SE9401965D0 - New compounds - Google Patents

New compounds

Info

Publication number
SE9401965D0
SE9401965D0 SE9401965A SE9401965A SE9401965D0 SE 9401965 D0 SE9401965 D0 SE 9401965D0 SE 9401965 A SE9401965 A SE 9401965A SE 9401965 A SE9401965 A SE 9401965A SE 9401965 D0 SE9401965 D0 SE 9401965D0
Authority
SE
Sweden
Prior art keywords
pct
lower alkyl
compounds
proviso
sec
Prior art date
Application number
SE9401965A
Other languages
English (en)
Swedish (sv)
Inventor
Bernard Robin Boar
Duncan Alastair Gray
Dennis Mark O'shea
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9401965A priority Critical patent/SE9401965D0/xx
Publication of SE9401965D0 publication Critical patent/SE9401965D0/xx
Priority to IL11377395A priority patent/IL113773A/xx
Priority to HR9401965-0A priority patent/HRP950302A2/xx
Priority to ZA954145A priority patent/ZA954145B/xx
Priority to CN95193504A priority patent/CN1051546C/zh
Priority to BR9507923A priority patent/BR9507923A/pt
Priority to US08/448,411 priority patent/US5843971A/en
Priority to EP95922031A priority patent/EP0765325A1/en
Priority to CZ963577A priority patent/CZ357796A3/cs
Priority to AU26859/95A priority patent/AU691303B2/en
Priority to HU9603386A priority patent/HUT76050A/hu
Priority to CA002190128A priority patent/CA2190128A1/en
Priority to PL95318470A priority patent/PL318470A1/xx
Priority to FI964879A priority patent/FI964879A0/fi
Priority to RU97100178/04A priority patent/RU2155763C2/ru
Priority to PCT/SE1995/000604 priority patent/WO1995033747A1/en
Priority to NZ287973A priority patent/NZ287973A/en
Priority to JP8500744A priority patent/JPH10503172A/ja
Priority to EE9600197A priority patent/EE9600197A/xx
Priority to SK1556-96A priority patent/SK155696A3/sk
Priority to MA23913A priority patent/MA23574A1/fr
Priority to TNTNSN95065A priority patent/TNSN95065A1/fr
Priority to US08/485,719 priority patent/US5665747A/en
Priority to YU38695A priority patent/YU38695A/sh
Priority to DZ950069A priority patent/DZ1895A1/fr
Priority to IS4383A priority patent/IS4383A/is
Priority to NO965182A priority patent/NO307421B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE9401965A 1994-06-07 1994-06-07 New compounds SE9401965D0 (sv)

Priority Applications (27)

