SE513814C2 - Anordning för behandling av sjukdomar med elektriska fält - Google Patents

Anordning för behandling av sjukdomar med elektriska fält

Info

Publication number: SE513814C2
Authority: SE; Sweden
Prior art keywords: electrodes; tissue; treatment; impedance; voltage
Prior art date: 1998-03-31

Application number

SE9801139A

Other languages

English (en)

Swedish (sv)

Other versions

SE9801139D0 (sv

SE9801139L (sv

Inventor

Bertil Persson

Bernt Boehmer

Bo Thorvinger

Original Assignee

Aditus Medical Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-31

Filing date

1998-03-31

Publication date

2000-11-06

1998-03-31 Application filed by Aditus Medical Ab filed Critical Aditus Medical Ab

1998-03-31 Priority to SE9801139A priority Critical patent/SE513814C2/sv

1998-03-31 Publication of SE9801139D0 publication Critical patent/SE9801139D0/xx

1999-03-30 Priority to JP2000543197A priority patent/JP2002511320A/ja

1999-03-30 Priority to PCT/SE1999/000511 priority patent/WO1999052589A1/en

1999-03-30 Priority to EP99918408A priority patent/EP1067985B1/de

1999-03-30 Priority to AT99918408T priority patent/ATE309839T1/de

1999-03-30 Priority to DE69928383T priority patent/DE69928383T2/de

1999-03-30 Priority to AU36338/99A priority patent/AU741329B2/en

1999-03-30 Priority to CA002325476A priority patent/CA2325476A1/en

1999-10-01 Publication of SE9801139L publication Critical patent/SE9801139L/xx

2000-11-06 Publication of SE513814C2 publication Critical patent/SE513814C2/sv

2005-08-15 Priority to US11/204,258 priority patent/US20060015147A1/en

2007-01-22 Priority to US11/656,549 priority patent/US20070118069A1/en

2011-06-24 Priority to US13/168,350 priority patent/US20120029508A1/en

Links

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/044—Shape of the electrode
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/0436—Material of the electrode
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0502—Skin piercing electrodes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/323—Interference currents, i.e. treatment by several currents summed in the body
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Radiology & Medical Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Electrotherapy Devices (AREA)
Surgical Instruments (AREA)
Control Of Eletrric Generators (AREA)
Control Of Motors That Do Not Use Commutators (AREA)

SE9801139A 1998-03-31 1998-03-31 Anordning för behandling av sjukdomar med elektriska fält SE513814C2 (sv)

Priority Applications (11)

Application Number	Priority Date	Filing Date	Title
SE9801139A SE513814C2 (sv)	1998-03-31	1998-03-31	Anordning för behandling av sjukdomar med elektriska fält
CA002325476A CA2325476A1 (en)	1998-03-31	1999-03-30	An apparatus for controlling the generation of electric fields
AT99918408T ATE309839T1 (de)	1998-03-31	1999-03-30	Gerät zur steuerung der generierung elektrischer felder
PCT/SE1999/000511 WO1999052589A1 (en)	1998-03-31	1999-03-30	An apparatus for controlling the generation of electric fields
EP99918408A EP1067985B1 (de)	1998-03-31	1999-03-30	Gerät zur steuerung der generierung elektrischer felder
JP2000543197A JP2002511320A (ja)	1998-03-31	1999-03-30	電界の発生を制御する装置
DE69928383T DE69928383T2 (de)	1998-03-31	1999-03-30	Gerät zur steuerung der generierung elektrischer felder
AU36338/99A AU741329B2 (en)	1998-03-31	1999-03-30	An apparatus for controlling the generation of electric fields
US11/204,258 US20060015147A1 (en)	1998-03-31	2005-08-15	Apparatus for controlling the generation of electric fields
US11/656,549 US20070118069A1 (en)	1998-03-31	2007-01-22	Apparatus for controlling the generation of electric fields
US13/168,350 US20120029508A1 (en)	1998-03-31	2011-06-24	Apparatus for controlling the generation of electric fields

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9801139A SE513814C2 (sv)	1998-03-31	1998-03-31	Anordning för behandling av sjukdomar med elektriska fält

Publications (3)

