SE8201701L - Forfarande for framstellning av en cefemforenig i kristalliserad form - Google Patents

Forfarande for framstellning av en cefemforenig i kristalliserad form

Info

Publication number
SE8201701L
SE8201701L SE8201701A SE8201701A SE8201701L SE 8201701 L SE8201701 L SE 8201701L SE 8201701 A SE8201701 A SE 8201701A SE 8201701 A SE8201701 A SE 8201701A SE 8201701 L SE8201701 L SE 8201701L
Authority
SE
Sweden
Prior art keywords
preparing
procedure
cefem compound
phenylacetamido
cephem
Prior art date
Application number
SE8201701A
Other languages
English (en)
Other versions
SE443564B (sv
Inventor
Kuo Shang Yang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SE8201701L publication Critical patent/SE8201701L/sv
Publication of SE443564B publication Critical patent/SE443564B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (1)

Patentkrav
1. lobrfarande far framstallning av dot kristalliserade metanolatet av natrium-7-(0-2-hydroxi-2-feny1acetamido)-3-(1-mety1-1H-tetrazo1-5- -y1tiomety1)-3-cefem-4-karboxy1at,kannetecknat av att namnda metanolat beredes av 7-( :1-2-1ydroxi-2-feny1acetamido)-3-(1- -metyl-1H-tetrazol-5-yltiomety1)-3-cefem-4-karbonsyra, netanol och natriumsaltet av en svag syra vid en temperatur mellan ca 0 och 50°C.
SE8201701A 1975-12-22 1982-03-17 Kristallint metanolat av natriumcefamandol till anvendning vid framstellning av kristallint anhydrat av natriumcefamandol och forfarande for framstellning derav SE443564B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/642,922 US4054738A (en) 1975-12-22 1975-12-22 Sodium cefamandole crystalline forms

Publications (2)

Publication Number Publication Date
SE8201701L true SE8201701L (sv) 1982-03-17
SE443564B SE443564B (sv) 1986-03-03

Family

ID=24578600

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7614401A SE424730B (sv) 1975-12-22 1976-12-21 Forfarande for framstellning av natriumcefamandolanhydrat i kristalliserad form
SE8201702A SE441096B (sv) 1975-12-22 1982-03-17 Forfarande for framstellning av natrium cefamandolanhydrat i kristalliserad form
SE8201701A SE443564B (sv) 1975-12-22 1982-03-17 Kristallint metanolat av natriumcefamandol till anvendning vid framstellning av kristallint anhydrat av natriumcefamandol och forfarande for framstellning derav

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SE7614401A SE424730B (sv) 1975-12-22 1976-12-21 Forfarande for framstellning av natriumcefamandolanhydrat i kristalliserad form
SE8201702A SE441096B (sv) 1975-12-22 1982-03-17 Forfarande for framstellning av natrium cefamandolanhydrat i kristalliserad form

Country Status (31)

Country Link
US (1) US4054738A (sv)
JP (2) JPS5282714A (sv)
AR (1) AR213300A1 (sv)
AT (2) AT348678B (sv)
AU (1) AU505924B2 (sv)
BE (1) BE849415A (sv)
CA (1) CA1080696A (sv)
CH (1) CH628348A5 (sv)
CS (1) CS195746B2 (sv)
DD (1) DD128727A5 (sv)
DE (1) DE2654647C2 (sv)
DK (1) DK153156C (sv)
FI (1) FI66008C (sv)
FR (3) FR2361898A1 (sv)
GB (1) GB1565854A (sv)
GR (1) GR65891B (sv)
HU (1) HU172474B (sv)
IL (3) IL50977A (sv)
LU (1) LU76435A1 (sv)
MX (1) MX3840E (sv)
NL (1) NL187483C (sv)
NO (1) NO148887C (sv)
NZ (1) NZ182694A (sv)
OA (1) OA05518A (sv)
PH (1) PH12191A (sv)
PL (1) PL102739B1 (sv)
PT (1) PT65955B (sv)
RO (3) RO75964A (sv)
SE (3) SE424730B (sv)
SU (3) SU637087A3 (sv)
ZA (1) ZA766957B (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168376A (en) * 1978-06-05 1979-09-18 Eli Lilly And Company Process for crystalline sodium cefamandole
US4237279A (en) * 1979-07-27 1980-12-02 Eli Lilly And Company Crystalline 3-hydroxycephalosporin solvates
DE3313816A1 (de) * 1983-04-16 1984-10-18 Hoechst Ag, 6230 Frankfurt Neue kristallmodifikation von ceftazidim
DE3313818A1 (de) * 1983-04-16 1984-10-18 Hoechst Ag, 6230 Frankfurt Neue kristallmodifikation von ceftazidim
CA1242699A (en) * 1985-02-01 1988-10-04 Bristol-Myers Company Cefbuperazone and derivatives thereof
JPH0677412B2 (ja) * 1985-05-03 1994-09-28 株式会社フジクラ 高圧直流送電用電力ケーブル
JPS629495U (sv) * 1985-07-01 1987-01-21
GB9717629D0 (en) 1997-08-21 1997-10-22 Johnson Matthey Plc Removal of residual organic solvents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496171A (en) * 1969-02-17 1970-02-17 Lilly Co Eli Process for improving the physical and chemical properties of cephaloglycin
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
US3692781A (en) * 1971-02-26 1972-09-19 Glaxo Lab Ltd Recovery of pure cephalexin from acidic reaction mixtures
US3819620A (en) * 1972-06-01 1974-06-25 Squibb & Sons Inc 7-(d-alpha-amino-1,4-cyclohexadien-1-ylacet-amido)desacetoxycephalosporanic acid dihydrate
US3862186A (en) * 1972-12-15 1975-01-21 Bristol Myers Co Process for the production of cephalexin monohydrate
US3928592A (en) * 1974-02-22 1975-12-23 Lilly Co Eli Antibiotic pharmaceutical compositions

