SE524334C2 - Värmegenererande biokompatibla keramiska material och förfarande för dess framställning - Google Patents

Värmegenererande biokompatibla keramiska material och förfarande för dess framställning

Info

Publication number: SE524334C2
Authority: SE; Sweden
Prior art keywords: ceramic composition; composition according; biocompatible ceramic; volume; curing
Prior art date: 2002-09-30

Application number

SE0202895A

Other languages

English (en)

Swedish (sv)

Other versions

SE0202895D0 (sv

SE0202895L (sv

Inventor

Niklas Axen

Tobias Persson

Dan Markusson

Leif Hermansson

Original Assignee

Cerbio Tech Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-09-30

Filing date

2002-09-30

Publication date

2004-07-27

2002-09-30 Application filed by Cerbio Tech Ab filed Critical Cerbio Tech Ab

2002-09-30 Priority to SE0202895A priority Critical patent/SE524334C2/sv

2002-09-30 Publication of SE0202895D0 publication Critical patent/SE0202895D0/xx

2003-09-25 Priority to RU2005113277/15A priority patent/RU2323014C2/ru

2003-09-25 Priority to AU2003263719A priority patent/AU2003263719A1/en

2003-09-25 Priority to JP2004539711A priority patent/JP2006504702A/ja

2003-09-25 Priority to DE60325622T priority patent/DE60325622D1/de

2003-09-25 Priority to BR0313954-9A priority patent/BR0313954A/pt

2003-09-25 Priority to KR1020057005478A priority patent/KR101100449B1/ko

2003-09-25 Priority to CA002499259A priority patent/CA2499259A1/en

2003-09-25 Priority to PCT/SE2003/001489 priority patent/WO2004028577A1/en

2003-09-25 Priority to CNB038233843A priority patent/CN100384487C/zh

2003-09-25 Priority to AT03798636T priority patent/ATE419018T1/de

2003-09-25 Priority to EP03798636A priority patent/EP1551468B1/de

2003-09-30 Priority to US10/673,250 priority patent/US7244301B2/en

2004-03-31 Publication of SE0202895L publication Critical patent/SE0202895L/xx

2004-07-27 Publication of SE524334C2 publication Critical patent/SE524334C2/sv

2007-06-13 Priority to US11/762,293 priority patent/US20070233213A1/en

2007-06-13 Priority to US11/762,370 priority patent/US20070232704A1/en

Links

238000000034 method Methods 0.000 title claims description 23
230000008569 process Effects 0.000 title claims description 14
238000002360 preparation method Methods 0.000 title claims 2
229910010293 ceramic material Inorganic materials 0.000 title description 8
239000000203 mixture Substances 0.000 claims abstract description 88
239000000919 ceramic Substances 0.000 claims abstract description 54
XFWJKVMFIVXPKK-UHFFFAOYSA-N calcium;oxido(oxo)alumane Chemical compound [Ca+2].[O-][Al]=O.[O-][Al]=O XFWJKVMFIVXPKK-UHFFFAOYSA-N 0.000 claims abstract description 35
239000000843 powder Substances 0.000 claims description 39
239000000463 material Substances 0.000 claims description 32
KWGKDLIKAYFUFQ-UHFFFAOYSA-M lithium chloride Chemical compound [Li+].[Cl-] KWGKDLIKAYFUFQ-UHFFFAOYSA-M 0.000 claims description 30
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 29
229910001868 water Inorganic materials 0.000 claims description 26
239000000654 additive Substances 0.000 claims description 18
KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 15
239000003795 chemical substances by application Substances 0.000 claims description 15
239000011575 calcium Substances 0.000 claims description 13
239000007788 liquid Substances 0.000 claims description 13
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 12
229910052791 calcium Inorganic materials 0.000 claims description 11
239000004615 ingredient Substances 0.000 claims description 10
WMFOQBRAJBCJND-UHFFFAOYSA-M Lithium hydroxide Chemical compound [Li+].[OH-] WMFOQBRAJBCJND-UHFFFAOYSA-M 0.000 claims description 9
239000002002 slurry Substances 0.000 claims description 8
239000000378 calcium silicate Substances 0.000 claims description 7
229910052918 calcium silicate Inorganic materials 0.000 claims description 7
OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 claims description 7
238000004519 manufacturing process Methods 0.000 claims description 7
230000000399 orthopedic effect Effects 0.000 claims description 7
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 6
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 6
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 6
OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 6
239000003638 chemical reducing agent Substances 0.000 claims description 6
239000000945 filler Substances 0.000 claims description 6