Publication Number	Publication Date
SE9801139D0 SE9801139D0 (sv)	1998-03-31
SE9801139L SE9801139L (sv)	1999-10-01
SE513814C2 true SE513814C2 (sv)	2000-11-06

Family

ID=20410817

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE9801139A SE513814C2 (sv)	1998-03-31	1998-03-31	Anordning för behandling av sjukdomar med elektriska fält

Country Status (9)

Country	Link
US (3)	US20060015147A1 (de)
EP (1)	EP1067985B1 (de)
JP (1)	JP2002511320A (de)
AT (1)	ATE309839T1 (de)
AU (1)	AU741329B2 (de)
CA (1)	CA2325476A1 (de)
DE (1)	DE69928383T2 (de)
SE (1)	SE513814C2 (de)
WO (1)	WO1999052589A1 (de)

Families Citing this family (101)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU733053C (en)	1998-02-24	2001-11-29	Boston Scientific Limited	High flow rate dialysis catheters and related methods
US6300108B1 (en) *	1999-07-21	2001-10-09	The Regents Of The University Of California	Controlled electroporation and mass transfer across cell membranes
EP1237620B1 (de) *	1999-12-15	2004-11-24	University of South Florida	Vorrichtung zur elektroporation
CA2400074A1 (en) *	2000-02-18	2001-08-23	William I. Higuchi	Methods for extracting substances using alternating current
IT1320520B1 (it) *	2000-04-21	2003-12-10	Igea Srl	Dispositivo e metodo di elettro-porazione in cui la misura delleproprieta' elettriche dei campioni svolta dopo l'emissione degli
US6795728B2 (en)	2001-08-17	2004-09-21	Minnesota Medical Physics, Llc	Apparatus and method for reducing subcutaneous fat deposits by electroporation
US6892099B2 (en) *	2001-02-08	2005-05-10	Minnesota Medical Physics, Llc	Apparatus and method for reducing subcutaneous fat deposits, virtual face lift and body sculpturing by electroporation
US8251986B2 (en)	2000-08-17	2012-08-28	Angiodynamics, Inc.	Method of destroying tissue cells by eletroporation
US6697670B2 (en) *	2001-08-17	2004-02-24	Minnesota Medical Physics, Llc	Apparatus and method for reducing subcutaneous fat deposits by electroporation with improved comfort of patients
US7137975B2 (en)	2001-02-13	2006-11-21	Aciont, Inc.	Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent
ITTO20010534A1 (it) *	2001-06-04	2002-12-04	Igea Srl	Dispositivo e metodo per elettroporazione che riduce la contrazione muscolare e la sensazione di dolore.
US6994706B2 (en)	2001-08-13	2006-02-07	Minnesota Medical Physics, Llc	Apparatus and method for treatment of benign prostatic hyperplasia
US7130697B2 (en) *	2002-08-13	2006-10-31	Minnesota Medical Physics Llc	Apparatus and method for the treatment of benign prostatic hyperplasia
USRE42016E1 (en)	2001-08-13	2010-12-28	Angiodynamics, Inc.	Apparatus and method for the treatment of benign prostatic hyperplasia
EP1696812B1 (de) *	2003-12-24	2015-07-22	The Regents of The University of California	Gewebeablation mit irreversibler elektroporation
US8298222B2 (en)	2003-12-24	2012-10-30	The Regents Of The University Of California	Electroporation to deliver chemotherapeutics and enhance tumor regression
JP4443278B2 (ja) *	2004-03-26	2010-03-31	テルモ株式会社	拡張体付カテーテル
FR2873385B1 (fr) *	2004-07-23	2006-10-27	Centre Nat Rech Scient Cnrse	Surveillance et controle d'une electroporation
US20060264752A1 (en) *	2005-04-27	2006-11-23	The Regents Of The University Of California	Electroporation controlled with real time imaging
US8114070B2 (en) *	2005-06-24	2012-02-14	Angiodynamics, Inc.	Methods and systems for treating BPH using electroporation
US20060293731A1 (en) *	2005-06-24	2006-12-28	Boris Rubinsky	Methods and systems for treating tumors using electroporation
US20060293730A1 (en) *	2005-06-24	2006-12-28	Boris Rubinsky	Methods and systems for treating restenosis sites using electroporation
US20060293725A1 (en) *	2005-06-24	2006-12-28	Boris Rubinsky	Methods and systems for treating fatty tissue sites using electroporation
US8214221B2 (en) *	2005-06-30	2012-07-03	Lg Electronics Inc.	Method and apparatus for decoding an audio signal and identifying information included in the audio signal
US20070078502A1 (en) *	2005-10-05	2007-04-05	Thermage, Inc.	Method and apparatus for estimating a local impedance factor
