SE409860B - En ny mellanprodukt for framstellning av terapeutiskt aktiva pyridinforeningar - Google Patents

En ny mellanprodukt for framstellning av terapeutiskt aktiva pyridinforeningar

Info

Publication number
SE409860B
SE409860B SE7707708A SE7707708A SE409860B SE 409860 B SE409860 B SE 409860B SE 7707708 A SE7707708 A SE 7707708A SE 7707708 A SE7707708 A SE 7707708A SE 409860 B SE409860 B SE 409860B
Authority
SE
Sweden
Prior art keywords
solution
water
added
preparation
hours
Prior art date
Application number
SE7707708A
Other languages
English (en)
Swedish (sv)
Other versions
SE7707708L (sv
Inventor
P Bamberg
E Hardegger
L J S Wegh
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Priority to SE7707708A priority Critical patent/SE409860B/sv
Priority to IL54973A priority patent/IL54973A/xx
Priority to EP78900032A priority patent/EP0006864B1/en
Priority to PCT/SE1978/000010 priority patent/WO1979000024A1/en
Priority to US05/918,724 priority patent/US4216328A/en
Priority to DE19782857020 priority patent/DE2857020A1/de
Priority to CH330079A priority patent/CH642354A5/de
Priority to GB7920315A priority patent/GB2036002B/en
Priority to AU37613/78A priority patent/AU520374B2/en
Priority to DK782952A priority patent/DK295278A/da
Priority to FI782116A priority patent/FI64579C/fi
Priority to CA306,599A priority patent/CA1099725A/en
Priority to NL7807121A priority patent/NL7807121A/xx
Priority to NO782303A priority patent/NO150604C/no
Priority to IT50141/78A priority patent/IT1105249B/it
Priority to ES471365A priority patent/ES471365A1/es
Priority to IE1334/78A priority patent/IE47017B1/en
Priority to BE189041A priority patent/BE868701A/xx
Priority to AT0483678A priority patent/AT364825B/de
Priority to JP53081819A priority patent/JPS607981B2/ja
Publication of SE7707708L publication Critical patent/SE7707708L/xx
Priority to SE7905429A priority patent/SE418742B/sv
Priority to SU792800303A priority patent/SU927113A3/ru
Publication of SE409860B publication Critical patent/SE409860B/sv
Priority to AT27481A priority patent/AT366667B/de
Priority to JP57066429A priority patent/JPS609024B2/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/02—Magnesium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
SE7707708A 1977-07-04 1977-07-04 En ny mellanprodukt for framstellning av terapeutiskt aktiva pyridinforeningar SE409860B (sv)

Priority Applications (24)

