018-11-16

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RU2016102158A RU2672585C2 (ru) 2013-06-26 2014-06-26 Применение эрибулина и ленватиниба в качестве комбинированной терапии для лечения рака

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US (1) US9549922B2 (2)
EP (1) EP3013335B1 (2)
JP (1) JP6404242B2 (2)
KR (1) KR102265952B1 (2)
CN (1) CN105338977B (2)
AU (1) AU2014299699B2 (2)
BR (1) BR112015029386B1 (2)
CA (1) CA2915005C (2)
ES (1) ES2705698T3 (2)
IL (1) IL242386B (2)
RU (1) RU2672585C2 (2)
WO (1) WO2014208774A1 (2)

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JP2016528162A (ja) 2016-09-15
US9549922B2 (en) 2017-01-24
CA2915005C (en) 2021-12-28
AU2014299699A1 (en) 2015-12-10
JP6404242B2 (ja) 2018-10-10
EP3013335A1 (en) 2016-05-04
KR20160023816A (ko) 2016-03-03
EP3013335B1 (en) 2018-11-07
CA2915005A1 (en) 2014-12-31
WO2014208774A1 (en) 2014-12-31
RU2016102158A (ru) 2017-07-31
BR112015029386A8 (pt) 2020-03-17
US20150005343A1 (en) 2015-01-01
ES2705698T3 (es) 2019-03-26
IL242386B (en) 2019-06-30
BR112015029386A2 (pt) 2017-07-25
BR112015029386B1 (pt) 2023-11-14
AU2014299699B2 (en) 2019-10-10
CN105338977A (zh) 2016-02-17
KR102265952B1 (ko) 2021-06-16
CN105338977B (zh) 2018-10-16

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