SE7610409L - Farmakologiskt aktiva foreningar - Google Patents

Farmakologiskt aktiva foreningar

Info

Publication number: SE7610409L
Authority: SE; Sweden
Prior art keywords: ring; sulphur; bromine; optionally substituted; lower alkyl
Prior art date: 1975-10-02

Application number

SE7610409A

Other languages

English (en)

Other versions

SE431872B (sv

Inventor

T H Brown

J C Emmett

G J Durant

C R Ganellin

Original Assignee

Smith Kline French Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-10-02

Filing date

1976-09-20

Publication date

1977-04-03

1976-09-20 Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab

1977-04-03 Publication of SE7610409L publication Critical patent/SE7610409L/sv

1984-03-05 Publication of SE431872B publication Critical patent/SE431872B/sv

Links

-1 4-imidazolyl ring Chemical group 0.000 abstract 5
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 4
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 4
239000005864 Sulphur Substances 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 4
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 4
229910052794 bromium Inorganic materials 0.000 abstract 4
229910052801 chlorine Inorganic materials 0.000 abstract 4
239000000460 chlorine Substances 0.000 abstract 4
229910052736 halogen Inorganic materials 0.000 abstract 3
150000002367 halogens Chemical class 0.000 abstract 3
125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 2
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
125000001309 chloro group Chemical group Cl* 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
239000001301 oxygen Substances 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
125000005871 1,3-benzodioxolyl group Chemical group 0.000 abstract 1
125000001637 1-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C(*)=C([H])C([H])=C([H])C2=C1[H] 0.000 abstract 1
125000001622 2-naphthyl group Chemical group [H]C1=C([H])C([H])=C2C([H])=C(*)C([H])=C([H])C2=C1[H] 0.000 abstract 1
125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical group O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 1
229940122957 Histamine H2 receptor antagonist Drugs 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000005083 alkoxyalkoxy group Chemical group 0.000 abstract 1
125000005036 alkoxyphenyl group Chemical group 0.000 abstract 1
125000002102 aryl alkyloxo group Chemical group 0.000 abstract 1
125000005059 halophenyl group Chemical group 0.000 abstract 1
239000000938 histamine H1 antagonist Substances 0.000 abstract 1
239000003485 histamine H2 receptor antagonist Substances 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/56—One oxygen atom and one sulfur atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

SE7610409A 1975-10-02 1976-09-20 Analogiforfarande for framstellning av derivat av 4-pyrimidon SE431872B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB4034175		1975-10-02

Publications (2)

Publication Number	Publication Date
SE7610409L true SE7610409L (sv)	1977-04-03
SE431872B SE431872B (sv)	1984-03-05

Family

ID=10414412

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7610409A SE431872B (sv)	1975-10-02	1976-09-20	Analogiforfarande for framstellning av derivat av 4-pyrimidon

Country Status (36)

Country	Link
JP (2)	JPS5246087A (sv)
AR (1)	AR221682A1 (sv)
AT (1)	AT358045B (sv)
AU (1)	AU504897B2 (sv)
BE (1)	BE846452A (sv)
BG (1)	BG25224A3 (sv)
CA (1)	CA1067076A (sv)
CH (1)	CH625801A5 (sv)
CS (1)	CS203003B2 (sv)
DD (1)	DD126563A5 (sv)
DE (1)	DE2643670C2 (sv)
DK (1)	DK442476A (sv)
ES (1)	ES452060A1 (sv)
FI (1)	FI61701C (sv)
FR (1)	FR2326192A1 (sv)
GR (1)	GR61307B (sv)
HU (1)	HU175537B (sv)
IE (1)	IE44845B1 (sv)
IL (1)	IL50503A (sv)
IN (1)	IN146736B (sv)
IT (2)	IT1070839B (sv)
LU (1)	LU75922A1 (sv)
MW (1)	MW3476A1 (sv)
MX (1)	MX4614E (sv)
NL (1)	NL7609917A (sv)
NO (1)	NO145792C (sv)
NZ (1)	NZ181959A (sv)
OA (1)	OA05445A (sv)
PH (1)	PH13921A (sv)
PL (1)	PL105828B1 (sv)
PT (1)	PT65590B (sv)
RO (1)	RO73511A (sv)
SE (1)	SE431872B (sv)
YU (1)	YU237276A (sv)
ZA (1)	ZA765498B (sv)
ZM (1)	ZM12176A1 (sv)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MW5076A1 (en) *	1975-12-29	1978-02-08	Smith Kline French Lab	Pharmacologicalle active compounds
NZ186511A (en)	1977-03-19	1980-11-14	Smith Kline French Lab	3-substituted alkylamino-6-substituted alkyl-1,2,4-triazin-5-ones and pharmaceutical compositions 3-substituted thio-1,2,4-triazin-5-ones
NZ186965A (en)	1977-04-20	1980-02-21	Ici Ltd	Guanidino derivatives and pharmaceutical compositions
US4165378A (en)	1977-04-20	1979-08-21	Ici Americas Inc.	Guanidine derivatives of imidazoles and thiazoles
JPS54104816A (en) *	1978-01-27	1979-08-17	Memorex Corp	Magnetic recorder tape reel
IN151188B (sv) *	1978-02-13	1983-03-05	Smith Kline French Lab
PH16240A (en) *	1978-04-11	1983-08-11	Smith Kline French Lab	Process for making histamine antagonist
ZA792608B (en) *	1978-05-30	1980-06-25	Smith Kline French Lab	Nitro compounds
ZA793443B (en) *	1978-07-26	1980-12-31	Glaxo Group Ltd	Heterocyclic derivatives
US4374836A (en)	1978-10-16	1983-02-22	Imperial Chemical Industries Ltd.	Antisecretory heterocyclic derivatives, process for their manufacture and pharmaceutical compositions containing them
US4496567A (en) *	1978-11-13	1985-01-29	Smith Kline & French Laboratories Limited	Phenyl alkylaminopyrimidones
EP0014057B1 (en)	1979-01-18	1985-01-02	Imperial Chemical Industries Plc	Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them
US4521418A (en) *	1979-02-21	1985-06-04	Smith Kline & French Laboratories Limited	Guanidinothiazolyl derivatives
JPS55145683A (en) *	1979-04-26	1980-11-13	Smith Kline French Lab	Pyrimidone derivative
CA1155842A (en) *	1980-03-29	1983-10-25	Thomas H. Brown	Compounds
ZW21281A1 (en) *	1980-10-01	1981-11-18	Smith Kline French Lab	Amine derivatives
IE53068B1 (en) *	1981-06-15	1988-05-25	Merck & Co Inc	Diamino isothiazole-1-oxides and -1,1-dioxides as gastic secretion inhibitors
PT75074B (en) *	1981-06-27	1986-02-26	Smith Kline French Lab	Process for preparing certain pyrimidone derivatives and compositions containing them
NZ202797A (en) *	1981-12-28	1985-08-30	Lilly Co Eli	Pyrimidine derivatives and pharmaceutical compositions
JPS5993074A (ja) *	1982-10-01	1984-05-29	スミス・クライン・アンド・フレンチ・ラボラトリ−ス・リミテツド	ピリミドン誘導体
DE8309239U1 (de) *	1983-03-29	1983-09-29	Basf Ag, 6700 Ludwigshafen	Bandspule, insbesondere fuer magnetbaender

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1397436A (en) *	1972-09-05	1975-06-11	Smith Kline French Lab	Heterocyclic n-cyanoguinidines
GB1419994A (en) *	1973-05-03	1976-01-07	Smith Kline French Lab	Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them

