SE0400410D0 - New compounds - Google Patents
New compoundsInfo
- Publication number
- SE0400410D0 SE0400410D0 SE0400410A SE0400410A SE0400410D0 SE 0400410 D0 SE0400410 D0 SE 0400410D0 SE 0400410 A SE0400410 A SE 0400410A SE 0400410 A SE0400410 A SE 0400410A SE 0400410 D0 SE0400410 D0 SE 0400410D0
- Authority
- SE
- Sweden
- Prior art keywords
- omeprazole
- benzimidazole
- enantiomer
- thio
- methoxy
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 abstract 2
- ATTZFSUZZUNHBP-UHFFFAOYSA-N Piperonyl sulfoxide Chemical compound CCCCCCCCS(=O)C(C)CC1=CC=C2OCOC2=C1 ATTZFSUZZUNHBP-UHFFFAOYSA-N 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 229960000381 omeprazole Drugs 0.000 abstract 2
- 125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 238000001953 recrystallisation Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0400410A SE0400410D0 (sv) | 2004-02-20 | 2004-02-20 | New compounds |
| HK07104871.9A HK1098474B (en) | 2004-02-20 | 2005-02-17 | New compounds useful for the synthesis of s-and r-omeprazole and a process for their preparation |
| EP05711081A EP1718636B1 (de) | 2004-02-20 | 2005-02-17 | Neue zur synthese von s- und r-omeprazol geeignete verbindungen und ein verfahren zu deren herstellung |
| ES05711081T ES2378237T3 (es) | 2004-02-20 | 2005-02-17 | Nuevos compuestos útiles para la sÃntesis de S y R-omeprazol y un procedimiento para su preparación |
| AT05711081T ATE541838T1 (de) | 2004-02-20 | 2005-02-17 | Neue zur synthese von s- und r-omeprazol geeignete verbindungen und ein verfahren zu deren herstellung |
| PCT/SE2005/000221 WO2005080374A1 (en) | 2004-02-20 | 2005-02-17 | New compounds useful for the synthesis of s- and r-omeprazole and a process for their preparation |
| CA2553877A CA2553877C (en) | 2004-02-20 | 2005-02-17 | Compounds useful for the synthesis of s- and r-omeprazole and a process for their preparation |
| US11/060,138 US20050187256A1 (en) | 2004-02-20 | 2005-02-17 | New compounds useful for the synthesis of S- and R-omeprazole and a process for their preparation |
| JP2006554057A JP2007523160A (ja) | 2004-02-20 | 2005-02-17 | S−及びr−オメプラゾールの合成に有用な新規化合物並びにその製造方法 |
| US10/588,056 US20080255199A1 (en) | 2004-02-20 | 2005-02-17 | Compounds Useful for the Synthesis of S- and R-Omeprazole and a Process for Their Preparation |
| US11/689,801 US20070161682A1 (en) | 2004-02-20 | 2007-03-22 | Compounds Useful for the Synthesis of S- and R-Omeprazole and a Process for their Preparation |
| US12/329,077 US8697880B2 (en) | 2004-02-20 | 2008-12-05 | Compounds useful for the synthesis of S- and R-omeprazole and a process for their preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0400410A SE0400410D0 (sv) | 2004-02-20 | 2004-02-20 | New compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE0400410D0 true SE0400410D0 (sv) | 2004-02-20 |
Family
ID=31989582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0400410A SE0400410D0 (sv) | 2004-02-20 | 2004-02-20 | New compounds |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20080255199A1 (de) |
| EP (1) | EP1718636B1 (de) |
| JP (1) | JP2007523160A (de) |
| AT (1) | ATE541838T1 (de) |
| CA (1) | CA2553877C (de) |
| ES (1) | ES2378237T3 (de) |
| SE (1) | SE0400410D0 (de) |
| WO (1) | WO2005080374A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0400410D0 (sv) * | 2004-02-20 | 2004-02-20 | Astrazeneca Ab | New compounds |
| WO2007088559A1 (en) * | 2006-02-01 | 2007-08-09 | Jubilant Organosys Limited | Process for producing substituted sulphoxides |
| US7579476B2 (en) * | 2006-02-24 | 2009-08-25 | Praktikatalyst Pharma, Llc | Transition metal mediated oxidation of hetero atoms in organic molecules coordinated to transition metals |
| WO2009066321A2 (en) * | 2007-10-03 | 2009-05-28 | Ipca Laboratories Limited | Process for optically active sulfoxide compounds |
| WO2010011856A2 (en) * | 2008-07-23 | 2010-01-28 | Board Of Regents Of The University Of Nebraska | Stereospecificity of methylsulfinyl reduction |
| CN108484578B (zh) * | 2018-04-09 | 2019-03-26 | 珠海润都制药股份有限公司 | 一种艾司奥美拉唑杂质制备的方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| SE8301182D0 (sv) | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