IIPYXGDZVMZOAP-UHFFFAOYSA-N lithium nitrate Chemical compound [Li+].[O-][N+]([O-])=O IIPYXGDZVMZOAP-UHFFFAOYSA-N 0.000 claims description 6
VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 5
239000000560 biocompatible material Substances 0.000 claims description 5
239000007943 implant Substances 0.000 claims description 5
239000002245 particle Substances 0.000 claims description 5
239000002994 raw material Substances 0.000 claims description 5
235000000346 sugar Nutrition 0.000 claims description 5
235000011132 calcium sulphate Nutrition 0.000 claims description 4
239000000356 contaminant Substances 0.000 claims description 4
238000011049 filling Methods 0.000 claims description 4
BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 claims description 4
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 3
PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 3
229920002125 Sokalan® Polymers 0.000 claims description 3
229920002472 Starch Polymers 0.000 claims description 3
239000002253 acid Substances 0.000 claims description 3
150000007513 acids Chemical class 0.000 claims description 3
239000001506 calcium phosphate Substances 0.000 claims description 3
235000011010 calcium phosphates Nutrition 0.000 claims description 3
239000001175 calcium sulphate Substances 0.000 claims description 3
239000001913 cellulose Substances 0.000 claims description 3
229920002678 cellulose Polymers 0.000 claims description 3
235000010980 cellulose Nutrition 0.000 claims description 3
239000004053 dental implant Substances 0.000 claims description 3
150000004676 glycans Chemical class 0.000 claims description 3
235000011187 glycerol Nutrition 0.000 claims description 3
XGZVUEUWXADBQD-UHFFFAOYSA-L lithium carbonate Chemical compound [Li+].[Li+].[O-]C([O-])=O XGZVUEUWXADBQD-UHFFFAOYSA-L 0.000 claims description 3
229910052808 lithium carbonate Inorganic materials 0.000 claims description 3
INHCSSUBVCNVSK-UHFFFAOYSA-L lithium sulfate Inorganic materials [Li+].[Li+].[O-]S([O-])(=O)=O INHCSSUBVCNVSK-UHFFFAOYSA-L 0.000 claims description 3
229910052751 metal Inorganic materials 0.000 claims description 3
239000002184 metal Substances 0.000 claims description 3
150000002739 metals Chemical class 0.000 claims description 3
229920001282 polysaccharide Polymers 0.000 claims description 3
239000005017 polysaccharide Substances 0.000 claims description 3
229910000029 sodium carbonate Inorganic materials 0.000 claims description 3
239000008107 starch Substances 0.000 claims description 3
235000019698 starch Nutrition 0.000 claims description 3
RBTVSNLYYIMMKS-UHFFFAOYSA-N tert-butyl 3-aminoazetidine-1-carboxylate;hydrochloride Chemical compound Cl.CC(C)(C)OC(=O)N1CC(N)C1 RBTVSNLYYIMMKS-UHFFFAOYSA-N 0.000 claims description 3
239000002562 thickening agent Substances 0.000 claims description 3
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 3
BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 2
229910052586 apatite Inorganic materials 0.000 claims description 2
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 2
229910052788 barium Inorganic materials 0.000 claims description 2
229910000019 calcium carbonate Inorganic materials 0.000 claims description 2
229910000389 calcium phosphate Inorganic materials 0.000 claims description 2
AOWKSNWVBZGMTJ-UHFFFAOYSA-N calcium titanate Chemical compound [Ca+2].[O-][Ti]([O-])=O AOWKSNWVBZGMTJ-UHFFFAOYSA-N 0.000 claims description 2
150000001875 compounds Chemical class 0.000 claims description 2
239000003937 drug carrier Substances 0.000 claims description 2
238000012377 drug delivery Methods 0.000 claims description 2
229910052735 hafnium Inorganic materials 0.000 claims description 2
229910052588 hydroxylapatite Inorganic materials 0.000 claims description 2
229910052749 magnesium Inorganic materials 0.000 claims description 2
229910052760 oxygen Inorganic materials 0.000 claims description 2
239000001301 oxygen Substances 0.000 claims description 2
VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 claims description 2
XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 2
229910000027 potassium carbonate Inorganic materials 0.000 claims description 2
229910052938 sodium sulfate Inorganic materials 0.000 claims description 2
235000011152 sodium sulphate Nutrition 0.000 claims description 2
229910052712 strontium Inorganic materials 0.000 claims description 2
229910052719 titanium Inorganic materials 0.000 claims description 2
