SE7402101L - - Google Patents

Info

Publication number
SE7402101L
SE7402101L SE7402101A SE7402101A SE7402101L SE 7402101 L SE7402101 L SE 7402101L SE 7402101 A SE7402101 A SE 7402101A SE 7402101 A SE7402101 A SE 7402101A SE 7402101 L SE7402101 L SE 7402101L
Authority
SE
Sweden
Prior art keywords
formula
compounds
compound
image
radicals
Prior art date
Application number
SE7402101A
Other languages
Unknown language ( )
Other versions
SE418966B (en
Inventor
P B Berntsson
S A I Carlsson
L E Garberg
U K Junggren
S E Sjostrand
Wittken Sundell G W Von
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Priority to SE7402101A priority Critical patent/SE418966B/en
Priority to ZA00750558A priority patent/ZA75558B/en
Priority to DE19752504252 priority patent/DE2504252A1/en
Priority to CH182975A priority patent/CH616160A5/en
Priority to DK54075AA priority patent/DK141122B/en
Priority to CS75987A priority patent/CS194715B2/en
Priority to AU78206/75A priority patent/AU499639B2/en
Priority to SU752106386A priority patent/SU795476A3/en
Priority to DD184221A priority patent/DD119422A5/xx
Priority to FI750421A priority patent/FI59590C/en
Priority to AT113775A priority patent/AT343659B/en
Priority to FR7504888A priority patent/FR2261007B1/fr
Priority to HU75HE00000679A priority patent/HU172141B/en
Priority to CA220,235A priority patent/CA1060448A/en
Priority to IE307/75A priority patent/IE40858B1/en
Priority to LU71872A priority patent/LU71872A1/xx
Priority to NL7501917A priority patent/NL7501917A/en
Priority to GB6869/75A priority patent/GB1500043A/en
Priority to NO750541A priority patent/NO142401C/en
Priority to JP50020284A priority patent/JPS5924157B2/en
Priority to BE153453A priority patent/BE825655A/en
Publication of SE7402101L publication Critical patent/SE7402101L/
Priority to US05/655,246 priority patent/US4045564A/en
Priority to HK670/80A priority patent/HK67080A/en
Priority to SE8101654A priority patent/SE434267B/en
Publication of SE418966B publication Critical patent/SE418966B/en
Priority to MY208/81A priority patent/MY8100208A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)

