SE510305C2 - Nytt salt - Google Patents

Nytt salt

Info

Publication number
SE510305C2
SE510305C2 SE9702066A SE9702066A SE510305C2 SE 510305 C2 SE510305 C2 SE 510305C2 SE 9702066 A SE9702066 A SE 9702066A SE 9702066 A SE9702066 A SE 9702066A SE 510305 C2 SE510305 C2 SE 510305C2
Authority
SE
Sweden
Prior art keywords
salt
tartrate
benzopyran
dihydro
fluoro
Prior art date
Application number
SE9702066A
Other languages
English (en)
Swedish (sv)
Other versions
SE9702066D0 (sv
SE9702066L (sv
Inventor
Haakan Nykvist
Daniel Sohn
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9702066A priority Critical patent/SE510305C2/sv
Publication of SE9702066D0 publication Critical patent/SE9702066D0/xx
Priority to TW087107397A priority patent/TW510899B/zh
Priority to YU62499A priority patent/YU62499A/sh
Priority to HU0001878A priority patent/HUP0001878A3/hu
Priority to HK00104934.1A priority patent/HK1025575B/en
Priority to PT98925993T priority patent/PT984952E/pt
Priority to PL98337181A priority patent/PL337181A1/xx
Priority to KR19997011107A priority patent/KR20010013127A/ko
Priority to IDW991407A priority patent/ID23794A/id
Priority to RU99128026/04A priority patent/RU2193560C2/ru
Priority to EP98925993A priority patent/EP0984952B1/fr
Priority to TR1999/02926T priority patent/TR199902926T2/xx
Priority to SI9830332T priority patent/SI0984952T1/xx
Priority to SK1594-99A priority patent/SK282755B6/sk
Priority to BR9809519-6A priority patent/BR9809519A/pt
Priority to PCT/SE1998/000907 priority patent/WO1998054166A1/fr
Priority to DK98925993T priority patent/DK0984952T3/da
Priority to CNB988056631A priority patent/CN1198814C/zh
Priority to DE69809547T priority patent/DE69809547T2/de
Priority to JP50056099A priority patent/JP3554338B2/ja
Priority to CA002291732A priority patent/CA2291732C/fr
Priority to US09/077,718 priority patent/US6858645B2/en
Priority to EEP199900549A priority patent/EE03874B1/xx
Priority to IL13323498A priority patent/IL133234A/en
Priority to NZ501075A priority patent/NZ501075A/en
Priority to ES98925993T priority patent/ES2187030T3/es
Priority to UA99127241A priority patent/UA53720C2/uk
Priority to AU77923/98A priority patent/AU729301B2/en
Priority to AT98925993T priority patent/ATE228121T1/de
Priority to ARP980102434A priority patent/AR012751A1/es
Priority to ZA984486A priority patent/ZA984486B/xx
Priority to MYPI98002400A priority patent/MY117960A/en
Publication of SE9702066L publication Critical patent/SE9702066L/xx
Publication of SE510305C2 publication Critical patent/SE510305C2/sv
Priority to IS5270A priority patent/IS1943B/is
Priority to NO995853A priority patent/NO995853L/no
Priority to BG103949A priority patent/BG64051B1/bg
Priority to US10/964,388 priority patent/US20050085532A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
SE9702066A 1997-05-30 1997-05-30 Nytt salt SE510305C2 (sv)

Priority Applications (36)

Application Number Priority Date Filing Date Title
SE9702066A SE510305C2 (sv) 1997-05-30 1997-05-30 Nytt salt
TW087107397A TW510899B (en) 1997-05-30 1998-05-13 A salt (R)-3-N,N-dicyclobutyamino-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide hydrogen (2R,3R)-tartrate, a pharmaceutical composition containing said salt and a process for the manufacture of said salt
CA002291732A CA2291732C (fr) 1997-05-30 1998-05-15 Sel (r)-3-n,n-dicyclobutylamino-8-fluoro-3,4-dihydro-2h-1-benzopyran-5-carboxaminde hydrogen (2r,3r)-tartrate
JP50056099A JP3554338B2 (ja) 1997-05-30 1998-05-15 新規な塩
HU0001878A HUP0001878A3 (en) 1997-05-30 1998-05-15 (r)-3-(n,n-dicyclobutyl-amino)-8-fluoro-3,4-dihydro-2h-1-benzopyran-5-carboxamide hydrogen tartrate, process for its preparation and pharmatceutical compositions of the same
HK00104934.1A HK1025575B (en) 1997-05-30 1998-05-15 A new salt
PT98925993T PT984952E (pt) 1997-05-30 1998-05-15 Novo sal
PL98337181A PL337181A1 (en) 1997-05-30 1998-05-15 Novel salt
KR19997011107A KR20010013127A (ko) 1997-05-30 1998-05-15 신규 염
IDW991407A ID23794A (id) 1997-05-30 1998-05-15 Proses, pembuatan dan penggunaan garam bentuk (2r, 3r) tartrat
RU99128026/04A RU2193560C2 (ru) 1997-05-30 1998-05-15 Новая соль
EP98925993A EP0984952B1 (fr) 1997-05-30 1998-05-15 Nouveau sel
TR1999/02926T TR199902926T2 (xx) 1997-05-30 1998-05-15 Yeni bir tuz.
SI9830332T SI0984952T1 (en) 1997-05-30 1998-05-15 A new salt
SK1594-99A SK282755B6 (sk) 1997-05-30 1998-05-15 Soľ karboxamidhydrogenvínan, spôsob jej prípravy, farmaceutický prípravok s jej obsahom a jej použitie
BR9809519-6A BR9809519A (pt) 1997-05-30 1998-05-15 Sal, processo para fabricação e uso do mesmo, formulação farmacêutica, e, processo para prevenção ou tratamento de distúrbios cns e perturbações médicas relacionadas
PCT/SE1998/000907 WO1998054166A1 (fr) 1997-05-30 1998-05-15 Nouveau sel
DK98925993T DK0984952T3 (da) 1997-05-30 1998-05-15 Hidtil ukendt salt
CNB988056631A CN1198814C (zh) 1997-05-30 1998-05-15 一种新的盐
YU62499A YU62499A (sh) 1997-05-30 1998-05-15 Nova so
DE69809547T DE69809547T2 (de) 1997-05-30 1998-05-15 Neues salz
AT98925993T ATE228121T1 (de) 1997-05-30 1998-05-15 Neues salz
US09/077,718 US6858645B2 (en) 1997-05-30 1998-05-15 Tartrate salts of (R) -3-N,N- dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1- benzopyran-5-carboxamide
EEP199900549A EE03874B1 (et) 1997-05-30 1998-05-15 (R)-3-N,N-ditsüklobutüülamino-8-fluoro-3,4-dihüdro-2H-1-bensopüraan-5-karboksam iidvesinik- tartraat, selle valmistamise meetod ja seda sisaldav ravimkoostis
IL13323498A IL133234A (en) 1997-05-30 1998-05-15 Hydrogen Tartrate of (R) - 3 (N, N-Dicyclobutyl-Amino) - 8 Fluoro-4,3 Dihydro 1 H2-Benzopyran-5-Carboxamide, process for its preparation and pharmaceutical preparations containing it
NZ501075A NZ501075A (en) 1997-05-30 1998-05-15 (R)-3-N,N-dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide hydrogen (2R,3R)-tartrate
ES98925993T ES2187030T3 (es) 1997-05-30 1998-05-15 Una nueva sal.
UA99127241A UA53720C2 (uk) 1997-05-30 1998-05-15 Кислий (2r,3r)-тартрат (r)-3-n,n-дициклоаміно-8-фтор-3,4-дигідро-2н-1-бензопіран-5-карбоксаміду, його моногідрат, спосіб їх одержання та фармацевтична композиція
AU77923/98A AU729301B2 (en) 1997-05-30 1998-05-15 A new salt
ZA984486A ZA984486B (en) 1997-05-30 1998-05-26 A new salt
ARP980102434A AR012751A1 (es) 1997-05-30 1998-05-26 Sales de hidrogeno tartrato de (r) -3-n,n-diciclobutilamino-8-fluoro-3,4 -dihidro-2h-1-benzopiran-5-carboxamida, su uso para la fabricacion de medicamentos para tratar trastornos de snc y trastornos medicos relacionados y procedimiento para la fabricacion de dichas sales
MYPI98002400A MY117960A (en) 1997-05-30 1998-05-29 A new salt
IS5270A IS1943B (is) 1997-05-30 1999-11-24 (R)-3-N,N-dísýklóbútýlamínó-8-flúor-3,4-díhýdró-2H-1-bensópýran-5-karboxamíðhýdrógentartrat, aðferðvið framleiðslu þess og lyfjablöndur sem innihalda það
NO995853A NO995853L (no) 1997-05-30 1999-11-29 Nytt salt
BG103949A BG64051B1 (bg) 1997-05-30 1999-12-03 Нова сол
US10/964,388 US20050085532A1 (en) 1997-05-30 2004-10-12 Tartrate salts of (R)-3-N,N-dicyclo-butylamino-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9702066A SE510305C2 (sv) 1997-05-30 1997-05-30 Nytt salt

Publications (3)

Publication Number Publication Date
SE9702066D0 SE9702066D0 (sv) 1997-05-30
SE9702066L SE9702066L (sv) 1998-12-01
SE510305C2 true SE510305C2 (sv) 1999-05-10

Family

ID=20407187

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9702066A SE510305C2 (sv) 1997-05-30 1997-05-30 Nytt salt

Country Status (33)

Country Link
US (2) US6858645B2 (fr)
EP (1) EP0984952B1 (fr)
JP (1) JP3554338B2 (fr)
KR (1) KR20010013127A (fr)
CN (1) CN1198814C (fr)
AR (1) AR012751A1 (fr)
AT (1) ATE228121T1 (fr)
AU (1) AU729301B2 (fr)
BG (1) BG64051B1 (fr)
BR (1) BR9809519A (fr)
CA (1) CA2291732C (fr)
DE (1) DE69809547T2 (fr)
DK (1) DK0984952T3 (fr)
EE (1) EE03874B1 (fr)
ES (1) ES2187030T3 (fr)
HU (1) HUP0001878A3 (fr)
ID (1) ID23794A (fr)
IL (1) IL133234A (fr)
IS (1) IS1943B (fr)
MY (1) MY117960A (fr)
NO (1) NO995853L (fr)
NZ (1) NZ501075A (fr)
PL (1) PL337181A1 (fr)
PT (1) PT984952E (fr)
RU (1) RU2193560C2 (fr)
SE (1) SE510305C2 (fr)
SK (1) SK282755B6 (fr)
TR (1) TR199902926T2 (fr)
TW (1) TW510899B (fr)
UA (1) UA53720C2 (fr)
WO (1) WO1998054166A1 (fr)
YU (1) YU62499A (fr)
ZA (1) ZA984486B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0102886D0 (sv) * 2001-08-29 2001-08-29 Astrazeneca Ab New formulation
SE0102887D0 (sv) * 2001-08-29 2001-08-29 Astrazeneca Ab New formulation
SE0102888D0 (sv) * 2001-08-29 2001-08-29 Astrazeneca Ab New formulation
JP2006500366A (ja) * 2002-08-15 2006-01-05 ワイス 温度調節機能障害の治療ための５ＨＴ２ａ受容体の拮抗
SE0301796D0 (sv) * 2003-06-19 2003-06-19 Astrazeneca Ab New use II
SE0301795D0 (sv) * 2003-06-19 2003-06-19 Astrazeneca Ab New use I
ATE528807T1 (de) * 2006-05-11 2011-10-15 Johnson Controls Saft Advanced Power Solutions Llc Modulares batteriesystem
JP5163931B2 (ja) * 2007-03-08 2013-03-13 株式会社リコー 定着装置及び画像形成装置
EP2065385A1 (fr) * 2007-11-28 2009-06-03 Laboratorios SALVAT, S.A. Sel cristallin stable de (R)-3-fluorophenyl-3,4,5-trifluorobenzylcarbamic acid 1-azabiciyclo [2.2.2]oct-3-yl ester
CN103833713B (zh) * 2008-11-28 2016-02-03 中国医学科学院药物研究所 硝克柳胺化合物晶iii型、其制法和其药物组合物与用途
US9637479B2 (en) * 2013-04-26 2017-05-02 Sanofi Tartrate salt of 5-chloro-thiophene-2-carboxylic acid [(S)-2-[2-methyl-3-(2-oxo-pyrrolidin-1-yl)-benzenesulfonylamino]-3-(4-methyl-piperazin-1-yl)-3-oxo-propyl]amide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU611976B2 (en) * 1987-12-24 1991-06-27 John Wyeth & Brother Limited Aroyl urea and carbamic acid derivatives of azabicyclo compounds
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
US5420151A (en) 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
RU2047614C1 (ru) * 1992-06-15 1995-11-10 Джон Вайс энд Бразер Лимитед Гетероциклические соединения, или их фармацевтически приемлемые аддитивные соли кислоты, или n-оксид гетероциклического соединения, или его аддитивная соль кислоты
US5990114A (en) * 1996-02-28 1999-11-23 Recordati, S.A., Chemical And Pharmaceutical Company Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence
IT1282705B1 (it) 1996-02-28 1998-03-31 Recordati Chem Pharm Uso di antagonisti del recettore serotoninergico 5-ht|a per il trattamento dell'incontinenza urinaria