US8702691B2 (en) *	2005-10-19	2014-04-22	Thermage, Inc.	Treatment apparatus and methods for delivering energy at multiple selectable depths in tissue
US20070156135A1 (en) *	2006-01-03	2007-07-05	Boris Rubinsky	System and methods for treating atrial fibrillation using electroporation
US7674249B2 (en) *	2006-10-16	2010-03-09	The Regents Of The University Of California	Gels with predetermined conductivity used in electroporation of tissue
US20080132884A1 (en) *	2006-12-01	2008-06-05	Boris Rubinsky	Systems for treating tissue sites using electroporation
US8216218B2 (en) *	2007-07-10	2012-07-10	Thermage, Inc.	Treatment apparatus and methods for delivering high frequency energy across large tissue areas
SE532140C2 (sv) *	2007-09-28	2009-11-03	Clinical Laserthermia Systems	Anordning för positionering av implanterbara ledningar
DE102008008614A1 (de)	2008-02-12	2009-08-13	Leibniz-Institut für Plasmaforschung und Technologie e.V.	Plama-Gerät zur selektiven Behandlung elektroporierter Zellen
US20100004623A1 (en) *	2008-03-27	2010-01-07	Angiodynamics, Inc.	Method for Treatment of Complications Associated with Arteriovenous Grafts and Fistulas Using Electroporation
US20090248012A1 (en) *	2008-03-27	2009-10-01	The Regents Of The University Of California	Irreversible electroporation device and method for attenuating neointimal
US10272178B2 (en)	2008-04-29	2019-04-30	Virginia Tech Intellectual Properties Inc.	Methods for blood-brain barrier disruption using electrical energy
US8992517B2 (en) *	2008-04-29	2015-03-31	Virginia Tech Intellectual Properties Inc.	Irreversible electroporation to treat aberrant cell masses
US9867652B2 (en)	2008-04-29	2018-01-16	Virginia Tech Intellectual Properties, Inc.	Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
US9198733B2 (en)	2008-04-29	2015-12-01	Virginia Tech Intellectual Properties, Inc.	Treatment planning for electroporation-based therapies
US9598691B2 (en)	2008-04-29	2017-03-21	Virginia Tech Intellectual Properties, Inc.	Irreversible electroporation to create tissue scaffolds
US10245098B2 (en)	2008-04-29	2019-04-02	Virginia Tech Intellectual Properties, Inc.	Acute blood-brain barrier disruption using electrical energy based therapy
US10702326B2 (en)	2011-07-15	2020-07-07	Virginia Tech Intellectual Properties, Inc.	Device and method for electroporation based treatment of stenosis of a tubular body part
US10238447B2 (en)	2008-04-29	2019-03-26	Virginia Tech Intellectual Properties, Inc.	System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
US10117707B2 (en)	2008-04-29	2018-11-06	Virginia Tech Intellectual Properties, Inc.	System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US11254926B2 (en)	2008-04-29	2022-02-22	Virginia Tech Intellectual Properties, Inc.	Devices and methods for high frequency electroporation
US9283051B2 (en)	2008-04-29	2016-03-15	Virginia Tech Intellectual Properties, Inc.	System and method for estimating a treatment volume for administering electrical-energy based therapies
US11272979B2 (en)	2008-04-29	2022-03-15	Virginia Tech Intellectual Properties, Inc.	System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
WO2009137800A2 (en)	2008-05-09	2009-11-12	Angiodynamics, Inc.	Electroporation device and method
WO2009155526A2 (en) *	2008-06-20	2009-12-23	Angiodynamics, Inc.	Device and method for the ablation of fibrin sheath formation on a venous catheter
US9681909B2 (en) *	2008-06-23	2017-06-20	Angiodynamics, Inc.	Treatment devices and methods
US20100152725A1 (en) *	2008-12-12	2010-06-17	Angiodynamics, Inc.	Method and system for tissue treatment utilizing irreversible electroporation and thermal track coagulation
US8753335B2 (en) *	2009-01-23	2014-06-17	Angiodynamics, Inc.	Therapeutic energy delivery device with rotational mechanism
WO2010093692A2 (en) *	2009-02-10	2010-08-19	Hobbs Eamonn P	Irreversible electroporation and tissue regeneration
US8632534B2 (en)	2009-04-03	2014-01-21	Angiodynamics, Inc.	Irreversible electroporation (IRE) for congestive obstructive pulmonary disease (COPD)
US11382681B2 (en)	2009-04-09	2022-07-12	Virginia Tech Intellectual Properties, Inc.	Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
