SE421321B - Polymera ortoestrar och forfarande for deras framstellning - Google Patents

Polymera ortoestrar och forfarande for deras framstellning

Info

Publication number
SE421321B
SE421321B SE7703816A SE7703816A SE421321B SE 421321 B SE421321 B SE 421321B SE 7703816 A SE7703816 A SE 7703816A SE 7703816 A SE7703816 A SE 7703816A SE 421321 B SE421321 B SE 421321B
Authority
SE
Sweden
Prior art keywords
polymera
orts
procedures
production
polymera orts
Prior art date
Application number
SE7703816A
Other languages
English (en)
Swedish (sv)
Other versions
SE7703816L (sv
Inventor
R C Capozza
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of SE7703816L publication Critical patent/SE7703816L/
Publication of SE421321B publication Critical patent/SE421321B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G4/00—Condensation polymers of aldehydes or ketones with polyalcohols; Addition polymers of heterocyclic oxygen compounds containing in the ring at least once the grouping —O—C—O—
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Polyethers (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
SE7703816A 1976-04-08 1977-04-01 Polymera ortoestrar och forfarande for deras framstellning SE421321B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/675,185 US4066747A (en) 1976-04-08 1976-04-08 Polymeric orthoesters housing beneficial drug for controlled release therefrom

Publications (2)

Publication Number Publication Date
SE7703816L SE7703816L (sv) 1977-10-09
SE421321B true SE421321B (sv) 1981-12-14

Family

ID=24709398

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7703816A SE421321B (sv) 1976-04-08 1977-04-01 Polymera ortoestrar och forfarande for deras framstellning

Country Status (10)

