SE7606165L - Aroylering av ettiksyraderivat - Google Patents

Aroylering av ettiksyraderivat

Info

Publication number: SE7606165L
Authority: SE; Sweden
Prior art keywords: formula; alkyl; aroyl; acid derivatives; aroylation
Prior art date: 1975-06-02

Application number

SE7606165A

Other languages

English (en)

Other versions

SE414765B (sv

Inventor

J Carson

Original Assignee

Mcneilab Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-06-02

Filing date

1976-06-01

Publication date

1976-12-03

1976-06-01 Application filed by Mcneilab Inc filed Critical Mcneilab Inc

1976-12-03 Publication of SE7606165L publication Critical patent/SE7606165L/sv

1980-08-18 Publication of SE414765B publication Critical patent/SE414765B/sv

Links

239000002253 acid Substances 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 4
-1 methylthiophenyl Chemical group 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 1
239000000010 aprotic solvent Substances 0.000 abstract 1
239000003054 catalyst Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000006501 nitrophenyl group Chemical group 0.000 abstract 1
150000003233 pyrroles Chemical class 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pyrrole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SE7606165A 1975-06-02 1976-06-01 Forfarande att aroylera l-lagalkylpyrrol-2-ettiksyraderivat i 5-stellning i ett aprotiskt losningsmedel i franvaro av katalysator SE414765B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/583,065 US3998844A (en)	1975-06-02	1975-06-02	Uncatalyzed aroylation of 1-alkylpyrrole-2-acetic acid derivatives

Publications (2)

Publication Number	Publication Date
SE7606165L true SE7606165L (sv)	1976-12-03
SE414765B SE414765B (sv)	1980-08-18

Family

ID=24331553

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7606165A SE414765B (sv)	1975-06-02	1976-06-01	Forfarande att aroylera l-lagalkylpyrrol-2-ettiksyraderivat i 5-stellning i ett aprotiskt losningsmedel i franvaro av katalysator

Country Status (24)

Country	Link
US (1)	US3998844A (sv)
JP (1)	JPS5919536B2 (sv)
AT (1)	AT358572B (sv)
AU (1)	AU497557B2 (sv)
BE (1)	BE842458A (sv)
CA (1)	CA1066297A (sv)
CH (1)	CH603578A5 (sv)
CS (1)	CS220310B2 (sv)
DE (2)	DE2624558A1 (sv)
DK (1)	DK154976C (sv)
ES (1)	ES448408A1 (sv)
FR (1)	FR2313364A1 (sv)
GB (1)	GB1477998A (sv)
HU (1)	HU172047B (sv)
IL (1)	IL49687A (sv)
IN (1)	IN141746B (sv)
NL (1)	NL7605958A (sv)
NZ (1)	NZ180785A (sv)
PL (1)	PL101700B1 (sv)
PT (1)	PT65161B (sv)
RO (1)	RO69252A (sv)
SE (1)	SE414765B (sv)
YU (1)	YU40648B (sv)
ZA (1)	ZA763191B (sv)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4048191A (en) *	1975-06-27	1977-09-13	Mcneil Laboratories, Incorporated	Halo-substituted 1-loweralkyl-5-aroylpyrrole-2-acetic acid compounds
US4207237A (en) *	1977-04-20	1980-06-10	Mcneilab, Inc.	Preparation of pyrrole-2-acetates
US4200645A (en) *	1977-05-10	1980-04-29	Beecham Group Limited	Pyrrole derivatives
US4119639A (en) *	1977-06-27	1978-10-10	Mcneil Laboratories, Incorporated	Preparation of 5-aroylpyrrole-2-acetic acid derivatives
GB1592996A (en) *	1977-10-10	1981-07-15	Rolland Sa A	Acylated pyrrole carboxylic acids and derivatives thereof
JPS5481264A (en) *	1977-12-08	1979-06-28	Sagami Chem Res Center	Preparation of 1-methyl-5-aroylpryrrole-2-acetic acid
SE435278B (sv) *	1977-12-08	1984-09-17	Sagami Chem Res	5-cyano-1-legre(c?711?71-?714)alkyl-pyrrol-2-ettiksyra, framstellning derav och anvendningen som mellanprodukt vid framstellning av terapeutiskt verksamma pyrrolderivat
US4216150A (en) *	1978-10-16	1980-08-05	Mcneil Lab, Inc.	Preparation of pyrrole-2-acetates
US4213905A (en) *	1979-06-25	1980-07-22	Mcneilab, Inc.	Preparation of 5-aroyl-1-loweralkylpyrrole-2-acetic acid salts
US4284562A (en) *	1979-11-27	1981-08-18	Mcneilab, Inc.	Process for preparing pyrrole-2-acetic acids
US4255335A (en) *	1980-04-03	1981-03-10	Mcneilab, Inc.	Preparation of 5-aroyl-1-loweralkylpyrrole-2-acetic acid derivatives
US4299770A (en) *	1980-05-29	1981-11-10	Mallinckrodt, Inc.	Recovery of substituted pyrrole acetate
NZ201468A (en) *	1981-08-10	1986-02-21	Merck & Co Inc	5-aroyl-4-pyrrolyl-alkanoic acid derivatives and pharmaceutical compositions
US5418236A (en) *	1993-12-23	1995-05-23	Ortho Pharmaceutical Corporation	Anxiolytic aroyl piperidinyl and piperazinylacyl pyrroles
US6441194B1 (en)	1999-10-21	2002-08-27	Emory University	Synthesis of 4-substituted pyrrole-2-carbaldehyde compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3752826A (en) *	1970-01-26	1973-08-14	Mcneilab Inc	Aroyl substituted pyrroles
US3846447A (en) *	1972-08-03	1974-11-05	Mcneilab Inc	Preparation of 5-aroyl-pyrroles and intermediates therefor

