SE8003317L - Bis(4-demetoxidaunorubicin)dihydrazon-derivat och farmakologiskt acceptabla derivat derav - Google Patents
Bis(4-demetoxidaunorubicin)dihydrazon-derivat och farmakologiskt acceptabla derivat deravInfo
- Publication number
- SE8003317L SE8003317L SE8003317A SE8003317A SE8003317L SE 8003317 L SE8003317 L SE 8003317L SE 8003317 A SE8003317 A SE 8003317A SE 8003317 A SE8003317 A SE 8003317A SE 8003317 L SE8003317 L SE 8003317L
- Authority
- SE
- Sweden
- Prior art keywords
- derivative
- bis
- dihydrazone
- demetoxida
- unorubicin
- Prior art date
Links
- 230000000144 pharmacologic effect Effects 0.000 title 1
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- XDXDZDZNSLXDNA-TZNDIEGXSA-N Idarubicin Chemical compound C1[C@H](N)[C@H](O)[C@H](C)O[C@H]1O[C@@H]1C2=C(O)C(C(=O)C3=CC=CC=C3C3=O)=C3C(O)=C2C[C@@](O)(C(C)=O)C1 XDXDZDZNSLXDNA-TZNDIEGXSA-N 0.000 abstract 1
- XDXDZDZNSLXDNA-UHFFFAOYSA-N Idarubicin Natural products C1C(N)C(O)C(C)OC1OC1C2=C(O)C(C(=O)C3=CC=CC=C3C3=O)=C3C(O)=C2CC(O)(C(C)=O)C1 XDXDZDZNSLXDNA-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229960000908 idarubicin Drugs 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/035,657 US4275192A (en) | 1979-05-03 | 1979-05-03 | Bis(4-demethoxydaunorubicin)dihydrazone derivatives and pharmacologically acceptable salts thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE8003317L true SE8003317L (sv) | 1980-11-04 |
Family
ID=21884000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8003317A SE8003317L (sv) | 1979-05-03 | 1980-05-02 | Bis(4-demetoxidaunorubicin)dihydrazon-derivat och farmakologiskt acceptabla derivat derav |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4275192A (sv) |
| JP (1) | JPS568398A (sv) |
| AU (1) | AU532925B2 (sv) |
| BE (1) | BE883106A (sv) |
| CA (1) | CA1137471A (sv) |
| CH (1) | CH643862A5 (sv) |
| DE (1) | DE3016974A1 (sv) |
| DK (1) | DK194280A (sv) |
| ES (2) | ES8104320A1 (sv) |
| FR (1) | FR2455595A1 (sv) |
| GB (1) | GB2050364B (sv) |
| IE (1) | IE49782B1 (sv) |
| IT (1) | IT1143092B (sv) |
| NL (1) | NL8002577A (sv) |
| SE (1) | SE8003317L (sv) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5162512A (en) * | 1982-03-09 | 1992-11-10 | Cytogen Corporation | Amine derivatives of anthracycline antibodies |
| US4950738A (en) * | 1984-09-13 | 1990-08-21 | Cytogen Corporation | Amine derivatives of anthracycline antibiotics |
| CA1248944A (en) * | 1982-09-28 | 1989-01-17 | Gareth J. Thomas | Anthracycline glycosides |
| FR2551442B1 (fr) * | 1983-09-05 | 1987-04-30 | Centre Nat Rech Scient | Nouveaux derives furaniques, leur preparation et leur application |
| JPS61227590A (ja) * | 1985-04-02 | 1986-10-09 | Microbial Chem Res Found | 新規４′−デメチル−４−エピポドフイロトキシン誘導体 |
| GB2196626B (en) * | 1986-10-15 | 1990-09-19 | Erba Farmitalia | Antitumor anthracycline glycosides, their preparation, intermediates thereof, and compositions and use therefor |
| IL106992A (en) * | 1988-02-11 | 1994-06-24 | Bristol Myers Squibb Co | Acylhydrazone derivatives of anthracycline and methods for their preparation |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3957755A (en) * | 1967-10-18 | 1976-05-18 | Rhone-Poulenc S.A. | Naphthacene derivatives |
| US4112217A (en) * | 1977-09-02 | 1978-09-05 | Sri International | Bis-hydrazones of daunomycin and adriamycin |
| US4125704A (en) * | 1977-09-14 | 1978-11-14 | Sri International | Phenyl-substituted rubidazone analogs |
-
1979
- 1979-05-03 US US06/035,657 patent/US4275192A/en not_active Expired - Lifetime
-
1980
- 1980-04-30 FR FR8009856A patent/FR2455595A1/fr active Granted
- 1980-05-01 DK DK194280A patent/DK194280A/da not_active Application Discontinuation
- 1980-05-02 CA CA000351196A patent/CA1137471A/en not_active Expired
- 1980-05-02 DE DE19803016974 patent/DE3016974A1/de not_active Withdrawn
- 1980-05-02 GB GB8014862A patent/GB2050364B/en not_active Expired