Country Link
US (4) US4066747A (de)
JP (1) JPS52123500A (de)
AU (1) AU507701B2 (de)
CA (1) CA1112798A (de)
CH (1) CH633567A5 (de)
DE (1) DE2715502A1 (de)
FR (1) FR2347396A1 (de)
GB (1) GB1518638A (de)
IT (1) IT1082732B (de)
SE (1) SE421321B (de)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4387215A (en) * 1973-03-30 1983-06-07 Bailey William J Polycyclic ring-opened polymers
US4328204A (en) * 1977-03-02 1982-05-04 Ethicon, Inc. Absorbable polymer-drug compounds and method for making same
US4211674A (en) * 1978-04-10 1980-07-08 Polak's Frutal Works B.V. Cyclic acetals and ketals and their use in perfume compositions
US4282201A (en) * 1979-02-02 1981-08-04 Alza Corporation Pharmaceutical comprising drug and polymer
DE2928636A1 (de) * 1979-07-16 1981-02-12 Hoechst Ag Strahlungsempfindliches gemisch und verfahren zur herstellung von reliefbildern
US4425473A (en) 1980-02-04 1984-01-10 Toagosei Chemical Industry Co., Ltd. Polymerizable bicyclic orthoester compounds
US4304767A (en) * 1980-05-15 1981-12-08 Sri International Polymers of di- (and higher functionality) ketene acetals and polyols
US4322323A (en) * 1980-12-01 1982-03-30 Alza Corporation Erodible device comprising surfactant for modifying the rate of erosion of the device
US4346709A (en) * 1980-11-10 1982-08-31 Alza Corporation Drug delivery devices comprising erodible polymer and erosion rate modifier
US4489056A (en) * 1982-06-30 1984-12-18 Merck & Co., Inc. Acid anhydrides as rate controlling agent for the erosion of polymers which latter polymers have beneficial substances dispersed throughout their matrix or where the polymer matrix surrounds the beneficial substance
US4530840A (en) * 1982-07-29 1985-07-23 The Stolle Research And Development Corporation Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents
JPS6067531A (ja) * 1983-09-22 1985-04-17 Toshiba Corp 樹脂組成物
US4841968A (en) * 1986-09-26 1989-06-27 Southern Research Institute Antithrombotic/thrombolytic suture and methods of making and using the same
US4969872A (en) * 1989-03-08 1990-11-13 Alza Corporation Intravenous system for delivering a beneficial agent with delivery rate control via permeable surface area variance
US5030457A (en) * 1989-08-28 1991-07-09 Pharmaceutical Delivery Systems, Inc. Bioerodible polymers useful for the controlled release of therapeutic agents
KR920702383A (ko) * 1989-08-28 1992-09-03 원본미기재 치료제의 방출을 조절하는데 유용한 생부식성 중합체
US5620700A (en) * 1990-10-30 1997-04-15 Alza Corporation Injectable drug delivery system and method
US5461140A (en) * 1992-04-30 1995-10-24 Pharmaceutical Delivery Systems Bioerodible polymers for solid controlled release pharmaceutical compositions
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
US5912268A (en) * 1995-05-22 1999-06-15 Alza Corporation Dosage form and method for treating incontinence
US6262115B1 (en) 1995-05-22 2001-07-17 Alza Coporation Method for the management of incontinence
EP0747375A1 (de) * 1995-06-05 1996-12-11 General Electric Company Verfahren zur Herstellung von Orthoestermonomeren
US6919373B1 (en) 1996-11-12 2005-07-19 Alza Corporation Methods and devices for providing prolonged drug therapy
US20040062799A1 (en) * 1997-09-29 2004-04-01 Ayer Atul D. Therapeutic composition and delivery system for administering drug
US6486248B2 (en) 2001-01-08 2002-11-26 Milliken & Company Liquid colorant and method
US7232924B2 (en) * 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
CA2449729C (en) * 2001-06-11 2009-11-03 Xenoport, Inc. Prodrugs of gaba analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
AU2002345638A1 (en) * 2001-06-11 2002-12-23 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
US20050232995A1 (en) * 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
US20050208132A1 (en) * 2002-07-29 2005-09-22 Gayatri Sathyan Methods and dosage forms for reducing side effects of benzisozazole derivatives
US7101912B2 (en) 2002-12-06 2006-09-05 Xenoport, Inc. Carbidopa prodrugs and derivatives, and compositions and uses thereof
US20040162351A1 (en) * 2002-12-11 2004-08-19 Gallop Mark A. Orally administered dosage forms of fused GABA analog prodrugs having reduced toxicity
KR20050119676A (ko) * 2003-03-31 2005-12-21 제노포트 인코포레이티드 가바 유사체의 프로드러그를 사용한 열성 홍조의 치료 또는예방