US11638603B2 (en)	2009-04-09	2023-05-02	Virginia Tech Intellectual Properties, Inc.	Selective modulation of intracellular effects of cells using pulsed electric fields
WO2010118387A1 (en) *	2009-04-09	2010-10-14	Virginia Tech Intellectual Properties, Inc.	Integration of very short electric pulses for minimally to noninvasive electroporation
USD630321S1 (en)	2009-05-08	2011-01-04	Angio Dynamics, Inc.	Probe handle
WO2010138919A2 (en)	2009-05-28	2010-12-02	Angiodynamics, Inc.	System and method for synchronizing energy delivery to the cardiac rhythm
US9895189B2 (en)	2009-06-19	2018-02-20	Angiodynamics, Inc.	Methods of sterilization and treating infection using irreversible electroporation
DE102009028462A1 (de)	2009-08-11	2011-03-24	Leibniz-Institut für Plasmaforschung und Technologie e.V.	Vorrichtung und Verfahren zur Behandlung von lebenden Zellen mittels eines Plasmas
US20110118732A1 (en)	2009-11-19	2011-05-19	The Regents Of The University Of California	Controlled irreversible electroporation
DE102010011643B4 (de) *	2010-03-16	2024-05-29	Christian Buske	Vorrichtung und Verfahren zur Plasmabehandlung von lebendem Gewebe
KR101145770B1 (ko) *	2010-07-15	2012-05-16	한국전자통신연구원	고전력 펄스 신호 복사 시스템
EP2627274B1 (de)	2010-10-13	2022-12-14	AngioDynamics, Inc.	System zur elektrischen ableitung des gewebes eines patienten
US8987720B2 (en)	2010-12-13	2015-03-24	Konica Minolta, Inc.	Transparent surface electrode, organic electronic element, and method for manufacturing transparent surface electrode
WO2012088149A2 (en)	2010-12-20	2012-06-28	Virginia Tech Intellectual Properties, Inc.	High-frequency electroporation for cancer therapy
US9078665B2 (en)	2011-09-28	2015-07-14	Angiodynamics, Inc.	Multiple treatment zone ablation probe
US8865340B2 (en)	2011-10-20	2014-10-21	Front Edge Technology Inc.	Thin film battery packaging formed by localized heating
GB2496449A (en) *	2011-11-14	2013-05-15	Louise Mohn	Electrical stimulation apparatus for the body
US9887429B2 (en)	2011-12-21	2018-02-06	Front Edge Technology Inc.	Laminated lithium battery
US8864954B2 (en)	2011-12-23	2014-10-21	Front Edge Technology Inc.	Sputtering lithium-containing material with multiple targets
US9414881B2 (en)	2012-02-08	2016-08-16	Angiodynamics, Inc.	System and method for increasing a target zone for electrical ablation
US9077000B2 (en)	2012-03-29	2015-07-07	Front Edge Technology, Inc.	Thin film battery and localized heat treatment
US9257695B2 (en)	2012-03-29	2016-02-09	Front Edge Technology, Inc.	Localized heat treatment of battery component films
US9159964B2 (en)	2012-09-25	2015-10-13	Front Edge Technology, Inc.	Solid state battery having mismatched battery cells
US9356320B2 (en)	2012-10-15	2016-05-31	Front Edge Technology Inc.	Lithium battery having low leakage anode
US10166321B2 (en)	2014-01-09	2019-01-01	Angiodynamics, Inc.	High-flow port and infusion needle systems
AU2015259303B2 (en)	2014-05-12	2021-10-28	Arena, Christopher B.	Selective modulation of intracellular effects of cells using pulsed electric fields
US12114911B2 (en)	2014-08-28	2024-10-15	Angiodynamics, Inc.	System and method for ablating a tissue site by electroporation with real-time pulse monitoring
US20170231548A1 (en) *	2014-10-29	2017-08-17	Indiana University Research And Technology Corporation	System and method for bladder transducer placement
US10694972B2 (en)	2014-12-15	2020-06-30	Virginia Tech Intellectual Properties, Inc.	Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
US10008739B2 (en)	2015-02-23	2018-06-26	Front Edge Technology, Inc.	Solid-state lithium battery with electrolyte
US10905492B2 (en)	2016-11-17	2021-02-02	Angiodynamics, Inc.	Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
JP6733513B2 (ja) *	2016-11-18	2020-08-05	オムロンヘルスケア株式会社	電気治療器、および治療システム
EP3421080B1 (de)	2017-06-28	2021-05-05	Fundación Tecnalia Research & Innovation	Vorrichtung zur kontrollierten und überwachten transdermalen wirkstofffreisetzung und verwendung davon
SE541651C2 (en)	2017-07-28	2019-11-19	Scandinavian Chemotech Ab	An electrode device and a needle electrode for use in delivery of electrical pulses to a desired tissue of a mammal
