SE7713587L - Forfarande for framstellning av oxazolidindionderivat av vinkaalkaloider - Google Patents

Forfarande for framstellning av oxazolidindionderivat av vinkaalkaloider

Info

Publication number: SE7713587L
Authority: SE; Sweden
Prior art keywords: alcoids; vincal; oxazolidin; procedure; preparation
Prior art date: 1976-12-06

Application number

SE7713587A

Other languages

English (en)

Other versions

SE435930B (sv

Inventor

J C Miller

G E Gutowski

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-12-06

Filing date

1977-11-30

Publication date

1978-06-07

1977-11-30 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1978-06-07 Publication of SE7713587L publication Critical patent/SE7713587L/sv

1984-10-29 Publication of SE435930B publication Critical patent/SE435930B/sv

Links

COWNFYYYZFRNOY-UHFFFAOYSA-N oxazolidinedione Chemical class O=C1COC(=O)N1 COWNFYYYZFRNOY-UHFFFAOYSA-N 0.000 title 1
229940122803 Vinca alkaloid Drugs 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Indole Compounds (AREA)

SE7713587A 1976-12-06 1977-11-30 Forfarande for framstellning av ett spirooxazolidindionderivat av vinkaleukoblastin SE435930B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/747,575 US4096148A (en)	1976-12-06	1976-12-06	Oxazolidinedione derivatives of Vinca alkaloids

Publications (2)

Publication Number	Publication Date
SE7713587L true SE7713587L (sv)	1978-06-07
SE435930B SE435930B (sv)	1984-10-29

Family

ID=25005690

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SE7713587A SE435930B (sv)	1976-12-06	1977-11-30	Forfarande for framstellning av ett spirooxazolidindionderivat av vinkaleukoblastin
SE7713586A SE436036B (sv)	1976-12-06	1977-11-30	Analogiforfarande for framstellning av oxazolidindionderivat av vinkaalkaloider

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SE7713586A SE436036B (sv)	1976-12-06	1977-11-30	Analogiforfarande for framstellning av oxazolidindionderivat av vinkaalkaloider

Country Status (31)

Country	Link
US (1)	US4096148A (sv)
JP (1)	JPS5371100A (sv)
AR (1)	AR218467A1 (sv)
AT (2)	AT361638B (sv)
AU (1)	AU513936B2 (sv)
BE (1)	BE861417A (sv)
BG (2)	BG33436A3 (sv)
CA (2)	CA1103664A (sv)
CH (2)	CH634076A5 (sv)
CS (2)	CS195343B2 (sv)
DD (2)	DD134227A5 (sv)
DE (1)	DE2753791A1 (sv)
DK (2)	DK145001C (sv)
ES (2)	ES464764A1 (sv)
FR (1)	FR2372839A1 (sv)
GB (1)	GB1590649A (sv)
GR (2)	GR67244B (sv)
HK (1)	HK57281A (sv)
HU (2)	HU180725B (sv)
IE (1)	IE46105B1 (sv)
IL (1)	IL53506A (sv)
MX (1)	MX4326E (sv)
MY (1)	MY8200176A (sv)
NL (1)	NL7713336A (sv)
NZ (1)	NZ185818A (sv)
PL (2)	PL110671B1 (sv)
PT (2)	PT67343B (sv)
RO (2)	RO75391A (sv)
SE (2)	SE435930B (sv)
SU (2)	SU843753A3 (sv)
ZA (1)	ZA777237B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU181874B (en) *	1977-08-08	1983-11-28	Lilly Co Eli	Process for preparing amides of deacetyl-leurosine and deacetyl-leuroformine
US4357334A (en) *	1980-03-20	1982-11-02	Eli Lilly And Company	Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
US4362664A (en) *	1980-12-29	1982-12-07	Eli Lilly And Company	Vinblastine oxazolidinedione disulfides and related compounds
EP0124502B1 (fr) *	1983-04-29	1991-06-12	OMNICHEM Société anonyme	Nouveaux conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques contenant ces conjugués
HUT76925A (hu) *	1995-04-04	1998-01-28	MTA Enzimológiai Intézet	Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
CA2385528C (en)	1999-10-01	2013-12-10	Immunogen, Inc.	Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT649883A (sv) *	1960-05-24
HU165986B (sv) *	1973-02-16	1974-12-28
AR204004A1 (es) *	1973-04-02	1975-11-12	Lilly Co Eli	Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
US4012390A (en) *	1974-10-16	1977-03-15	Eli Lilly And Company	Vinblastinoic acid