Application Number Priority Date Filing Date Title
SE9401965A SE9401965D0 (sv) 1994-06-07 1994-06-07 New compounds
IL11377395A IL113773A (en) 1994-06-07 1995-05-18 1,1-bis (heteroazolyl) alkane derivatives and neuroprotective pharmaceutical compositions comprising them
HR9401965-0A HRP950302A2 (en) 1994-06-07 1995-05-22 Novel 1,1-bis(heteroazolyl)alkane derivatives and their use as neuroprotective agents
ZA954145A ZA954145B (en) 1994-06-07 1995-05-22 Novel 1,1-bis(heteroazolyl) alkane derivatives and their use as neuroprotective agents
SK1556-96A SK155696A3 (en) 1994-06-07 1995-05-29 Novel 1,1-bis(heteroazolyl)alkane derivatives and their use as neuroprotective agents
PL95318470A PL318470A1 (en) 1994-06-07 1995-05-29 Novel derivatives of 1,1-bis (heteroazolyl) alkanes and their application as neutroprotective factors
PCT/SE1995/000604 WO1995033747A1 (en) 1994-06-07 1995-05-29 Novel 1,1-bis(heteroazolyl)alkane derivatives and their use as neuroprotective agents
US08/448,411 US5843971A (en) 1994-06-07 1995-05-29 1, 1-BIS (heteroazolyl) alkane derivatives and their use as neuroprotective agents
EP95922031A EP0765325A1 (en) 1994-06-07 1995-05-29 Novel 1,1-bis(heteroazolyl)alkane derivatives and their use as neuroprotective agents
CZ963577A CZ357796A3 (en) 1994-06-07 1995-05-29 Novel 1,1-bis(heteroazolyl(-alkane derivatives and their use as neuroprotective agents
AU26859/95A AU691303B2 (en) 1994-06-07 1995-05-29 Novel 1,1-bis(heteroazolyl)alkane derivatives and their use as neuroprotective agents
HU9603386A HUT76050A (en) 1994-06-07 1995-05-29 1,1-bis(heteroazolyl)alkane derivatives, process for their preparation, pharmaceutical compositions containing them and their use as neuroprotective agents
CA002190128A CA2190128A1 (en) 1994-06-07 1995-05-29 Novel 1,1-bis(heteroazolyl)alkane derivatives and their use as neuroprotective agents
CN95193504A CN1051546C (zh) 1994-06-07 1995-05-29 新的1,1-双杂唑基烷烃衍生物及其作为神经保护剂的用途
FI964879A FI964879A0 (fi) 1994-06-07 1995-05-29 Uusia, 1,1-bis(heteroazolyyli)alkaanijohdoksia ja niiden käyttö hermostoa suojelevina aineina
RU97100178/04A RU2155763C2 (ru) 1994-06-07 1995-05-29 Производные 1,1-бис(гетероазолил)алканов, способ их получения, фармацевтическая композиция и способ лечения с использованием этих соединений
BR9507923A BR9507923A (pt) 1994-06-07 1995-05-29 Composto processo para sus preparação formulação farmacêutica aplicação do composto e processo para o tratamento de distúrbios neuropsiquiátricos agudos e crônicos
NZ287973A NZ287973A (en) 1994-06-07 1995-05-29 1,1-bis(heteroazolyl)alkane derivatives and medicaments used to treat neuropsychiatric disorders
JP8500744A JPH10503172A (ja) 1994-06-07 1995-05-29 新しい１，１−ビス（ヘテロアゾリル）アルカン誘導体および神経保護剤としてのその使用
EE9600197A EE9600197A (et) 1994-06-07 1995-05-29 Uudsed 1,1-bis(heteroasolüül)alkaani derivaadid ja nende kasutamine neuroprotektiivsete ainetena
MA23913A MA23574A1 (fr) 1994-06-07 1995-06-01 Nouveaux derives alcanes 1,1-bis (heteroazolyl) et leur utilisation comme agents neuro-inhibiteurs
TNTNSN95065A TNSN95065A1 (fr) 1994-06-07 1995-06-06 Nouveaux derives alcanes 1,1-bis (heteroazolyl) et leur utilisation comme agents neuro-inhibiteurs
US08/485,719 US5665747A (en) 1994-06-07 1995-06-07 1,1-bis(heteroazolyl)alkane derivatives and their use as neuroprotective agents
YU38695A YU38695A (sh) 1994-06-07 1995-06-07 Novi derivati 1,1-bis(heteroazolil)alkana postupci njihovog dobijanja i farmaceutski preparati koji sadrže ova jedinjenja kao sredstva za neurološku zaštitu
DZ950069A DZ1895A1 (fr) 1994-06-07 1995-07-03 Nouveaux dérivés alcanes 1,1-bis (hétéroazolyl) etleur utilisation comme agents neuro-inhibiteurs.
IS4383A IS4383A (is) 1994-06-07 1996-11-12 Ný 1,1-bis(heteróasólýl)alkanafleiður og notkun þeirra sem taugaverndandi efna
NO965182A NO307421B1 (no) 1994-06-07 1996-12-04 Nye 1,1-bis(heteroazolyl)alkanderivater, farmasøytisk preparat inneholdende slike derivater, deres anvendelse, samt mellomprodukter