229910052726 zirconium Inorganic materials 0.000 claims description 2
229910052587 fluorapatite Inorganic materials 0.000 claims 1
229910021485 fumed silica Inorganic materials 0.000 claims 1
238000011282 treatment Methods 0.000 abstract description 20
206010028980 Neoplasm Diseases 0.000 abstract description 12
230000001225 therapeutic effect Effects 0.000 abstract description 9
208000002193 Pain Diseases 0.000 abstract description 8
238000011065 in-situ storage Methods 0.000 abstract description 6
230000002792 vascular Effects 0.000 abstract description 6
239000003814 drug Substances 0.000 abstract description 4
229940079593 drug Drugs 0.000 abstract description 4
238000001727 in vivo Methods 0.000 abstract description 4
230000004913 activation Effects 0.000 abstract description 3
230000008821 health effect Effects 0.000 abstract description 3
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000011343 solid material Substances 0.000 abstract 1
238000006703 hydration reaction Methods 0.000 description 32
230000036571 hydration Effects 0.000 description 30
239000004568 cement Substances 0.000 description 18
239000002639 bone cement Substances 0.000 description 17
229920003229 poly(methyl methacrylate) Polymers 0.000 description 13
239000004926 polymethyl methacrylate Substances 0.000 description 13
-1 calcium aluminates Chemical class 0.000 description 9
238000000227 grinding Methods 0.000 description 9
239000000243 solution Substances 0.000 description 9
210000000988 bone and bone Anatomy 0.000 description 8
238000006243 chemical reaction Methods 0.000 description 8
230000000694 effects Effects 0.000 description 8
150000004677 hydrates Chemical class 0.000 description 7
235000012241 calcium silicate Nutrition 0.000 description 6
239000011396 hydraulic cement Substances 0.000 description 6
230000020169 heat generation Effects 0.000 description 5
229920003023 plastic Polymers 0.000 description 4
239000004033 plastic Substances 0.000 description 4
239000007787 solid Substances 0.000 description 4
150000004645 aluminates Chemical class 0.000 description 3
239000007864 aqueous solution Substances 0.000 description 3
201000011510 cancer Diseases 0.000 description 3
230000000887 hydrating effect Effects 0.000 description 3
238000002347 injection Methods 0.000 description 3
239000007924 injection Substances 0.000 description 3
230000001009 osteoporotic effect Effects 0.000 description 3
239000007858 starting material Substances 0.000 description 3
239000000126 substance Substances 0.000 description 3
238000002560 therapeutic procedure Methods 0.000 description 3
210000001519 tissue Anatomy 0.000 description 3
206010017076 Fracture Diseases 0.000 description 2
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
229910052782 aluminium Inorganic materials 0.000 description 2
230000008901 benefit Effects 0.000 description 2
235000010216 calcium carbonate Nutrition 0.000 description 2
AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 2
239000000920 calcium hydroxide Substances 0.000 description 2
229910001861 calcium hydroxide Inorganic materials 0.000 description 2
238000002659 cell therapy Methods 0.000 description 2
230000006378 damage Effects 0.000 description 2
239000008367 deionised water Substances 0.000 description 2
229910021641 deionized water Inorganic materials 0.000 description 2
230000002349 favourable effect Effects 0.000 description 2
239000012530 fluid Substances 0.000 description 2
239000003112 inhibitor Substances 0.000 description 2
229940071264 lithium citrate Drugs 0.000 description 2
WJSIUCDMWSDDCE-UHFFFAOYSA-K lithium citrate (anhydrous) Chemical compound [Li+].[Li+].[Li+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O WJSIUCDMWSDDCE-UHFFFAOYSA-K 0.000 description 2
230000007246 mechanism Effects 0.000 description 2
239000000178 monomer Substances 0.000 description 2
230000017074 necrotic cell death Effects 0.000 description 2
210000000056 organ Anatomy 0.000 description 2
238000001556 precipitation Methods 0.000 description 2
238000001959 radiotherapy Methods 0.000 description 2
230000009467 reduction Effects 0.000 description 2
150000003839 salts Chemical class 0.000 description 2
239000002904 solvent Substances 0.000 description 2
238000001356 surgical procedure Methods 0.000 description 2
238000012546 transfer Methods 0.000 description 2
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
206010027476 Metastases Diseases 0.000 description 1
241000906034 Orthops Species 0.000 description 1