ES2883421T3 (es)	2017-07-28	2021-12-07	Scandinavian Chemotech Ab	Un dispositivo, por ejemplo, un dispositivo de control de dolor mejorado electrodinámico (DEEPC), para el suministro de pulsos eléctricos a una parte del cuerpo deseada de un mamífero
SE542514C2 (en)	2017-07-28	2020-05-26	Scandinavian Chemotech Ab	A pulse generating device for delivery of electrical pulses to a desired tissue of a mammal
US10850095B2 (en)	2017-08-08	2020-12-01	Pulse Biosciences, Inc.	Treatment of tissue by the application of energy
US11590345B2 (en)	2017-08-08	2023-02-28	Pulse Biosciences, Inc.	Treatment of tissue by the application of energy
US10857347B2 (en)	2017-09-19	2020-12-08	Pulse Biosciences, Inc.	Treatment instrument and high-voltage connectors for robotic surgical system
US11607537B2 (en)	2017-12-05	2023-03-21	Virginia Tech Intellectual Properties, Inc.	Method for treating neurological disorders, including tumors, with electroporation
US11925405B2 (en)	2018-03-13	2024-03-12	Virginia Tech Intellectual Properties, Inc.	Treatment planning system for immunotherapy enhancement via non-thermal ablation
US12390262B2 (en)	2018-03-13	2025-08-19	Virginia Tech Intellectual Properties, Inc.	Treatment planning system for immunotherapy enhancement via non-thermal ablation
US11311329B2 (en)	2018-03-13	2022-04-26	Virginia Tech Intellectual Properties, Inc.	Treatment planning for immunotherapy based treatments using non-thermal ablation techniques
DE102018129541A1 (de) *	2018-11-23	2020-05-28	Pajunk GmbH Medizintechnologie	Multipolare Kanüle
US11571569B2 (en)	2019-02-15	2023-02-07	Pulse Biosciences, Inc.	High-voltage catheters for sub-microsecond pulsing
US11950835B2 (en)	2019-06-28	2024-04-09	Virginia Tech Intellectual Properties, Inc.	Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy
US12214189B2 (en)	2019-07-24	2025-02-04	Virginia Tech Intellectual Properties, Inc.	Fourier analysis spectroscopy for monitoring tissue impedance changes and treatment outcome during electroporation-based-therapies
US12485279B2 (en)	2020-11-25	2025-12-02	Virginia Tech Intellectual Properties, Inc.	Methods for modulating temporal infrastructure of pulsed electric fields
WO2023161796A1 (en) *	2022-02-23	2023-08-31	Cochlear Limited	Adaptive electroporation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4141359A (en) *	1976-08-16	1979-02-27	University Of Utah	Epidermal iontophoresis device
DE68925030T2 (de) *	1988-01-21	1996-07-25	Massachusetts Inst Technology	Molekültransport durch gewebe mit der verwendung von elektroporation.
US5300068A (en) *	1992-04-21	1994-04-05	St. Jude Medical, Inc.	Electrosurgical apparatus
SE469465B (sv) *	1992-05-08	1993-07-12	Jens Schouenborg	Medicinsk anordning foer lindring av smaerttillstaand innefattande en elektrodplatta
US5688233A (en) *	1992-08-17	1997-11-18	Genetronics, Inc.	Electronincorporation enhanced transdermal delivery of molecules
US5370645A (en) *	1993-04-19	1994-12-06	Valleylab Inc.	Electrosurgical processor and method of use
US5817093A (en) *	1993-07-22	1998-10-06	Ethicon Endo-Surgery, Inc.	Impedance feedback monitor with query electrode for electrosurgical instrument
US5498227A (en) *	1993-09-15	1996-03-12	Mawad; Michel E.	Retrievable, shielded radiotherapy implant
US5928229A (en) *	1993-11-08	1999-07-27	Rita Medical Systems, Inc.	Tumor ablation apparatus
US5527357A (en) *	1994-06-24	1996-06-18	Springer, Jr.; George E.	Apparatus for toning facial tissue
US5630426A (en) *	1995-03-03	1997-05-20	Neovision Corporation	Apparatus and method for characterization and treatment of tumors
US6167301A (en) *	1995-08-29	2000-12-26	Flower; Ronald J.	Iontophoretic drug delivery device having high-efficiency DC-to-DC energy conversion circuit
EP0847775B1 (de) *	1995-08-31	2004-10-27	Hisamitsu Pharmaceutical Co. Inc.	Iontophoretische vorrichtung und entsprechendes verfahren zur steuerung des stromes
US5716392A (en) *	1996-01-05	1998-02-10	Medtronic, Inc.	Minimally invasive medical electrical lead
EP1003847A4 (de) *	1997-09-04	2005-04-06	Science Res Lab Inc	Zelltrennung mittels elektrischer felder
US6208893B1 (en) *	1998-01-27	2001-03-27	Genetronics, Inc.	Electroporation apparatus with connective electrode template

