SE0201328L - Hematopoietisk differentiering av humana embryonala stamceller - Google Patents

Hematopoietisk differentiering av humana embryonala stamceller

Info

Publication number
SE0201328L
SE0201328L SE0201328A SE0201328A SE0201328L SE 0201328 L SE0201328 L SE 0201328L SE 0201328 A SE0201328 A SE 0201328A SE 0201328 A SE0201328 A SE 0201328A SE 0201328 L SE0201328 L SE 0201328L
Authority
SE
Sweden
Prior art keywords
embryonic stem
stem cells
human embryonic
hematopoietic differentiation
cells
Prior art date
Application number
SE0201328A
Other languages
English (en)
Other versions
SE0201328D0 (sv
SE526490C2 (sv
Inventor
Dan S Kaufman
James A Thomson
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of SE0201328D0 publication Critical patent/SE0201328D0/sv
Publication of SE0201328L publication Critical patent/SE0201328L/sv
Publication of SE526490C2 publication Critical patent/SE526490C2/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1394—Bone marrow stromal cells; whole marrow
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
SE0201328A 1999-11-08 2002-05-03 Hematopoietisk differentiering av humana embryonala stamceller SE526490C2 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/435,578 US6280718B1 (en) 1999-11-08 1999-11-08 Hematopoietic differentiation of human pluripotent embryonic stem cells
PCT/US2000/023469 WO2001034776A1 (en) 1999-11-08 2000-08-25 Hematopoietic differentiation of human embryonic stem cells

Publications (3)

Publication Number Publication Date
SE0201328D0 SE0201328D0 (sv) 2002-05-03
SE0201328L true SE0201328L (sv) 2002-07-05
SE526490C2 SE526490C2 (sv) 2005-09-27

Family

ID=23728955

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0201328A SE526490C2 (sv) 1999-11-08 2002-05-03 Hematopoietisk differentiering av humana embryonala stamceller

Country Status (13)

Country Link
US (3) US6280718B1 (sv)
EP (1) EP1228194A1 (sv)
JP (3) JP2003513664A (sv)
KR (2) KR20070047850A (sv)
CN (1) CN1228443C (sv)
AU (1) AU784928B2 (sv)
BR (1) BR0015374A (sv)
CA (1) CA2390281C (sv)
IL (2) IL149387A0 (sv)
IS (1) IS6373A (sv)
NO (1) NO20022180L (sv)
SE (1) SE526490C2 (sv)
WO (1) WO2001034776A1 (sv)