Abstract

Compounds of the formula I <IMAGE> whose radicals are specified in Patent Claim 1, are obtained by reaction of a compound of the formula IV <IMAGE> containing radicals as in Patent Claim 1, with a compound of the formula V, Z<1>-B-Het, in which B is the group -CH2- or -CH(CH3)- and Z<1> denotes a reactive, esterified hydroxyl group or -SH. The compounds of the formula I can be used for affecting gastric acid secretion of mammals, in particular humans. They are best suited for the treatment, for example, of gastric ulcers or similar disorders.
SE7402101A 1974-02-18 1974-02-18 ANALOGY PROCEDURE FOR THE PREPARATION OF COMPOUNDS WITH Gastric Acid Secretion Inhibitory Effects SE418966B (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
SE7402101A SE418966B (en) 1974-02-18 1974-02-18 ANALOGY PROCEDURE FOR THE PREPARATION OF COMPOUNDS WITH Gastric Acid Secretion Inhibitory Effects
ZA00750558A ZA75558B (en) 1974-02-18 1975-01-27 Gastric acid secretion agents
DE19752504252 DE2504252A1 (en) 1974-02-18 1975-02-01 HETEROCYCLIC COMPOUNDS, METHOD OF PRODUCING THEREOF AND MEDICINAL PRODUCTS CONTAINING THEM
CH182975A CH616160A5 (en) 1974-02-18 1975-02-14 Process for the preparation of novel compounds which affect gastric acid secretion
DK54075AA DK141122B (en) 1974-02-18 1975-02-14 Analogous process for the preparation of substituted benzimidazoles or acid addition salts thereof.
CS75987A CS194715B2 (en) 1974-02-18 1975-02-14 Method of producing new derivatives of 2-/2-heterocyclylmethylthio/benzimidazole
AU78206/75A AU499639B2 (en) 1974-02-18 1975-02-14 Pyridyl benzimidazoles
SU752106386A SU795476A3 (en) 1974-02-18 1975-02-14 Method of preparing derivatives of benzimidazole or their salts
DD184221A DD119422A5 (en) 1974-02-18 1975-02-14
FI750421A FI59590C (en) 1974-02-18 1975-02-14 FOERFARANDE FOER FRAMSTAELLNING AV THERAPEUTIC ACTIVE SUBSTITUTES BENSIMIDAZOLER ELLER SYRAADDITIONSSALTER DAERAV
CA220,235A CA1060448A (en) 1974-02-18 1975-02-17 Gastric acid secretion agents
FR7504888A FR2261007B1 (en) 1974-02-18 1975-02-17
HU75HE00000679A HU172141B (en) 1974-02-18 1975-02-17 Process for preparing 2-/2-pyridyl-methyl-thio/-benzimidazole derivatives
AT113775A AT343659B (en) 1974-02-18 1975-02-17 METHOD FOR PRODUCING NEW BENZIMIDAZOLE DERIVATIVES AND THEIR ACID ADDITION SALTS
IE307/75A IE40858B1 (en) 1974-02-18 1975-02-17 New benzimidazole derivatives,their preparation,and their use in affecting gastric acid secretion
JP50020284A JPS5924157B2 (en) 1974-02-18 1975-02-18 Method for producing new compounds
NL7501917A NL7501917A (en) 1974-02-18 1975-02-18 PHARMACEUTICAL PREPARATION AND HETEROCYCLICAL COMPOUND AND METHOD FOR PREPARING THEM.
GB6869/75A GB1500043A (en) 1974-02-18 1975-02-18 Benzimidazole derivatives their preparation and their use in affecting gastric acid secretion
NO750541A NO142401C (en) 1974-02-18 1975-02-18 ANALOGY PROCEDURE FOR THE PREPARATION OF MACHINE ACID REPRESENTATION 2-PYRIDYLALKYLTIOBENZIMIDAZOLES
LU71872A LU71872A1 (en) 1974-02-18 1975-02-18
BE153453A BE825655A (en) 1974-02-18 1975-02-18 IMPROVEMENTS FOR GASTRIC ACID SECRETION AGENTS
US05/655,246 US4045564A (en) 1974-02-18 1976-02-04 Benzimidazole derivatives useful as gastric acid secretion inhibitors
HK670/80A HK67080A (en) 1974-02-18 1980-11-27 New benzimidazole derivatives, their preparation, and their use in affecting gastric acid secretion
SE8101654A SE434267B (en) 1974-02-18 1981-03-16 ANALOGY PROCEDURE FOR THE PREPARATION OF COMPOUNDS WITH Gastric Acid Secretion Inhibitory Effects
MY208/81A MY8100208A (en) 1974-02-18 1981-12-30 New benzimidazole derivatives,their preparation, and their use in affecting gastric acid secretion

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7402101A SE418966B (en) 1974-02-18 1974-02-18 ANALOGY PROCEDURE FOR THE PREPARATION OF COMPOUNDS WITH Gastric Acid Secretion Inhibitory Effects

Publications (2)

Publication Number Publication Date
SE7402101L true SE7402101L (en) 1975-08-19
SE418966B SE418966B (en) 1981-07-06

Family

ID=20320233

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7402101A SE418966B (en) 1974-02-18 1974-02-18 ANALOGY PROCEDURE FOR THE PREPARATION OF COMPOUNDS WITH Gastric Acid Secretion Inhibitory Effects

Country Status (23)

