SE8504659L - Forfarande for framstellning av n?72-substituerade derivat av mitomucin c - Google Patents

Forfarande for framstellning av n?72-substituerade derivat av mitomucin c

Info

Publication number: SE8504659L
Authority: SE; Sweden
Prior art keywords: methoxymitosane; amino; mitomucin; preparing; procedure
Prior art date: 1984-10-09

Application number

SE8504659A

Other languages

English (en)

Swedish (sv)

Other versions

SE8504659D0 (sv

Inventor

H S L Wong

T Kaneko

T W Doyle

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-09

Filing date

1985-10-08

Publication date

1986-04-10

1985-10-08 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1985-10-08 Publication of SE8504659D0 publication Critical patent/SE8504659D0/xx

1986-04-10 Publication of SE8504659L publication Critical patent/SE8504659L/xx

Links

NWIBSHFKIJFRCO-WUDYKRTCSA-N Mytomycin Chemical class C1N2C(C(C(C)=C(N)C3=O)=O)=C3[C@@H](COC(N)=O)[C@@]2(OC)[C@@H]2[C@H]1N2 NWIBSHFKIJFRCO-WUDYKRTCSA-N 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
HRHKSTOGXBBQCB-UHFFFAOYSA-N Mitomycin E Natural products O=C1C(N)=C(C)C(=O)C2=C1C(COC(N)=O)C1(OC)C3N(C)C3CN12 HRHKSTOGXBBQCB-UHFFFAOYSA-N 0.000 abstract 1
125000000129 anionic group Chemical group 0.000 abstract 1
150000001450 anions Chemical class 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
239000012039 electrophile Substances 0.000 abstract 1
HRHKSTOGXBBQCB-VFWICMBZSA-N methylmitomycin Chemical compound O=C1C(N)=C(C)C(=O)C2=C1[C@@H](COC(N)=O)[C@@]1(OC)[C@H]3N(C)[C@H]3CN12 HRHKSTOGXBBQCB-VFWICMBZSA-N 0.000 abstract 1
229960004857 mitomycin Drugs 0.000 abstract 1
230000000269 nucleophilic effect Effects 0.000 abstract 1
229950004406 porfiromycin Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SE8504659A 1984-10-09 1985-10-08 Forfarande for framstellning av n?72-substituerade derivat av mitomucin c SE8504659L (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US65912884A	1984-10-09	1984-10-09

Publications (2)

Publication Number	Publication Date
SE8504659D0 SE8504659D0 (sv)	1985-10-08
SE8504659L true SE8504659L (sv)	1986-04-10

Family

ID=24644154

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8504659A SE8504659L (sv)	1984-10-09	1985-10-08	Forfarande for framstellning av n?72-substituerade derivat av mitomucin c

Country Status (7)

Country	Link
JP (1)	JPS6191189A (da)
DK (1)	DK460285A (da)
FR (1)	FR2571373A1 (da)
GB (1)	GB2165249A (da)
HU (1)	HUT38943A (da)
IT (1)	IT1187749B (da)
SE (1)	SE8504659L (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6354380A (ja) *	1986-08-26	1988-03-08	Kyowa Hakko Kogyo Co Ltd	マイトマイシン誘導体
EP0284380B1 (en) *	1987-03-25	1992-06-10	Kyowa Hakko Kogyo Kabushiki Kaisha	Mitomycin derivatives
IL86665A0 (en) *	1987-06-12	1988-11-30	Bristol Myers Co	Mitomycin analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ199617A (en) *	1981-05-15	1985-08-30	University Patents Inc	Azirino(2',3',:3,4)pyrrolo(1,2-a)indole-4,7-dione derivatives and pharmaceutical compositions
US4642352A (en) *	1983-12-23	1987-02-10	Bristol-Myers Company	Acylamino mitosanes

1985
- 1985-09-03 FR FR8513072A patent/FR2571373A1/fr active Pending
- 1985-10-08 JP JP60224631A patent/JPS6191189A/ja active Pending
- 1985-10-08 IT IT8522385A patent/IT1187749B/it active
- 1985-10-08 SE SE8504659A patent/SE8504659L/xx not_active Application Discontinuation
- 1985-10-08 DK DK460285A patent/DK460285A/da not_active Application Discontinuation
- 1985-10-08 GB GB08524725A patent/GB2165249A/en not_active Withdrawn
- 1985-10-08 HU HU853906A patent/HUT38943A/hu unknown

Also Published As

Publication number	Publication date
DK460285A (da)	1986-04-10
SE8504659D0 (sv)	1985-10-08
IT8522385A0 (it)	1985-10-08
DK460285D0 (da)	1985-10-08
JPS6191189A (ja)	1986-05-09
HUT38943A (en)	1986-07-28
GB2165249A (en)	1986-04-09
IT1187749B (it)	1987-12-23
GB8524725D0 (en)	1985-11-13
FR2571373A1 (fr)	1986-04-11

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Legal Events

Date

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Title

Description

1995-02-28

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