Families Citing this family (193)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7410798B2 (en) * 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
EP1129176A4 (en) * 1998-11-09 2002-10-30 Es Cell Int Pte Ltd EMBRYONIC STEM CELLS
US8252280B1 (en) 1999-08-05 2012-08-28 Regents Of The University Of Minnesota MAPC generation of muscle
US10638734B2 (en) 2004-01-05 2020-05-05 Abt Holding Company Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
US7015037B1 (en) 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
WO2002064748A2 (en) * 2001-02-14 2002-08-22 Furcht Leo T Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
US20030129745A1 (en) 1999-10-28 2003-07-10 Robl James M. Gynogenetic or androgenetic production of pluripotent cells and cell lines, and use thereof to produce differentiated cells and tissues
US6280718B1 (en) * 1999-11-08 2001-08-28 Wisconsin Alumni Reasearch Foundation Hematopoietic differentiation of human pluripotent embryonic stem cells
US6602711B1 (en) * 2000-02-21 2003-08-05 Wisconsin Alumni Research Foundation Method of making embryoid bodies from primate embryonic stem cells
US6534052B1 (en) 2000-09-05 2003-03-18 Yong-Fu Xiao Cardiac function comprising implantation of embryonic stem cell in which differentiation has been initiated
US6607720B1 (en) 2000-09-05 2003-08-19 Yong-Fu Xiao Genetically altered mammalian embryonic stem cells, their living progeny, and their therapeutic application for improving cardiac function after myocardial infarction
EP3299452A1 (en) 2000-12-06 2018-03-28 Anthrogenesis Corporation Method of collecting placental stem cells
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
CA2435826A1 (en) * 2001-01-24 2002-08-01 The Government Of The United States Of America Differentiation of stem cells to pancreatic endocrine cells
CA3046566A1 (en) 2001-02-14 2002-08-22 Anthrogenesis Corporation Post-partum mammalian placental stem cells for use in the treatment of neurological or renal diseases and disorders
US20030211605A1 (en) * 2001-05-01 2003-11-13 Lee Sang-Hun Derivation of midbrain dopaminergic neurons from embryonic stem cells
GB2394958B (en) 2001-07-24 2006-03-01 Es Cell Int Pte Ltd Methods of inducing differentiation of stem cells
WO2003018760A2 (en) * 2001-08-24 2003-03-06 Advanced Cell Technology, Inc. Screening assays for identifying differentiation-inducing agents and production of differentiated cells for cell therapy
DE10144326B4 (de) * 2001-09-10 2005-09-22 Siemens Ag Verfahren und System zur Überwachung eines Reifenluftdrucks
US6759244B2 (en) * 2001-11-08 2004-07-06 Art Institute Of New York And New Jersey, Inc. Composite blastocysts (CBs) from aggregates of dissociated cells of non-viable pre-embryos
CN1596303A (zh) * 2001-11-09 2005-03-16 阿特塞尔科学公司 利用基质细胞支持胚胎干细胞和成体干细胞的方法和组合物
AU2012258384B2 (en) * 2001-12-07 2016-04-21 Asterias Biotherapeutics, Inc. Hematopoietic cells from human embryonic stem cells
AU2016206280B2 (en) * 2001-12-07 2018-05-17 Asterias Biotherapeutics, Inc. Hematopoietic cells from human embryonic stem cells
US20040224403A1 (en) * 2001-12-07 2004-11-11 Robarts Research Institute Reconstituting hematopoietic cell function using human embryonic stem cells
US7799324B2 (en) * 2001-12-07 2010-09-21 Geron Corporation Using undifferentiated embryonic stem cells to control the immune system
CN102008503B (zh) * 2001-12-07 2018-10-09 阿斯特利亚斯生物治疗股份公司 人胚胎干细胞衍生的造血细胞
CA2473909A1 (en) * 2002-01-15 2003-07-24 Advanced Cell Technology, Inc. Cloning b and t lymphocytes
US20030134422A1 (en) * 2002-01-16 2003-07-17 Sayre Chauncey Bigelow Stem cell maturation for all tissue lines
US20050170506A1 (en) * 2002-01-16 2005-08-04 Primegen Biotech Llc Therapeutic reprogramming, hybrid stem cells and maturation