Country Link
JP (1) JPS5924157B2 (en)
AT (1) AT343659B (en)
AU (1) AU499639B2 (en)
BE (1) BE825655A (en)
CA (1) CA1060448A (en)
CH (1) CH616160A5 (en)
CS (1) CS194715B2 (en)
DD (1) DD119422A5 (en)
DE (1) DE2504252A1 (en)
DK (1) DK141122B (en)
FI (1) FI59590C (en)
FR (1) FR2261007B1 (en)
GB (1) GB1500043A (en)
HK (1) HK67080A (en)
HU (1) HU172141B (en)
IE (1) IE40858B1 (en)
LU (1) LU71872A1 (en)
MY (1) MY8100208A (en)
NL (1) NL7501917A (en)
NO (1) NO142401C (en)
SE (1) SE418966B (en)
SU (1) SU795476A3 (en)
ZA (1) ZA75558B (en)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE416649B (en) * 1974-05-16 1981-01-26 Haessle Ab PROCEDURE FOR THE PREPARATION OF SUBSTANCES WHICH PREVENT Gastric acid secretion
JPS5364103A (en) * 1976-09-24 1978-06-08 Hitachi Ltd Waste heat recovery boiler
IN148930B (en) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (en) * 1978-04-14 1979-10-15 Haessle Ab Gastric acid secretion
US4343805A (en) * 1978-12-16 1982-08-10 John Wyeth & Brother Limited Heterocyclic compounds
AT373888B (en) * 1979-01-10 1984-02-27 Janssen Pharmaceutica Nv METHOD FOR PRODUCING NEW 4-PIPERIDINE AMINES AND THEIR ACID ADDITION SALTS
CH644116A5 (en) * 1980-08-21 1984-07-13 Hoffmann La Roche IMIDAZOLE DERIVATIVES.
DE3047388A1 (en) * 1980-12-16 1982-07-15 Basf Ag, 6700 Ludwigshafen ISATOGEN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS FUNGICIDES
ZA825106B (en) * 1981-08-13 1983-04-27 Haessle Ab Novel pharmaceutical compositions
DE3216843C2 (en) * 1982-05-05 1986-10-23 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3-Thiomethyl-pyridine derivatives, processes for their preparation and pharmaceuticals containing these compounds
US4552886A (en) * 1982-06-07 1985-11-12 Eli Lilly And Company Fungicidal pyridylmethyl-amines
SE8300736D0 (en) * 1983-02-11 1983-02-11 Haessle Ab NOVEL PHARMACOLOGICALLY ACTIVE COMPOUNDS
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
US4503139A (en) * 1983-05-09 1985-03-05 Polaroid Corporation Photographic products and processes and novel compounds
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
US4767770A (en) * 1984-06-18 1988-08-30 Eli Lilly And Company Method of inhibiting aromatase
SE8505112D0 (en) * 1985-10-29 1985-10-29 Haessle Ab NOVEL PHARMACOLOGICAL COMPOUNDS
FR2593178B1 (en) * 1986-01-20 1988-04-29 Esteve Labor Dr 2-BENZIMIDAZOLYLALKYLTHIO (OR SULFINYL OR SULFONYL) DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS.
SE8600658D0 (en) * 1986-02-14 1986-02-14 Haessle Ab NOVEL COMPOSITION OF MATTER
SE8604566D0 (en) * 1986-10-27 1986-10-27 Haessle Ab NOVEL COMPUNDS
NZ234564A (en) 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
SE8604998D0 (en) 1986-11-21 1986-11-21 Haessle Ab NOVEL PHARMACOLOGICAL COMPOUNDS
WO1989005643A1 (en) * 1987-12-18 1989-06-29 Pfizer Inc. Heterocyclic-substituted quinoline-carboxylic acids
JPH021280U (en) * 1988-06-14 1990-01-08
WO1990003373A1 (en) * 1988-09-20 1990-04-05 Hisamitsu Pharmaceutical Co., Inc. NOVEL DIBENZ[b,e]OXEPIN DERIVATIVES
SE8804629D0 (en) 1988-12-22 1988-12-22 Ab Haessle NEW THERAPEUTICALLY ACTIVE COMPOUNDS
IE64199B1 (en) * 1988-12-22 1995-07-12 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
SE8804628D0 (en) 1988-12-22 1988-12-22 Ab Haessle NEW COMPOUNDS
JP2679745B2 (en) * 1989-06-29 1997-11-19 明治製菓株式会社 Azole derivatives and antiulcer agents containing them as active ingredients
JPH0347053U (en) * 1989-09-16 1991-04-30
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US5049674A (en) 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
SE9002206D0 (en) 1990-06-20 1990-06-20 Haessle Ab NEW COMPOUNDS
FI964909L (en) * 1994-06-10 1996-12-09 Byk Gulden Lomberg Chem Fab Substituted arylalkylthioalkylpyridines for combating Helicobacter bacteria
CN1636564A (en) * 1999-08-26 2005-07-13 艾伊法马公司 Composition and pharmaceutical preparation containing alkoxy substituted benzimidazole compound and its preparation method
ES2300599T3 (en) 2002-03-27 2008-06-16 Nycomed Gmbh ALCOXIPIRIDINE DERIVATIVES.
ATE340175T1 (en) 2003-02-25 2006-10-15 Altana Pharma Ag IMIDAZO(4,5-BOEQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF INDUCIBLE NO-SYNTHASE
DE602004014523D1 (en) * 2003-10-01 2008-07-31 Nycomed Gmbh IMIDAZOE4,5-BÜPYRIDINE DERIVATIVES AS INHIBITORS OF INDUCIBLE NO SYNTHASE
JP2007507467A (en) * 2003-10-01 2007-03-29 アルタナ　ファルマ　アクチエンゲゼルシャフト Imidazopyridine derivatives as inducible NO synthase inhibitors
ES2308260T3 (en) 2003-10-01 2008-12-01 Nycomed Gmbh DERIVATIVES OF IMIDAZOPIRIDINS AS INHIBITORS OF INDUCIBLE NON-SYNTHEASE.
BRPI0414873A (en) * 2003-10-01 2006-12-12 Altana Pharma Ag imidazopyridine derivatives as inducible no-synthase inhibitors
US7317021B2 (en) 2003-10-01 2008-01-08 Altana Pharma Ag Aminopyridine-derivatives as inductible no-synthase inhibitors
DK2003130T3 (en) * 2006-03-10 2011-12-12 Arigen Pharmaceuticals Inc New pyridine derivative with anti-helicobacter pylori activity
EP2070923A1 (en) 2007-12-11 2009-06-17 Bayer CropScience AG Insecticide iminoheterocycles
US8969349B2 (en) * 2010-05-26 2015-03-03 Sunovion Pharmaceuticals Inc. Substituted quinoxalines and quinoxalinones as PDE-10 inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234058A (en) * 1968-10-21 1971-06-03

