SE8007845L - THERAPEUTIC COMPOSITIONS, CONTAINING NEW INDOL- (2,3-A) QUINOLIZIDINES AS ACTIVE INGREDIENTS IN A MIXTURE OF AN ADMINISTRATIVE FORM OF THE LEMPAT - Google Patents

THERAPEUTIC COMPOSITIONS, CONTAINING NEW INDOL- (2,3-A) QUINOLIZIDINES AS ACTIVE INGREDIENTS IN A MIXTURE OF AN ADMINISTRATIVE FORM OF THE LEMPAT

Info

Publication number
SE8007845L
SE8007845L SE8007845A SE8007845A SE8007845L SE 8007845 L SE8007845 L SE 8007845L SE 8007845 A SE8007845 A SE 8007845A SE 8007845 A SE8007845 A SE 8007845A SE 8007845 L SE8007845 L SE 8007845L
Authority
SE
Sweden
Prior art keywords
quinolizidines
lempat
mixture
active ingredients
therapeutic compositions
Prior art date
Application number
SE8007845A
Other languages
Swedish (sv)
Other versions
SE435622B (en
Inventor
Andre Buzas
Original Assignee
Andre Buzas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Andre Buzas filed Critical Andre Buzas
Publication of SE8007845L publication Critical patent/SE8007845L/en
Publication of SE435622B publication Critical patent/SE435622B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)

Abstract

The invention relates to a multistep preparation process of new indolo(2,3-a)quinolizidines of the general formulae (I) and (II): (I) (II) wherein R stands for -COOC2H5, -COOH, -CN, a primary or secondary methylenamino group, a methylenamido group, or wherein R, together with the ring nitrogen of the indolo ring, represents one of the groupings N-CO-NH-CH2 or N-CO. These compounds of the invention are useful in the field of blood circulation in the brain.
SE8007845A 1977-11-25 1980-11-07 THERAPEUTIC COMPOSITION CONTAINING INDOLO (2,3-A) QUINOLIZIDINES SE435622B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4920177 1977-11-25

Publications (2)

Publication Number Publication Date
SE8007845L true SE8007845L (en) 1980-11-07
SE435622B SE435622B (en) 1984-10-08

Family

ID=10451538

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7906287A SE431650B (en) 1977-11-25 1979-07-23 INDOLO (2,3-A) QUINOLIZIDIN AND SET TO MAKE IT
SE8007845A SE435622B (en) 1977-11-25 1980-11-07 THERAPEUTIC COMPOSITION CONTAINING INDOLO (2,3-A) QUINOLIZIDINES

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7906287A SE431650B (en) 1977-11-25 1979-07-23 INDOLO (2,3-A) QUINOLIZIDIN AND SET TO MAKE IT

Country Status (28)