US20050090004A1 (en) * 2003-01-16 2005-04-28 Sayre Chauncey B. Stem cell maturation for all tissue lines
AU2003222043A1 (en) * 2002-03-18 2003-10-08 National Jewish Medical And Research Center Method for production of neutrophils and uses therefor
US7498171B2 (en) * 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
GB0210741D0 (en) * 2002-05-10 2002-06-19 Medical Res Council Methods of therapy
US20040091936A1 (en) 2002-05-24 2004-05-13 Michael West Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank
EP1513928B1 (en) 2002-05-24 2019-08-21 Advanced Cell Technology, Inc. A bank of stem cells for producing cells for transplantation having hla antigens matching those of transplant recipients, and methods for making and using such a stem cell bank
EP1525308A4 (en) * 2002-05-30 2006-11-02 Celgene Corp METHODS OF USING JNK OR MKK INHIBITORS TO MODULATE CELL DIFFERENTIATION AND TREAT MYELOPROLIFERATIVE DISORDERS AND MYELODYSPLASIC SYNDROMES
EP1534068A4 (en) * 2002-08-08 2006-08-23 Univ Georgia Res Found COMPOSITIONS AND METHODS FOR NEURALE DIFFERENTIATION OF EMBRYOSTAMIC CELLS
AU2003286442A1 (en) * 2002-10-16 2004-05-04 Advanced Cell Technology, Inc. Methods using gene trapped stem cells for marking pathways of stem cell differentiation and making and isolating differentiated cells
GB0224415D0 (en) * 2002-10-21 2002-11-27 Medical Res Council Compositions
KR20050086780A (ko) 2002-11-26 2005-08-30 안트로제네시스 코포레이션 세포요법제, 세포요법제 단위 및 이를 이용한 치료방법
EP1567639A4 (en) * 2002-12-05 2005-12-21 Technion Res & Dev Foundation CULTURE OF HUMAN PANCREATIC ISLANDS AND USES THEREOF
US20040110286A1 (en) * 2002-12-06 2004-06-10 The John P. Robarts Research Institute Method for making hematopoietic cells
JP2006517975A (ja) * 2003-02-13 2006-08-03 アンスロジェネシス コーポレーション 疾患、障害または症状を患っている個体を治療するための臍帯血の使用
US20060177929A1 (en) * 2003-03-24 2006-08-10 Klug Christopher A Regulation of self-renewal in stem cells
US8252588B2 (en) 2003-04-08 2012-08-28 Yeda Research And Development Co. Ltd. Stem cells having increased sensitivity to SDF-1 and methods of generating and using same
FR2853551B1 (fr) 2003-04-09 2006-08-04 Lab Francais Du Fractionnement Formulation stabilisante pour compositions d'immunoglobulines g sous forme liquide et sous forme lyophilisee
JP2007535486A (ja) * 2003-05-07 2007-12-06 ラ ホーヤ インスティチュート フォー モレキュラー メディシン 高分子量のヒアルロン酸を用いた内因性又は埋め込まれた又は移植された幹細胞の機能回復を促進するための方法
CA2542276A1 (en) * 2003-10-16 2005-04-28 The University Court Of The University Of Edinburgh Control of es cell self-renewal and lineage specification, and medium therefor
IL158868A0 (en) * 2003-11-13 2004-05-12 Yeda Res & Dev Methods of generating and using stem cells enriched with immature primitive progenitor
WO2005049812A1 (en) * 2003-11-19 2005-06-02 Australian Stem Cell Centre Limited Methods for producing blood products from pluripotent cells in cell culture
US20070269412A1 (en) * 2003-12-02 2007-11-22 Celavie Biosciences, Llc Pluripotent cells
WO2005056755A2 (en) * 2003-12-02 2005-06-23 Catholic Healthcare West Compositions and methods for propagation of neural progenitor cells
GB2441530B (en) * 2004-02-12 2009-09-23 Univ Newcastle Stem Cells
US20050232905A1 (en) * 2004-03-26 2005-10-20 Yeh Edward T Use of peripheral blood cells for cardiac regeneration
WO2005097979A2 (en) * 2004-03-31 2005-10-20 Newlink Genetics Corporation Methods and compositions for obtaining hematopoietic stem cells derived from embryonic stem cells and uses thereof
US7622108B2 (en) * 2004-04-23 2009-11-24 Bioe, Inc. Multi-lineage progenitor cells
WO2005108559A2 (en) * 2004-04-23 2005-11-17 Bioe, Inc. Multi-lineage progenitor cells
EP1745125A1 (en) * 2004-05-14 2007-01-24 Becton, Dickinson and Company Cell culture environments for the serum-free expansion of mesenchymal stem cells
