SE500702C2 - Sätt och anordning för optisk analys av prov separerade i tunna kapillärer - Google Patents
Sätt och anordning för optisk analys av prov separerade i tunna kapillärerInfo
- Publication number
- SE500702C2 SE500702C2 SE9201089A SE9201089A SE500702C2 SE 500702 C2 SE500702 C2 SE 500702C2 SE 9201089 A SE9201089 A SE 9201089A SE 9201089 A SE9201089 A SE 9201089A SE 500702 C2 SE500702 C2 SE 500702C2
- Authority
- SE
- Sweden
- Prior art keywords
- capillary
- separation
- detector
- sample components
- components
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
- G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/74—Optical detectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6052—Construction of the column body
- G01N30/6082—Construction of the column body transparent to radiation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Electrochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Control And Other Processes For Unpacking Of Materials (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9201089A SE500702C2 (sv) | 1992-04-07 | 1992-04-07 | Sätt och anordning för optisk analys av prov separerade i tunna kapillärer |
| AT93908259T ATE172030T1 (de) | 1992-04-07 | 1993-04-07 | Verfahren und detektor für trennungsprozesse |
| JP05517383A JP3127238B2 (ja) | 1992-04-07 | 1993-04-07 | 分離プロセスのための方法および検出器 |
| PCT/SE1993/000305 WO1993020435A1 (en) | 1992-04-07 | 1993-04-07 | Method and detector for separation processes |
| DE69321480T DE69321480T2 (de) | 1992-04-07 | 1993-04-07 | Verfahren und detektor für trennungsprozesse |
| US08/313,319 US5627643A (en) | 1992-04-07 | 1993-04-07 | Method and detector for separation processes |
| EP93908259A EP0666982B1 (de) | 1992-04-07 | 1993-04-07 | Verfahren und detektor für trennungsprozesse |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9201089A SE500702C2 (sv) | 1992-04-07 | 1992-04-07 | Sätt och anordning för optisk analys av prov separerade i tunna kapillärer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE9201089D0 SE9201089D0 (sv) | 1992-04-07 |
| SE9201089L SE9201089L (sv) | 1993-10-08 |
| SE500702C2 true SE500702C2 (sv) | 1994-08-15 |
Family
ID=20385875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9201089A SE500702C2 (sv) | 1992-04-07 | 1992-04-07 | Sätt och anordning för optisk analys av prov separerade i tunna kapillärer |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5627643A (de) |
| EP (1) | EP0666982B1 (de) |
| JP (1) | JP3127238B2 (de) |
| AT (1) | ATE172030T1 (de) |
| DE (1) | DE69321480T2 (de) |
| SE (1) | SE500702C2 (de) |
| WO (1) | WO1993020435A1 (de) |
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| US6017434A (en) | 1995-05-09 | 2000-01-25 | Curagen Corporation | Apparatus and method for the generation, separation, detection, and recognition of biopolymer fragments |
| US6485625B1 (en) | 1995-05-09 | 2002-11-26 | Curagen Corporation | Apparatus and method for the generation, separation, detection, and recognition of biopolymer fragments |
| US5942443A (en) * | 1996-06-28 | 1999-08-24 | Caliper Technologies Corporation | High throughput screening assay systems in microscale fluidic devices |
| US6429025B1 (en) * | 1996-06-28 | 2002-08-06 | Caliper Technologies Corp. | High-throughput screening assay systems in microscale fluidic devices |
| US5871628A (en) * | 1996-08-22 | 1999-02-16 | The University Of Texas System | Automatic sequencer/genotyper having extended spectral response |
| JP3077609B2 (ja) * | 1996-10-31 | 2000-08-14 | 株式会社島津製作所 | マイクロチップ電気泳動方法及び装置 |
