SE7708192L - Sett att framstella androstan-17-on-derivat - Google Patents

Sett att framstella androstan-17-on-derivat

Info

Publication number: SE7708192L
Authority: SE; Sweden
Prior art keywords: derivatives; androstan; produce; way; sterol
Prior art date: 1976-07-16

Application number

SE7708192A

Other languages

English (en)

Other versions

SE440779B (sv

Inventor

A Weber

M Kennecke

H Dahl

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-07-16

Filing date

1977-07-14

Publication date

1978-01-17

1977-07-14 Application filed by Schering Ag filed Critical Schering Ag

1978-01-17 Publication of SE7708192L publication Critical patent/SE7708192L/sv

1985-08-19 Publication of SE440779B publication Critical patent/SE440779B/sv

Links

YJDYCULVYZDESB-HKQXQEGQSA-N (5r,8r,9s,10s,13s,14s)-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one Chemical class C1CCC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC[C@H]21 YJDYCULVYZDESB-HKQXQEGQSA-N 0.000 title 1
229930182558 Sterol Natural products 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
230000004151 fermentation Effects 0.000 abstract 2
238000000855 fermentation Methods 0.000 abstract 2
150000003432 sterols Chemical class 0.000 abstract 2
235000003702 sterols Nutrition 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
244000005700 microbiome Species 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
125000002328 sterol group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/005—Degradation of the lateral chains at position 17
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/863—Mycobacterium

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
General Chemical & Material Sciences (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

SE7708192A 1976-07-16 1977-07-14 Sett att framstella androstan-17-on-derivat SE440779B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19762632677 DE2632677A1 (de)	1976-07-16	1976-07-16	Verfahren zur herstellung von androstan-17-on-derivaten und deren verwendung

Publications (2)

Publication Number	Publication Date
SE7708192L true SE7708192L (sv)	1978-01-17
SE440779B SE440779B (sv)	1985-08-19

Family

ID=5983514

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE7708192A SE440779B (sv)	1976-07-16	1977-07-14	Sett att framstella androstan-17-on-derivat

Country Status (18)

