SE503122C2 - Användning av en inositoltrisfosfatester för behandling av inflammatoriska tillstånd - Google Patents

Användning av en inositoltrisfosfatester för behandling av inflammatoriska tillstånd

Info

Publication number
SE503122C2
SE503122C2 SE9303854A SE9303854A SE503122C2 SE 503122 C2 SE503122 C2 SE 503122C2 SE 9303854 A SE9303854 A SE 9303854A SE 9303854 A SE9303854 A SE 9303854A SE 503122 C2 SE503122 C2 SE 503122C2
Authority
SE
Sweden
Prior art keywords
trisphosphate
inositol
myo
tri
ester
Prior art date
Application number
SE9303854A
Other languages
English (en)
Swedish (sv)
Other versions
SE9303854L (sv
SE9303854D0 (sv
Inventor
Lars Persson
Nicola Rehnberg
Torgny Gustafsson
Original Assignee
Perstorp Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perstorp Ab filed Critical Perstorp Ab
Priority to SE9303854A priority Critical patent/SE503122C2/sv
Publication of SE9303854D0 publication Critical patent/SE9303854D0/xx
Priority to PCT/SE1994/001095 priority patent/WO1995014477A1/en
Priority to EP95901676A priority patent/EP0730460B1/de
Priority to AU10817/95A priority patent/AU1081795A/en
Priority to DE69430813T priority patent/DE69430813T2/de
Priority to DK95901676T priority patent/DK0730460T3/da
Priority to JP51499395A priority patent/JP4172045B2/ja
Priority to US08/640,785 priority patent/US5866557A/en
Priority to AT95901676T priority patent/ATE218871T1/de
Priority to ES95901676T priority patent/ES2177620T3/es
Publication of SE9303854L publication Critical patent/SE9303854L/
Publication of SE503122C2 publication Critical patent/SE503122C2/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
SE9303854A 1993-11-22 1993-11-22 Användning av en inositoltrisfosfatester för behandling av inflammatoriska tillstånd SE503122C2 (sv)

Priority Applications (10)

Application Number Priority Date Filing Date Title
SE9303854A SE503122C2 (sv) 1993-11-22 1993-11-22 Användning av en inositoltrisfosfatester för behandling av inflammatoriska tillstånd
ES95901676T ES2177620T3 (es) 1993-11-22 1994-11-18 Utilizacion de un ester inositotrifosfato para el tratamiento de transtornos inflamatorios.
DE69430813T DE69430813T2 (de) 1993-11-22 1994-11-18 Verwendung eines inositoltriphosphatesters zur behandlung von entzündungen
EP95901676A EP0730460B1 (de) 1993-11-22 1994-11-18 Verwendung eines inositoltriphosphatesters zur behandlung von entzündungen
AU10817/95A AU1081795A (en) 1993-11-22 1994-11-18 The use of an ester of inositoltrisphosphate for the treatment of inflammatory conditions
PCT/SE1994/001095 WO1995014477A1 (en) 1993-11-22 1994-11-18 The use of an ester of inositoltrisphosphate for the treatment of inflammatory conditions
DK95901676T DK0730460T3 (da) 1993-11-22 1994-11-18 Anvendelsen af en ester af inositoltriphosphat til behandlingen af betændelsestilstande
JP51499395A JP4172045B2 (ja) 1993-11-22 1994-11-18 イノシトール三燐酸エステルを使用した炎症性障害治療用薬剤
US08/640,785 US5866557A (en) 1993-11-22 1994-11-18 Use of an ester of inositoltrisphosphate for the treatment of inflammatory conditions
AT95901676T ATE218871T1 (de) 1993-11-22 1994-11-18 Verwendung eines inositoltriphosphatesters zur behandlung von entzündungen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9303854A SE503122C2 (sv) 1993-11-22 1993-11-22 Användning av en inositoltrisfosfatester för behandling av inflammatoriska tillstånd

Publications (3)