| JP2001504235A (ja) * | 1997-03-14 | 2001-03-27 | トランスジエノミツク・インコーポレーテツド | ポリヌクレオチド分離のバンド列の表示 |
| AU2021099A (en) * | 1997-12-30 | 1999-07-19 | Caliper Technologies Corporation | Software for the display of chromatographic separation data |
| US6335201B1 (en) * | 1998-03-06 | 2002-01-01 | The Regents Of The University Of California | Method and apparatus for detecting enzymatic activity using molecules that change electrophoretic mobility |
| US6156576A (en) * | 1998-03-06 | 2000-12-05 | The Regents Of The University Of California | Fast controllable laser lysis of cells for analysis |
| US6740497B2 (en) * | 1998-03-06 | 2004-05-25 | The Regents Of The University Of California | Method and apparatus for detecting cancerous cells using molecules that change electrophoretic mobility |
| US6096205A (en) * | 1998-05-13 | 2000-08-01 | The Regents Of The University Of California | Hand portable thin-layer chromatography system |
| US6818437B1 (en) | 1998-05-16 | 2004-11-16 | Applera Corporation | Instrument for monitoring polymerase chain reaction of DNA |
| US7498164B2 (en) | 1998-05-16 | 2009-03-03 | Applied Biosystems, Llc | Instrument for monitoring nucleic acid sequence amplification reaction |
| ATE425448T1 (de) | 1998-05-16 | 2009-03-15 | Applera Corp | Optisches gerät insbesondere zur überwachung von dns-polymerasekettenreaktionen |
| US6529835B1 (en) | 1998-06-25 | 2003-03-04 | Caliper Technologies Corp. | High throughput methods, systems and apparatus for performing cell based screening assays |
| US7155344B1 (en) | 1998-07-27 | 2006-12-26 | Caliper Life Sciences, Inc. | Distributed database for analytical instruments |
| US6498497B1 (en) * | 1998-10-14 | 2002-12-24 | Caliper Technologies Corp. | Microfluidic controller and detector system with self-calibration |
| EP1081596A4 (de) | 1999-03-26 | 2008-04-23 | Sony Corp | Vorrichtung und verfahren zur dateiverwaltung, datenaufzeichnung und - wiedergabe |
| JP2000283960A (ja) * | 1999-03-31 | 2000-10-13 | Shimadzu Corp | マイクロチップ電気泳動装置 |
| US6353475B1 (en) | 1999-07-12 | 2002-03-05 | Caliper Technologies Corp. | Light source power modulation for use with chemical and biochemical analysis |
| JP2001033427A (ja) * | 1999-07-16 | 2001-02-09 | Hitachi Software Eng Co Ltd | 電気泳動方法及び電気泳動装置 |
| US6888951B1 (en) | 1999-08-23 | 2005-05-03 | Nagaoka & Co., Ltd. | Methods and apparatus for analyzing operational and analyte data acquired from optical disc |
| US6556923B2 (en) | 2000-01-26 | 2003-04-29 | Caliper Technologies Corp. | Software for high throughput microfluidic systems |
| GB0019500D0 (en) * | 2000-08-08 | 2000-09-27 | Diamond Optical Tech Ltd | System and method |
| GB0019499D0 (en) * | 2000-08-08 | 2000-09-27 | Diamond Optical Tech Ltd | system and method |
| GB0019496D0 (en) * | 2000-08-08 | 2000-09-27 | Diamond Optical Tech Ltd | System and method |
| US7033475B2 (en) * | 2000-10-25 | 2006-04-25 | Shimadzu Corporation | Electrophoretic apparatus |
| WO2002044695A1 (en) * | 2000-11-16 | 2002-06-06 | Burstein Technologies, Inc. | Methods and apparatus for detecting and quantifying lymphocytes with optical biodiscs |
| US20020172980A1 (en) * | 2000-11-27 | 2002-11-21 | Phan Brigitte Chau | Methods for decreasing non-specific binding of beads in dual bead assays including related optical biodiscs and disc drive systems |
| US20040248093A1 (en) * | 2000-11-27 | 2004-12-09 | Coombs James Howard | Magneto-optical bio-discs and systems including related methods |