| ES2026761A6 (es) | 1990-10-31 | 1992-05-01 | Genesis Para La Investigacion | Procedimiento de obtencion del omeprazol. |
| DE4035455A1 (de) | 1990-11-08 | 1992-05-14 | Byk Gulden Lomberg Chem Fab | Enantiomerentrennung |
| SE9301830D0 (sv) | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| SE504459C2 (sv) * | 1994-07-15 | 1997-02-17 | Astra Ab | Förfarande för framställning av substituerade sulfoxider |
| HRP960232A2 (en) * | 1995-07-03 | 1998-02-28 | Astra Ab | A process for the optical purification of compounds |
| TW385306B (en) * | 1996-11-14 | 2000-03-21 | Takeda Chemical Industries Ltd | Method for producing crystals of benzimidazole derivatives |
| SE510666C2 (sv) * | 1996-12-20 | 1999-06-14 | Astra Ab | Nya Kristallmodifikationer |
| WO1998040377A1 (en) * | 1997-03-07 | 1998-09-17 | A/S Gea Farmaceutisk Fabrik | Process for the preparation of 2-[[(2-pyridinyl)methyl]sulfinyl]-1h-benzimidazoles and novel compounds of use for such purpose |
| AU5982298A (en) * | 1997-03-07 | 1998-09-29 | A/S Gea Farmaceutisk Fabrik | Process for the preparation of 2-{{(2-pyridinyl)me thyl}sulfinyl}-1h-benzimidazoles and novel compounds of use for such purpos |
| US6303787B1 (en) * | 1998-05-27 | 2001-10-16 | Natco Pharma Limited | Intermediates and an improved process for the preparation of Omeprazole employing the said intermediates |
| ES2166269B1 (es) * | 1999-07-14 | 2003-04-01 | Sint Quimica Sa | Nuevo procedimiento de obtencion de derivados de 2-(2-piridinilmetilsulfinil)-1h-benzimidazol. |
| PT102361B (pt) | 1999-09-22 | 2002-07-31 | Herbex Produtos Quimicos Lda | Metodo de obrencao de arileteres e tioeteres utilizando radiacao micro-ondas |
| CN1193024C (zh) * | 2000-04-28 | 2005-03-16 | 武田药品工业株式会社 | 生产旋光的亚砜衍生物的方法 |
| EP1293507B1 (de) * | 2000-05-15 | 2007-11-28 | Takeda Pharmaceutical Company Limited | Verfahren zur herstellung eines kristalls |
| WO2003097606A1 (en) | 2000-07-28 | 2003-11-27 | Herbex, Produtos Químicos, Sa | New method for the preparation of the anti-ulcer compounds omeprazole, lansoprazole and pantoprazole |
| ES2187248B1 (es) | 2000-08-25 | 2004-01-16 | Sint Quimica Sa | Nuevo procedimiento de obtencion de derivados de 2-(2-piridinilmetilsulfinil)-1h-benzimidazol. |
| AU2003262375A1 (en) * | 2002-04-22 | 2003-11-03 | Sun Pharmaceutical Industries Limited | Optically active substituted pyridinylmethyl-sulphinyl-benzimidazole and salts |
| WO2005054228A1 (en) | 2003-12-05 | 2005-06-16 | Hetero Drugs Limited | A process for the preparation of substitited pyridinylmethylsulfinyl- benzimidazole enantiomers |
| SE0400410D0 (sv) | 2004-02-20 | 2004-02-20 | Astrazeneca Ab | New compounds |
-
2004
- 2004-02-20 SE SE0400410A patent/SE0400410D0/xx unknown
-
2005
- 2005-02-17 WO PCT/SE2005/000221 patent/WO2005080374A1/en not_active Ceased
- 2005-02-17 US US10/588,056 patent/US20080255199A1/en not_active Abandoned
- 2005-02-17 JP JP2006554057A patent/JP2007523160A/ja active Pending
- 2005-02-17 CA CA2553877A patent/CA2553877C/en not_active Expired - Fee Related
- 2005-02-17 AT AT05711081T patent/ATE541838T1/de active
- 2005-02-17 US US11/060,138 patent/US20050187256A1/en not_active Abandoned
- 2005-02-17 EP EP05711081A patent/EP1718636B1/de not_active Expired - Lifetime
- 2005-02-17 ES ES05711081T patent/ES2378237T3/es not_active Expired - Lifetime
-
2007
- 2007-03-22 US US11/689,801 patent/US20070161682A1/en not_active Abandoned
-
2008
- 2008-12-05 US US12/329,077 patent/US8697880B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005080374A1 (en) | 2005-09-01 |
| CA2553877A1 (en) | 2005-09-01 |
| US20080255199A1 (en) | 2008-10-16 |
| CA2553877C (en) | 2012-07-31 |
| US8697880B2 (en) | 2014-04-15 |
| US20050187256A1 (en) | 2005-08-25 |
| ES2378237T3 (es) | 2012-04-10 |
| ATE541838T1 (de) | 2012-02-15 |
| US20090253911A1 (en) | 2009-10-08 |
| EP1718636B1 (de) | 2012-01-18 |
| JP2007523160A (ja) | 2007-08-16 |
| EP1718636A1 (de) | 2006-11-08 |
| US20070161682A1 (en) | 2007-07-12 |
| HK1098474A1 (en) | 2007-07-20 |
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