Country Link
JP (1) JPS6147838B2 (en)
AR (1) AR218514A1 (en)
AT (1) AT372384B (en)
AU (1) AU529108B2 (en)
BE (1) BE872134A (en)
CA (1) CA1100959A (en)
CH (1) CH641181A5 (en)
DE (1) DE2851028A1 (en)
DK (1) DK154430C (en)
EG (1) EG13683A (en)
ES (1) ES475328A1 (en)
FI (1) FI64372C (en)
FR (2) FR2409755A1 (en)
HK (1) HK60884A (en)
IE (1) IE47518B1 (en)
IN (1) IN151146B (en)
IT (1) IT1160263B (en)
LU (1) LU80576A1 (en)
MX (1) MX5529E (en)
MY (1) MY8500029A (en)
NL (1) NL7811562A (en)
NO (1) NO151288C (en)
NZ (1) NZ188974A (en)
PT (1) PT68825A (en)
SE (2) SE431650B (en)
SG (1) SG61182G (en)
WO (1) WO1979000319A1 (en)
ZA (1) ZA786426B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3175900D1 (en) * 1981-11-18 1987-03-12 Thal Claude Indoloquinolizine derivatives, process for their preparation and their therapeutic use
FR2529552B1 (en) * 1982-07-05 1985-09-27 Centre Nat Rech Scient NOVEL PROCESS FOR THE PREPARATION OF VINDOLINE SYNTHESIS INTERMEDIATES AND SYNTHESIS INTERMEDIATES
HU191454B (en) * 1984-10-05 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt.,Hu Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
FI95572C (en) 1987-06-22 1996-02-26 Eisai Co Ltd Process for the preparation of a medicament useful as a piperidine derivative or its pharmaceutical salt
KR100324040B1 (en) * 1993-06-18 2002-07-22 후지사와 야꾸힝 고교 가부시키가이샤 Process for preparing novel intermediates and aminopiperazine derivatives for use in synthetic applications
FR2713643B1 (en) * 1993-12-14 1996-06-07 Adir New analogs of eburnane, process for their preparation and pharmaceutical compositions containing them.
FR2713644B1 (en) * 1993-12-14 1996-02-09 Adir New analogs of eburnane, process for their preparation and pharmaceutical compositions containing them.
PT1532391E (en) † 2002-06-24 2009-06-25 Saint Gobain Isover Insulation panel for supply duct
FR2911141B1 (en) * 2007-01-05 2009-02-20 Servier Lab NOVEL TRIAZABENZO [A] NAPHTHO [2,1,8-CDE] AZULENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2911143A1 (en) * 2007-01-05 2008-07-11 Servier Lab Use of neuroprotective compounds to prepare medicaments for treating neurodegenerative diseases
FR2911142A1 (en) * 2007-01-05 2008-07-11 Servier Lab NOVEL AMINOPYRROLO [1,2-A] INDOLE AND AMINOPYRIDAZINO [1,6-A] INDOLE DERIVATIVES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
USD688951S1 (en) 2012-04-04 2013-09-03 Colgate-Palmolive Company Container
USD685271S1 (en) 2012-04-04 2013-07-02 Colgate-Palmolive Company Container
USD685269S1 (en) 2012-04-04 2013-07-02 Colgate-Palmolive Company Container
USD685270S1 (en) 2012-04-04 2013-07-02 Colgate-Palmolive Company Container

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU167366B (en) * 1972-09-06 1975-09-27
BE802387A (en) * 1973-07-16 1973-11-16 Omnium Chimique Sa PROCESS FOR PREPARING VINCAMONE AND EPI-21 VINCAMONE FROM TABERSONIN AND NEW INDOLIC DERIVATIVES.
HU169916B (en) * 1974-09-27 1977-02-28
HU171165B (en) * 1974-11-26 1977-11-28 Richter Gedeon Vegyeszet Process for producing oktahydro-indolo-bracket-2,3-a-bracket closed-quinolizine derivatives
FR2315277A1 (en) * 1975-06-25 1977-01-21 Anvar NEW PENTACYCLIC DERIVATIVES, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
MY8500029A (en) 1985-12-31
CH641181A5 (en) 1984-02-15
IT1160263B (en) 1987-03-11
IT7830171A0 (en) 1978-11-24
FR2409755B1 (en) 1980-08-01
AU529108B2 (en) 1983-05-26
BE872134A (en) 1979-03-16
ATA837478A (en) 1983-02-15
EG13683A (en) 1982-09-30
CA1100959A (en) 1981-05-12
FR2423492A1 (en) 1979-11-16
MX5529E (en) 1983-09-23
SE431650B (en) 1984-02-20
FI64372C (en) 1983-11-10
DK154430C (en) 1989-04-17
FI783581A7 (en) 1979-05-26
DK154430B (en) 1988-11-14
LU80576A1 (en) 1979-03-22
DE2851028A1 (en) 1979-05-31
DE2851028C2 (en) 1990-05-03
SE7906287L (en) 1979-07-23
NO151288C (en) 1985-03-13
NL7811562A (en) 1979-05-29
PT68825A (en) 1978-12-01
ZA786426B (en) 1979-10-31
JPS54500053A (en) 1979-11-08
AU4187478A (en) 1979-05-31
IE47518B1 (en) 1984-04-04
HK60884A (en) 1984-08-10
SE435622B (en) 1984-10-08
IE782328L (en) 1979-05-25
JPS6147838B2 (en) 1986-10-21
NO151288B (en) 1984-12-03
SG61182G (en) 1985-02-15
NO783958L (en) 1979-05-28
AR218514A1 (en) 1980-06-13
FR2409755A1 (en) 1979-06-22
ES475328A1 (en) 1979-04-01
AT372384B (en) 1983-09-26
WO1979000319A1 (en) 1979-06-14
IN151146B (en) 1983-02-26
FI64372B (en) 1983-07-29
DK524978A (en) 1979-05-26
NZ188974A (en) 1989-10-27
FR2423492B1 (en) 1980-12-05

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