1975
- 1975-06-02 US US05/583,065 patent/US3998844A/en not_active Expired - Lifetime
1976
- 1976-05-05 IN IN783/CAL/76A patent/IN141746B/en unknown
- 1976-05-05 NZ NZ180785A patent/NZ180785A/xx unknown
- 1976-05-10 GB GB1907276A patent/GB1477998A/en not_active Expired
- 1976-05-14 FR FR7614686A patent/FR2313364A1/fr active Granted
- 1976-05-28 AU AU14405/76A patent/AU497557B2/en not_active Expired
- 1976-05-31 JP JP51062478A patent/JPS5919536B2/ja not_active Expired
- 1976-05-31 PT PT65161A patent/PT65161B/pt unknown
- 1976-05-31 RO RO7686309A patent/RO69252A/ro unknown
- 1976-05-31 ES ES448408A patent/ES448408A1/es not_active Expired
- 1976-05-31 IL IL49687A patent/IL49687A/xx unknown
- 1976-05-31 CA CA253,677A patent/CA1066297A/en not_active Expired
- 1976-06-01 AT AT401476A patent/AT358572B/de not_active IP Right Cessation
- 1976-06-01 BE BE167534A patent/BE842458A/xx not_active IP Right Cessation
- 1976-06-01 DE DE19762624558 patent/DE2624558A1/de not_active Withdrawn
- 1976-06-01 DE DE2624557A patent/DE2624557C2/de not_active Expired
- 1976-06-01 SE SE7606165A patent/SE414765B/sv unknown
- 1976-06-01 CH CH689476A patent/CH603578A5/xx not_active IP Right Cessation
- 1976-06-01 ZA ZA00763191A patent/ZA763191B/xx unknown
- 1976-06-02 NL NL7605958A patent/NL7605958A/xx not_active Application Discontinuation
- 1976-06-02 HU HU76ME00001986A patent/HU172047B/hu unknown
- 1976-06-02 CS CS763662A patent/CS220310B2/cs unknown
- 1976-06-02 PL PL1976190059A patent/PL101700B1/pl unknown
- 1976-06-02 DK DK243676A patent/DK154976C/da active
- 1976-06-02 YU YU1360/76A patent/YU40648B/xx unknown

