SE8505887L - Indoler - Google Patents

Indoler

Info

Publication number: SE8505887L
Authority: SE; Sweden
Prior art keywords: alkyl; represents hydrogen; phenyl; group; r7r8n
Prior art date: 1984-12-13

Application number

SE8505887A

Other languages

English (en)

Swedish (sv)

Other versions

SE8505887D0 (sv

Inventor

D E Bays

C F Webb

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-12-13

Filing date

1985-12-12

Publication date

1986-06-14

1985-12-12 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1985-12-12 Publication of SE8505887D0 publication Critical patent/SE8505887D0/xx

1986-06-14 Publication of SE8505887L publication Critical patent/SE8505887L/xx

Links

150000002475 indoles Chemical class 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 5
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
150000002431 hydrogen Chemical group 0.000 abstract 2
125000002950 monocyclic group Chemical group 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
208000019695 Migraine disease Diseases 0.000 abstract 1
208000002193 Pain Diseases 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
206010027599 migraine Diseases 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
125000003884 phenylalkyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
210000005166 vasculature Anatomy 0.000 abstract 1
239000005526 vasoconstrictor agent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)

SE8505887A 1984-12-13 1985-12-12 Indoler SE8505887L (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB848431426A GB8431426D0 (en)	1984-12-13	1984-12-13	Chemical compounds

Publications (2)

Publication Number	Publication Date
SE8505887D0 SE8505887D0 (sv)	1985-12-12
SE8505887L true SE8505887L (sv)	1986-06-14

Family

ID=10571103

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8505887A SE8505887L (sv)	1984-12-13	1985-12-12	Indoler

Country Status (11)

Country	Link
JP (1)	JPS61151172A (fr)
AU (1)	AU579687B2 (fr)
BE (1)	BE903846A (fr)
CH (1)	CH667454A5 (fr)
DE (1)	DE3543982A1 (fr)
FR (1)	FR2574793B1 (fr)
GB (2)	GB8431426D0 (fr)
IT (1)	IT1182089B (fr)
NL (1)	NL8503424A (fr)
SE (1)	SE8505887L (fr)
ZA (1)	ZA859520B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8530507D0 (en) *	1985-12-11	1986-01-22	Glaxo Group Plc	Chemical compounds
GB8607824D0 (en) *	1986-03-27	1986-04-30	Glaxo Group Ltd	Chemical compounds
GB8614287D0 (en) *	1986-06-12	1986-07-16	Glaxo Group Ltd	Chemical compounds
US4894386A (en) *	1987-04-15	1990-01-16	Ici Americas Inc.	Aliphatic carboxamides
GB8719167D0 (en) *	1987-08-13	1987-09-23	Glaxo Group Ltd	Chemical compounds
US5225431A (en) *	1987-10-23	1993-07-06	Burroughs Wellcome Co.	Therapeutic substituted indole compounds and compositions thereof
PT97888B (pt) *	1990-06-07	1998-12-31	Zeneca Ltd	Processo para a preparacao de compostos heterociclicos derivados de indol e de composicoes farmaceuticas que os contem
GB9209882D0 (en) *	1992-05-07	1992-06-24	Glaxo Lab Sa	Compositions
GB9211277D0 (en)	1992-05-28	1992-07-15	Glaxo Group Inc	Pharmaceutical compositions
GB9216009D0 (en) *	1992-07-28	1992-09-09	Almirall Lab	New indol derivatives
ES2056025B1 (es) *	1992-10-08	1995-05-01	Almirall Lab	Nuevos derivados de indol.
FR2707639B1 (fr) *	1993-06-30	1995-10-13	Pf Medicament	Nouveaux composés indoliques dérivés d'arylamines comme ligands sélectifs des récepteurs 5HT1D et 5HT1B.
US7189753B1 (en)	1997-11-06	2007-03-13	Cady Roger K	Preemptive prophylaxis of migraine
EP1572647B1 (fr)	2002-12-20	2016-09-21	Basf Se	Préparation d´amines et de leurs intermédiaires
WO2005118551A2 (fr)	2004-05-28	2005-12-15	Ligand Pharmaceuticals Inc.	Composes modulant l'activite de la thrombopoietine et methodes associees
JP4728340B2 (ja)	2004-10-25	2011-07-20	リガンド・ファーマシューティカルズ・インコーポレイテッド	トロンボポエチン活性を変調する化合物および変調方法
CN101679248A (zh)	2007-03-29	2010-03-24	阿斯比奥制药株式会社	具有cPLA2抑制活性的吲哚衍生物及其用途以及制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA795239B (en) *	1978-10-12	1980-11-26	Glaxo Group Ltd	Heterocyclic compounds
GB2082175B (en) *	1980-08-12	1984-05-02	Glaxo Group Ltd	Heterocyclic compounds
IT1181741B (it) *	1984-12-04	1987-09-30	Glaxo Group Ltd	Derivati di indolo,procedimento per prepararli e composizioni farmaceutiche che li contengono
GB8530507D0 (en) *	1985-12-11	1986-01-22	Glaxo Group Plc	Chemical compounds