| US20030003464A1 (en) * | 2000-11-27 | 2003-01-02 | Phan Brigitte C. | Dual bead assays including optical biodiscs and methods relating thereto |
| US6800438B2 (en) * | 2000-12-28 | 2004-10-05 | Xerox Corporation | Imager for DNA sequencer |
| US6942773B1 (en) | 2001-01-26 | 2005-09-13 | The Regents Of The University Of California | Particle sizer and DNA sequencer |
| CA2453390A1 (en) | 2001-07-25 | 2003-02-06 | Applera Corporation | Time-delay integration in electrophoretic detection systems |
| US7265833B2 (en) * | 2001-07-25 | 2007-09-04 | Applera Corporation | Electrophoretic system with multi-notch filter and laser excitation source |
| US7280207B2 (en) | 2001-07-25 | 2007-10-09 | Applera Corporation | Time-delay integration in a flow cytometry system |
| US20030129665A1 (en) * | 2001-08-30 | 2003-07-10 | Selvan Gowri Pyapali | Methods for qualitative and quantitative analysis of cells and related optical bio-disc systems |
| WO2003021222A2 (en) * | 2001-08-31 | 2003-03-13 | Burstein Technologies, Inc. | Capture layer assemblies for cellular assays including related optical analysis discs and methods |
| EP1423699A4 (de) * | 2001-09-07 | 2006-01-18 | Burstein Technologies Inc | Auf zellkernmorphologie beruhende identifizierung und quantifizierung weisser blutzelltypen unter verwendung optischer bio-disc-systeme |
| CA2468041A1 (en) * | 2001-11-20 | 2003-05-30 | Burstein Technologies, Inc. | Optical bio-discs and microfluidic devices for analysis of cells |
| US7179357B2 (en) * | 2002-10-25 | 2007-02-20 | Beckman Coulter, Inc. | Serial sample injection in capillary electrophoresis |
| WO2004087882A2 (en) * | 2003-03-26 | 2004-10-14 | Washington University | Neuregulin protein regulation of synaptic proteins |
| US20040204866A1 (en) * | 2003-04-09 | 2004-10-14 | Allington Robert W. | Method and apparatus to enhance the signal to noise ratio in chromatography |
| US6909091B2 (en) | 2003-05-30 | 2005-06-21 | Nanosep Ab | Separation and analysis of sample components |
| IL160869A0 (en) * | 2004-03-15 | 2004-08-31 | Dnr Imaging System Ltd | Integrated system for real time gel electrophoresis running and documenting |
| TWI251079B (en) * | 2004-06-15 | 2006-03-11 | Univ Nat Cheng Kung | Inspection chip and the manufacturing method thereof |
| US7846676B2 (en) | 2004-07-19 | 2010-12-07 | Cell Biosciences, Inc. | Methods and devices for analyte detection |
| US7935479B2 (en) | 2004-07-19 | 2011-05-03 | Cell Biosciences, Inc. | Methods and devices for analyte detection |
| FR2879293B1 (fr) * | 2004-12-13 | 2007-04-06 | Total France Sa | Procede pour l'analyse de la composition en hydrocarbures de produits petroliers liquides. |
| FR2880426B1 (fr) * | 2004-12-30 | 2007-04-06 | Total France Sa | Procede et dispositif pour la determination du point de fumee des hydrocarbures |
| CN100394172C (zh) * | 2005-01-25 | 2008-06-11 | 中国科学院化学研究所 | 显微毛细管电泳仪 |
| US8945361B2 (en) * | 2005-09-20 | 2015-02-03 | ProteinSimple | Electrophoresis standards, methods and kits |
| EP2049233A4 (de) | 2006-07-10 | 2011-08-31 | Convergent Bioscience Ltd | Verfahren und vorrichtung zur präzisen auswahl und extraktion einer fokussierten komponente bei der in mikrokanälen durchgeführten isolelektrischen fokussierung |
| US10107782B2 (en) * | 2008-01-25 | 2018-10-23 | ProteinSimple | Method to perform limited two dimensional separation of proteins and other biologicals |
| WO2010141131A1 (en) | 2009-06-04 | 2010-12-09 | Lockheed Martin Corporation | Multiple-sample microfluidic chip for dna analysis |
