SE512958C2 - Kolesterolsänkande komposition innehållande beta-sitosterol och/eller beta-sitostanol samt förfarande för dess framställning - Google Patents

Kolesterolsänkande komposition innehållande beta-sitosterol och/eller beta-sitostanol samt förfarande för dess framställning

Info

Publication number
SE512958C2
SE512958C2 SE9801536A SE9801536A SE512958C2 SE 512958 C2 SE512958 C2 SE 512958C2 SE 9801536 A SE9801536 A SE 9801536A SE 9801536 A SE9801536 A SE 9801536A SE 512958 C2 SE512958 C2 SE 512958C2
Authority
SE
Sweden
Prior art keywords
composition according
cholesterol
solution
component
organic phase
Prior art date
Application number
SE9801536A
Other languages
English (en)
Swedish (sv)
Other versions
SE9801536L (sv
SE9801536D0 (sv
Inventor
Kjell Sjoeberg
Sergej Bolkhovets
Original Assignee
Triple Crown Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20411164&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE512958(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Publication of SE9801536D0 publication Critical patent/SE9801536D0/xx
Priority to SE9801536A priority Critical patent/SE512958C2/sv
Application filed by Triple Crown Ab filed Critical Triple Crown Ab
Priority to AU43035/99A priority patent/AU4303599A/en
Priority to PCT/SE1999/000721 priority patent/WO1999056729A1/fr
Priority to US09/509,281 priority patent/US6491952B1/en
Priority to DK99948541T priority patent/DK1009385T4/da
Priority to EP99948541A priority patent/EP1009385B2/fr
Priority to AT99948541T priority patent/ATE244557T1/de
Priority to DE69909413T priority patent/DE69909413T3/de
Publication of SE9801536L publication Critical patent/SE9801536L/xx
Publication of SE512958C2 publication Critical patent/SE512958C2/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G1/00—Cocoa; Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/30—Cocoa products, e.g. chocolate; Substitutes therefor
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/14—Organic oxygen compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
    • A23D7/005—Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
    • A23D7/0056—Spread compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G1/00—Cocoa; Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/30—Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/32—Cocoa products, e.g. chocolate; Substitutes therefor characterised by the composition containing organic or inorganic compounds
    • A23G1/42—Cocoa products, e.g. chocolate; Substitutes therefor characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G1/426—Cocoa products, e.g. chocolate; Substitutes therefor characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing vitamins or antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G1/00—Cocoa; Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/30—Cocoa products, e.g. chocolate; Substitutes therefor
    • A23G1/56—Liquid products; Solid products in the form of powders, flakes or granules for making liquid products, e.g. for making chocolate milk, drinks and the products for their preparation, pastes for spreading or milk crumb
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G2200/00—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G2200/00—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
    • A23G2200/04—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents containing vitamins, antibiotics, other medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Confectionery (AREA)
  • Edible Oils And Fats (AREA)
SE9801536A 1998-04-30 1998-04-30 Kolesterolsänkande komposition innehållande beta-sitosterol och/eller beta-sitostanol samt förfarande för dess framställning SE512958C2 (sv)

Priority Applications (8)

Application Number Priority Date Filing Date Title
SE9801536A SE512958C2 (sv) 1998-04-30 1998-04-30 Kolesterolsänkande komposition innehållande beta-sitosterol och/eller beta-sitostanol samt förfarande för dess framställning
DE69909413T DE69909413T3 (de) 1998-04-30 1999-04-30 Zusammensetzung zur senkung des cholesterinspiegels
AU43035/99A AU4303599A (en) 1998-04-30 1999-04-30 Cholesterol lowering composition
AT99948541T ATE244557T1 (de) 1998-04-30 1999-04-30 Zusammensetzung zur senkung des cholesterinspiegels
PCT/SE1999/000721 WO1999056729A1 (fr) 1998-04-30 1999-04-30 Composition hypocholesterolemiante
US09/509,281 US6491952B1 (en) 1998-04-30 1999-04-30 Cholesterol lowering composition
DK99948541T DK1009385T4 (da) 1998-04-30 1999-04-30 Sammensætning til sænkning af kolesterolniveau
EP99948541A EP1009385B2 (fr) 1998-04-30 1999-04-30 Composition hypocholesterolemiante

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9801536A SE512958C2 (sv) 1998-04-30 1998-04-30 Kolesterolsänkande komposition innehållande beta-sitosterol och/eller beta-sitostanol samt förfarande för dess framställning

Publications (3)

Publication Number Publication Date
SE9801536D0 SE9801536D0 (sv) 1998-04-30
SE9801536L SE9801536L (sv) 1999-10-31
SE512958C2 true SE512958C2 (sv) 2000-06-12

Family

ID=20411164

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9801536A SE512958C2 (sv) 1998-04-30 1998-04-30 Kolesterolsänkande komposition innehållande beta-sitosterol och/eller beta-sitostanol samt förfarande för dess framställning

Country Status (8)

Country Link
US (1) US6491952B1 (fr)
EP (1) EP1009385B2 (fr)
AT (1) ATE244557T1 (fr)
AU (1) AU4303599A (fr)
DE (1) DE69909413T3 (fr)
DK (1) DK1009385T4 (fr)
SE (1) SE512958C2 (fr)
WO (1) WO1999056729A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106061290A (zh) * 2014-03-03 2016-10-26 拉伊西奥营养有限公司 降低血清胆固醇的食用产品

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US6123978A (en) * 1998-08-31 2000-09-26 Mcneil-Ppc, Inc. Stable salad dressings
US6376481B2 (en) 1998-09-02 2002-04-23 Mcneil-Ppc, Inc. Sterol esters in tableted solid dosage forms
US6242001B1 (en) * 1998-11-30 2001-06-05 Mcneil-Ppc, Inc. Method for producing dispersible sterol and stanol compounds
ES2235979T3 (es) * 1999-11-03 2005-07-16 Forbes Medi-Tech Inc. Composiciones que comprenden aceites o grasas comestibles asi como fitosteroles y/o fitostanoles disueltos.
US6677327B1 (en) 1999-11-24 2004-01-13 Archer-Daniels-Midland Company Phytosterol and phytostanol compositions
US6610320B2 (en) 2000-04-14 2003-08-26 Mars, Incorporated Compositions and methods for improving vascular health
US7144595B2 (en) * 2001-11-16 2006-12-05 Brandeis University Prepared foods containing triglyceride-recrystallized non-esterified phytosterols
US6623780B1 (en) 2002-03-26 2003-09-23 Cargill, Inc. Aqueous dispersible sterol product
JP4773720B2 (ja) 2002-06-12 2011-09-14 ザ・コカ−コーラ・カンパニー 植物ステロール含有飲料
US7306819B2 (en) 2002-06-12 2007-12-11 The Coca-Cola Company Beverages containing plant sterols
WO2004014141A1 (fr) * 2002-07-26 2004-02-19 Unilever N.V. Phytosterols ou phytostanols et leur utilisation dans des produits alimentaires
US7329429B2 (en) * 2003-09-25 2008-02-12 Chimel Mark J Bars and confectioneries containing cocoa solids having a high cocoa polyphenol content and sterol/stanol esters and processes for their preparation
US20050181049A1 (en) * 2003-11-19 2005-08-18 Dong Liang C. Composition and method for enhancing bioavailability
DE602005010972D1 (de) * 2004-01-30 2008-12-24 Unilever Nv Teilchenförmiges produkt, das phytosterole enthält, sowie nahrungsmittelzusammensetzungen, die dieses weissmittel enthalten
US20060035009A1 (en) 2004-08-10 2006-02-16 Kraft Foods Holdings, Inc. Compositions and processes for water-dispersible phytosterols and phytostanols
US20070026126A1 (en) * 2005-08-01 2007-02-01 Bryan Hitchcock Sterol fortified beverages
US7575768B2 (en) * 2005-09-07 2009-08-18 Brandeis University Dietary supplements and prepared foods containing triglyceride-recrystallized non-esterified phytosterols
US7601380B2 (en) * 2005-11-17 2009-10-13 Pepsico, Inc. Beverage clouding system and method
SE532965C2 (sv) 2008-02-06 2010-05-25 Edio Healthcare Ab Förfarande för framställning av mikropartiklar innehållande växtsterol
WO2012038226A1 (fr) 2010-09-22 2012-03-29 Unilever Nv Pâtes à tartiner continues de matière grasse alimentaire
US8039025B1 (en) 2010-10-15 2011-10-18 Life Plus, LLC Methods and dosage forms for the treatment of human cancers
US9132117B2 (en) 2013-06-17 2015-09-15 Kgk Synergize, Inc Compositions and methods for glycemic control of subjects with impaired fasting glucose
FI125947B (en) 2013-07-05 2016-04-29 Ravintoraisio Oy Blood cholesterol lowering composition
US11369895B2 (en) * 2017-01-20 2022-06-28 Nutech Ventures Nanoporous starch aerogels impregnated with phytosterols and methods of preparing the nanoporous starch aerogels

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ZA72698B (en) 1972-02-03 1973-09-26 Liebenberg R W Method of preparing medicinal compositions
US3881005A (en) 1973-08-13 1975-04-29 Lilly Co Eli Pharmaceutical dispersible powder of sitosterols and a method for the preparation thereof
US4218334A (en) † 1975-06-06 1980-08-19 Henkel Corporation Phytosterol blends
JPS62126966A (ja) * 1985-11-27 1987-06-09 Nisshin Oil Mills Ltd:The 改良されたインスタントパウダ−組成物
DE3829643A1 (de) 1988-09-01 1990-03-15 Roecar Holdings Nv Phyto- und zoosterole und deren derivate mit verbesserter wasserloeslichkeit
DE4038385C2 (de) 1990-12-01 1998-09-17 Hoyer Gmbh & Co Kg Sitosterol und seine Glykoside mit verbesserter Bioverfügbarkeit
US5244887A (en) 1992-02-14 1993-09-14 Straub Carl D Stanols to reduce cholesterol absorption from foods and methods of preparation and use thereof
CA2091152C (fr) † 1993-03-05 2005-05-03 Kirsten Westesen Particules lipidiques solides, particules d'agents bioactifs, et methode de preparation et d'utilisation
JPH06329588A (ja) † 1993-05-19 1994-11-29 Riken Vitamin Co Ltd 水分散性モノグリセリド
US6423363B1 (en) † 1997-08-22 2002-07-23 Lipton, Division Of Conopco, Inc. Aqueous dispersion
ES2222553T3 (es) † 1997-08-22 2005-02-01 Unilever N.V. Producto alimenticio a base de grasa que comprende esteroles.
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FI109327B (fi) * 1998-02-27 2002-07-15 Spice Sciences Oy Menetelmä seerumin kokonais- ja LDL-kolestrolipitoisuutta alentavan beta-sitosterolin rasvamaisen seoksen valmistamiseksi
BR9904796B1 (pt) * 1998-03-24 2012-02-22 composição de óleo ou gordura contendo fitosterol, composição de óleo ou gordura, produto alimentar, produto de bebida, e óleo de mesa de cozimento.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106061290A (zh) * 2014-03-03 2016-10-26 拉伊西奥营养有限公司 降低血清胆固醇的食用产品

Also Published As

Publication number Publication date
DK1009385T4 (da) 2007-04-23
EP1009385B2 (fr) 2007-01-03
WO1999056729A1 (fr) 1999-11-11
EP1009385A2 (fr) 2000-06-21
SE9801536L (sv) 1999-10-31
SE9801536D0 (sv) 1998-04-30
DE69909413T3 (de) 2007-08-16
US6491952B1 (en) 2002-12-10
AU4303599A (en) 1999-11-23
WO1999056729B1 (fr) 1999-12-09
EP1009385B1 (fr) 2003-07-09
DK1009385T3 (da) 2003-11-03
DE69909413D1 (de) 2003-08-14
DE69909413T2 (de) 2004-06-09
ATE244557T1 (de) 2003-07-15

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