AU2005271723B2 (en) 2004-07-13 2010-12-16 Asterias Biotherapeutics, Inc. Medium for growing human embryonic stem cells
CA2504451A1 (en) * 2004-08-10 2006-02-10 Geron Corporation Dendritic cell vaccines for treating cancer made from embryonic stem cells
US8354277B2 (en) * 2004-10-12 2013-01-15 Technion Research & Development Foundation Ltd. Isolated primate embryonic cells derived from extended blastocysts
NZ554866A (en) * 2004-11-01 2010-12-24 Wisconsin Alumni Res Found Platelets from stem cells
US20070077654A1 (en) * 2004-11-01 2007-04-05 Thomson James A Platelets from stem cells
US20060263879A1 (en) * 2004-12-30 2006-11-23 Stemlifeline, Inc. Methods and systems relating to embryonic stem cell lines
WO2006073911A1 (en) * 2004-12-30 2006-07-13 Stemlifeline, Inc. Methods and compositions relating to embryonic stem cell lines
EP1856248A4 (en) * 2005-02-09 2010-01-20 Burnham Inst Medical Research HOMOGENEOUS NEURALE CURRENT CELLS
EP1877547B1 (en) 2005-05-04 2012-08-08 Commonwealth Scientific and Industrial Research Organisation Selecting, culturing and creating lineage committed hematopoietic stem cells
CA2610243C (en) * 2005-06-01 2016-11-15 Wisconsin Alumni Research Foundation Method of forming dendritic cells from embryonic stem cells
US8034613B2 (en) * 2005-06-01 2011-10-11 Wisconsin Alumni Research Foundation Multipotent lymphohematopoietic progenitor cells
US9074181B2 (en) 2005-06-22 2015-07-07 Asterias Biotherapeutics, Inc. Suspension culture of human embryonic stem cells
KR20130099253A (ko) 2005-06-22 2013-09-05 제론 코포레이션 영장류 다능성 줄기 세포의 심근세포 계통 세포로의 분화
WO2007011088A1 (en) * 2005-07-20 2007-01-25 Seoul National University Industry Foundation Method for culturingand proliferating hematopoietic stem cells and progenitor cells using human endometrial cells
EP1957633B1 (en) 2005-10-13 2013-12-18 Anthrogenesis Corporation Immunomodulation using placental stem cells
CN103773804A (zh) 2005-12-13 2014-05-07 国立大学法人京都大学 核重新编程因子
US8129187B2 (en) 2005-12-13 2012-03-06 Kyoto University Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2
US8278104B2 (en) 2005-12-13 2012-10-02 Kyoto University Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
US20090227032A1 (en) 2005-12-13 2009-09-10 Kyoto University Nuclear reprogramming factor and induced pluripotent stem cells
ES2711278T3 (es) 2005-12-29 2019-04-30 Celularity Inc Poblaciones de células madre placentarias
CN101389754A (zh) 2005-12-29 2009-03-18 人类起源公司 胎盘干细胞和第二来源干细胞的联合培养
EP2019858B1 (en) * 2006-04-17 2012-06-13 BioE LLC Differentiation of multi-lineage progenitor cells to respiratory epithelial cells
US8809052B2 (en) * 2006-08-28 2014-08-19 Yeda Research And Development Co. Ltd. Methods of generating mature oligodendrocytes
US20080108044A1 (en) * 2006-11-08 2008-05-08 Deepika Rajesh In vitro differentiation of hematopoietic cells from primate embryonic stem cells
US9005964B2 (en) * 2006-11-24 2015-04-14 Regents Of The University Of Minnesota Endodermal progenitor cells
US7883698B2 (en) * 2007-01-17 2011-02-08 Maria Michejda Isolation and preservation of fetal hematopoietic and mesencymal system cells from non-controversial materials and/or tissues resulting from miscarriages and methods of therapeutic use
NZ597779A (en) 2007-02-12 2013-07-26 Anthrogenesis Corp Treatment of inflammatory diseases using placental stem cells
US9213999B2 (en) 2007-06-15 2015-12-15 Kyoto University Providing iPSCs to a customer
WO2008156708A2 (en) * 2007-06-15 2008-12-24 Massachusetts Institute Of Technology Methods and compositions for enhanced differentiation from embryonic stem cells
JP2008307007A (ja) 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
EP2192908A4 (en) * 2007-07-25 2010-09-01 Bioe Inc DIFFERENTIATION OF PRECURSOR CELLS OF MULTIPLE ABSTRACTS AGAINST CHONDROCYTES