1976
- 1976-09-06 IN IN1633/CAL/76A patent/IN146736B/en unknown
- 1976-09-07 NL NL7609917A patent/NL7609917A/xx unknown
- 1976-09-07 NZ NZ181959A patent/NZ181959A/xx unknown
- 1976-09-10 MW MW34/76A patent/MW3476A1/xx unknown
- 1976-09-14 PT PT65590A patent/PT65590B/pt unknown
- 1976-09-14 IT IT27192/76A patent/IT1070839B/it active
- 1976-09-14 ZA ZA765498A patent/ZA765498B/xx unknown
- 1976-09-16 IL IL50503A patent/IL50503A/xx unknown
- 1976-09-20 SE SE7610409A patent/SE431872B/sv not_active IP Right Cessation
- 1976-09-22 BE BE170830A patent/BE846452A/xx not_active IP Right Cessation
- 1976-09-24 AT AT711976A patent/AT358045B/de not_active IP Right Cessation
- 1976-09-24 FR FR7628824A patent/FR2326192A1/fr active Granted
- 1976-09-24 PH PH18943A patent/PH13921A/en unknown
- 1976-09-27 CS CS766222A patent/CS203003B2/cs unknown
- 1976-09-28 YU YU02372/76A patent/YU237276A/xx unknown
- 1976-09-28 GR GR51794A patent/GR61307B/el unknown
- 1976-09-28 DE DE2643670A patent/DE2643670C2/de not_active Expired
- 1976-09-28 CA CA262,162A patent/CA1067076A/en not_active Expired
- 1976-09-29 IE IE2154/76A patent/IE44845B1/en unknown
- 1976-09-29 OA OA55946A patent/OA05445A/xx unknown
- 1976-09-30 AR AR264926A patent/AR221682A1/es active
- 1976-09-30 DD DD195067A patent/DD126563A5/xx unknown
- 1976-09-30 AU AU18295/76A patent/AU504897B2/en not_active Expired
- 1976-10-01 NO NO763371A patent/NO145792C/no unknown
- 1976-10-01 MX MX764951U patent/MX4614E/es unknown
- 1976-10-01 DK DK442476A patent/DK442476A/da not_active Application Discontinuation
- 1976-10-01 PL PL1976192809A patent/PL105828B1/pl unknown
- 1976-10-01 CH CH1248276A patent/CH625801A5/de not_active IP Right Cessation
- 1976-10-01 HU HU76SI1543A patent/HU175537B/hu unknown
- 1976-10-01 ZM ZM121/76A patent/ZM12176A1/xx unknown
- 1976-10-01 BG BG034338A patent/BG25224A3/xx unknown
- 1976-10-01 JP JP51118904A patent/JPS5246087A/ja active Granted
- 1976-10-01 FI FI762803A patent/FI61701C/fi not_active IP Right Cessation
- 1976-10-01 ES ES452060A patent/ES452060A1/es not_active Expired
- 1976-10-01 LU LU75922A patent/LU75922A1/xx unknown
- 1976-10-02 RO RO7687887A patent/RO73511A/ro unknown
1978
- 1978-12-11 IT IT7830708A patent/IT7830708A0/it unknown
1980
- 1980-12-09 JP JP55174447A patent/JPS609755B2/ja not_active Expired

Also Published As

Publication number	Publication date
PT65590B (en)	1978-03-28
IL50503A (en)	1980-12-31
AT358045B (de)	1980-08-11
DE2643670C2 (de)	1982-07-01
FI762803A7 (sv)	1977-04-03
ES452060A1 (es)	1977-10-01
FR2326192A1 (fr)	1977-04-29
FI61701C (fi)	1982-09-10
MW3476A1 (en)	1977-11-09
AU1829576A (en)	1978-04-06
CS203003B2 (en)	1981-02-27
JPS5635674B2 (sv)	1981-08-19
CA1067076A (en)	1979-11-27
JPS5246087A (en)	1977-04-12
DE2643670A1 (de)	1977-04-14
SE431872B (sv)	1984-03-05
MX4614E (es)	1982-07-07
PL105828B1 (pl)	1979-11-30
CH625801A5 (en)	1981-10-15
YU237276A (en)	1983-01-21
GR61307B (en)	1978-10-19
FR2326192B1 (sv)	1979-01-12
IT1070839B (it)	1985-04-02
NZ181959A (en)	1978-07-28
AR221682A1 (es)	1981-03-13
DD126563A5 (sv)	1977-07-27
RO73511A (ro)	1981-04-30
NL7609917A (nl)	1977-04-05
JPS5695186A (en)	1981-08-01
NO145792B (no)	1982-02-22
ZM12176A1 (en)	1977-07-21
ATA711976A (de)	1980-01-15
BG25224A3 (bg)	1978-08-10
NO763371L (sv)	1977-04-05
HU175537B (hu)	1980-08-28
FI61701B (fi)	1982-05-31
NO145792C (no)	1982-06-02
PT65590A (en)	1976-10-01
BE846452A (fr)	1977-03-22
JPS609755B2 (ja)	1985-03-12
OA05445A (fr)	1981-03-31
ZA765498B (en)	1977-08-31
IT7830708A0 (it)	1978-12-11
IL50503A0 (en)	1976-11-30
DK442476A (da)	1977-04-03
IE44845B1 (en)	1982-04-21
IE44845L (en)	1977-04-02
IN146736B (sv)	1979-08-25
PH13921A (en)	1980-11-04
AU504897B2 (en)	1979-11-01
LU75922A1 (sv)	1977-05-06

Legal Events

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 7610409-0

Effective date: 19891002

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