Country	Link
US (1)	US4179336A (sv)
JP (1)	JPS5315493A (sv)
AT (1)	AT363196B (sv)
BE (1)	BE856860A (sv)
CH (3)	CH627190A5 (sv)
CS (1)	CS200517B2 (sv)
DD (4)	DD132439A5 (sv)
DE (1)	DE2632677A1 (sv)
DK (1)	DK142372C (sv)
FR (4)	FR2365588A1 (sv)
GB (1)	GB1585786A (sv)
HU (4)	HU182789B (sv)
IE (1)	IE45304B1 (sv)
IT (1)	IT1077339B (sv)
NL (1)	NL7706638A (sv)
SE (1)	SE440779B (sv)
SU (1)	SU980628A3 (sv)
YU (1)	YU164277A (sv)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55148083A (en) *	1979-05-04	1980-11-18	Mitsubishi Chem Ind Ltd	Microorganism
JPS55150893A (en) *	1979-05-11	1980-11-25	Mitsubishi Chem Ind Ltd	Novel microorganism
JPS578794A (en) *	1980-06-17	1982-01-18	Mitsubishi Chem Ind Ltd	Preparation of androstane-type steroid
US4755463A (en) *	1982-05-25	1988-07-05	Wisconsin Alumni Research Foundation	Process for preparing steroids
US4444884A (en) *	1982-05-25	1984-04-24	Wisconsin Alumni Research Foundation	Process for preparing steroids
DE69621281T2 (de) *	1995-02-28	2002-12-05	Nippon Shokubai Co., Ltd.	Acryl-Säure-Derivate, Verfahren zur Herstellung von Acryl-Säure-Derivaten und Acryl-Säure-Polymere
ES2725808T3 (es) *	2003-05-23	2019-09-27	Nektar Therapeutics	Derivados de PEG que contienen dos cadenas de PEG
CN102656153B (zh) *	2009-10-29	2015-02-18	延世大学校产学协力团	新型血管渗漏阻断剂
WO2012116290A2 (en)	2011-02-25	2012-08-30	Washington University	Neuroactive 17(20)-z-vinylcyano-substituted steroids, prodrugs thereof, and methods of treatment using same
CA3152410A1 (en)	2011-10-14	2013-04-18	Sage Therapeutics, Inc.	3,3-disubstituted 19-nor pregnane compounds, compositions, and uses thereof for the treatment of cns related disorders
TR201808616T4 (tr)	2012-12-18	2018-07-23	Sage Therapeutics Inc	Nöroaktif 19-alkoksi-17-ikameli steroidler, bunların ön ilaçları ve bunları kullanan tedavi yöntemleri.
WO2014127201A1 (en) *	2013-02-15	2014-08-21	Washington University	Neuroactive enantiomeric 15-, 16- and 17-substituted steroids as modulators for gaba type-a receptors
US9512170B2 (en)	2013-03-01	2016-12-06	Washington University	Neuroactive 13, 17-substituted steroids as modulators for GABA type-A receptors
US9365502B2 (en)	2013-03-11	2016-06-14	Washington University	Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors
US9562026B2 (en)	2013-03-14	2017-02-07	Washington University	Neuroactive substituted cyclopent[a]anthracenes as modulators for GABA type-A receptors
RU2019126333A (ru)	2013-04-17	2019-10-08	Сейдж Терапьютикс, Инк.	19-нор нейроактивные стероиды и способы их применения
WO2014169831A1 (en)	2013-04-17	2014-10-23	Sage Therapeutics, Inc.	19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
CN113527400B (zh)	2013-04-17	2024-06-28	萨奇治疗股份有限公司	19-去甲c3,3-二取代的c21-n-吡唑基类固醇及其使用方法
US20160068563A1 (en)	2013-04-17	2016-03-10	Boyd L. Harrison	19-nor neuroactive steroids and methods of use thereof
WO2015010054A2 (en)	2013-07-19	2015-01-22	Sage Therapeutics, Inc.	Neuroactive steroids, compositions, and uses thereof
AU2014308621C1 (en)	2013-08-23	2022-01-06	Sage Therapeutics, Inc.	Neuroactive steroids, compositions, and uses thereof
WO2015195962A1 (en)	2014-06-18	2015-12-23	Sage Therapeutics, Inc.	Neuroactive steroids, compositions, and uses thereof
SMT202000414T1 (it)	2014-10-16	2020-09-10	Sage Therapeutics Inc	Composizioni e metodi per trattare disturbi del snc
MX2021004492A (es)	2014-10-16	2022-12-05	Sage Therapeutics Inc	Composiciones para el tratamiento de trastornos del snc.
ME03749B (me)	2014-11-27	2021-04-20	Sage Therapeutics Inc	KOMPOZICIJE I POSTUPCIZA LEČENJE POREMEĆAJA CNS-a
DK3250210T3 (da)	2015-01-26	2021-03-08	Sage Therapeutics Inc	Sammensætninger og fremgangsmåder til behandling af cns-forstyrrelser
JP6875996B2 (ja)	2015-02-20	2021-05-26	セージセラピューティクス，インコーポレイテッド	神経刺激性ステロイド、組成物、およびその使用
WO2018013613A1 (en)	2016-07-11	2018-01-18	Sage Therapeutics, Inc.	C17, c20, and c21 substituted neuroactive steroids and their methods of use
CA3030420C (en)	2016-07-11	2025-11-18	Sage Therapeutics, Inc.	C7, C12 AND C16 SUBSTITUTED NEUROACTIVE STEROIDS AND ASSOCIATED METHODS OF USE
CN114206900A (zh)	2019-05-31	2022-03-18	萨奇治疗股份有限公司	神经活性类固醇及其组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3451892A (en) *	1965-10-19	1969-06-24	Schering Corp	Process for the preparation of steroidal compounds
NL6705450A (sv) *	1965-10-22	1968-10-21
US3684657A (en) *	1970-05-11	1972-08-15	Searle & Co	Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) *	1970-12-10	1973-09-18	Searle & Co	Selective microbiological preparation of androst-4-ene-3,17-dione
US3738983A (en) *	1971-08-06	1973-06-12	Searle & Co	Process for the preparation of 3-(3beta,17beta-dihydroxyandrost-5-en-17alpha-yl) propionic acid gamma-lactone
DE2534911C2 (de) *	1975-08-01	1985-04-18	Schering AG, 1000 Berlin und 4709 Bergkamen	Verfahren zur Herstellung von 5-Androsten-17-on-Derivaten