- 1980-05-02 AU AU58039/80A patent/AU532925B2/en not_active Ceased
- 1980-05-02 SE SE8003317A patent/SE8003317L/sv not_active Application Discontinuation
- 1980-05-02 ES ES491116A patent/ES8104320A1/es not_active Expired
- 1980-05-02 NL NL8002577A patent/NL8002577A/nl unknown
- 1980-05-05 IT IT48583/80A patent/IT1143092B/it active
- 1980-05-05 BE BE2/462A patent/BE883106A/fr not_active IP Right Cessation
- 1980-05-05 IE IE912/80A patent/IE49782B1/en unknown
- 1980-05-05 CH CH346980A patent/CH643862A5/de not_active IP Right Cessation
- 1980-05-06 JP JP5985280A patent/JPS568398A/ja active Pending
- 1980-12-16 ES ES497801A patent/ES8200899A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS568398A (en) | 1981-01-28 |
| CA1137471A (en) | 1982-12-14 |
| ES497801A0 (es) | 1981-11-16 |
| ES491116A0 (es) | 1981-04-16 |
| IT8048583A0 (it) | 1980-05-05 |
| ES8104320A1 (es) | 1981-04-16 |
| FR2455595B1 (sv) | 1983-08-12 |
| IT1143092B (it) | 1986-10-22 |
| IE800912L (en) | 1980-11-03 |
| BE883106A (fr) | 1980-11-05 |
| GB2050364A (en) | 1981-01-07 |
| DE3016974A1 (de) | 1980-11-13 |
| AU5803980A (en) | 1980-11-06 |
| DK194280A (da) | 1980-11-04 |
| ES8200899A1 (es) | 1981-11-16 |
| US4275192A (en) | 1981-06-23 |
| AU532925B2 (en) | 1983-10-20 |
| FR2455595A1 (fr) | 1980-11-28 |
| NL8002577A (nl) | 1980-11-05 |
| CH643862A5 (de) | 1984-06-29 |
| GB2050364B (en) | 1983-04-27 |
| IE49782B1 (en) | 1985-12-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI100697B (sv) | Förfarande för framställning av terapeutiskt användbara konjugat för a ntracykliner | |
| ES2055523T3 (es) | Agentes antifungicos de triazol. | |
| ES2053508T3 (es) | Compuestos de acidos 3-pirrolidinil-tio-1-azabiciclo(3.2.0)hept-2-eno-2-carboxilicos. | |
| ATE264295T1 (de) | 7-substituierte kondensierte ring-tetrazyclin- verbindungen | |
| DK0773943T3 (da) | Forbindelser, der er anvendelige som antiproliferative midler og garft-inhibitorer | |
| PT99135A (pt) | Processo para a preparacao de derivados de piperazina | |
| PT1064281E (pt) | Derivados de distamicina benzo-heterociclicos processo para os preparar e a sua utilizacao como agentes antitumorais | |
| SE8003317L (sv) | Bis(4-demetoxidaunorubicin)dihydrazon-derivat och farmakologiskt acceptabla derivat derav | |
| SE7704783L (sv) | Medel for separationsendamal och forfarande for dess framstellning | |
| SE8604950L (sv) | Demensforbettrande och terapeutiska medel | |
| ES2056073T3 (es) | Aril-aralquil-eteres, procedimientos para su preparacion y composicion farmaceutica que los comprende. | |
| SE7704616L (sv) | Sett att framstella nya 11-desoxi-prostaglandin-fÿ2-derivat | |
| ES2038700T3 (es) | Procedimiento para la obtencion de alilmercaptoacetil-sidnoniminas. | |
| ES2038740T3 (es) | Procedimiento de obtencion de compuesos guanidicos que comprenden un ion tetrafenilborato sustituido. | |
| IT1131887B (it) | Glicosidi antraciclinici | |
| SE8501988L (sv) | Iminotiazolidinderivat | |
| GR29903B (el) | Μεθοδος δια την παρασκευην ενωσεων του δις-τριαζινυλαμινο-στιλβεντιου. | |
| ES494257A0 (es) | Procedimiento para la preparacion de una peptidamida | |
| DE69431498D1 (de) | Loracarbef Hydrochlorid C1-C3 Alkohol-Solvate und deren Verwendungen | |
| ES452772A1 (es) | Un procedimiento para la produccion de un dibenzo (b-d)-pi- rano. | |
| GB9315018D0 (en) | Chemical compounds | |
| SE8601013L (sv) | Tricykliska dibensokondenserade derivat och forfarande for deras framstellning | |
| DK104488D0 (da) | Acetamider afledt af 2,3-dihydro-3-phenyl-2-benzofuranon, fremgangsmaader til deres fremstilling og farmaceutiske midler indeholdende dem | |
| MX3286E (es) | Procedimiento para preparar eteres de oxima | |
| PT100104A (pt) | Processo para a preparacao de aminoalcanos substituidos |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 8003317-8 |