SE456136B - Forfarande for framstellning av en med ett lipofilt biologiskt aktivt emne bemengd berare pa basis av rekonstituerat ldl (lagdensitetslipoprotein) - Google Patents

Forfarande for framstellning av en med ett lipofilt biologiskt aktivt emne bemengd berare pa basis av rekonstituerat ldl (lagdensitetslipoprotein)

Info

Publication number
SE456136B
SE456136B SE8502998A SE8502998A SE456136B SE 456136 B SE456136 B SE 456136B SE 8502998 A SE8502998 A SE 8502998A SE 8502998 A SE8502998 A SE 8502998A SE 456136 B SE456136 B SE 456136B
Authority
SE
Sweden
Prior art keywords
ldl
active substance
biologically active
solvent
mixture
Prior art date
Application number
SE8502998A
Other languages
English (en)
Swedish (sv)
Other versions
SE8502998L (sv
SE8502998D0 (sv
Inventor
M Masquelier
C Peterson
M Ros
M Rudling
S Vitols
Original Assignee
Oncholab Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncholab Ab filed Critical Oncholab Ab
Priority to SE8502998A priority Critical patent/SE456136B/sv
Publication of SE8502998D0 publication Critical patent/SE8502998D0/xx
Priority to JP61503451A priority patent/JPS62502549A/ja
Priority to US07/030,861 priority patent/US4868158A/en
Priority to AU59968/86A priority patent/AU583402B2/en
Priority to PCT/SE1986/000291 priority patent/WO1986007540A1/en
Priority to EP86903706A priority patent/EP0229100B1/en
Priority to DE8686903706T priority patent/DE3681578D1/de
Priority to AT86903706T priority patent/ATE67412T1/de
Publication of SE8502998L publication Critical patent/SE8502998L/
Priority to NO870545A priority patent/NO169048C/no
Priority to FI870644A priority patent/FI86802C/fi
Priority to DK077787A priority patent/DK168785B1/da
Publication of SE456136B publication Critical patent/SE456136B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1275—Lipoproteins or protein-free species thereof, e.g. chylomicrons; Artificial high-density lipoproteins [HDL], low-density lipoproteins [LDL] or very-low-density lipoproteins [VLDL]; Precursors thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SE8502998A 1985-06-17 1985-06-17 Forfarande for framstellning av en med ett lipofilt biologiskt aktivt emne bemengd berare pa basis av rekonstituerat ldl (lagdensitetslipoprotein) SE456136B (sv)

Priority Applications (11)

Application Number Priority Date Filing Date Title
SE8502998A SE456136B (sv) 1985-06-17 1985-06-17 Forfarande for framstellning av en med ett lipofilt biologiskt aktivt emne bemengd berare pa basis av rekonstituerat ldl (lagdensitetslipoprotein)
AT86903706T ATE67412T1 (de) 1985-06-17 1986-06-17 Verfahren zur herstellung eines makromolekularen, mit einer biologisch aktiven substanz beladenen traegers, der so erhaltene gegenstand und seine verwendung.
PCT/SE1986/000291 WO1986007540A1 (en) 1985-06-17 1986-06-17 Method for the preparation of a macromolecular carrier loaded with a biologically active substance, product thus obtained and use thereof
US07/030,861 US4868158A (en) 1985-06-17 1986-06-17 Method for the production of a macromolecular carrier loaded with a biologically active substance
AU59968/86A AU583402B2 (en) 1985-06-17 1986-06-17 Method for the production of a macromolecular carrier loaded with a biologically active substance
JP61503451A JPS62502549A (ja) 1985-06-17 1986-06-17 生物学的活性物質を担持する巨大分子担体の製造方法
EP86903706A EP0229100B1 (en) 1985-06-17 1986-06-17 Method for the preparation of a macromolecular carrier loaded with a biologically active substance, product thus obtained and use thereof
DE8686903706T DE3681578D1 (de) 1985-06-17 1986-06-17 Verfahren zur herstellung eines makromolekularen, mit einer biologisch aktiven substanz beladenen traegers, der so erhaltene gegenstand und seine verwendung.
NO870545A NO169048C (no) 1985-06-17 1987-02-11 Fremgangsmaate for fremstilling av en makromolekylaer baererfylt med en lipofil biologisk aktiv substans
FI870644A FI86802C (fi) 1985-06-17 1987-02-16 Foerfarande foer framstaellning av en makromolekylbaerare belastad med biologiskt aktivt aemne
DK077787A DK168785B1 (da) 1985-06-17 1987-02-16 Fremgangsmåde til fremstilling af en bærer ladet med lipofilt biologisk aktivt stof på basis af rekonstitueret LDL

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8502998A SE456136B (sv) 1985-06-17 1985-06-17 Forfarande for framstellning av en med ett lipofilt biologiskt aktivt emne bemengd berare pa basis av rekonstituerat ldl (lagdensitetslipoprotein)

Publications (3)

Publication Number Publication Date
SE8502998D0 SE8502998D0 (sv) 1985-06-17
SE8502998L SE8502998L (sv) 1986-12-18
SE456136B true SE456136B (sv) 1988-09-12

Family

ID=20360603

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8502998A SE456136B (sv) 1985-06-17 1985-06-17 Forfarande for framstellning av en med ett lipofilt biologiskt aktivt emne bemengd berare pa basis av rekonstituerat ldl (lagdensitetslipoprotein)

Country Status (11)

Country Link
US (1) US4868158A (da)
EP (1) EP0229100B1 (da)
JP (1) JPS62502549A (da)
AT (1) ATE67412T1 (da)
AU (1) AU583402B2 (da)
DE (1) DE3681578D1 (da)
DK (1) DK168785B1 (da)
FI (1) FI86802C (da)
NO (1) NO169048C (da)
SE (1) SE456136B (da)
WO (1) WO1986007540A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2609399A1 (fr) * 1987-01-13 1988-07-15 Ire Celltarg Sa Procede d'incorporation d'un ou plusieurs principes actifs lipophiles dans des lipoproteines, lipoproteines obtenues et composition pharmaceutique les contenant
FR2664500B1 (fr) * 1990-07-13 1994-10-28 Lille Ii Universite Droit Sant Procede de preparation d'une lipoproteine modifiee par incorporation d'une substance active lipophile, lipoproteine modifiee ainsi obtenue et composition pharmaceutique ou cosmetique la contenant.
EP0611306B1 (en) * 1991-11-08 1998-07-08 Somatogen, Inc. Hemoglobins as drug delivery agents
WO1993020800A1 (en) * 1992-04-08 1993-10-28 Paavo Kai Johannes Kinnunen Composition for therapeutic or diagnostic use, process for its preparation and its use
AU690592B2 (en) * 1993-11-08 1998-04-30 Peptide Delivery Systems Pty Ltd Labelled diagnostic compositions and methods of their use
US5756067A (en) * 1993-11-08 1998-05-26 Peptide Delivery Systems Pty Ltd Labelled diagnostic compositions and method of their use
US5652339A (en) * 1993-12-31 1997-07-29 Rotkreuzstiftung Zentrallaboratorium Method of producing reconstituted lipoproteins
CA2259179C (en) * 1996-07-03 2008-09-23 University Of Pittsburgh Emulsion formulations for hydrophilic active agents
AUPP032097A0 (en) * 1997-11-11 1997-12-04 Peptide Delivery Systems Pty Ltd Improved labelled diagnostic compositions and methods of their use
US6514523B1 (en) 2000-02-14 2003-02-04 Ottawa Heart Institute Research Corporation Carrier particles for drug delivery and process for preparation
US20090110739A1 (en) * 2007-05-15 2009-04-30 University Of North Texas Health Science Center At Forth Worth Targeted cancer chemotherapy using synthetic nanoparticles
US8734853B2 (en) 2008-11-17 2014-05-27 University Of North Texas Health Science Center At Fort Worth HDL particles for delivery of nucleic acids
US20160346219A1 (en) 2015-06-01 2016-12-01 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
US12194157B2 (en) 2020-04-09 2025-01-14 Finncure Oy Carrier for targeted delivery to a host
FI20215508A1 (en) 2020-04-09 2021-10-10 Niemelae Erik Johan Mimetic nanoparticles to prevent the spread of new coronaviruses and reduce the rate of infection

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ180199A (en) * 1976-03-04 1978-11-13 New Zealand Dev Finance Method of testing for the presence of elevated plasma liprotein concentration
US4186192A (en) * 1978-12-18 1980-01-29 Cutter Laboratories, Inc. Stabilized immune serum globulin
US4440679A (en) * 1980-03-05 1984-04-03 Cutter Laboratories, Inc. Pasteurized therapeutically active protein compositions
US4356117A (en) * 1980-10-23 1982-10-26 U.S. Govt., Dept. Of Health & Human Services Chemical modifications of proteins which induce new receptor specificities and therefore elicit new effects in cells
JPS5967228A (ja) * 1982-10-07 1984-04-16 Green Cross Corp:The 寒冷不溶性グロブリンの凍結乾燥方法
US4478829A (en) * 1983-04-28 1984-10-23 Armour Pharmaceutical Company Pharmaceutical preparation containing purified fibronectin
NZ208241A (en) * 1984-05-22 1987-09-30 John Stephen Ayers Purification of blood plasma or serum: selective removal of (very) low density lipoproteins (ldl and vldl)
AU6408586A (en) * 1985-10-03 1987-04-24 Biotechnology Research Partners Limited Novel lipoprotein-based drug-delivery systems

Also Published As

Publication number Publication date
SE8502998L (sv) 1986-12-18
NO870545D0 (no) 1987-02-11
FI870644A0 (fi) 1987-02-16
WO1986007540A1 (en) 1986-12-31
SE8502998D0 (sv) 1985-06-17
NO870545L (no) 1987-02-11
DK77787A (da) 1987-02-16
DE3681578D1 (de) 1991-10-24
FI86802C (fi) 1992-10-26
DK168785B1 (da) 1994-06-13
EP0229100B1 (en) 1991-09-18
ATE67412T1 (de) 1991-10-15
JPS62502549A (ja) 1987-10-01
FI86802B (fi) 1992-07-15
AU5996886A (en) 1987-01-13
AU583402B2 (en) 1989-04-27
US4868158A (en) 1989-09-19
NO169048C (no) 1992-05-06
EP0229100A1 (en) 1987-07-22
FI870644A7 (fi) 1987-02-16
NO169048B (no) 1992-01-27
DK77787D0 (da) 1987-02-16
JPH0586935B2 (da) 1993-12-14

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