Also Published As

Publication number Publication date
SU795476A3 (en) 1981-01-07
NL7501917A (en) 1975-08-20
DK54075A (en) 1975-10-20
CH616160A5 (en) 1980-03-14
MY8100208A (en) 1981-12-31
NO142401B (en) 1980-05-05
NO750541L (en) 1975-08-19
GB1500043A (en) 1978-02-08
HU172141B (en) 1978-06-28
DK141122B (en) 1980-01-21
FI59590C (en) 1981-09-10
HK67080A (en) 1980-12-05
AU499639B2 (en) 1979-04-26
LU71872A1 (en) 1975-12-09
AU7820675A (en) 1976-08-19
DK141122C (en) 1980-07-07
DD119422A5 (en) 1976-04-20
NO142401C (en) 1980-08-13
JPS50116474A (en) 1975-09-11
CA1060448A (en) 1979-08-14
FI59590B (en) 1981-05-29
DE2504252C2 (en) 1989-02-02
FI750421A7 (en) 1975-08-19
CS194715B2 (en) 1979-12-31
IE40858L (en) 1975-08-18
BE825655A (en) 1975-08-18
FR2261007A1 (en) 1975-09-12
AT343659B (en) 1978-06-12
IE40858B1 (en) 1979-08-29
DE2504252A1 (en) 1975-08-21
ATA113775A (en) 1977-10-15
FR2261007B1 (en) 1978-11-24
ZA75558B (en) 1976-01-28
JPS5924157B2 (en) 1984-06-07
SE418966B (en) 1981-07-06

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