ES2038127T3 - Procedimiento para preparar monosulfactamas. - Google Patents

Procedimiento para preparar monosulfactamas.

Info

Publication number
ES2038127T3
ES2038127T3 ES198787100056T ES87100056T ES2038127T3 ES 2038127 T3 ES2038127 T3 ES 2038127T3 ES 198787100056 T ES198787100056 T ES 198787100056T ES 87100056 T ES87100056 T ES 87100056T ES 2038127 T3 ES2038127 T3 ES 2038127T3
Authority
ES
Spain
Prior art keywords
monosulfactams
preparing
procedure
group
acilamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787100056T
Other languages
English (en)
Inventor
Joseph Edward Sundeen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Application granted granted Critical
Publication of ES2038127T3 publication Critical patent/ES2038127T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE MUESTRA LA ACTIVIDAD ANTIBACTERIANA DE LOS ANTIBIOTICOS DE BETA-LACTAMA MONOCICLICOS QUE TIENEN EN LA POSICION 1 UN GRUPO ACTIVADOR -O-SO3H Y EN LA POSICION 3 UN GRUPO ACILAMINO DE LA FORMULA (I) EN LA QUE R3 Y R4 SON, CADA UNO DE ELLOS INDEPENDIENTEMENTE, HIDROGENO O ALQUILO.
ES198787100056T 1986-01-06 1987-01-05 Procedimiento para preparar monosulfactamas. Expired - Lifetime ES2038127T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/816,475 US4684722A (en) 1986-01-06 1986-01-06 Monosulfactams

Publications (1)

Publication Number Publication Date
ES2038127T3 true ES2038127T3 (es) 1993-07-16

Family

ID=25220721

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787100056T Expired - Lifetime ES2038127T3 (es) 1986-01-06 1987-01-05 Procedimiento para preparar monosulfactamas.

Country Status (21)

Country Link
US (1) US4684722A (es)
EP (1) EP0229012B1 (es)
JP (1) JPS62158278A (es)
KR (1) KR900002244B1 (es)
AT (1) ATE64393T1 (es)
AU (3) AU602133B2 (es)
CA (1) CA1308107C (es)
DD (3) DD256700A5 (es)
DE (1) DE3770644D1 (es)
DK (1) DK3087A (es)
ES (1) ES2038127T3 (es)
FI (1) FI870030A7 (es)
GR (1) GR3002312T3 (es)
HU (2) HU198700B (es)
IL (1) IL81153A (es)
NO (1) NO166860C (es)
NZ (1) NZ218682A (es)
PH (1) PH23052A (es)
SU (1) SU1517762A3 (es)
YU (2) YU227886A (es)
ZA (1) ZA8771B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6452767A (en) * 1986-03-19 1989-02-28 Banyu Pharma Co Ltd 2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-vinyloxyimino)acetic acid derivative and production thereof
JPS6393796A (ja) * 1986-10-09 1988-04-25 Shin Etsu Chem Co Ltd ペプチド合成の脱保護基用薬剤
US5143913A (en) * 1988-04-04 1992-09-01 E. R. Squibb & Sons, Inc. [3S(Z)]-3-[[(2-amino-4-thiazolyl)[[2-(hydroxyamino)-2-oxoethoxy]imino]acetyl]amino]-2,2-dimethyl-4-oxo-1-azetidinyl sulfate
JPH07165740A (ja) * 1994-11-07 1995-06-27 Banyu Pharmaceut Co Ltd ２−（２−アミノチアゾリル）−２−（１−カルボキシ−１−ビニルオキシイミノ）酢酸及びその製法
EP0880511A4 (en) * 1996-01-16 1999-06-16 Merck & Co Inc Integrin receptor antagonists
US5952306A (en) * 1996-01-16 1999-09-14 Merck & Co., Inc. Integrin receptor antagonists
US9120796B2 (en) 2013-10-02 2015-09-01 Cubist Pharmaceuticals, Inc. B-lactamase inhibitor picoline salt
AU2016371600B2 (en) 2015-12-15 2021-02-18 Merck Sharp & Dohme Llc Biaryl monobactam compounds and methods of use thereof for the treatment of bacterial infections
US10407421B2 (en) 2016-03-07 2019-09-10 Merck Sharp & Dohme Corp Bicyclic aryl monobactam compounds and methods of use thereof for the treatment of bacterial infections
US10002721B1 (en) * 2017-02-27 2018-06-19 Carling Technologies, Inc. Multiple contact circuit breaker
GEAP202215303A (en) 2017-10-02 2022-04-11 Merck Sharp & Dohme Chromane monobactam compounds for the treatment of bacterial infections
CN113754651B (zh) 2020-06-02 2023-04-18 中国医学科学院医药生物技术研究所 一种β-内酰胺化合物、其用途及其制备方法
CN118255695B (zh) * 2024-02-26 2025-03-14 广州艾奇西医药科技有限公司 一种β-内酰胺类化合物的中间体的纯化方法和制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU526540B2 (en) * 1976-04-12 1983-01-20 Fujisawa Pharmaceutical Co., Ltd. Oximes of substituted phenyl, thiazolyl - glyoxylic acids
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
GB1602725A (en) * 1977-04-27 1981-11-18 Glaxo Operations Ltd 7-(a-oxyiminoacetamido)-ceph-3-em-4-carboxylic acid derivatives
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4533660A (en) * 1980-10-31 1985-08-06 E. R. Squibb & Sons, Inc. Antibacterial O-sulfated β-lactam hydroxamic acids
JPS58113174A (ja) * 1981-12-26 1983-07-05 Toyama Chem Co Ltd 新規なアゼチジン誘導体またはその塩類を含有する抗菌剤
US4443374A (en) * 1982-02-01 1984-04-17 E. R. Squibb & Sons, Inc. Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives
AU564150B2 (en) * 1982-04-30 1987-08-06 Takeda Chemical Industries Ltd. 1-sulfo-2-azetidinone derivatives
JPS58206589A (ja) * 1982-05-26 1983-12-01 Yamanouchi Pharmaceut Co Ltd ２−アゼチジノン誘導体
HU189290B (en) * 1982-05-31 1986-06-30 Banyu Pharmaceutical Co Ltd,Jp Process for preparing new 2-oxo-1-azetidine-sulphonic acid derivatives and pharmaceutically acceptable salts thereof, further pharmaceutical compositions containing such derivatives as active substances
JPS58210060A (ja) * 1982-05-31 1983-12-07 Takeda Chem Ind Ltd ２−オキソアゼチジン誘導体、その製造法および用途
EP0096296B1 (de) * 1982-06-03 1987-07-29 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft 1-Sulfo-2-oxoazetidinderivate
DE3377061D1 (en) * 1982-06-03 1988-07-21 Hoffmann La Roche Process for the preparation of 1-sulfo-2-oxoazetidine derivatives
US4704457A (en) * 1982-06-21 1987-11-03 E. R. Squibb & Sons, Inc. Process for the preparation of (3S)-3-[[[2-(protected amino)-4-thiazolyl]-oxoacetyl]amino]-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives thereof
GB8413152D0 (en) * 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
DE3342929A1 (de) * 1983-11-26 1985-06-05 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
KR870007164A (ko) 1987-08-17
US4684722A (en) 1987-08-04
IL81153A (en) 1991-06-10
ATE64393T1 (de) 1991-06-15
PH23052A (en) 1989-03-10
AU5885190A (en) 1990-10-25
DK3087D0 (da) 1987-01-05
HUT44540A (en) 1988-03-28
CA1308107C (en) 1992-09-29
AU5885090A (en) 1990-11-15
HU198700B (en) 1989-11-28
GR3002312T3 (en) 1992-12-30
YU127887A (en) 1988-04-30
DD267035A5 (de) 1989-04-19
DD256700A5 (de) 1988-05-18
DD267039A5 (de) 1989-04-19
FI870030L (fi) 1987-07-07
NO870031D0 (no) 1987-01-05
ZA8771B (en) 1987-08-26
NO166860C (no) 1991-09-11
AU602133B2 (en) 1990-10-04
JPS62158278A (ja) 1987-07-14
SU1517762A3 (ru) 1989-10-23
FI870030A0 (fi) 1987-01-05
NO166860B (no) 1991-06-03
HU198926B (en) 1989-12-28
IL81153A0 (en) 1987-08-31
EP0229012A1 (en) 1987-07-15
KR900002244B1 (ko) 1990-04-07
NZ218682A (en) 1990-05-28
NO870031L (no) 1987-07-07
AU6680886A (en) 1987-07-09
DK3087A (da) 1987-07-07
EP0229012B1 (en) 1991-06-12
DE3770644D1 (de) 1991-07-18
AU617059B2 (en) 1991-11-14
FI870030A7 (fi) 1987-07-07
HUT48876A (en) 1989-07-28
YU227886A (en) 1988-02-29