1984
- 1984-12-13 GB GB848431426A patent/GB8431426D0/en active Pending
1985
- 1985-12-12 NL NL8503424A patent/NL8503424A/nl not_active Application Discontinuation
- 1985-12-12 SE SE8505887A patent/SE8505887L/xx not_active Application Discontinuation
- 1985-12-12 JP JP60278124A patent/JPS61151172A/ja active Pending
- 1985-12-12 IT IT48921/85A patent/IT1182089B/it active
- 1985-12-12 DE DE19853543982 patent/DE3543982A1/de not_active Withdrawn
- 1985-12-12 GB GB08530591A patent/GB2168347B/en not_active Expired
- 1985-12-12 CH CH5301/85A patent/CH667454A5/fr not_active IP Right Cessation
- 1985-12-12 ZA ZA859520A patent/ZA859520B/xx unknown
- 1985-12-12 BE BE0/216004A patent/BE903846A/fr not_active IP Right Cessation
- 1985-12-12 FR FR8518416A patent/FR2574793B1/fr not_active Expired
- 1985-12-12 AU AU51151/85A patent/AU579687B2/en not_active Ceased

Also Published As

Publication number	Publication date
GB8530591D0 (en)	1986-01-22
JPS61151172A (ja)	1986-07-09
DE3543982A1 (de)	1986-06-19
BE903846A (fr)	1986-06-12
GB8431426D0 (en)	1985-01-23
NL8503424A (nl)	1986-07-01
FR2574793B1 (fr)	1988-10-14
SE8505887D0 (sv)	1985-12-12
IT8548921A0 (it)	1985-12-12
GB2168347A (en)	1986-06-18
FR2574793A1 (fr)	1986-06-20
CH667454A5 (fr)	1988-10-14
GB2168347B (en)	1988-02-03
IT1182089B (it)	1987-09-30
AU579687B2 (en)	1988-12-01
AU5115185A (en)	1986-06-19
ZA859520B (en)	1986-08-27

Legal Events

Date

Code

Title

Description

1995-02-28

NAV

Patent application has lapsed

Ref document number: 8505887-3

Effective date: 19901109

Format of ref document f/p: F

Publication	Publication Date	Title
SE8505887L (sv)	1986-06-14	Indoler
SE8503680D0 (sv)	1985-08-01	Indolderivat
ES8707223A1 (es)	1987-07-16	Un procedimiento para la preparacion de derivados de benzotiazol y benzotiofen.
ES8700660A1 (es)	1986-10-16	Un procedimiento para la preparacion de derivados de bencimidasol.
SE8505715L (sv)	1986-06-05	Indolderivat
DE3462504D1 (de)	1987-04-09	Indole-3-carboxamide derivatives
ES433902A1 (es)	1976-11-16	Procedimiento para la preparacion de bencilaminas.
SE8104783L (sv)	1982-02-13	Heterocykliska foreningar
NO171059C (no)	1993-01-20	Analogifremgangsmaate for fremstilling av terapeutisk aktive, disubstituerte benzylaminer
ES551988A0 (es)	1987-07-01	Procedimiento para preparar un derivado de cefalosporina.
MY113427A (en)	2002-02-28	Anti-neurodegeneratively active 10-aminoaliphatyl- dibenz [b,f] oxepines
ES431020A1 (es)	1977-01-16	Procedimiento para la preparacion de derivados de 1,4-dihi- dro-2h-isoquinoleina.
ES2038127T3 (es)	1993-07-16	Procedimiento para preparar monosulfactamas.
ATE70274T1 (de)	1991-12-15	Substituierte 1,8-naphthyridin-derivate und diese enthaltende fungizide.
GB2108495B (en)	1985-07-24	Triazoloquinazolone derivatives
ES467069A1 (es)	1979-10-16	Un procedimiento para la preparacion de nuevos derivados de 1-3-bencenodimetanol
ES8502977A1 (es)	1985-02-01	Un metodo de preparar profarmacos de pilocarpina
ES2054186T3 (es)	1994-08-01	Composicion antihepatopatica.
NO870423L (no)	1987-08-05	5-substituerte oktahydroindolizin-analgetiske forbindelser og 7-keto mellomprodukter.
DK7286A (da)	1986-07-10	Octahydroindoliziner
ES543802A0 (es)	1986-01-16	Procedimiento de preparacion de nuevos derivados a-etilben- zol con un grupo n-carbamiloxi sustituido
FI865234A0 (fi)	1986-12-19	5-aminoalkyl- -karbolinderivat, deras framstaellning och anvaendning som laekemedel.
DK52383D0 (da)	1983-02-08	Fremgangsmade til fremstilling af carbacyklinderivater
MY103577A (en)	1993-08-28	New aminoacylates of glycerol acetal
ES8707500A1 (es)	1987-08-16	Procedimiento para la obtencion de isocianatos piperidinicos.