BRPI0413756A (pt) * 2003-08-20 2006-10-31 Xenoport Inc composto, métodos para tratar ou evitar espasticidade ou um sintoma de espasticidade, doença de refluxo gastro-esofágico, vìcio em droga, vìcio em ou abuso de álcool, ou vìcio em ou abuso de nicotina, e tosse ou êmese em um paciente, e, composição farmacêutica
EP2354120A1 (de) 2003-08-20 2011-08-10 XenoPort, Inc. Synthese von Acyloxyalkylcarbamat-Prodrugs und Zwischenprodukten davon
KR20060119971A (ko) * 2003-09-11 2006-11-24 제노포트 인코포레이티드 Ｇａｂａ 유사체의 전구약물을 이용한 요실금의 치료및/또는 예방
NZ579515A (en) * 2003-09-17 2011-09-30 Xenoport Inc Treating or preventing restless legs syndrome using prodrugs of gaba analogs
US7329413B1 (en) * 2003-11-06 2008-02-12 Advanced Cardiovascular Systems, Inc. Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof
WO2005121070A1 (en) * 2004-06-04 2005-12-22 Xenoport, Inc. Levodopa prodrugs, and compositions and uses thereof
PT1751087E (pt) * 2004-06-04 2012-09-10 Xenoport Inc Derivados de levodopa e as suas composições e utilizações
US20060128676A1 (en) * 2004-07-13 2006-06-15 Pharmacofore, Inc. Compositions of nicotinic agonists and therapeutic agents and methods for treating or preventing diseases or pain
US7494985B2 (en) * 2004-11-03 2009-02-24 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
US7566738B2 (en) * 2004-11-03 2009-07-28 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
MX2007005306A (es) * 2004-11-04 2007-06-11 Xenoport Inc Formas de dosis oral de liberacion sostenida de la prodroga gabapentina.
WO2006091790A1 (en) * 2005-02-23 2006-08-31 Xenoport, Inc. Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
CN101163676A (zh) 2005-02-23 2008-04-16 普雷萨药品公司 用于治疗运动障碍及其它cns适应症的多巴胺转运蛋白抑制剂
US7351740B2 (en) 2005-06-20 2008-04-01 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use
WO2007027476A2 (en) * 2005-08-26 2007-03-08 Xenoport, Inc. Treating premature ejaculation using gabapentin and pregabalin prodrugs
US7563821B2 (en) * 2005-12-05 2009-07-21 Xenoport, Inc. Levodopa prodrug mesylate, compositions thereof, and uses thereof
MX2008014794A (es) 2006-05-26 2009-04-08 Pharmacofore Inc Liberacion controlada de opioides fenolicos.
WO2008005371A2 (en) * 2006-06-29 2008-01-10 Medtronic, Inc. Poly(orthoester) polymers, and methods of making and using same
WO2008027557A2 (en) * 2006-08-31 2008-03-06 Spherics, Inc. Topiramate compositions and methods of enhancing its bioavailability
US7585996B2 (en) * 2006-09-15 2009-09-08 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
US7740699B2 (en) * 2006-10-05 2010-06-22 E.I. Du Pont De Nemours And Company Orthoformate-protected polyols
US8298576B2 (en) 2006-11-17 2012-10-30 Supernus Pharmaceuticals, Inc. Sustained-release formulations of topiramate
US20080161393A1 (en) * 2006-12-08 2008-07-03 Barrett Ronald W Use of prodrugs of GABA analogs for treating disease
WO2008079387A1 (en) * 2006-12-21 2008-07-03 Xenoport, Inc. Catechol protected levodopa diester prodrugs, compositions, and methods of use
CA2673336A1 (en) 2006-12-21 2008-06-26 Xenoport, Inc. Levodopa dimethyl-substituted diester prodrugs, compositions, and methods of use
US8940315B2 (en) * 2008-04-18 2015-01-27 Medtronic, Inc. Benzodiazepine formulation in a polyorthoester carrier
US8956642B2 (en) * 2008-04-18 2015-02-17 Medtronic, Inc. Bupivacaine formulation in a polyorthoester carrier
US9290445B2 (en) * 2008-10-20 2016-03-22 Xenoport, Inc. Methods of synthesizing a levodopa ester prodrug
US8399513B2 (en) * 2008-10-20 2013-03-19 Xenoport, Inc. Levodopa prodrug mesylate hydrate
WO2011028234A1 (en) * 2009-09-04 2011-03-10 Xenoport, Inc. Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
WO2011056240A2 (en) 2009-11-09 2011-05-12 Xenoport, Inc. Pharmaceutical compositions and oral dosage forms of a levodopa prodrug and methods of use
WO2011091164A1 (en) * 2010-01-22 2011-07-28 Xenoport, Inc. Oral dosage forms having a high loading of a tranexamic acid prodrug
DK2621282T3 (da) 2010-09-28 2020-05-04 Univ California Gaba-agonister i behandlingen af forstyrrelser forbundet med metabolisk syndrom og gaba-kombinationer i behandling eller profylakse af type i diabetes
AU2016332071B2 (en) 2015-10-01 2019-04-18 Elysium Therapeutics, Inc. Polysubunit opioid prodrugs resistant to overdose and abuse
US10335406B2 (en) 2015-10-01 2019-07-02 Elysium Therapeutics, Inc. Opioid compositions resistant to overdose and abuse
EP3595663A4 (de) 2017-03-17 2021-01-13 Elysium Therapeutics, Inc. Mehrfachuntereinheit-opioid-prodrugs mit resistenz gegen überdosierung und missbrauch