Similar Documents

Publication Publication Date Title
ES2040261T3 (es) Procedimiento para preparar acidos 6-fluor-4-oxo-1,4-dihidroquinolina-3-carboxilicos sustituidos y acidos 9-fluor-3-metil-7-oxo-2,3-dihidro-7h-pirido(1,2,3-de)(1,4)benzoxazina-6-carboxilico sustituidos.
ES2112913T3 (es) N-fenilpirazoles utiles como insecticidas y acaricidas.
ES2066808T3 (es) Derivados de quinoleina, su produccion y uso.
NO931635L (no) Fremgangsmaate for fremstilling av kinazolin-derivater
ES2080739T3 (es) Nitro-compuestos insecticidamente activos.
ES2040838T3 (es) Compuestos piperazinil-heterociclicos.
YU211087A (en) Process for obtaining new n-substituted benzimidazolic derivatives
NO900279D0 (no) Alkylerte polyetyleniminderivater og fremgangsmaate for fremstilling derav samt anvendelse av derivatene.
DE3774918D1 (de) Cancerostatisches mittel.
SE8602404L (sv) Ny formulering
FI865233A0 (fi) Pyrazolinderivat, deras framstaellning och anvaendning som medel med insekticid och akaricid verkan.
AR246509A1 (es) Una cetimina, su preparacion y un agente de entrecruzamiento que la contiene.
NO964236D0 (no) Anvendelse av serotonin-antagonister (5HT3) for behandling av fibromyalgi
ES2009785B3 (es) Procedimiento para preparar derivados de tioxantona.
ES2095068T3 (es) Peroxicarbonatos polimericos y procedimiento para prepararlos.
ES2037418T3 (es) Agentes diureticos de glutaramida enantiomerica.
ES2054186T3 (es) Composicion antihepatopatica.
ES2059374T3 (es) Substancia 4181-2 y sus derivados.
ES2101738T3 (es) Tintes de benzoxacina.
NO872875L (no) Modifisert vevsplasminaktivator, samt fremgangsmŸte for fremstilling av en slik.
ES8704469A1 (es) Procedimiento para preparar naftoxacinas
MY102026A (en) Antiasthmatic.
ES2043778T3 (es) Procedimiento para preparar oxiindanos y tetrahidronaftalenos herbicidas.
DK0457215T3 (da) 3-deamino-4-desoxy-4-amino-8-fluoranthracycliner samt fremgangsmåder til fremstilling deraf
ES8801624A1 (es) Procedimiento para preparar disulfuros heterociclicos

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 229012

Country of ref document: ES