Also Published As

Publication number	Publication date
JPS5919536B2 (ja)	1984-05-07
PL101700B1 (pl)	1979-01-31
DE2624557A1 (de)	1976-12-23
CA1066297A (en)	1979-11-13
IL49687A0 (en)	1976-07-30
GB1477998A (en)	1977-06-29
CH603578A5 (sv)	1978-08-31
JPS51143664A (en)	1976-12-10
NL7605958A (nl)	1976-12-06
DE2624558A1 (de)	1976-12-23
CS220310B2 (en)	1983-03-25
DK154976C (da)	1989-06-05
HU172047B (hu)	1978-05-28
RO69252A (ro)	1981-08-30
NZ180785A (en)	1978-03-06
FR2313364B1 (sv)	1980-09-12
PT65161A (en)	1976-06-01
ES448408A1 (es)	1977-11-16
FR2313364A1 (fr)	1976-12-31
US3998844A (en)	1976-12-27
SE414765B (sv)	1980-08-18
YU40648B (en)	1986-04-30
PT65161B (en)	1978-07-03
DK154976B (da)	1989-01-16
ZA763191B (en)	1978-01-25
ATA401476A (de)	1980-02-15
AU497557B2 (en)	1978-12-14
BE842458A (fr)	1976-12-01
IN141746B (sv)	1977-04-09
AU1440576A (en)	1977-12-01
AT358572B (de)	1980-09-25
YU136076A (en)	1982-05-31
DK243676A (da)	1976-12-03
IL49687A (en)	1978-10-31
DE2624557C2 (de)	1984-04-05

Legal Events

Date

Code

Title

Description

1995-01-31

NAL

Patent in force

Ref document number: 7606165-4

Format of ref document f/p: F

Publication	Publication Date	Title
SE7606165L (sv)	1976-12-03	Aroylering av ettiksyraderivat
IE43866L (en)	1977-05-07	Piperidine derivatives.
GB1432576A (en)	1976-04-22	Substituted phenylacetic acids
ES446234A1 (es)	1977-10-01	Procedimiento para preparar derivados de acidos quinolonal- canoicos.
IE42216L (en)	1976-02-05	Benzomorphane derivatives
IE44105L (en)	1977-06-04	Imidazolyl-alkyl sulphides
GB1229082A (sv)	1971-04-21
ES410313A2 (es)	1976-01-01	Procedimiento para lapreparacion de 6,7-dimetoxi-quinazoli-nonas.
ES437803A1 (es)	1977-01-01	Procedimiento para la preparacion de derivados de tiofeno.
GB1501795A (en)	1978-02-22	Phenylsulphonyl formamidine derivatives and their preparation and use
GB1504707A (en)	1978-03-22	1-aryl-2-oxo-2,4,5,6,7,7a-hexahydroindoles
ES445322A1 (es)	1977-06-01	Un procedimiento para la preparacion de derivados del acido para-isobutil-fenilacetico.
ES429691A1 (es)	1976-10-01	Proceso para la preparacion del acido p. isobutil-hidratro-pico.
GB1511475A (en)	1978-05-17	Hydrazinopyridazine derivatives having antihypertensive activity
ES430905A1 (es)	1976-10-16	Un procedimiento para la preparacion de derivados de cuma- rina.
GB1378403A (en)	1974-12-27	Process for the preparation of 3-2h-isoquinolones
IE40588L (en)	1975-08-09	3,4-dihydro-2-pyridone derivatives
IE37082L (en)	1973-06-01	2-MERCAPTO-PYRIDO [1, 2-b] 1, 2, 4-THIADIAZOLIUM DERIVATIVES
ES439382A2 (es)	1977-07-01	Un procedimiento para preparacion de nuevos derivados de oxazolopiridinas.
ES461191A1 (es)	1978-06-16	Un procedimiento para la preparacion de nuevos derivados de arilcarboxamida.
GB1282894A (en)	1972-07-26	Process for the manufacture of aminopyrazolones
FR2407924A2 (fr)	1979-06-01	Acides carboxyliques derives de l'indane utilisables notamment comme medicaments
GB1499193A (en)	1978-01-25	Indolino-spiropyran compounds useful as colour formers
IE46358L (en)	1978-06-27	Prostynoic acid derivatives
ES416017A1 (es)	1976-02-16	Un procedimiento para la preparacion de nuevos acidos 2- aroil-pirrol-2-carboxilicos y sus derivados.