SE9300937L - Komposition för oral administrering av peptider - Google Patents
Komposition för oral administrering av peptiderInfo
- Publication number
- SE9300937L SE9300937L SE9300937A SE9300937A SE9300937L SE 9300937 L SE9300937 L SE 9300937L SE 9300937 A SE9300937 A SE 9300937A SE 9300937 A SE9300937 A SE 9300937A SE 9300937 L SE9300937 L SE 9300937L
- Authority
- SE
- Sweden
- Prior art keywords
- pct
- oral administration
- spheres
- date sep
- sec
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 102400000050 Oxytocin Human genes 0.000 abstract 1
- 101800000989 Oxytocin Proteins 0.000 abstract 1
- XNOPRXBHLZRZKH-UHFFFAOYSA-N Oxytocin Natural products N1C(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CC(C)C)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(C(C)CC)NC(=O)C1CC1=CC=C(O)C=C1 XNOPRXBHLZRZKH-UHFFFAOYSA-N 0.000 abstract 1
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 abstract 1
- GXBMIBRIOWHPDT-UHFFFAOYSA-N Vasopressin Natural products N1C(=O)C(CC=2C=C(O)C=CC=2)NC(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CCCN=C(N)N)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C1CC1=CC=CC=C1 GXBMIBRIOWHPDT-UHFFFAOYSA-N 0.000 abstract 1
- 108010004977 Vasopressins Proteins 0.000 abstract 1
- 102000002852 Vasopressins Human genes 0.000 abstract 1
- KBZOIRJILGZLEJ-LGYYRGKSSA-N argipressin Chemical compound C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 KBZOIRJILGZLEJ-LGYYRGKSSA-N 0.000 abstract 1
- 239000006172 buffering agent Substances 0.000 abstract 1
- 230000003139 buffering effect Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- XNOPRXBHLZRZKH-DSZYJQQASA-N oxytocin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@H](N)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 XNOPRXBHLZRZKH-DSZYJQQASA-N 0.000 abstract 1
- 229960001723 oxytocin Drugs 0.000 abstract 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 229960003726 vasopressin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9300937A SE9300937L (sv) | 1993-03-19 | 1993-03-19 | Komposition för oral administrering av peptider |
| DK94911346T DK0689452T3 (da) | 1993-03-19 | 1994-03-18 | Sammensætning til oral administration af peptider |
| AT94911346T ATE181508T1 (de) | 1993-03-19 | 1994-03-18 | Zusammensetzungen zur oralen verabreichung von peptiden |
| ES94911346T ES2135570T3 (es) | 1993-03-19 | 1994-03-18 | Composicion para la administracion oral de peptidos. |
| EP94911346A EP0689452B1 (en) | 1993-03-19 | 1994-03-18 | Composition for oral administration of peptides |
| US08/525,584 US5780434A (en) | 1993-03-19 | 1994-03-18 | Composition for oral administration of peptides |
| DE69419246T DE69419246T2 (de) | 1993-03-19 | 1994-03-18 | Zusammensetzungen zur oralen verabreichung von peptiden |
| AU63889/94A AU6388994A (en) | 1993-03-19 | 1994-03-18 | Composition for oral administration of peptides |
| PCT/SE1994/000244 WO1994021286A1 (en) | 1993-03-19 | 1994-03-18 | Composition for oral administration of peptides |
| GR990402412T GR3031312T3 (en) | 1993-03-19 | 1999-09-22 | Composition for oral administration of peptides |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9300937A SE9300937L (sv) | 1993-03-19 | 1993-03-19 | Komposition för oral administrering av peptider |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE9300937D0 SE9300937D0 (sv) | 1993-03-19 |
| SE9300937L true SE9300937L (sv) | 1994-09-20 |
Family
ID=20389308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9300937A SE9300937L (sv) | 1993-03-19 | 1993-03-19 | Komposition för oral administrering av peptider |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5780434A (sv) |
| EP (1) | EP0689452B1 (sv) |
| AT (1) | ATE181508T1 (sv) |
| AU (1) | AU6388994A (sv) |
| DE (1) | DE69419246T2 (sv) |
| DK (1) | DK0689452T3 (sv) |
| ES (1) | ES2135570T3 (sv) |
| GR (1) | GR3031312T3 (sv) |
| SE (1) | SE9300937L (sv) |
| WO (1) | WO1994021286A1 (sv) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9325445D0 (en) | 1993-12-13 | 1994-02-16 | Cortecs Ltd | Pharmaceutical formulations |
| SE9400918L (sv) * | 1994-03-18 | 1995-09-19 | Anne Fjellstad Paulsen | Stabiliserad komposition för oral administrering av peptider |