PT2203176E (pt) 2007-09-28 2015-03-02 Anthrogenesis Corp Supressão de tumor utilizando perfusato placentário humano e células assassinas naturais intermédias derivadas de placenta humanas
US9683232B2 (en) 2007-12-10 2017-06-20 Kyoto University Efficient method for nuclear reprogramming
JP5558097B2 (ja) 2007-12-10 2014-07-23 国立大学法人京都大学 効率的な核初期化方法
US10316288B2 (en) * 2008-04-30 2019-06-11 Sanbio, Inc. Neural regenerating cells with alterations in DNA methylation
CN101855350B (zh) 2008-05-02 2014-12-31 国立大学法人京都大学 核重编程序方法
US20090291494A1 (en) * 2008-05-21 2009-11-26 Bioe, Inc. Differentiation of Multi-Lineage Progenitor Cells to Pancreatic Cells
AU2009283216B2 (en) 2008-08-20 2015-04-02 Celularity Inc. Improved cell composition and methods of making the same
PE20110399A1 (es) 2008-08-20 2011-06-22 Anthrogenesis Corp Tratamiento de la apoplejia utilizando celulas placentarias aisladas
KR20110050688A (ko) 2008-08-22 2011-05-16 안트로제네시스 코포레이션 태반 세포 집단을 이용한 골 결함의 치료 방법 및 골 결함 치료 조성물
MX2011005229A (es) 2008-11-19 2011-06-16 Anthrogenesis Corp Celulas adherentes derivadas del amnios.
US20100209399A1 (en) * 2009-02-13 2010-08-19 Celavie Biosciences, Llc Brain-derived stem cells for repair of musculoskeletal system in vertebrate subjects
EP2420563A4 (en) 2009-02-24 2013-02-20 Kanazawa Medical University METHOD FOR THE DENUKLEATION OF NUCLEARED ERYTHROCYTES AND THE DEKULATION DERIVATIVES
US9388381B2 (en) 2009-07-09 2016-07-12 Massachusetts Institute Of Technology Methods and compositions for increased safety of stem cell-derived populations
NZ598457A (en) * 2009-08-03 2014-06-27 Recombinetics Inc Methods and compositions for targeted gene modification
CA2777552C (en) 2009-10-19 2019-05-21 Cellular Dynamics International, Inc. Cardiomyocyte production
MX2012008636A (es) 2010-01-26 2012-10-15 Anthrogenesis Corp Tratamiento de canceres relacionados con el hueso utilizando celulas madre placenterias.
US9254302B2 (en) 2010-04-07 2016-02-09 Anthrogenesis Corporation Angiogenesis using placental stem cells
EP2555783A1 (en) 2010-04-08 2013-02-13 Anthrogenesis Corporation Treatment of sarcoidosis using placental stem cells
WO2011159797A2 (en) 2010-06-15 2011-12-22 Cellular Dynamics International, Inc. A compendium of ready-built stem cell models for interrogation of biological response
KR20220053695A (ko) 2010-07-13 2022-04-29 셀룰래리티 인코포레이티드 천연 킬러 세포의 생성 방법
WO2012018933A2 (en) 2010-08-04 2012-02-09 Cellular Dynamics International, Inc. Reprogramming immortalized b cells
CA2838330C (en) 2010-08-23 2021-01-26 President And Fellows Of Harvard College Optogenetic probes for measuring membrane potential
EP2625264B1 (en) 2010-10-08 2022-12-07 Terumo BCT, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
EP2630232A4 (en) 2010-10-22 2014-04-02 Biotime Inc METHOD FOR MODIFYING TRANSCRIPTIONAL REGULATORY NETWORKS IN STEM CELLS
AU2011352036A1 (en) 2010-12-31 2013-07-18 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
CA2829006A1 (en) 2011-03-04 2012-09-13 The Regents Of The University Of California Locally released growth factors to mediate motor recovery after stroke
CA2829804A1 (en) 2011-03-29 2012-10-04 Geron Corporation Enriched populations of cardiomyocyte lineage cells from pluripotent stem cells
EP2694080B1 (en) 2011-04-06 2018-03-14 SanBio, Inc. Methods and compositions for modulating peripheral immune function
ES2707579T3 (es) 2011-06-01 2019-04-04 Celularity Inc Tratamiento del dolor usando citoblastos placentarios
US10865383B2 (en) 2011-07-12 2020-12-15 Lineage Cell Therapeutics, Inc. Methods and formulations for orthopedic cell therapy
US20130058905A1 (en) 2011-08-23 2013-03-07 Igor Slukvin Angiohematopoietic Progenitor Cells
US9925221B2 (en) 2011-09-09 2018-03-27 Celularity, Inc. Treatment of amyotrophic lateral sclerosis using placental stem cells
EP2594295A1 (en) 2011-11-16 2013-05-22 Servicio Andaluz De Salud Nerve implants based on a compacted biomaterial containing cells
US9447378B2 (en) 2012-04-27 2016-09-20 Massachusetts Institute Of Technology Method for differentiating human embryonic stem cells into β-cells for the treatment of type I diabetes
JP5432322B2 (ja) 2012-05-08 2014-03-05 株式会社大塚製薬工場 トレハロース含有肺塞栓形成予防用哺乳動物細胞懸濁液
AU2013237760A1 (en) 2012-10-08 2014-04-24 Biotime, Inc. Differentiated progeny of clonal progenitor cell lines
US9763983B2 (en) 2013-02-05 2017-09-19 Anthrogenesis Corporation Natural killer cells from placenta
EP2987852A4 (en) 2013-04-17 2016-09-07 Nissan Chemical Ind Ltd MEDIA COMPOSITION AND METHOD FOR THE PRODUCTION OF ERYTHROCYTES THEREWITH
JP6529486B2 (ja) 2013-06-05 2019-06-12 バイオタイム インク．Ｂｉｏｔｉｍｅ Ｉｎｃ． 哺乳動物種における誘導組織再生のための組成物および方法
US9816070B2 (en) 2013-06-14 2017-11-14 Massachusetts Institute Of Technology Articles and methods for stem cell differentiation
SG10201710158QA (en) 2013-06-28 2018-01-30 Otsuka Pharma Factory Inc Trehalose- and dextran-containing solution for transplanting mammalian cells
EP3068866B1 (en) 2013-11-16 2018-04-25 Terumo BCT, Inc. Expanding cells in a bioreactor
CN103740642A (zh) * 2014-01-28 2014-04-23 娄彩玲 一种生产人红细胞的方法
US11078462B2 (en) 2014-02-18 2021-08-03 ReCyte Therapeutics, Inc. Perivascular stromal cells from primate pluripotent stem cells
JP6783143B2 (ja) 2014-03-25 2020-11-11 テルモ ビーシーティー、インコーポレーテッド 培地の受動的補充
US10240127B2 (en) 2014-07-03 2019-03-26 ReCyte Therapeutics, Inc. Exosomes from clonal progenitor cells
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
CN107002040B (zh) 2014-10-24 2021-08-10 大日本住友制药株式会社 视网膜组织的制备方法
US10286009B2 (en) * 2015-05-16 2019-05-14 Asterias Biotherapeutics, Inc. Pluripotent stem cell-derived oligodendrocyte progenitor cells for the treatment of spinal cord injury
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
MY189778A (en) 2015-09-08 2022-03-04 Healios Kk Method for producing retinal pigment epithelial cells
AU2016366158B2 (en) 2015-12-07 2023-02-23 Agex Therapeutics, Inc. Methods for the re-derivation of diverse pluripotent stem cell-derived brown fat cells
EP3423158B1 (en) 2016-02-24 2023-11-15 The Rockefeller University Embryonic cell-based therapeutic candidate screening systems, models for huntington's disease and uses thereof
AU2017240591B2 (en) 2016-03-30 2023-08-24 Asterias Biotherapeutics, Inc. Oligodendrocyte progenitor cell compositions
CN109415696A (zh) 2016-05-25 2019-03-01 泰尔茂比司特公司 细胞扩增
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
JP7006943B2 (ja) 2016-11-04 2022-01-24 国立大学法人 東京大学 間葉系細胞及び間葉系幹細胞の凍結保存用溶液、凍結物、及び凍結保存方法
CA3044509A1 (en) 2016-11-25 2018-05-31 Riken Cell population for transplantation and method for producing same
US11889829B2 (en) 2016-12-14 2024-02-06 Otsuka Pharmaceutical Factory, Inc. Mammalian cell cryopreservation liquid
JP7007686B2 (ja) 2017-03-08 2022-01-25 大日本住友製薬株式会社 網膜色素上皮細胞の製造方法
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
US11702634B2 (en) 2017-03-31 2023-07-18 Terumo Bct, Inc. Expanding cells in a bioreactor
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
WO2019017492A1 (ja) 2017-07-20 2019-01-24 国立研究開発法人理化学研究所 連続的な上皮を含む網膜組織の成熟化方法
CA3070212A1 (en) 2017-07-20 2019-01-24 Riken Method for preserving neural tissue
KR102604618B1 (ko) 2017-09-08 2023-11-22 고쿠리쓰 겐큐 가이하쓰 호징 리가가쿠 겐큐소 망막 조직을 포함하는 세포 응집체 및 그의 제조 방법
JP7360583B2 (ja) 2017-09-14 2023-10-13 国立研究開発法人理化学研究所 網膜組織の製造方法
CN111094548A (zh) 2017-09-14 2020-05-01 国立研究开发法人理化学研究所 基于背侧化信号转导物质或腹侧化信号转导物质的增加视锥细胞或视杆细胞的方法
SG11202004829WA (en) 2017-11-24 2020-06-29 Sumitomo Chemical Co Method for producing cell mass including pituitary tissue, and cell mass thereof
WO2019103125A1 (ja) 2017-11-24 2019-05-31 住友化学株式会社 神経系細胞又は神経組織と非神経上皮組織とを含む細胞塊の製造方法及びその細胞塊
EP3757208A4 (en) 2018-02-19 2021-12-01 Sumitomo Dainippon Pharma Co., Ltd. CELL UNIT, MIXTURE OF CELL UNITS AND METHOD OF MANUFACTURING THEREOF
US20210308188A1 (en) 2018-08-24 2021-10-07 Sumitomo Chemical Company, Limited Cell cluster including olfactory neuron or precursor cell thereof, and method for producing same
CN113646422B (zh) 2018-09-19 2025-03-11 谱系细胞疗法股份有限公司 用于在动态悬浮培养中分化多能干细胞的方法
JPWO2020066991A1 (ja) 2018-09-28 2021-08-30 株式会社大塚製薬工場 アカルボース又はスタキオースを含む哺乳動物細胞保存用液
WO2020100481A1 (ja) 2018-11-15 2020-05-22 Jsr株式会社 脳オルガノイドの製造方法
WO2020130068A1 (ja) 2018-12-20 2020-06-25 住友化学株式会社 胚型赤芽球を含む細胞集団及びその製造方法、細胞培養組成物並びに化合物試験法
CA3122791A1 (en) 2018-12-28 2020-07-02 Riken Therapeutic drug for disease accompanied by disorders in retinal cells or retinal tissue
CN120060141A (zh) 2019-01-23 2025-05-30 阿斯特里亚斯生物疗法股份有限公司 来自人多能干细胞的背源性少突胶质祖细胞
CA3132804A1 (en) 2019-03-13 2020-09-17 Sumitomo Dainippon Pharma Co., Ltd. Method for evaluating quality of transplant neural retina, and transplant neural retina sheet
CA3137528A1 (en) 2019-04-26 2020-10-29 Riken Composite including neural retina, retinal pigment epithelial cells, and hydrogel, and method for producing same
CN113728089A (zh) 2019-04-26 2021-11-30 株式会社大塚制药工场 含海藻糖的哺乳动物细胞保存用液
CN114375328B (zh) 2019-09-06 2024-12-27 学校法人庆应义塾 包含胶质前体细胞的细胞聚集体的制备方法
IL293137A (en) 2019-11-20 2022-07-01 Sumitomo Pharma Co Ltd A method for freezing nerve cells
CN115003156A (zh) 2019-11-20 2022-09-02 住友制药株式会社 冷冻细胞聚集体的方法
JPWO2022054925A1 (sv) 2020-09-11 2022-03-17
WO2022054924A1 (ja) 2020-09-11 2022-03-17 大日本住友製薬株式会社 移植用組織のための媒体
TW202302839A (zh) 2021-03-09 2023-01-16 國立研究開發法人理化學研究所 低免疫原性視網膜色素上皮細胞之製造方法
US12043823B2 (en) 2021-03-23 2024-07-23 Terumo Bct, Inc. Cell capture and expansion
CN117769591A (zh) 2021-06-17 2024-03-26 国立大学法人京都大学 源自人多能干细胞的大脑皮质细胞制剂的制造方法
KR20240056604A (ko) 2021-09-13 2024-04-30 후지필름 셀룰러 다이내믹스, 인코포레이티드 수임 심장 전구세포의 제조 방법
US20240400622A1 (en) 2021-09-23 2024-12-05 President And Fellows Of Harvard College Genetically encoded voltage indicators and uses thereof
KR20240093530A (ko) 2021-09-30 2024-06-24 스미토모 파마 가부시키가이샤 뇌하수체 호르몬 생산 세포를 포함하는 세포 응집체 및 그 생산 방법
WO2023054396A1 (ja) 2021-09-30 2023-04-06 住友化学株式会社 下垂体組織を含む細胞集団の製造方法及びその細胞集団
KR20240103018A (ko) 2021-11-19 2024-07-03 고쿠리쓰 겐큐 가이하쓰 호징 리가가쿠 겐큐소 시트상 망막 조직의 제조 방법
EP4458954A1 (en) 2021-12-27 2024-11-06 Sumitomo Pharma Co., Ltd. Neural crest cell culturing method and production method
US12209689B2 (en) 2022-02-28 2025-01-28 Terumo Kabushiki Kaisha Multiple-tube pinch valve assembly
JPWO2023176906A1 (sv) 2022-03-16 2023-09-21
WO2023199641A1 (ja) 2022-04-12 2023-10-19 株式会社大塚製薬工場 哺乳動物細胞凍結保存液
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device
EP4594471A1 (en) 2022-09-30 2025-08-06 Fujifilm Cellular Dynamics, Inc. Methods for the production of cardiac fibroblasts
JPWO2024172043A1 (sv) 2023-02-14 2024-08-22
JPWO2024195789A1 (sv) 2023-03-20 2024-09-26
WO2024204596A1 (ja) 2023-03-29 2024-10-03 住友ファーマ株式会社 網膜組織の製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635386A (en) * 1989-06-15 1997-06-03 The Regents Of The University Of Michigan Methods for regulating the specific lineages of cells produced in a human hematopoietic cell culture
NZ314644A (en) * 1993-05-24 2000-11-24 Immunex Corp Use of flt3-ligands as a growth stimulator of stem cells in the transplantation of tissue
US5914268A (en) 1994-11-21 1999-06-22 National Jewish Center For Immunology & Respiratory Medicine Embryonic cell populations and methods to isolate such populations
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
CA2262817A1 (en) 1996-08-19 1998-02-26 James Robl Embryonic or stem-like cell lines produced by cross species nuclear transplantation
US6280718B1 (en) * 1999-11-08 2001-08-28 Wisconsin Alumni Reasearch Foundation Hematopoietic differentiation of human pluripotent embryonic stem cells

Also Published As

Publication number Publication date
CA2390281A1 (en) 2001-05-17
CN1387565A (zh) 2002-12-25
US6613568B2 (en) 2003-09-02
US20040043484A1 (en) 2004-03-04
AU784928B2 (en) 2006-07-27
KR20030022766A (ko) 2003-03-17
IS6373A (is) 2002-05-06
US20020015694A1 (en) 2002-02-07
CN1228443C (zh) 2005-11-23
CA2390281C (en) 2005-10-25
JP2010042011A (ja) 2010-02-25
IL149387A0 (en) 2002-11-10
KR20070047850A (ko) 2007-05-07
NO20022180L (no) 2002-06-03
JP2014000096A (ja) 2014-01-09
SE0201328D0 (sv) 2002-05-03
IL149387A (en) 2008-08-07
NO20022180D0 (no) 2002-05-07
US6280718B1 (en) 2001-08-28
SE526490C2 (sv) 2005-09-27
WO2001034776A1 (en) 2001-05-17
BR0015374A (pt) 2002-12-24
JP2003513664A (ja) 2003-04-15
EP1228194A1 (en) 2002-08-07
AU6940400A (en) 2001-06-06

Similar Documents

Publication Publication Date Title
SE0201328L (sv) Hematopoietisk differentiering av humana embryonala stamceller
NO20033396L (no) Forbedret in vitro fremgangsmåte for dyrking av mammale celler for autologcelle implantasjon/transplantasjon fremgangsmåter
WO2021041443A3 (en) Organoid mesoderm lineage diversification
Terai et al. Immortalization of human fetal cells: the life span of umbilical cord blood-derived cells can be prolonged without manipulating p16INK4a/RB braking pathway
WO2003014313A3 (en) Alternative compositions and methods for the culture of stem cells
WO2002072762A3 (en) Use of rna interference for the creation of lineage specific es and other undifferentiated cells and production of differentiated cells in vitro by co-culture
JP2003513664A5 (sv)
DK1218489T3 (da) Pluripotente embryonlignende stamceller, præparater, fremgangsmåder og anvendelse deraf
WO2001081549A3 (en) Hepatocyte lineage cells derived from pluripotent stem cells
IL207268A0 (en) Methods of culture systems of preparing feeder cells - free, xeno - free human embryonic stem cells and stem cell cultures prepared using same
WO2003038076A1 (en) Immortalized mesenchymal cells and utilization thereof
ATE489456T1 (de) Menschliche hornhautendothelzellen und verfahren zur gewinnung und kultivierung von zellen zur hornhautzelltransplantation
ATE430807T1 (de) Verfahren zur kultivierung von circovirus
WO2004090096A3 (en) Methods for neural differentiation of embryonic stem cells using protease passaging techniques
EP1155114A4 (en) PLURIPOTENTE EMBRYONAL Germ cell line from birds
ATE548447T1 (de) Menschlicher hepatische vorläuferzellen und verfahren zur verwendung davon
Chim et al. Human circulating peripheral blood mononuclear cells for calvarial bone tissue engineering
ATE517176T1 (de) Verfahren zur kultivierung von geschmackszellen aus säugern
Quílez et al. In vitro induction of hair follicle signatures using human dermal papilla cells encapsulated in fibrin microgels
Urkasemsin et al. Unveiling stem cell heterogeneity toward the development of salivary gland regenerative strategies
WO2004113515A3 (en) Tissue modeling in embryonic stem (es) cell system
Vallmajo‐Martin et al. Undifferentiated human amniotic fluid progenitor cells promote bone regeneration in vivo
WO2004078916A3 (en) In vitro micro-organs, and uses related thereto
MXPA02001400A (es) Lineas de celulas blastodermicas de ave.
Proulx et al. Stem cells of the skin and cornea: their clinical applications in regenerative medicine