1976
- 1976-07-16 DE DE19762632677 patent/DE2632677A1/de active Granted
1977
- 1977-06-16 NL NL7706638A patent/NL7706638A/xx not_active Application Discontinuation
- 1977-07-01 YU YU01642/77A patent/YU164277A/xx unknown
- 1977-07-06 US US05/813,391 patent/US4179336A/en not_active Expired - Lifetime
- 1977-07-12 CH CH861377A patent/CH627190A5/de not_active IP Right Cessation
- 1977-07-13 CS CS774682A patent/CS200517B2/cs unknown
- 1977-07-13 AT AT0504677A patent/AT363196B/de not_active IP Right Cessation
- 1977-07-13 IE IE1456/77A patent/IE45304B1/en unknown
- 1977-07-14 DD DD7700200065A patent/DD132439A5/xx not_active IP Right Cessation
- 1977-07-14 DD DD77206207A patent/DD136142A5/xx unknown
- 1977-07-14 SE SE7708192A patent/SE440779B/sv not_active IP Right Cessation
- 1977-07-14 DD DD77206205A patent/DD136141A5/xx unknown
- 1977-07-14 DD DD77206210A patent/DD137235A5/xx unknown
- 1977-07-15 HU HU8018A patent/HU182789B/hu unknown
- 1977-07-15 GB GB29800/77A patent/GB1585786A/en not_active Expired
- 1977-07-15 DK DK323677A patent/DK142372C/da not_active IP Right Cessation
- 1977-07-15 IT IT25807/77A patent/IT1077339B/it active
- 1977-07-15 SU SU772502698A patent/SU980628A3/ru active
- 1977-07-15 HU HU77SCHE614A patent/HU179344B/hu not_active IP Right Cessation
- 1977-07-15 HU HU8019A patent/HU182790B/hu unknown
- 1977-07-15 HU HU8020A patent/HU182681B/hu unknown
- 1977-07-15 BE BE179384A patent/BE856860A/xx not_active IP Right Cessation
- 1977-07-15 JP JP8493277A patent/JPS5315493A/ja active Granted
- 1977-07-18 FR FR7721932A patent/FR2365588A1/fr active Granted
1978
- 1978-03-07 FR FR7806455A patent/FR2372175A1/fr active Pending
- 1978-03-07 FR FR7806456A patent/FR2372174A1/fr active Pending
- 1978-03-07 FR FR7806457A patent/FR2372176A1/fr active Pending
1981
- 1981-06-23 CH CH415381A patent/CH629503A5/de not_active IP Right Cessation
- 1981-06-23 CH CH415281A patent/CH629222A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
HU179344B (en)	1982-10-28
DE2632677C2 (sv)	1988-06-16
ATA504677A (de)	1980-12-15
FR2372175A1 (fr)	1978-06-23
US4179336A (en)	1979-12-18
FR2365588B1 (sv)	1982-06-25
DK323677A (da)	1978-01-17
IE45304L (en)	1978-01-16
DK142372B (da)	1980-10-20
GB1585786A (en)	1981-03-11
YU164277A (en)	1982-08-31
IE45304B1 (en)	1982-07-28
BE856860A (fr)	1978-01-16
DD136141A5 (de)	1979-06-20
CH627190A5 (sv)	1981-12-31
HU182789B (en)	1984-03-28
DD136142A5 (de)	1979-06-20
CS200517B2 (en)	1980-09-15
JPS5315493A (en)	1978-02-13
CH629222A5 (de)	1982-04-15
AT363196B (de)	1981-07-10
DK142372C (da)	1981-03-23
JPS6117477B2 (sv)	1986-05-07
DD137235A5 (de)	1979-08-22
DE2632677A1 (de)	1978-01-26
SU980628A3 (ru)	1982-12-07
FR2372174A1 (fr)	1978-06-23
HU182790B (en)	1984-03-28
SE440779B (sv)	1985-08-19
CH629503A5 (de)	1982-04-30
FR2365588A1 (fr)	1978-04-21
NL7706638A (nl)	1978-01-18
FR2372176A1 (fr)	1978-06-23
IT1077339B (it)	1985-05-04
HU182681B (en)	1984-02-28
DD132439A5 (de)	1978-09-27

