SE7707612L - Forfarande for rening av hogremolekylera peptider - Google Patents

Forfarande for rening av hogremolekylera peptider

Info

Publication number
SE7707612L
SE7707612L SE7707612A SE7707612A SE7707612L SE 7707612 L SE7707612 L SE 7707612L SE 7707612 A SE7707612 A SE 7707612A SE 7707612 A SE7707612 A SE 7707612A SE 7707612 L SE7707612 L SE 7707612L
Authority
SE
Sweden
Prior art keywords
purification
hogremolecular
peptider
procedure
buffered solvents
Prior art date
Application number
SE7707612A
Other languages
English (en)
Other versions
SE440507B (sv
Inventor
M Zoltobocki
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of SE7707612L publication Critical patent/SE7707612L/sv
Publication of SE440507B publication Critical patent/SE440507B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/32—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from hydrolysates of wood or straw
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C07K14/625—Extraction from natural sources
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/854—Glands

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Physiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SE7707612A 1976-07-01 1977-06-30 Forfarande for kromatografisk rening av insulin, dess analoger och derivat SE440507B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2629568A DE2629568C3 (de) 1976-07-01 1976-07-01 Verfahren zur Reinigung von Insulin, seinen Analogen und Derivaten

Publications (2)

Publication Number Publication Date
SE7707612L true SE7707612L (sv) 1978-01-02
SE440507B SE440507B (sv) 1985-08-05

Family

ID=5981950

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7707612A SE440507B (sv) 1976-07-01 1977-06-30 Forfarande for kromatografisk rening av insulin, dess analoger och derivat

Country Status (22)

Country Link
US (1) US4129560A (sv)
JP (1) JPS535101A (sv)
AT (1) AT352922B (sv)
AU (1) AU509110B2 (sv)
BE (1) BE856385A (sv)
CA (1) CA1086308A (sv)
CH (1) CH626051A5 (sv)
DE (1) DE2629568C3 (sv)
DK (1) DK149201C (sv)
ES (1) ES460099A1 (sv)
FI (1) FI61490C (sv)
FR (1) FR2356630A1 (sv)
GB (1) GB1582056A (sv)
GR (1) GR78333B (sv)
IE (1) IE44766B1 (sv)
IT (1) IT1080658B (sv)
NL (1) NL188804C (sv)
NO (1) NO145692C (sv)
NZ (1) NZ184516A (sv)
PT (1) PT66751B (sv)
SE (1) SE440507B (sv)
ZA (1) ZA773964B (sv)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4701521A (en) * 1978-07-17 1987-10-20 The Trustees Of Boston University Method of effecting cellular uptake of molecules
US4783441A (en) * 1979-04-30 1988-11-08 Hoechst Aktiengesellschaft Aqueous protein solutions stable to denaturation
US4292041A (en) * 1979-11-02 1981-09-29 Merck & Co., Inc. Surfactant assay
US4459226A (en) * 1982-02-26 1984-07-10 Eli Lilly And Company Process for recovering insulin
US4839341A (en) * 1984-05-29 1989-06-13 Eli Lilly And Company Stabilized insulin formulations
DE3511269A1 (de) * 1985-04-12 1986-10-09 Veb Berlin-Chemie, Ddr 1199 Berlin Verfahren zur reinigung von insulin
JPS6230956A (ja) * 1985-07-31 1987-02-09 Sumitomo Chem Co Ltd 合成ペプチド類に含有されるイオン類の分析法
DE3726655A1 (de) * 1987-08-11 1989-02-23 Hoechst Ag Verfahren zur isolierung basischer proteine aus proteingemischen, welche solche basischen proteine enthalten
JPH07119767B2 (ja) * 1989-03-07 1995-12-20 積水化学工業株式会社 梅毒検査用試薬及びその製造法
DE4028120C2 (de) * 1990-09-05 1996-09-19 Hoechst Ag Verfahren zur Reinigung von Insulin und/oder Insulinderivaten
ES2099193T3 (es) * 1991-12-18 1997-05-16 Hoechst Ag Procedimiento para la obtencion de soluciones con contenido en insulina.
US6444788B1 (en) * 1999-03-15 2002-09-03 Novo Nordisk A/S Ion exchange chromatography of GLP-1, analogs and derivatives thereof
US6451987B1 (en) * 1999-03-15 2002-09-17 Novo Nordisk A/S Ion exchange chromatography of proteins and peptides
PL1664108T3 (pl) * 2003-08-21 2010-03-31 Novo Nordisk As Rozdzielanie polipeptydów zawierających racemizowany aminokwas
US20080096800A1 (en) * 2004-03-12 2008-04-24 Biodel, Inc. Rapid mucosal gel or film insulin compositions
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
US20080085298A1 (en) * 2004-03-12 2008-04-10 Biodel, Inc. Rapid Mucosal Gel or Film Insulin Compositions
US8084420B2 (en) 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
US7713929B2 (en) * 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
WO2007121256A2 (en) 2006-04-12 2007-10-25 Biodel, Inc. Rapid acting and long acting insulin combination formulations
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
AU2012213432B2 (en) 2011-02-01 2016-10-13 Novo Nordisk A/S Purification of insulin
KR20140062044A (ko) 2011-08-25 2014-05-22 에프. 호프만-라 로슈 아게 양이온 및 음이온 교환 크로마토그래피 방법
JP6093364B2 (ja) * 2011-09-30 2017-03-08 ジーイー・ヘルスケア・バイオプロセス・アールアンドディ・アクチボラグ 生体分子の精製方法
CN103130868B (zh) * 2013-03-12 2014-09-17 合肥天麦生物科技发展有限公司 一种蛋白质或多肽的纯化方法
WO2016014325A1 (en) 2014-07-21 2016-01-28 Merck Sharp & Dohme Corp. Chromatography process for purification of inlsulin and insulin analogs
KR20200080748A (ko) * 2018-12-27 2020-07-07 주식회사 폴루스 음이온 교환 크로마토그래피를 이용한 인슐린 전구체의 정제방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3616235A (en) * 1968-05-16 1971-10-26 Forsch Die Garungsindustrie En Process for precipitating enzymes and enzymatic inactive proteins in solution with synthetic tanning materials
US3607858A (en) * 1970-03-31 1971-09-21 American Cyanamid Co Process for preparing lyophilized human blood proteins such as gamma globulin in the presence of a nonionic surfactant
US3683939A (en) * 1970-05-28 1972-08-15 Wilson Pharm & Chem Corp Proteinaceous cosmetic material for hair conditioning
US3907676A (en) * 1970-07-28 1975-09-23 Novo Terapeutisk Labor As Process for purifying insulin
JPS5328989B2 (sv) * 1974-05-27 1978-08-17
US4076800A (en) * 1975-01-13 1978-02-28 The Procter & Gamble Company Protein-containing detergent compositions for protecting keratinous materials

Also Published As

Publication number Publication date
NL188804B (nl) 1992-05-06
IT1080658B (it) 1985-05-16
AT352922B (de) 1979-10-10
FI61490B (fi) 1982-04-30
NL7707037A (nl) 1978-01-03
NO145692B (no) 1982-02-01
FI772023A7 (sv) 1978-01-02
NL188804C (nl) 1992-10-01
GB1582056A (en) 1980-12-31
DE2629568C3 (de) 1981-09-10
DK293277A (da) 1978-01-02
NO145692C (no) 1982-05-12
NZ184516A (en) 1979-10-25
FI61490C (fi) 1982-08-10
IE44766L (en) 1978-01-01
IE44766B1 (en) 1982-03-24
AU509110B2 (en) 1980-04-17
FR2356630B1 (sv) 1983-10-07
CA1086308A (en) 1980-09-23
JPS535101A (en) 1978-01-18
ES460099A1 (es) 1978-05-01
PT66751B (de) 1979-01-22
US4129560A (en) 1978-12-12
JPS6126560B2 (sv) 1986-06-20
SE440507B (sv) 1985-08-05
ATA466377A (de) 1979-03-15
DE2629568B2 (de) 1980-09-04
ZA773964B (en) 1978-05-30
GR78333B (sv) 1984-09-26
FR2356630A1 (fr) 1978-01-27
AU2660477A (en) 1979-01-04
CH626051A5 (sv) 1981-10-30
BE856385A (fr) 1978-01-02
DE2629568A1 (de) 1978-01-12
PT66751A (de) 1977-07-01
DK149201C (da) 1986-08-04
NO772318L (no) 1978-01-03
DK149201B (da) 1986-03-10

Similar Documents

Publication Publication Date Title
ES460099A1 (es) Procedimiento para la purificacion de peptidos de alto peso molecular.
BR7402888D0 (pt) Processo para remocao de despositos proteinaceos de lentes de contato
DK104936C (da) Fremgangsmåde til fremstilling af 2α-cyan-3-oxo-4,4-dialkyl-Δ<5>-androstener eller salte deraf.
BE847153A (fr) Procede de preparation d'acide formique pur,
PT66780A (fr) Procede pour la preparation de derives de l'acide 5-aroil-1,2-dihydro-3h-pirrole(1,2-alpha)pirrole-1-carboxilique
NL183658B (nl) Werkwijze voor de bereiding van waterrijke, zure, vloeibare reinigingsmiddelen.
BE848143A (fr) Procede de preparation de l'acide cis-2-hydroxy-2-phenyl-r-1-cyclohexanecarboxylique,
DE69208556D1 (de) Reinigung von 1,1,1,2-Tetrafluorethan
DK138460B (da) Analogifremgangsmåde til fremstilling af 2beta, 16beta-diamino-3alfa, 17beta-diacyloxy-5alfa-androstanderivater eller syreadditionssalte eller di- eller monokvaternære derivater deraf.
IL43341A0 (en) Process for the recovery of fluorine from an aqueous solution by ion exchange
DK138265B (da) Analogifremgangsmåde til fremstilling af 4,4-diaryl-2-hydroxybutylaminer eller syreadditionssalte eller kvaternære ammoniumsalte deraf.
FR2278634A1 (fr) Procede d'extraction d'ions ammonium de solutions aqueuses par echange avec des zeolites
DK138544B (da) Analogifremgangsmåde til fremstilling af 2beta,6beta,16beta-triamino-3alfa,5alfa,17beta-trihydroxyandrostan-derivater eller syreadditionssalte eller di- eller trikvaternære salte deraf.
AR206208A1 (es) Derivados de acidos 4,4'-bis(1",3",5" triazinil-(2")-amino)estilbeno-2,2'-disulfonicos sustituidos
JPS5224542A (en) Optical system for shaping a beam
DK139973B (da) Analogifremgangsmåde til fremstilling af s-triazolo-(4,3-a)(1,4)-benzodiazepinderivater eller syreadditionssalte deraf.
NL7612546A (nl) Werkwijze ter bereiding van stabiele, ionogene dispersies.
ES450129A1 (es) Procedimiento para la preparacion de fluorhidrato de 3-piri-dil-metanol.
NL7608770A (nl) Werkwijze ter bereiding van (alpha),(alpha),(alpha),(alpha)',(alpha)'-penta- chloor-o-xylenen.
NL7604533A (nl) Werkwijze ter bereiding van perpropionzuuroplos- singen.
SE7609232L (sv) Torkare, serskilt for fordonsglas
BR7305505D0 (pt) Processo para a purificacao de solucoes brutas, aquosas de sorbato de potassio
BR7604051A (pt) Aperfeicoamento em processo para recuperacao de cal de uma solucao aquosa de hipoclorito de calcio
RO79103A (ro) Procedeu de separarea poliarilaminelor din solutii apoase
LU78666A1 (fr) Procede de reduction de l'acide 2,5-dicetogluconique

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7707612-3

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7707612-3

Format of ref document f/p: F