Publication Number Publication Date
SE9303854D0 SE9303854D0 (sv) 1993-11-22
SE9303854L SE9303854L (sv) 1995-05-23
SE503122C2 true SE503122C2 (sv) 1996-03-25

Family

ID=20391829

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9303854A SE503122C2 (sv) 1993-11-22 1993-11-22 Användning av en inositoltrisfosfatester för behandling av inflammatoriska tillstånd

Country Status (10)

Country Link
US (1) US5866557A (de)
EP (1) EP0730460B1 (de)
JP (1) JP4172045B2 (de)
AT (1) ATE218871T1 (de)
AU (1) AU1081795A (de)
DE (1) DE69430813T2 (de)
DK (1) DK0730460T3 (de)
ES (1) ES2177620T3 (de)
SE (1) SE503122C2 (de)
WO (1) WO1995014477A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9600194D0 (sv) * 1996-01-19 1996-01-19 Perstorp Ab A new chemical compound
ES2383673T3 (es) * 2000-09-22 2012-06-25 Jpi Commercial, Llc Composiciones de gamma-hidroxibutirato que contienen portadores de hidrato de carbonos
JP2004518639A (ja) 2000-11-21 2004-06-24 イノロジック， インコーポレイテッド 塩化物分泌を増加しそして炎症を阻害するためのイノシトール誘導体
FR2828206B1 (fr) * 2001-08-03 2004-09-24 Centre Nat Rech Scient Utilisation d'inhibiteurs des lysyl oxydases pour la culture cellulaire et le genie tissulaire
CA2488230C (en) * 2002-04-29 2013-04-09 Yves Claude Nicolau Inositol pyrophosphates, and methods of use thereof
FI20021570A0 (fi) * 2002-09-03 2002-09-03 Gallen Kallela Siren Janne Päällystetyn kirurgisen stentin paranneltu rakenne
EP2039683B1 (de) * 2002-10-03 2012-12-19 Targegen, Inc. Vasculo-statisches Mittel und Anwendungsverfahren dafür
US20050250694A1 (en) * 2003-10-10 2005-11-10 Ma Jian-Xing Compounds useful in inhibiting vascular leakage, inflammation and fibrosis and methods of making and using same
US20050130897A1 (en) * 2003-12-11 2005-06-16 Ma Jian-Xing Compounds useful in inhibiting vascular leakage, inflammation and fibrosis and methods of making and using same
US7745423B2 (en) * 2004-07-06 2010-06-29 NormOxys, Inc Calcium/sodium salt of inositol tripyrophosphate as an allosteric effector of hemoglobin
US20060258626A1 (en) * 2004-07-06 2006-11-16 Claude Nicolau Use of inositol-tripyrophosphate in treating tumors and diseases
US20060106000A1 (en) * 2004-07-06 2006-05-18 Claude Nicolau Use of inositol-tripyrophosphate in treating tumors and diseases
JP5028405B2 (ja) * 2005-03-18 2012-09-19 ノームオクシス インコーポレイテッド ヘモグロビンのアロステリックエフェクターとしてのミオイノシトール１，６：２，３：４，５トリピロリン酸のカルシウム塩
CA2674048A1 (en) * 2006-12-29 2008-07-10 Normoxys, Inc. Cyclitols and their derivatives and their therapeutic applications
CA2688233A1 (en) * 2007-05-01 2008-11-06 Normoxys, Inc. Erythropoietin complementation or replacement
US20080287341A1 (en) * 2007-05-18 2008-11-20 Danyang Chen Treatment of vascular abnormalities using nanoparticles