Legal Events

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 7708192-5

Effective date: 19930204

Format of ref document f/p: F

Publication	Publication Date	Title
IE45304L (en)	1978-01-16	Androstan-17-one derivatives.
ES477387A1 (es)	1979-10-16	Procedimiento para preparar derivados de guanidina.
AU554294B2 (en)	1986-08-14	Beta-lactam antibiotics
IE46169L (en)	1978-06-03	Thiazolidine, thiazine and morpholine carboxylic acids and¹esters
ES459412A1 (es)	1978-11-01	Un metodo de preparacion de compuestos heterociclicos deri- vados de hidantoina.
GB2007663A (en)	1979-05-23	Sulphonylated omega - amidinophenyl- alpha -aminocarhoxylic acid amides
GB1476720A (en)	1977-06-16	Substituted cyclohexanes
AU576199B2 (en)	1988-08-18	Beta-carboline derivatives
ES474543A1 (es)	1979-04-16	Procedimiento para producir derivados del acido propionico.
AU5035085A (en)	1986-07-17	Antiallergic 5-alkyl-1-phenyl-2-piperazinoalkyl-pyrazoline- 3-one compounds
ATE23188T1 (de)	1986-11-15	Mn-superoxyddismutase, ihre herstellung und ihre verwendung.
ES433680A1 (es)	1976-12-01	Procedimiento para la preparacion de derivados de arilpipe-razinicos de la adenina.
ES462012A1 (es)	1978-06-01	Un procedimiento para preparar derivados de cefalosporinas.
ES459644A1 (es)	1978-04-01	Un procedimiento para la produccion de un compuesto oxigena-do.
SE7705213L (sv)	1977-11-11	Antikonceptionellt medel
SE7608575L (sv)	1977-02-02	Sett att framstella 5-androsten-17-on-derivat
ES459755A1 (es)	1978-04-01	Procedimiento para preparar carbamatos de oximas de deriva- dos del acido isonitrosocianocetico.
FI844644A0 (fi)	1984-11-27	Framstaellningsfoerfarande foer indanylderivat och deras anvaendning.
KR890004994A (ko)	1989-05-11	신규 백금 착화합물
ES457096A1 (es)	1978-03-01	Procedimiento de preparacion de la n-propargil-piperonilami-na.
GR74870B (sv)	1984-07-12
GB2003866A (en)	1979-03-21	Thiourea derivatives
GB1534242A (en)	1978-11-29	Derivatives of 2-imino-4-thiazolines and thiazolidines
SE8104195L (sv)	1982-08-12	Sett att framstella 3-keto-cyklopenten-5-oxi-derivat
SE7704033L (sv)	1977-10-10	Oxotiaforeningar