| US9280726B2 (en) | 2009-12-18 | 2016-03-08 | Fpinnovation | On-line macrocontaminant analyser and method |
| GB2497501A (en) | 2010-10-15 | 2013-06-12 | Lockheed Corp | Micro fluidic optic design |
| US9322054B2 (en) | 2012-02-22 | 2016-04-26 | Lockheed Martin Corporation | Microfluidic cartridge |
| CN102879365A (zh) * | 2012-09-21 | 2013-01-16 | 常州大学 | 一种毛细管电泳荧光检测装置 |
| US10031104B2 (en) * | 2014-06-13 | 2018-07-24 | Yes Way Intellectual Holdings, Llc | Mobile micro-lab for chemical analysis of fluids |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1800993A1 (de) * | 1968-10-03 | 1970-05-27 | Max Planck Gesellschaft | Verfahren zur automatisierten elektronischen densitometrischen Auswertung von mit Hilfe der sogenannten traegerfreien Elektrophorese getrennten Stoffgemischen |
| US4420383A (en) * | 1980-07-10 | 1983-12-13 | Olympus Optical Co., Ltd. | Fractionating method in electrophoreses |
| JPS6093339A (ja) * | 1983-10-27 | 1985-05-25 | Olympus Optical Co Ltd | 電気泳動装置 |
| SE455646B (sv) * | 1984-10-22 | 1988-07-25 | Radians Innova Ab | Fluorescensanordning |
| JPH065227B2 (ja) * | 1985-02-27 | 1994-01-19 | オリンパス光学工業株式会社 | 電気泳動装置による総蛋白値の定量方法 |
| GB8513538D0 (en) * | 1985-05-29 | 1985-07-03 | Mackay C D | Electrophoresis |
| JP2762451B2 (ja) * | 1988-03-31 | 1998-06-04 | アイシン精機株式会社 | 遺伝子物質の電気泳動パターン分析装置 |
| DE3812899A1 (de) * | 1988-04-18 | 1989-10-26 | Wilfried Heil | Elektronische kamera zur dokumentation von fluoreszenzmustern auf elektrophoresegelen |
| US4927265A (en) * | 1988-04-29 | 1990-05-22 | 501 Microphoretic Systems, Inc. | Detector for fluorescence and absorption spectroscopy |
| US5006210A (en) * | 1989-02-06 | 1991-04-09 | Iowa State University Research Foundation, Inc. | Means and method for capillary zone electrophoresis with laser-induced indirect fluorescence detection |
| US5141609A (en) * | 1990-11-16 | 1992-08-25 | The Trustees Of The Leland Stanford Junior University | Method and device employing time-delayed integration for detecting sample components after separation |
| US5162654A (en) * | 1991-02-01 | 1992-11-10 | Wisconsin Alumni Research Foundation | Detection apparatus for electrophoretic gels |
| US5098536A (en) * | 1991-02-01 | 1992-03-24 | Beckman Instruments, Inc. | Method of improving signal-to-noise in electropherogram |
| JPH0552810A (ja) * | 1991-08-27 | 1993-03-02 | Hitachi Ltd | 電気泳動装置 |
| JP2815506B2 (ja) * | 1992-04-14 | 1998-10-27 | 株式会社日立製作所 | 光検出型電気泳動装置 |
-
1992
- 1992-04-07 SE SE9201089A patent/SE500702C2/sv not_active IP Right Cessation
-
1993
- 1993-04-07 US US08/313,319 patent/US5627643A/en not_active Expired - Lifetime
- 1993-04-07 DE DE69321480T patent/DE69321480T2/de not_active Expired - Fee Related
- 1993-04-07 AT AT93908259T patent/ATE172030T1/de not_active IP Right Cessation
- 1993-04-07 WO PCT/SE1993/000305 patent/WO1993020435A1/en not_active Ceased
- 1993-04-07 EP EP93908259A patent/EP0666982B1/de not_active Expired - Lifetime
- 1993-04-07 JP JP05517383A patent/JP3127238B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0666982A1 (de) | 1995-08-16 |
| EP0666982B1 (de) | 1998-10-07 |
| SE9201089D0 (sv) | 1992-04-07 |
| JPH07505471A (ja) | 1995-06-15 |
| DE69321480T2 (de) | 1999-05-27 |
| US5627643A (en) | 1997-05-06 |
| DE69321480D1 (de) | 1998-11-12 |
| JP3127238B2 (ja) | 2001-01-22 |
| WO1993020435A1 (en) | 1993-10-14 |
| SE9201089L (sv) | 1993-10-08 |
| ATE172030T1 (de) | 1998-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |