SE8302643L - Analoger av neurohypofyshormoner med inhiberande egenskaper - Google Patents
Analoger av neurohypofyshormoner med inhiberande egenskaperInfo
- Publication number
- SE8302643L SE8302643L SE8302643A SE8302643A SE8302643L SE 8302643 L SE8302643 L SE 8302643L SE 8302643 A SE8302643 A SE 8302643A SE 8302643 A SE8302643 A SE 8302643A SE 8302643 L SE8302643 L SE 8302643L
- Authority
- SE
- Sweden
- Prior art keywords
- analogues
- residue
- group
- hydrogen
- series
- Prior art date
Links
- 230000002401 inhibitory effect Effects 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229940024606 amino acid Drugs 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 229940088597 hormone Drugs 0.000 abstract 2
- 239000005556 hormone Substances 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 230000005764 inhibitory process Effects 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 150000008574 D-amino acids Chemical class 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 abstract 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 abstract 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 abstract 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- -1 aromatic amino acid Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- BEBCJVAWIBVWNZ-UHFFFAOYSA-N glycinamide Chemical group NCC(N)=O BEBCJVAWIBVWNZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229960000310 isoleucine Drugs 0.000 abstract 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 abstract 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
- 230000003191 uterotonic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/16—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS823340A CS226923B1 (cs) | 1982-05-10 | 1982-05-10 | Analogy oxytocínu s inhibičnlm účinkem a způsob jejicb výroby |
| CS620582A CS229895B1 (cs) | 1982-08-26 | 1982-08-26 | Analog oxytocinu a způsob jeho výroby |
| CS620482A CS229894B1 (cs) | 1982-08-26 | 1982-08-26 | Analog vasopresinu a způsob jeho výroby |
| CS627182A CS230327B1 (en) | 1982-08-27 | 1982-08-27 | Oxytocine analogue and method of preparing same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8302643D0 SE8302643D0 (sv) | 1983-05-09 |
| SE8302643L true SE8302643L (sv) | 1983-11-11 |
| SE460051B SE460051B (sv) | 1989-09-04 |
Family
ID=27430101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8302643A SE460051B (sv) | 1982-05-10 | 1983-05-09 | Analoger av neurohypofyshormoner med inhiberande egenskaper |
Country Status (9)
| Country | Link |
|---|---|
| BE (1) | BE896685A (sv) |
| CH (1) | CH653346A5 (sv) |
| DE (1) | DE3317092A1 (sv) |
| DK (1) | DK199983A (sv) |
| FR (1) | FR2526318B1 (sv) |
| GB (1) | GB2121052B (sv) |
| IT (1) | IT1164212B (sv) |
| NL (1) | NL8301663A (sv) |
| SE (1) | SE460051B (sv) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT398767B (de) * | 1988-05-26 | 1995-01-25 | Gebro Broschek Gmbh | Verfahren zur reinigung eines rohpeptids mittels präparativer mitteldruckflüssigkeitschromatographie |
| JP2003335797A (ja) * | 2000-06-28 | 2003-11-28 | Daicel Chem Ind Ltd | ペプチド化合物及びそれを有効成分とする医薬組成物 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS216722B1 (en) * | 1980-06-24 | 1982-11-26 | Michal Lebl | Oxytocine analogues and method of making the same |
-
1983
- 1983-05-05 DK DK199983A patent/DK199983A/da not_active Application Discontinuation
- 1983-05-05 GB GB08312320A patent/GB2121052B/en not_active Expired
- 1983-05-06 BE BE0/210719A patent/BE896685A/fr not_active IP Right Cessation
- 1983-05-09 FR FR8307696A patent/FR2526318B1/fr not_active Expired
- 1983-05-09 CH CH2530/83A patent/CH653346A5/de not_active IP Right Cessation
- 1983-05-09 IT IT21002/83A patent/IT1164212B/it active
- 1983-05-09 SE SE8302643A patent/SE460051B/sv not_active IP Right Cessation
- 1983-05-10 DE DE19833317092 patent/DE3317092A1/de not_active Withdrawn
- 1983-05-10 NL NL8301663A patent/NL8301663A/nl not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2526318A1 (fr) | 1983-11-10 |
| IT1164212B (it) | 1987-04-08 |
| GB8312320D0 (en) | 1983-06-08 |
| FR2526318B1 (fr) | 1986-11-14 |
| GB2121052B (en) | 1985-08-14 |
| IT8321002A0 (it) | 1983-05-09 |
| IT8321002A1 (it) | 1984-11-09 |
| NL8301663A (nl) | 1983-12-01 |
| BE896685A (fr) | 1983-09-01 |
| CH653346A5 (de) | 1985-12-31 |
| SE460051B (sv) | 1989-09-04 |
| DK199983A (da) | 1983-11-11 |
| DK199983D0 (da) | 1983-05-05 |
| GB2121052A (en) | 1983-12-14 |
| SE8302643D0 (sv) | 1983-05-09 |
| DE3317092A1 (de) | 1983-11-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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