241000283903 Ovis aries Species 0.000 description 1
206010035226 Plasma cell myeloma Diseases 0.000 description 1
239000011398 Portland cement Substances 0.000 description 1
229910052581 Si3N4 Inorganic materials 0.000 description 1
206010072005 Spinal pain Diseases 0.000 description 1
208000027418 Wounds and injury Diseases 0.000 description 1
PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
230000009286 beneficial effect Effects 0.000 description 1
239000011230 binding agent Substances 0.000 description 1
239000012620 biological material Substances 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
239000008280 blood Substances 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
210000004204 blood vessel Anatomy 0.000 description 1
210000001124 body fluid Anatomy 0.000 description 1
239000010839 body fluid Substances 0.000 description 1
230000036760 body temperature Effects 0.000 description 1
229910052796 boron Inorganic materials 0.000 description 1
150000004649 carbonic acid derivatives Chemical class 0.000 description 1
239000013065 commercial product Substances 0.000 description 1
229910052593 corundum Inorganic materials 0.000 description 1
208000031513 cyst Diseases 0.000 description 1
230000003111 delayed effect Effects 0.000 description 1
239000005548 dental material Substances 0.000 description 1
230000001419 dependent effect Effects 0.000 description 1
238000011161 development Methods 0.000 description 1
238000004090 dissolution Methods 0.000 description 1
238000009472 formulation Methods 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
229930195733 hydrocarbon Natural products 0.000 description 1
150000002430 hydrocarbons Chemical class 0.000 description 1
208000014674 injury Diseases 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
210000003127 knee Anatomy 0.000 description 1
230000003211 malignant effect Effects 0.000 description 1
238000002156 mixing Methods 0.000 description 1
201000000050 myeloid neoplasm Diseases 0.000 description 1
210000005036 nerve Anatomy 0.000 description 1
231100000252 nontoxic Toxicity 0.000 description 1
230000003000 nontoxic effect Effects 0.000 description 1
235000015097 nutrients Nutrition 0.000 description 1
229910052574 oxide ceramic Inorganic materials 0.000 description 1
239000011224 oxide ceramic Substances 0.000 description 1
238000006213 oxygenation reaction Methods 0.000 description 1
238000010422 painting Methods 0.000 description 1
239000011236 particulate material Substances 0.000 description 1
239000004014 plasticizer Substances 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
238000006116 polymerization reaction Methods 0.000 description 1
239000002244 precipitate Substances 0.000 description 1
239000000047 product Substances 0.000 description 1
230000005855 radiation Effects 0.000 description 1
238000011160 research Methods 0.000 description 1
238000007873 sieving Methods 0.000 description 1
150000004760 silicates Chemical class 0.000 description 1
239000000377 silicon dioxide Substances 0.000 description 1
HQVNEWCFYHHQES-UHFFFAOYSA-N silicon nitride Chemical compound N12[Si]34N5[Si]62N3[Si]51N64 HQVNEWCFYHHQES-UHFFFAOYSA-N 0.000 description 1
238000007711 solidification Methods 0.000 description 1
230000008023 solidification Effects 0.000 description 1
230000006641 stabilisation Effects 0.000 description 1
238000011105 stabilization Methods 0.000 description 1
238000012144 step-by-step procedure Methods 0.000 description 1
150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
239000008030 superplasticizer Substances 0.000 description 1
231100000331 toxic Toxicity 0.000 description 1
230000002588 toxic effect Effects 0.000 description 1
210000001585 trabecular meshwork Anatomy 0.000 description 1
230000003313 weakening effect Effects 0.000 description 1
229910001845 yogo sapphire Inorganic materials 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/10—Ceramics or glasses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Oral & Maxillofacial Surgery (AREA)
Dermatology (AREA)
Transplantation (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Inorganic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Ceramic Engineering (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Neurology (AREA)
Cardiology (AREA)
Materials For Medical Uses (AREA)
Dental Preparations (AREA)
Compositions Of Oxide Ceramics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Prostheses (AREA)
Medicinal Preparation (AREA)

SE0202895A 2002-09-30 2002-09-30 Värmegenererande biokompatibla keramiska material och förfarande för dess framställning SE524334C2 (sv)

Priority Applications (15)

Application Number	Priority Date	Filing Date	Title
SE0202895A SE524334C2 (sv)	2002-09-30	2002-09-30	Värmegenererande biokompatibla keramiska material och förfarande för dess framställning
EP03798636A EP1551468B1 (de)	2002-09-30	2003-09-25	Wärme erzeugende biokompatible keramikmaterialien
KR1020057005478A KR101100449B1 (ko)	2002-09-30	2003-09-25	열 발생 생체적합성 세라믹 물질
PCT/SE2003/001489 WO2004028577A1 (en)	2002-09-30	2003-09-25	Heat generating biocompatible ceramic materials
JP2004539711A JP2006504702A (ja)	2002-09-30	2003-09-25	発熱生体適合性セラミック材料
DE60325622T DE60325622D1 (de)	2002-09-30	2003-09-25	Wärme erzeugende biokompatible keramikmaterialien
BR0313954-9A BR0313954A (pt)	2002-09-30	2003-09-25	Composição de cerâmica biocompatìvel, dispositivo médico, método para fabricar uma composição de cerâmica biocompatìvel, implantes médico e ortopédico, material de enchimento dental ou implante dental, veìculo de droga para liberação de droga no corpo de um paciente, uso da composição de cerâmica biocompatìvel, método para gerar calor in vivo no corpo de um paciente para propósitos terapêuticos, e, método terapêutico
RU2005113277/15A RU2323014C2 (ru)	2002-09-30	2003-09-25	Тепловыделяющие биосовместимые керамические материалы
CA002499259A CA2499259A1 (en)	2002-09-30	2003-09-25	Heat generating biocompatible ceramic materials
AU2003263719A AU2003263719A1 (en)	2002-09-30	2003-09-25	Heat generating biocompatible ceramic materials
CNB038233843A CN100384487C (zh)	2002-09-30	2003-09-25	发热生物相容陶瓷材料
AT03798636T ATE419018T1 (de)	2002-09-30	2003-09-25	Wärme erzeugende biokompatible keramikmaterialien
US10/673,250 US7244301B2 (en)	2002-09-30	2003-09-30	Heat generating biocompatible ceramic materials
US11/762,293 US20070233213A1 (en)	2002-09-30	2007-06-13	Method of therapeutic treatment using a biocompatible ceramic composition
US11/762,370 US20070232704A1 (en)	2002-09-30	2007-06-13	Heat generating biocompatible ceramic materials for drug delivery