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9401965A SE9401965D0 (sv) 1994-06-07 1994-06-07 New compounds

Publications (1)

Publication Number Publication Date
SE9401965D0 true SE9401965D0 (sv) 1994-06-07

Family

ID=20394274

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9401965A SE9401965D0 (sv) 1994-06-07 1994-06-07 New compounds

Country Status (26)

Country Link
US (2) US5843971A (cs)
EP (1) EP0765325A1 (cs)
JP (1) JPH10503172A (cs)
CN (1) CN1051546C (cs)
AU (1) AU691303B2 (cs)
BR (1) BR9507923A (cs)
CA (1) CA2190128A1 (cs)
CZ (1) CZ357796A3 (cs)
DZ (1) DZ1895A1 (cs)
EE (1) EE9600197A (cs)
FI (1) FI964879A0 (cs)
HR (1) HRP950302A2 (cs)
HU (1) HUT76050A (cs)
IL (1) IL113773A (cs)
IS (1) IS4383A (cs)
MA (1) MA23574A1 (cs)
NO (1) NO307421B1 (cs)
NZ (1) NZ287973A (cs)
PL (1) PL318470A1 (cs)
RU (1) RU2155763C2 (cs)
SE (1) SE9401965D0 (cs)
SK (1) SK155696A3 (cs)
TN (1) TNSN95065A1 (cs)
WO (1) WO1995033747A1 (cs)
YU (1) YU38695A (cs)
ZA (1) ZA954145B (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9401965D0 (sv) * 1994-06-07 1994-06-07 Astra Ab New compounds
US6921538B2 (en) * 2002-05-10 2005-07-26 Allergan, Inc. Therapeutic treatments for neuropsychiatric disorders
US7649098B2 (en) * 2006-02-24 2010-01-19 Lexicon Pharmaceuticals, Inc. Imidazole-based compounds, compositions comprising them and methods of their use
TW200920355A (en) * 2007-09-06 2009-05-16 Lexicon Pharmaceuticals Inc Compositions and methods for treating immunological and inflammatory diseases and disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2801794A1 (de) * 1978-01-17 1979-07-19 Basf Ag Verfahren zur herstellung von thiazolderivaten und neue thiazole
US5554620A (en) * 1993-09-14 1996-09-10 Sterling Winthrop Inc. Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof
SE9401965D0 (sv) * 1994-06-07 1994-06-07 Astra Ab New compounds

Also Published As

Publication number Publication date
CN1051546C (zh) 2000-04-19
AU2685995A (en) 1996-01-04
US5843971A (en) 1998-12-01
TNSN95065A1 (fr) 1996-02-06
DZ1895A1 (fr) 2002-02-17
CZ357796A3 (en) 1997-06-11
WO1995033747A1 (en) 1995-12-14
MA23574A1 (fr) 1995-12-31
EE9600197A (et) 1997-06-16
AU691303B2 (en) 1998-05-14
HRP950302A2 (en) 1997-08-31
RU2155763C2 (ru) 2000-09-10
JPH10503172A (ja) 1998-03-24
EP0765325A1 (en) 1997-04-02
IS4383A (is) 1996-11-12
FI964879A7 (fi) 1996-12-05
FI964879L (fi) 1996-12-05
HUT76050A (en) 1997-06-30
ZA954145B (en) 1995-12-07
BR9507923A (pt) 1997-09-23
YU38695A (sh) 1998-12-23
PL318470A1 (en) 1997-06-23
IL113773A (en) 2000-02-29
NO965182L (no) 1996-12-04
CA2190128A1 (en) 1995-12-14
NZ287973A (en) 1998-04-27
FI964879A0 (fi) 1996-12-05
IL113773A0 (en) 1995-08-31
SK155696A3 (en) 1997-05-07
NO307421B1 (no) 2000-04-03
NO965182D0 (no) 1996-12-04
CN1150426A (zh) 1997-05-21
US5665747A (en) 1997-09-09
HU9603386D0 (en) 1997-01-28

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