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515722A (en) * 1982-03-30 1985-05-07 Merck & Co., Inc. Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents
SE465951B (sv) * 1984-10-23 1991-11-25 Perstorp Ab Isomer av inositoltrifosfat foeretraedesvis i saltform foer anvaendning som terapeutiskt eller profylaktiskt medel samt kompositioner daerav
SE8605063D0 (sv) * 1986-11-26 1986-11-26 Matti Siren Derivatives of cyclohexane
SE464059C (sv) * 1988-09-15 1997-06-02 Perstorp Ab Användning av inositoltrifosfat för framställning av läkemedel
CA2019878A1 (en) * 1989-09-13 1991-03-13 Robert Sabin Method of treatment of rheumatoid arthritis using phytic acid
SE8904355D0 (sv) * 1989-12-21 1989-12-21 Perstorp Ab Medicament

Also Published As

Publication number Publication date
EP0730460A1 (de) 1996-09-11
EP0730460B1 (de) 2002-06-12
US5866557A (en) 1999-02-02
ES2177620T3 (es) 2002-12-16
WO1995014477A1 (en) 1995-06-01
DE69430813T2 (de) 2003-01-30
JP4172045B2 (ja) 2008-10-29
DE69430813D1 (de) 2002-07-18
AU1081795A (en) 1995-06-13
DK0730460T3 (da) 2002-09-23
SE9303854L (sv) 1995-05-23
ATE218871T1 (de) 2002-06-15
JPH09505581A (ja) 1997-06-03
SE9303854D0 (sv) 1993-11-22

Similar Documents

Publication Publication Date Title
JP4172045B2 (ja) イノシトール三燐酸エステルを使用した炎症性障害治療用薬剤
US5003098A (en) Method of reducing or eliminating adverse effects of a pharmaceutical composition or a drug
US4357324A (en) Prodrug derivatives of 9β-D-arabinofuranosyl-2-fluoroadenine
US5015634A (en) Method of treating tissue damage with inositol triphosphate
US4066678A (en) 3-trihydroxygermyl propionic acid and its salts and a process for the production thereof
EP0536269B1 (de) Verwendung von inosittriphosphat zur zubereitung von medikamenten
CN111770756B (zh) 非天然氨基酸类衍生物、包含其的药物组合物及其制备方法和用途
AU2003231157A1 (en) Inositol pyrophosphates, and methods of use thereof
WO2018028494A1 (zh) 吉西他滨ProTide乏氧活化前药及其应用
JP2547257B2 (ja) イノシトールトリホスフェートを含有する組織の損傷に対する医薬
EP2834254A2 (de) Moenomycin-analoga, syntheseverfahren und verwendung
CN108368137B (zh) 用于艰难梭状芽胞杆菌感染的4,6-二(邻硫代磷酸盐)-肌醇-1,2,3,5-四-邻硫酸盐
SE502989C2 (sv) Användning av en inositoltrisfosfatester för beredning av läkemedel
MX2011001800A (es) Compuestos de arsenico organico y metodos para el tratamiento de cancer.
US20100144676A1 (en) Oleyl phosphocholine
SE502990C2 (sv) Användning av en inositoltrisfosfatester för beredning av ett smärtstillande läkemedel
US20240158431A1 (en) Compositions and compounds for co-delivery of uridine and ketoleucine
US4129660A (en) Derivatives of cis-epoxy-1,2-propyl-phosphonic acid and drugs containing in particular as active ingredients derivatives of cis-epoxy-1,2-propylphosphonic acid in dextrorotatory form
KR100249408B1 (ko) (s)-2,3-디하이드로폴리프레놀,(s)-2,3-디하이드로폴리프레닐모노포스-페이트,이들의제조방법및이들을포함한암의성장또는전이억제용약제
US3309270A (en) Organic phosphorus anthelmintics and method of using the same
FI61893C (fi) Foerfarande foer framstaellning av antiinflammatoriska fenylbutazon-enolesterderivat
CN108864114A (zh) 选择性a2a受体拮抗剂
SE470511B (sv) Användning av inositolreisfosfat för beredning av läkemedel
SE510914C2 (sv) Användning av en ester av inositoltrisfosfat för beredning av läkemedel
WO2001077121A1 (en) Gold complexes

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 9303854-5

Format of ref document f/p: F