SE9303323L - Förfarande för framställning av kristallint botulinumtoxin typ a som terapeutisk medicin - Google Patents
Förfarande för framställning av kristallint botulinumtoxin typ a som terapeutisk medicinInfo
- Publication number
- SE9303323L SE9303323L SE9303323A SE9303323A SE9303323L SE 9303323 L SE9303323 L SE 9303323L SE 9303323 A SE9303323 A SE 9303323A SE 9303323 A SE9303323 A SE 9303323A SE 9303323 L SE9303323 L SE 9303323L
- Authority
- SE
- Sweden
- Prior art keywords
- preparation
- toxin
- botulinum toxin
- therapeutic medicine
- toxin type
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 108010057266 Type A Botulinum Toxins Proteins 0.000 title 1
- 229940094657 botulinum toxin type a Drugs 0.000 title 1
- 239000003053 toxin Substances 0.000 abstract 3
- 231100000765 toxin Toxicity 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 108030001720 Bontoxilysin Proteins 0.000 abstract 1
- 208000004350 Strabismus Diseases 0.000 abstract 1
- 206010005159 blepharospasm Diseases 0.000 abstract 1
- 230000000744 blepharospasm Effects 0.000 abstract 1
- 229940053031 botulinum toxin Drugs 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000009849 deactivation Effects 0.000 abstract 1
- 238000004925 denaturation Methods 0.000 abstract 1
- 230000036425 denaturation Effects 0.000 abstract 1
- 239000005445 natural material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4311158A JPH06192296A (ja) | 1992-10-28 | 1992-10-28 | 治療用医薬品としての結晶a型ボツリヌス毒素の製造法。 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE9303323D0 SE9303323D0 (sv) | 1993-10-11 |
| SE9303323L true SE9303323L (sv) | 1994-04-29 |
Family
ID=18013801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9303323A SE9303323L (sv) | 1992-10-28 | 1993-10-11 | Förfarande för framställning av kristallint botulinumtoxin typ a som terapeutisk medicin |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPH06192296A (da) |
| DE (1) | DE4335366A1 (da) |
| DK (1) | DK112793A (da) |
| FR (1) | FR2697163B1 (da) |
| GB (1) | GB2272697A (da) |
| SE (1) | SE9303323L (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5919665A (en) | 1989-10-31 | 1999-07-06 | Ophidian Pharmaceuticals, Inc. | Vaccine for clostridium botulinum neurotoxin |
| GB9120306D0 (en) | 1991-09-24 | 1991-11-06 | Graham Herbert K | Method and compositions for the treatment of cerebral palsy |
| US8187612B2 (en) | 1993-12-28 | 2012-05-29 | Allergan, Inc. | Use of the neurotoxic component of a botulinum toxin for treating a spastic muscle |
| US6974578B1 (en) | 1993-12-28 | 2005-12-13 | Allergan, Inc. | Method for treating secretions and glands using botulinum toxin |
| US8557256B2 (en) | 1993-12-28 | 2013-10-15 | Allergan, Inc. | Treatment for cervical dystonia with the neurotoxic component of a botulinum toxin |
| AU709586B2 (en) * | 1994-10-24 | 1999-09-02 | Ophidian Pharmaceuticals, Inc. | Vaccine and antitoxin for treatment and prevention of C. difficile disease |
| JP2003009897A (ja) | 2001-07-03 | 2003-01-14 | Keiji Oguma | ボツリヌス毒素の分離・精製法 |
| RU2257914C1 (ru) * | 2004-03-31 | 2005-08-10 | Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" им. акад. С.Н. Федорова Министерства Здравоохранения Российской Федерации | Способ лечения паралитического косоглазия |
| CN102614264A (zh) * | 2012-05-02 | 2012-08-01 | 马守云 | 一种治疗眼脸痉挛的药物 |
| RU2535115C1 (ru) * | 2013-05-15 | 2014-12-10 | Бости Трейдинг Лтд | Фармацевтический состав, содержащий нейротоксин ботулина |
| KR101775682B1 (ko) | 2015-11-30 | 2017-09-06 | 주식회사 대웅 | 보툴리눔 독소의 제조방법 |
| WO2024191217A1 (ko) | 2023-03-16 | 2024-09-19 | 주식회사 대웅 | 다중모드 크로마토그래피를 이용한 개선된 보툴리눔 독소의 정제방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR940005589B1 (ko) * | 1986-04-02 | 1994-06-21 | 다이닛뽄세이야꾸 가부시끼가이샤 | 핵산 또는 엔도톡신의 제거제 및 제거방법 |
| US5053005A (en) * | 1989-04-21 | 1991-10-01 | Gary E. Borodic | Chemomodulation of curvature of the juvenile spine |
-
1992
- 1992-10-28 JP JP4311158A patent/JPH06192296A/ja active Pending
-
1993
- 1993-10-08 DK DK112793A patent/DK112793A/da not_active Application Discontinuation
- 1993-10-11 SE SE9303323A patent/SE9303323L/ not_active Application Discontinuation
- 1993-10-16 DE DE4335366A patent/DE4335366A1/de not_active Withdrawn
- 1993-10-20 FR FR9312505A patent/FR2697163B1/fr not_active Expired - Fee Related
- 1993-10-22 GB GB9321794A patent/GB2272697A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JPH06192296A (ja) | 1994-07-12 |
| GB2272697A (en) | 1994-05-25 |
| GB9321794D0 (en) | 1993-12-15 |
| DE4335366A1 (de) | 1994-05-05 |
| DK112793D0 (da) | 1993-10-08 |
| FR2697163B1 (fr) | 1995-06-23 |
| SE9303323D0 (sv) | 1993-10-11 |
| FR2697163A1 (fr) | 1994-04-29 |
| DK112793A (da) | 1994-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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