| US8765177B2 (en) * | 1997-09-12 | 2014-07-01 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| US7153845B2 (en) * | 1998-08-25 | 2006-12-26 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| JP4344136B2 (ja) | 2000-11-10 | 2009-10-14 | エフ・ホフマン−ラ・ロシュ・リミテッド | アポリポタンパク質類似体 |
| GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
| ES2260563T3 (es) * | 2003-11-13 | 2006-11-01 | Ferring B.V. | Paquete de blister y forma farmaceutica solida para ello. |
| KR20070109985A (ko) | 2004-11-22 | 2007-11-15 | 아나디스 리미티드 | 생물활성 조성물 |
| WO2007025286A2 (en) * | 2005-08-26 | 2007-03-01 | The Board Of Trustees Of The Leland Stanford Junior University | Therapy procedure for drug delivery for trigeminal pain |
| SE528446C2 (sv) * | 2006-03-02 | 2006-11-14 | Ferring Int Ct Sa | Farmaceutisk sammansättning innefattande desmopressin, kiseldioxid och stärkelse |
| US20080260820A1 (en) * | 2007-04-19 | 2008-10-23 | Gilles Borrelly | Oral dosage formulations of protease-resistant polypeptides |
| ES2319054B1 (es) | 2007-08-06 | 2010-02-12 | Gp Pharm S.A. | Composicion farmaceutica oral de desmopresina. |
| KR20140143461A (ko) | 2007-08-06 | 2014-12-16 | 알레간 인코포레이티드 | 데스모프레신 약물 전달을 위한 방법 및 장치 |
| SI2712622T1 (sl) * | 2008-05-21 | 2016-10-28 | Ferring B.V. | Orodisperzibilni dezmopresin za povečanje začetnega obdobja spanja nemotenega z nokturijo |
| US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
| US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
| PT2442821T (pt) | 2009-06-18 | 2017-09-29 | Allergan Inc | Administração segura de desmopressina |
| US11389473B2 (en) | 2015-01-07 | 2022-07-19 | Tonix Pharmaceuticals Holding Corp. | Magnesium-containing oxytocin formulations and methods of use |
| MX2018012351A (es) | 2016-04-12 | 2019-02-07 | Trigemina Inc | Formulaciones de oxitocina que contienen magnesio y metodos de uso. |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4139504A (en) * | 1977-06-16 | 1979-02-13 | Coy David Howard | Novel nonapeptides, intermediates therefor, and compositions and methods employing said nonapeptides |
| IL68769A (en) * | 1983-05-23 | 1986-02-28 | Hadassah Med Org | Pharmaceutical compositions containing insulin for oral administration |
| JPS608225A (ja) * | 1983-06-29 | 1985-01-17 | Kowa Co | 腸管吸収医薬組成物 |
| SE8306367L (sv) * | 1983-11-18 | 1985-05-19 | Ferring Ab | Antidiuretiskt verkande farmaceutiskt preparat |
| US4849227A (en) * | 1986-03-21 | 1989-07-18 | Eurasiam Laboratories, Inc. | Pharmaceutical compositions |
| WO1989007110A1 (en) * | 1988-01-28 | 1989-08-10 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
| DE3919982A1 (de) * | 1989-06-19 | 1990-12-20 | Liedtke Pharmed Gmbh | Orale lipidarzneiform |
| JP3009911B2 (ja) * | 1989-06-28 | 2000-02-14 | エーザイ株式会社 | ペプチド又は蛋白の内服用新規製剤 |
| JPH04364131A (ja) * | 1991-04-03 | 1992-12-16 | Sanwa Kagaku Kenkyusho Co Ltd | 易吸収性モチリン製剤 |
| US5206219A (en) * | 1991-11-25 | 1993-04-27 | Applied Analytical Industries, Inc. | Oral compositions of proteinaceous medicaments |
-
1993
- 1993-03-19 SE SE9300937A patent/SE9300937L/sv not_active Application Discontinuation
-
1994
- 1994-03-18 AT AT94911346T patent/ATE181508T1/de not_active IP Right Cessation
- 1994-03-18 ES ES94911346T patent/ES2135570T3/es not_active Expired - Lifetime
- 1994-03-18 DK DK94911346T patent/DK0689452T3/da active
- 1994-03-18 US US08/525,584 patent/US5780434A/en not_active Expired - Fee Related
- 1994-03-18 AU AU63889/94A patent/AU6388994A/en not_active Abandoned
- 1994-03-18 WO PCT/SE1994/000244 patent/WO1994021286A1/en not_active Ceased
- 1994-03-18 EP EP94911346A patent/EP0689452B1/en not_active Expired - Lifetime
- 1994-03-18 DE DE69419246T patent/DE69419246T2/de not_active Expired - Fee Related
-
1999
- 1999-09-22 GR GR990402412T patent/GR3031312T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE9300937D0 (sv) | 1993-03-19 |
| GR3031312T3 (en) | 1999-12-31 |
| WO1994021286A1 (en) | 1994-09-29 |
| DE69419246T2 (de) | 2000-01-20 |
| EP0689452A1 (en) | 1996-01-03 |
| US5780434A (en) | 1998-07-14 |
| AU6388994A (en) | 1994-10-11 |
| DK0689452T3 (da) | 1999-12-13 |
| DE69419246D1 (de) | 1999-07-29 |
| EP0689452B1 (en) | 1999-06-23 |
| ES2135570T3 (es) | 1999-11-01 |
| ATE181508T1 (de) | 1999-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 9300937-1 |