Application Number Priority Date Filing Date Title
SE7707708A SE409860B (sv) 1977-07-04 1977-07-04 En ny mellanprodukt for framstellning av terapeutiskt aktiva pyridinforeningar
IL54973A IL54973A (en) 1977-07-04 1978-06-22 Process for the preparation of n,n-dimethyl(or n-methyl)-3-(p-bromophenyl)3-(3-pyridyl)allylamine and novel 3-(p-bromophenyl)-3-(3-pyridyl)3-hydroxyprop-1-ene intermediate therefor
EP78900032A EP0006864B1 (en) 1977-07-04 1978-06-26 A novel intermediate to prepare therapeutically active pyridine compounds and process for its preparation
PCT/SE1978/000010 WO1979000024A1 (en) 1977-07-04 1978-06-26 A novel intermediate for preparation of therapeutically active pyridine compounds
US05/918,724 US4216328A (en) 1977-07-04 1978-06-26 Novel intermediate for preparation of therapeutically active compounds
DE19782857020 DE2857020A1 (de) 1977-07-04 1978-06-26 A novel intermediate for preparation of therapeutically active pyridine compounds
CH330079A CH642354A5 (de) 1977-07-04 1978-06-26 Neues chemisches verbindungszwischenprodukt fuer die herstellung von therapeutisch aktiven verbindungen.
GB7920315A GB2036002B (en) 1977-07-04 1978-06-26 Intermediate for preparation of therapeutically active pyridine compounds
AU37613/78A AU520374B2 (en) 1977-07-04 1978-06-29 3-(4-bromophenyl)-3-(3-pyridyl)-3-hydroxy-prop-(1)-ene and to processes employing it
DK782952A DK295278A (da) 1977-07-04 1978-06-29 Mellemprodukt til fremstilling af terapeutisk virksomme aminer
CA306,599A CA1099725A (en) 1977-07-04 1978-06-30 3-(4-bromophenyl)-3-(3-pyridyl)-3-hydroxy-prop-(1)- ene
FI782116A FI64579C (fi) 1977-07-04 1978-06-30 Som mellanprodukt anvaendbar 3-(4-bromfenyl)-3-(3-pyridyl)-3-hydroxi-prop-(1)-en foerfarande foer framstaellning daerav oc foerfarande foer framstaellning av terapeutiskt aktiva 3 -(-bromfenyl)-3-(3-pyridyl)-allylaminderivat
NL7807121A NL7807121A (nl) 1977-07-04 1978-06-30 Tussenprodukt voor de bereiding van therapeutisch werk- zame verbindingen.
NO782303A NO150604C (no) 1977-07-04 1978-07-03 Fremgangsmaate for fremstilling av n-monometyl- og n,n-dimetyl-3-(4-bromfenyl)-3-(3-pyridyl)-allylamin samt salter og isomerer derav
IT50141/78A IT1105249B (it) 1977-07-04 1978-07-03 Procedimento per la preparazione di intermedi per la produzione di composti terapeuticamente attivi
ES471365A ES471365A1 (es) 1977-07-04 1978-07-03 Un procedimiento para la preparacion de derivados de 3-(4- bromofenil)-3-(3-piridil)-alilamina terapeuticamente activos
IE1334/78A IE47017B1 (en) 1977-07-04 1978-07-03 3-(4-bromophenyl)-3-(3-pyridyl)-3-hydroxy-prop-1-ene and its use to prepare pharmaceutically active compounds
BE189041A BE868701A (fr) 1977-07-04 1978-07-04 Nouveau produit intermediaire pour la preparation de composes therapeutiquement actifs
AT0483678A AT364825B (de) 1977-07-04 1978-07-04 Verfahren zur herstellung des neuen 3-(4-bromphenyl)-3-(3-pyridyl)-3-hydroxyprop-1-en und dessen saeureadditionssalzen
JP53081819A JPS607981B2 (ja) 1977-07-04 1978-07-04 新規な化合物およびその製法
SE7905429A SE418742B (sv) 1977-07-04 1979-06-20 Nytt forfarande for framstellning av n-metyl-(eller n,n-dimetyl)-3-4(bromfenyl)-3-(3-pyridyl)-alkylamin
SU792800303A SU927113A3 (ru) 1977-07-04 1979-08-03 Способ получени производных пиридиламина
AT27481A AT366667B (de) 1977-07-04 1981-01-23 Verfahren zur herstellung von substituierten allylaminen sowie von deren stereoisomeren, hydraten und pharmazeutisch akzeptablen salzen
JP57066429A JPS609024B2 (ja) 1977-07-04 1982-04-22 治療活性化合物の新規な製法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7707708A SE409860B (sv) 1977-07-04 1977-07-04 En ny mellanprodukt for framstellning av terapeutiskt aktiva pyridinforeningar

Publications (2)

Publication Number Publication Date
SE7707708L SE7707708L (sv) 1979-01-05
SE409860B true SE409860B (sv) 1979-09-10

Family

ID=20331765

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7707708A SE409860B (sv) 1977-07-04 1977-07-04 En ny mellanprodukt for framstellning av terapeutiskt aktiva pyridinforeningar

Country Status (20)