Also Published As

Publication number Publication date
AU7792398A (en) 1998-12-30
ID23794A (id) 2000-05-11
CA2291732C (fr) 2003-12-30
BG103949A (en) 2000-07-31
MY117960A (en) 2004-08-30
DE69809547T2 (de) 2003-08-21
NZ501075A (en) 2001-08-31
US20050085532A1 (en) 2005-04-21
BR9809519A (pt) 2000-06-20
CA2291732A1 (fr) 1998-12-03
TW510899B (en) 2002-11-21
ES2187030T3 (es) 2003-05-16
AU729301B2 (en) 2001-02-01
CN1258290A (zh) 2000-06-28
HUP0001878A3 (en) 2002-04-29
DK0984952T3 (da) 2003-02-24
TR199902926T2 (xx) 2000-03-21
ZA984486B (en) 1998-11-30
IL133234A (en) 2004-05-12
PL337181A1 (en) 2000-08-14
KR20010013127A (ko) 2001-02-26
DE69809547D1 (de) 2003-01-02
EE03874B1 (et) 2002-10-15
EP0984952B1 (fr) 2002-11-20
IS5270A (is) 1999-11-24
EE9900549A (et) 2000-06-15
US6858645B2 (en) 2005-02-22
IL133234A0 (en) 2001-03-19
SK282755B6 (sk) 2002-12-03
PT984952E (pt) 2003-03-31
JP2002501527A (ja) 2002-01-15
BG64051B1 (bg) 2003-11-28
JP3554338B2 (ja) 2004-08-18
AR012751A1 (es) 2000-11-08
HUP0001878A2 (hu) 2001-05-28
EP0984952A1 (fr) 2000-03-15
RU2193560C2 (ru) 2002-11-27
SK159499A3 (en) 2000-10-09
SE9702066D0 (sv) 1997-05-30
UA53720C2 (uk) 2003-02-17
ATE228121T1 (de) 2002-12-15
SE9702066L (sv) 1998-12-01
IS1943B (is) 2004-08-13
YU62499A (sh) 2002-06-19
NO995853D0 (no) 1999-11-29
US20030109576A1 (en) 2003-06-12
NO995853L (no) 2000-01-31
WO1998054166A1 (fr) 1998-12-03
CN1198814C (zh) 2005-04-27
HK1025575A1 (en) 2000-11-17

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