SE8401609L - Forfarande for framstellning av azinometyl-rifamyciner - Google Patents
Forfarande for framstellning av azinometyl-rifamycinerInfo
- Publication number
- SE8401609L SE8401609L SE8401609A SE8401609A SE8401609L SE 8401609 L SE8401609 L SE 8401609L SE 8401609 A SE8401609 A SE 8401609A SE 8401609 A SE8401609 A SE 8401609A SE 8401609 L SE8401609 L SE 8401609L
- Authority
- SE
- Sweden
- Prior art keywords
- alkyl
- ring
- alkenyl
- cycloalkyl
- image
- Prior art date
Links
- 125000003342 alkenyl group Chemical group 0.000 abstract 4
- -1 C2-C4 cloro- Chemical group 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 125000006701 (C1-C7) alkyl group Chemical group 0.000 abstract 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 2
- BTVYFIMKUHNOBZ-ZDHWWVNNSA-N Rifamycin S Natural products COC1C=COC2(C)Oc3c(C)c(O)c4C(=O)C(=CC(=O)c4c3C2=O)NC(=O)C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(=O)C)C1C)C BTVYFIMKUHNOBZ-ZDHWWVNNSA-N 0.000 abstract 2
- BTVYFIMKUHNOBZ-ODRIEIDWSA-N Rifamycin S Chemical compound O=C1C(C(O)=C2C)=C3C(=O)C=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O BTVYFIMKUHNOBZ-ODRIEIDWSA-N 0.000 abstract 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- SCYULBFZEHDVBN-UHFFFAOYSA-N 1,1-Dichloroethane Chemical compound CC(Cl)Cl SCYULBFZEHDVBN-UHFFFAOYSA-N 0.000 abstract 1
- 125000004605 1,2,3,4-tetrahydroisoquinolinyl group Chemical group C1(NCCC2=CC=CC=C12)* 0.000 abstract 1
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000004634 hexahydroazepinyl group Chemical group N1(CCCCCC1)* 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000002757 morpholinyl group Chemical group 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract 1
- 229940081192 rifamycins Drugs 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838308166A GB8308166D0 (en) | 1983-03-24 | 1983-03-24 | Preparation of azinomethyl-rifamycins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8401609D0 SE8401609D0 (sv) | 1984-03-22 |
| SE8401609L true SE8401609L (sv) | 1984-09-25 |
| SE456586B SE456586B (sv) | 1988-10-17 |
Family
ID=10540154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8401609A SE456586B (sv) | 1983-03-24 | 1984-03-22 | Forfarande for framstellning av azinometyl-rifamyciner |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4507295A (sv) |
| JP (1) | JPS59176291A (sv) |
| AT (1) | AT384024B (sv) |
| AU (1) | AU557393B2 (sv) |
| BE (1) | BE899211A (sv) |
| CA (1) | CA1204740A (sv) |
| CH (1) | CH660009A5 (sv) |
| DE (1) | DE3410102A1 (sv) |
| DK (1) | DK157874C (sv) |
| FI (1) | FI78104C (sv) |
| FR (1) | FR2543141B1 (sv) |
| GB (2) | GB8308166D0 (sv) |
| GR (1) | GR81481B (sv) |
| HU (1) | HU189073B (sv) |
| IL (1) | IL71273A (sv) |
| IT (1) | IT1206141B (sv) |
| NL (1) | NL8400935A (sv) |
| SE (1) | SE456586B (sv) |
| SU (1) | SU1486065A3 (sv) |
| ZA (1) | ZA842135B (sv) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8408924D0 (en) * | 1984-04-06 | 1984-05-16 | Dobfar Spa | 3-azinomethyl rifamycins |
| US4916126A (en) * | 1987-09-25 | 1990-04-10 | Ciba-Geigy Corporation | Diacyl derivatives of 4-(trialkylbenzyl)-piperazinyl compounds |
| GB9221220D0 (en) * | 1992-10-09 | 1992-11-25 | Sandoz Ag | Organic componds |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1795568C3 (de) * | 1964-07-31 | 1974-07-18 | Gruppo Lepetit S.P.A., Mailand (Italien) | 3-Hydroxymethyl-rifamycin SV und Verfahren zu seiner Herstellung. Ausscheidung aus: 1595883 |
| FR208F (sv) * | 1964-07-31 | |||
| NL145554B (nl) * | 1967-06-07 | 1975-04-15 | Lepetit Spa | Werkwijze voor het bereiden van een 3-formylrifamycine sv-derivaat |
| AR207762A1 (es) * | 1973-07-25 | 1976-10-29 | Archifar Ind Chim Trentino | Procedimiento para la preparacion de 3-((4-metil-1-piperazin-1-il)-imino)-metil-rifamicina sv o rifampicina |
| GB1594134A (en) * | 1977-11-25 | 1981-07-30 | Holco Investment Inc | Rifamycins |
| BE886395A (fr) * | 1980-02-13 | 1981-03-16 | Erba Farmitalia | Derives de rifamycine |
| IT1135270B (it) * | 1980-04-12 | 1986-08-20 | Erba Farmitalia | 3-amidino-ansamicine |
| US4447432A (en) * | 1981-11-17 | 1984-05-08 | Farmitalia Carlo Erba S.P.A. | Azino rifamycins |
| DE3239751A1 (de) * | 1982-10-27 | 1984-05-03 | Farmitalia Carlo Erba S.p.A., Mailand / Milano | Verfahren zur herstellen von azino-rifamycin-verbindungen |
| BE895041A (fr) * | 1982-11-17 | 1983-05-17 | Erba Farmitalia | Procede de preparation de composes d'azino-rifamycines |
-
1983
- 1983-03-24 GB GB838308166A patent/GB8308166D0/en active Pending
-
1984
- 1984-02-29 DK DK133784A patent/DK157874C/da not_active IP Right Cessation
- 1984-03-16 FI FI841078A patent/FI78104C/sv not_active IP Right Cessation
- 1984-03-16 CA CA000449790A patent/CA1204740A/en not_active Expired
- 1984-03-16 AT AT0089884A patent/AT384024B/de not_active IP Right Cessation
- 1984-03-19 GR GR74151A patent/GR81481B/el unknown
- 1984-03-19 US US06/590,649 patent/US4507295A/en not_active Expired - Fee Related
- 1984-03-19 IL IL71273A patent/IL71273A/xx unknown
- 1984-03-19 AU AU25850/84A patent/AU557393B2/en not_active Ceased
- 1984-03-19 JP JP59051286A patent/JPS59176291A/ja active Granted
- 1984-03-19 GB GB08407084A patent/GB2139619B/en not_active Expired
- 1984-03-20 CH CH1395/84A patent/CH660009A5/it not_active IP Right Cessation
- 1984-03-20 DE DE19843410102 patent/DE3410102A1/de active Granted
- 1984-03-20 FR FR8404259A patent/FR2543141B1/fr not_active Expired
- 1984-03-21 BE BE0/212602A patent/BE899211A/fr not_active IP Right Cessation
- 1984-03-22 IT IT8420191A patent/IT1206141B/it active
- 1984-03-22 ZA ZA842135A patent/ZA842135B/xx unknown
- 1984-03-22 SE SE8401609A patent/SE456586B/sv not_active IP Right Cessation
- 1984-03-22 SU SU843717072A patent/SU1486065A3/ru active
- 1984-03-23 NL NL8400935A patent/NL8400935A/nl not_active Application Discontinuation
- 1984-03-23 HU HU841167A patent/HU189073B/hu not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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