Also Published As

Publication number Publication date
FR2351984A1 (fr) 1977-12-16
FR2361898B1 (sv) 1980-03-14
HU172474B (hu) 1978-09-28
ATA948976A (de) 1978-07-15
IL50977A (en) 1980-02-29
FR2361898A1 (fr) 1978-03-17
DK153156C (da) 1989-02-20
MX3840E (es) 1981-08-11
CS195746B2 (en) 1980-02-29
AU505924B2 (en) 1979-12-06
RO69709A (ro) 1980-04-15
ZA766957B (en) 1978-06-28
SE7614401L (sv) 1977-06-23
FR2351985B1 (sv) 1980-06-27
CA1080696A (en) 1980-07-01
RO75963A (ro) 1981-02-28
AT348678B (de) 1979-02-26
SU1018585A3 (ru) 1983-05-15
DE2654647A1 (de) 1977-06-30
FR2351985A1 (fr) 1977-12-16
BE849415A (fr) 1977-06-15
AT349148B (de) 1979-03-26
PL102739B1 (pl) 1979-04-30
SU671732A3 (ru) 1979-06-30
SU637087A3 (ru) 1978-12-05
IL50977A0 (en) 1977-01-31
GR65891B (sv) 1980-12-01
AR213300A1 (es) 1979-01-15
FI763682A7 (sv) 1977-06-23
JPS61351B2 (sv) 1986-01-08
PH12191A (en) 1978-11-21
CH628348A5 (de) 1982-02-26
IL57387A0 (en) 1979-09-30
FI66008C (fi) 1984-08-10
JPS5282714A (en) 1977-07-11
LU76435A1 (sv) 1977-06-10
NZ182694A (en) 1978-09-25
US4054738A (en) 1977-10-18
NO148887C (no) 1984-01-04
SE424730B (sv) 1982-08-09
DE2654647C2 (de) 1982-06-24
DD128727A5 (de) 1977-12-07
OA05518A (fr) 1981-04-30
AU2001376A (en) 1978-06-01
FI66008B (fi) 1984-04-30
SE443564B (sv) 1986-03-03
GB1565854A (en) 1980-04-23
NL7614233A (nl) 1977-06-24
SE441096B (sv) 1985-09-09
JPS6183189A (ja) 1986-04-26
IL57386A0 (en) 1979-09-30
NL187483B (nl) 1991-05-16
ATA217578A (de) 1978-08-15
DK575576A (da) 1977-06-23
NO764222L (sv) 1977-06-23
NO148887B (no) 1983-09-26
RO75964A (ro) 1981-02-28
FR2351984B1 (sv) 1980-06-27
PT65955B (en) 1978-06-15
PT65955A (en) 1977-01-01
JPS624393B2 (sv) 1987-01-30
NL187483C (nl) 1991-10-16
DK153156B (da) 1988-06-20
SE8201702L (sv) 1982-03-17

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