Country Link
US (1) US4216328A (it)
EP (1) EP0006864B1 (it)
JP (2) JPS607981B2 (it)
AT (1) AT364825B (it)
AU (1) AU520374B2 (it)
BE (1) BE868701A (it)
CA (1) CA1099725A (it)
CH (1) CH642354A5 (it)
DK (1) DK295278A (it)
ES (1) ES471365A1 (it)
FI (1) FI64579C (it)
GB (1) GB2036002B (it)
IE (1) IE47017B1 (it)
IL (1) IL54973A (it)
IT (1) IT1105249B (it)
NL (1) NL7807121A (it)
NO (1) NO150604C (it)
SE (1) SE409860B (it)
SU (1) SU927113A3 (it)
WO (1) WO1979000024A1 (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981001407A1 (en) * 1979-11-16 1981-05-28 Astra Laekemedel Ab Novel halophenyl-pyridyl-allylamine derivatives

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4036216C1 (it) * 1990-11-14 1992-01-30 Voest-Alpine Industrieanlagenbau Ges.M.B.H., Linz, At

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB850298A (en) * 1956-10-30 1960-10-05 Maggioni & C Societa Per Azion ª‡,ª‡[(p-chlorophenyl)-(4-pyridyl)] carbinols and method of preparing same
DE1468359A1 (de) * 1963-10-23 1968-11-28 Merck & Co Inc Verfahren zur Herstellung von Dibenzocycloheptehderivaten
US3396224A (en) * 1965-09-09 1968-08-06 Lilly Co Eli Controlling phytopathogenic fungi on plants with 3-pyridyl methane derivatives
US3471505A (en) * 1967-02-01 1969-10-07 Ciba Geigy Corp 1-(alkoxyphenyl)-1-(3-pyridyl)-carbinols
US3928369A (en) * 1971-04-28 1975-12-23 Haessle Ab Compounds useful as antidepressive agents, and a process for their preparation
US4094908A (en) * 1973-08-15 1978-06-13 Richter Gedeon Vegyeszeti Gyar Rt. Alpha-substituted benzhydrol derivatives
GB1480593A (en) * 1973-11-30 1977-07-20 Kefalas As Xanthene and thioxanthene derivatives having pharmaceutical activity
SE388854B (sv) * 1974-11-21 1979-03-26 Astra Laekemedel Ab Forfarande for framstellning av fenylpyridylaminderivat

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981001407A1 (en) * 1979-11-16 1981-05-28 Astra Laekemedel Ab Novel halophenyl-pyridyl-allylamine derivatives
US4418065A (en) 1979-11-16 1983-11-29 Astra Lakemedel Aktiebolag Halophenyl-pyridyl-allylamine derivatives and use

Also Published As

Publication number Publication date
IL54973A (en) 1981-12-31
EP0006864A1 (en) 1980-01-23
SE7707708L (sv) 1979-01-05
BE868701A (fr) 1979-01-04
GB2036002A (en) 1980-06-25
US4216328A (en) 1980-08-05
IL54973A0 (en) 1978-08-31
ES471365A1 (es) 1979-10-01
GB2036002B (en) 1982-04-21
ATA483678A (de) 1981-04-15
JPS57183759A (en) 1982-11-12
IE781334L (en) 1979-01-04
NO150604B (no) 1984-08-06
NO782303L (no) 1979-01-05
CH642354A5 (de) 1984-04-13
IE47017B1 (en) 1983-11-30
CA1099725A (en) 1981-04-21
JPS5414975A (en) 1979-02-03
EP0006864B1 (en) 1981-12-30
FI64579C (fi) 1983-12-12
DK295278A (da) 1979-01-05
JPS609024B2 (ja) 1985-03-07
FI782116A7 (fi) 1979-01-05
SU927113A3 (ru) 1982-05-07
FI64579B (fi) 1983-08-31
WO1979000024A1 (en) 1979-01-25
NO150604C (no) 1984-11-14
IT1105249B (it) 1985-10-28
AU3761378A (en) 1980-01-03
JPS607981B2 (ja) 1985-02-28
NL7807121A (nl) 1979-01-08
IT7850141A0 (it) 1978-07-03
AT364825B (de) 1981-11-25
AU520374B2 (en) 1982-01-28

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