1998
- 1998-03-31 SE SE9801139A patent/SE513814C2/sv not_active IP Right Cessation
1999
- 1999-03-30 DE DE69928383T patent/DE69928383T2/de not_active Expired - Lifetime
- 1999-03-30 CA CA002325476A patent/CA2325476A1/en not_active Abandoned
- 1999-03-30 JP JP2000543197A patent/JP2002511320A/ja active Pending
- 1999-03-30 EP EP99918408A patent/EP1067985B1/de not_active Expired - Lifetime
- 1999-03-30 AU AU36338/99A patent/AU741329B2/en not_active Ceased
- 1999-03-30 AT AT99918408T patent/ATE309839T1/de not_active IP Right Cessation
- 1999-03-30 WO PCT/SE1999/000511 patent/WO1999052589A1/en not_active Ceased
2005
- 2005-08-15 US US11/204,258 patent/US20060015147A1/en not_active Abandoned
2007
- 2007-01-22 US US11/656,549 patent/US20070118069A1/en not_active Abandoned
2011
- 2011-06-24 US US13/168,350 patent/US20120029508A1/en not_active Abandoned

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Publication number	Publication date
CA2325476A1 (en)	1999-10-21
US20120029508A1 (en)	2012-02-02
DE69928383T2 (de)	2006-08-03
SE9801139D0 (sv)	1998-03-31
AU3633899A (en)	1999-11-01
EP1067985A1 (de)	2001-01-17
SE9801139L (sv)	1999-10-01
DE69928383D1 (de)	2005-12-22
WO1999052589A1 (en)	1999-10-21
AU741329B2 (en)	2001-11-29
JP2002511320A (ja)	2002-04-16
US20070118069A1 (en)	2007-05-24
EP1067985B1 (de)	2005-11-16
ATE309839T1 (de)	2005-12-15
US20060015147A1 (en)	2006-01-19

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2014-12-02	NUG	Patent has lapsed

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