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE0202895A SE524334C2 (sv)	2002-09-30	2002-09-30	Värmegenererande biokompatibla keramiska material och förfarande för dess framställning

Publications (3)

Publication Number	Publication Date
SE0202895D0 SE0202895D0 (sv)	2002-09-30
SE0202895L SE0202895L (sv)	2004-03-31
SE524334C2 true SE524334C2 (sv)	2004-07-27

Family

ID=20289141

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE0202895A SE524334C2 (sv)	2002-09-30	2002-09-30	Värmegenererande biokompatibla keramiska material och förfarande för dess framställning

Country Status (13)

Country	Link
US (3)	US7244301B2 (de)
EP (1)	EP1551468B1 (de)
JP (1)	JP2006504702A (de)
KR (1)	KR101100449B1 (de)
CN (1)	CN100384487C (de)
AT (1)	ATE419018T1 (de)
AU (1)	AU2003263719A1 (de)
BR (1)	BR0313954A (de)
CA (1)	CA2499259A1 (de)
DE (1)	DE60325622D1 (de)
RU (1)	RU2323014C2 (de)
SE (1)	SE524334C2 (de)
WO (1)	WO2004028577A1 (de)

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2002
- 2002-09-30 SE SE0202895A patent/SE524334C2/sv unknown
2003
- 2003-09-25 EP EP03798636A patent/EP1551468B1/de not_active Expired - Lifetime
- 2003-09-25 CA CA002499259A patent/CA2499259A1/en not_active Abandoned
- 2003-09-25 AU AU2003263719A patent/AU2003263719A1/en not_active Abandoned
- 2003-09-25 AT AT03798636T patent/ATE419018T1/de not_active IP Right Cessation
- 2003-09-25 RU RU2005113277/15A patent/RU2323014C2/ru not_active IP Right Cessation
- 2003-09-25 DE DE60325622T patent/DE60325622D1/de not_active Expired - Lifetime
- 2003-09-25 WO PCT/SE2003/001489 patent/WO2004028577A1/en not_active Ceased
- 2003-09-25 JP JP2004539711A patent/JP2006504702A/ja active Pending
- 2003-09-25 CN CNB038233843A patent/CN100384487C/zh not_active Expired - Fee Related
- 2003-09-25 KR KR1020057005478A patent/KR101100449B1/ko not_active Expired - Fee Related
- 2003-09-25 BR BR0313954-9A patent/BR0313954A/pt active Search and Examination
- 2003-09-30 US US10/673,250 patent/US7244301B2/en not_active Expired - Fee Related
2007
- 2007-06-13 US US11/762,293 patent/US20070233213A1/en not_active Abandoned
- 2007-06-13 US US11/762,370 patent/US20070232704A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US7244301B2 (en)	2007-07-17
RU2005113277A (ru)	2005-09-20
BR0313954A (pt)	2005-07-19
SE0202895D0 (sv)	2002-09-30
US20070232704A1 (en)	2007-10-04
EP1551468B1 (de)	2008-12-31
DE60325622D1 (de)	2009-02-12
WO2004028577A1 (en)	2004-04-08
AU2003263719A1 (en)	2004-04-19
US20040117030A1 (en)	2004-06-17
EP1551468A1 (de)	2005-07-13
CA2499259A1 (en)	2004-04-08
JP2006504702A (ja)	2006-02-09
ATE419018T1 (de)	2009-01-15
CN100384487C (zh)	2008-04-30
CN1684721A (zh)	2005-10-19
US20070233213A1 (en)	2007-10-04
KR20050071529A (ko)	2005-07-07
KR101100449B1 (ko)	2011-12-29
SE0202895L (sv)	2004-03-31
RU2323014C2 (ru)	2008-04-27

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