1976
- 1976-12-06 US US05/747,575 patent/US4096148A/en not_active Expired - Lifetime
1977
- 1977-11-30 GB GB49906/77A patent/GB1590649A/en not_active Expired
- 1977-11-30 RO RO7792261A patent/RO75391A/ro unknown
- 1977-11-30 RO RO7792262A patent/RO74137A/ro unknown
- 1977-11-30 CA CA292,072A patent/CA1103664A/en not_active Expired
- 1977-11-30 SE SE7713587A patent/SE435930B/sv not_active IP Right Cessation
- 1977-11-30 PT PT67343A patent/PT67343B/pt unknown
- 1977-11-30 PT PT67342A patent/PT67342B/pt unknown
- 1977-11-30 NZ NZ185818A patent/NZ185818A/xx unknown
- 1977-11-30 CS CS777939A patent/CS195343B2/cs unknown
- 1977-11-30 GR GR54898A patent/GR67244B/el unknown
- 1977-11-30 GR GR54897A patent/GR67243B/el unknown
- 1977-11-30 CS CS777940A patent/CS195344B2/cs unknown
- 1977-11-30 CA CA292,101A patent/CA1082180A/en not_active Expired
- 1977-11-30 SE SE7713586A patent/SE436036B/sv not_active IP Right Cessation
- 1977-12-01 IL IL53506A patent/IL53506A/xx unknown
- 1977-12-01 NL NL7713336A patent/NL7713336A/xx not_active Application Discontinuation
- 1977-12-02 FR FR7736437A patent/FR2372839A1/fr active Granted
- 1977-12-02 JP JP14561377A patent/JPS5371100A/ja active Granted
- 1977-12-02 BG BG037936A patent/BG33436A3/xx unknown
- 1977-12-02 BE BE1008557A patent/BE861417A/xx not_active IP Right Cessation
- 1977-12-02 DE DE19772753791 patent/DE2753791A1/de active Granted
- 1977-12-02 BG BG037937A patent/BG33437A3/bg unknown
- 1977-12-05 MX MX776608U patent/MX4326E/es unknown
- 1977-12-05 IE IE2469/77A patent/IE46105B1/en unknown
- 1977-12-05 AU AU31230/77A patent/AU513936B2/en not_active Expired
- 1977-12-05 ES ES464764A patent/ES464764A1/es not_active Expired
- 1977-12-05 DK DK541077A patent/DK145001C/da not_active IP Right Cessation
- 1977-12-05 HU HU77EI7723A patent/HU180725B/hu not_active IP Right Cessation
- 1977-12-05 AT AT868777A patent/AT361638B/de not_active IP Right Cessation
- 1977-12-05 PL PL1977202659A patent/PL110671B1/pl unknown
- 1977-12-05 CH CH1486177A patent/CH634076A5/de not_active IP Right Cessation
- 1977-12-05 SU SU772549952A patent/SU843753A3/ru active
- 1977-12-05 HU HU77EI771A patent/HU180724B/hu not_active IP Right Cessation
- 1977-12-05 ZA ZA00777237A patent/ZA777237B/xx unknown
- 1977-12-05 CH CH1486277A patent/CH632516A5/de not_active IP Right Cessation
- 1977-12-05 PL PL1977202660A patent/PL106522B1/pl unknown
- 1977-12-05 SU SU772549000A patent/SU865127A3/ru active
- 1977-12-05 ES ES464765A patent/ES464765A1/es not_active Expired
- 1977-12-05 AT AT868877A patent/AT353987B/de not_active IP Right Cessation
- 1977-12-05 DK DK541177A patent/DK144916C/da not_active IP Right Cessation
- 1977-12-06 DD DD77202423A patent/DD134227A5/xx unknown
- 1977-12-06 DD DD77202424A patent/DD134228A5/xx unknown
- 1977-12-06 AR AR270267A patent/AR218467A1/es active
1981
- 1981-11-19 HK HK572/81A patent/HK57281A/xx unknown
1982
- 1982-12-30 MY MY176/82A patent/MY8200176A/xx unknown

Also Published As

Publication number	Publication date
CH634076A5 (de)	1983-01-14
PL110671B1 (en)	1980-07-31
CH632516A5 (de)	1982-10-15
DK541177A (da)	1978-06-07
SE436036B (sv)	1984-11-05
DK145001C (da)	1982-12-27
ES464765A1 (es)	1979-01-01
DK144916C (da)	1982-12-06
JPS5371100A (en)	1978-06-24
IE46105B1 (en)	1983-02-23
MX4326E (es)	1982-03-24
HK57281A (en)	1981-11-27
ES464764A1 (es)	1979-01-01
MY8200176A (en)	1982-12-31
FR2372839B1 (sv)	1981-11-06
BE861417A (fr)	1978-06-02
AU3123077A (en)	1979-06-14
NZ185818A (en)	1979-12-11
DE2753791A1 (de)	1978-06-08
IL53506A0 (en)	1978-03-10
FR2372839A1 (fr)	1978-06-30
CS195343B2 (en)	1980-01-31
PT67342A (en)	1977-12-01
AR218467A1 (es)	1980-06-13
SE435930B (sv)	1984-10-29
DK541077A (da)	1978-06-07
PT67343A (en)	1977-12-01
SU865127A3 (ru)	1981-09-15
HU180724B (en)	1983-04-29
AT353987B (de)	1979-12-10
ATA868877A (de)	1979-05-15
SU843753A3 (ru)	1981-06-30
PL202660A1 (pl)	1978-08-28
HU180725B (en)	1983-04-29
IL53506A (en)	1981-09-13
SE7713586L (sv)	1978-06-07
AT361638B (de)	1981-03-25
DD134227A5 (de)	1979-02-14
ATA868777A (de)	1980-08-15
PL106522B1 (pl)	1979-12-31
GR67244B (sv)	1981-06-25
PT67343B (en)	1979-04-26
AU513936B2 (en)	1981-01-15
BG33436A3 (en)	1983-02-15
DD134228A5 (de)	1979-02-14
IE46105L (en)	1978-06-06
DE2753791C2 (sv)	1990-08-02
PT67342B (en)	1979-04-26
CA1103664A (en)	1981-06-23
RO74137A (ro)	1981-08-30
DK145001B (da)	1982-07-26
PL202659A1 (pl)	1978-12-04
RO75391A (ro)	1980-11-30
US4096148A (en)	1978-06-20
CS195344B2 (en)	1980-01-31
ZA777237B (en)	1979-07-25
CA1082180A (en)	1980-07-22
BG33437A3 (bg)	1983-02-15
NL7713336A (nl)	1978-06-08
GR67243B (sv)	1981-06-25
DK144916B (da)	1982-07-05
GB1590649A (en)	1981-06-03
JPS625160B2 (sv)	1987-02-03

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1995-01-31

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