SE7805949L - Spiroaminderivat och forfarande for framstellning derav och anvendning derav - Google Patents

Spiroaminderivat och forfarande for framstellning derav och anvendning derav

Info

Publication number
SE7805949L
SE7805949L SE7805949A SE7805949A SE7805949L SE 7805949 L SE7805949 L SE 7805949L SE 7805949 A SE7805949 A SE 7805949A SE 7805949 A SE7805949 A SE 7805949A SE 7805949 L SE7805949 L SE 7805949L
Authority
SE
Sweden
Prior art keywords
derivatives
spiroamin
procedures
manufacture
activity
Prior art date
Application number
SE7805949A
Other languages
English (en)
Swedish (sv)
Inventor
K Ono
K Sasajima
J Katsube
H Yamamoto
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of SE7805949L publication Critical patent/SE7805949L/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SE7805949A 1978-02-13 1978-05-24 Spiroaminderivat och forfarande for framstellning derav och anvendning derav SE7805949L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1577878A JPS54109983A (en) 1978-02-13 1978-02-13 Novel spiroamine derivative and its preparation

Publications (1)

Publication Number Publication Date
SE7805949L true SE7805949L (sv) 1979-08-14

Family

ID=11898262

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7805949A SE7805949L (sv) 1978-02-13 1978-05-24 Spiroaminderivat och forfarande for framstellning derav och anvendning derav

Country Status (13)

Country Link
US (1) US4233307A (de)
JP (1) JPS54109983A (de)
AT (1) AT356108B (de)
AU (1) AU511735B2 (de)
BE (1) BE867517A (de)
CA (1) CA1092106A (de)
CH (1) CH635841A5 (de)
DE (1) DE2822227A1 (de)
ES (1) ES470155A1 (de)
FR (1) FR2442845A1 (de)
IT (1) IT7849577A0 (de)
NL (1) NL7805814A (de)
SE (1) SE7805949L (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337260A (en) * 1981-09-10 1982-06-29 Yoshitomi Pharmaceutical Industries, Ltd. Imidazopyridine-spiro-piperidine compounds
IL96507A0 (en) * 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them
AU680020B2 (en) * 1993-06-07 1997-07-17 Merck & Co., Inc. Spiro-substituted azacycles as neurokinin antagonists
US5763471A (en) * 1994-04-07 1998-06-09 Cemaf Melatoninergic agonist spiro indolepyrrolidine! derivatives, process for their preparation and their use as medicinal products
FR2724170B1 (fr) * 1994-09-02 1997-05-30 Cemaf Nouveaux derives de spiro(indole-pyrrolidine) agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament
US5607936A (en) * 1994-09-30 1997-03-04 Merck & Co., Inc. Substituted aryl piperazines as neurokinin antagonists
US5962462A (en) * 1996-12-13 1999-10-05 Merck & Co., Inc. Spiro-substituted azacycles as modulators of chemokine receptor activity
US6013652A (en) * 1997-12-04 2000-01-11 Merck & Co., Inc. Spiro-substituted azacycles as neurokinin antagonists
TR200200118T2 (tr) * 1999-07-21 2002-12-23 Astrazeneca Ab Yeni bileşimler
GB0213715D0 (en) * 2002-06-14 2002-07-24 Syngenta Ltd Chemical compounds
AU2003268512A1 (en) * 2002-09-09 2004-03-29 Janssen Pharmaceutica N.V. Hydroxy alkyl substituted 1,3,8-triazaspiro[4.5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
US7786141B2 (en) * 2004-08-19 2010-08-31 Vertex Pharmaceuticals Incorporated Dihydrospiroindene modulators of muscarinic receptors
KR20070046929A (ko) * 2004-08-19 2007-05-03 버텍스 파마슈티칼스 인코포레이티드 무스카린 수용체 조절제
RU2007124373A (ru) * 2004-11-29 2009-01-10 Вертекс Фармасьютикалз Инкорпорейтед (Us) Модуляторы мускариновых рецептеров
JP2008542375A (ja) * 2005-06-02 2008-11-27 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Ｏｒｌ−１受容体モジュレーターとして有用な新規３−スピロ環式インドリル誘導体
US8193208B2 (en) * 2005-09-09 2012-06-05 Purdue Pharma L.P. Fused and spirocycle compounds and the use thereof
JP2009521483A (ja) * 2005-12-22 2009-06-04 バーテックス ファーマシューティカルズ インコーポレイテッド ムスカリン受容体のモジュレーター
EP1987034B1 (de) * 2006-02-22 2011-07-20 Vertex Pharmceuticals Incorporated Kondensierte spiropiperidine als modulatoren muskarinartiger rezeptoren
AU2007221214A1 (en) * 2006-02-22 2007-09-07 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
CN101500565A (zh) * 2006-06-29 2009-08-05 弗特克斯药品有限公司 毒蕈碱性受体的调节剂
AU2007284548A1 (en) * 2006-08-15 2008-02-21 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
EP2051715A2 (de) * 2006-08-18 2009-04-29 Vertex Pharmceuticals Incorporated Modulatoren muskarinischer rezeptoren
CN101622254B (zh) * 2006-11-28 2013-05-29 詹森药业有限公司 3-(3-氨基-2-(r)-羟基-丙基)-1-(4-氟-苯基)-8-(8-甲基-萘-1-基甲基)-1,3,8-三氮杂-螺[4.5]癸烷-4-酮的盐
MX2009011006A (es) * 2007-04-09 2009-11-02 Janssen Pharmaceutica Nv Derivados de 1,3,8-trisustituido-1,3,8-triaza-espiro[4.5]decano-4- ona como ligandos del receptor de orl-1 para el tratamiento de ansiedad y depresion.
JP5224543B2 (ja) * 2007-05-18 2013-07-03 興和株式会社 新規なスピロオキシインドール化合物及びこれを含有する医薬
US7973162B2 (en) 2007-10-03 2011-07-05 Vertex Pharmaceuticals Incorporated Modulators of muscarinic receptors
KR20240149461A (ko) * 2022-01-18 2024-10-14 메이즈 테라퓨틱스, 인코퍼레이티드 Apol1 저해제 및 사용 방법
WO2025019479A1 (en) * 2023-07-17 2025-01-23 Maze Therapeutics, Inc. Apol1 inhibitors and methods of use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3299075A (en) * 1964-03-12 1967-01-17 Smith Kline French Lab Spiro [3h-indole-3, 3'-pyrrolidine and piperidine] derivatives

Also Published As

Publication number Publication date
JPS54109983A (en) 1979-08-29
BE867517A (fr) 1978-09-18
ES470155A1 (es) 1979-01-01
AU511735B2 (en) 1980-09-04
AT356108B (de) 1980-04-10
ATA388878A (de) 1979-09-15
CA1092106A (en) 1980-12-23
CH635841A5 (de) 1983-04-29
DE2822227A1 (de) 1979-08-16
FR2442845B1 (de) 1981-07-24
FR2442845A1 (fr) 1980-06-27
NL7805814A (nl) 1979-08-15
US4233307A (en) 1980-11-11
AU3616978A (en) 1979-11-22
IT7849577A0 (it) 1978-05-26

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