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2636884A (en) * 1953-04-28 J-moxoeane
US3328427A (en) * 1963-10-31 1967-06-27 Celanese Corp Mono, ortho and oxetane esters of trimethylol compounds
DE1592655C2 (de) * 1966-07-13 1972-03-30 Gewerkschaft Victor, Chemische Werke, 4620 Castrop Rauxel Düngemittelgranulat mit kontollierter Nährstoffabgabe
US4015970A (en) * 1968-09-06 1977-04-05 Airwick Industries, Inc. Granular products for soil treatment
US3887699A (en) * 1969-03-24 1975-06-03 Seymour Yolles Biodegradable polymeric article for dispensing drugs
US3696123A (en) * 1970-03-19 1972-10-03 Siegfried H Schroeter Dihydrocarbonoxyoxethanes
US3673216A (en) * 1970-05-01 1972-06-27 Gen Electric Alkoxyoxetanes
US3914402A (en) * 1973-06-14 1975-10-21 Alza Corp Ophthalmic dosage form, for releasing medication over time
US3911098A (en) * 1974-02-11 1975-10-07 American Cyanamid Co Medicament carrier

Also Published As

Publication number Publication date
AU2393377A (en) 1978-10-12
JPS52123500A (en) 1977-10-17
US4155740A (en) 1979-05-22
US4136252A (en) 1979-01-23
US4119579A (en) 1978-10-10
GB1518638A (en) 1978-07-19
CA1112798A (en) 1981-11-17
SE7703816L (sv) 1977-10-09
US4066747A (en) 1978-01-03
IT1082732B (it) 1985-05-21
FR2347396A1 (fr) 1977-11-04
DE2715502C2 (de) 1988-01-28
DE2715502A1 (de) 1977-10-20
JPS619968B2 (de) 1986-03-27
CH633567A5 (de) 1982-12-15
FR2347396B1 (de) 1980-12-12
AU507701B2 (en) 1980-02-21

Similar Documents

Publication Publication Date Title
SE421321B (sv) Polymera ortoestrar och forfarande for deras framstellning
IT1106424B (it) Agenti antielmintici e procedimenti per la loro produzione
IT1091303B (it) Fenossi-ammino-propanoli e procedimento per la loro produzione
FI53560C (fi) Foerfarande och anordning foer upprullning av materialbanor
SE430517B (sv) Elektrolysforfarande och elektrolysror
SE7611169L (sv) Kinazolinoner och forfarande for framstellning derav
SE7700398L (sv) Antracyklinderivat och forfarande for framstellning derav
SE7701728L (sv) Klusterforeningar och forfarande for framstellning derav
SE7709942L (sv) Uracilderivat och forfarande for framstellning derav
SE7508642L (sv) 7-metoxi-6-tia-tetracykliner och forfarande for framstellning derav
SE7710805L (sv) Fenylalaninderivat och forfarande for framstellning derav
FI773104A7 (fi) Foerfarande och anordning foer framstaellning av fibrer av termoplastiskt material
SE7706824L (sv) B-laktamantibiotika och forfarande for framstellning derav
SE7705873L (sv) Bensensulfonykarbamider och forfarande for deras framstellning
SE7805437L (sv) Poly(organofosfazener) och forfarande for framstellning derav
SE7705086L (sv) 1,2,6-tiadiazinon och forfarande for framstellning derav
SE7706269L (sv) Uracilderivat och forfarande for framstellning derav
FI772840A7 (fi) Foerfarande och komposition foer aostadkommande av polyuretanskum
SE7614386L (sv) Bensamider och forfarande for framstellning derav
SE7602849L (sv) D-homosteroider och forfarande for framstellning derav
SE7713720L (sv) Ergolinderivat och forfarande for framstellning derav
FI772953A7 (fi) Foerfarande och anordning foer vaermeformning av kontinuerliga laosorganrader av plastmonofilament
FI773577A7 (fi) Foerfarande och anordning foer framstaellning av planglas
SE7712725L (sv) Kinolonderivat och forfarande for framstellning derav
SE7706724L (sv) Alkinoler och forfarande for framstellning derav

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7703816-4

Effective date: 19941110

Format of ref document f/p: F