SE9904108D0 - Nya föreningar - Google Patents

Nya föreningar

Info

Publication number
SE9904108D0
SE9904108D0 SE9904108A SE9904108A SE9904108D0 SE 9904108 D0 SE9904108 D0 SE 9904108D0 SE 9904108 A SE9904108 A SE 9904108A SE 9904108 A SE9904108 A SE 9904108A SE 9904108 D0 SE9904108 D0 SE 9904108D0
Authority
SE
Sweden
Prior art keywords
sub
new compounds
treatment
antibacterial
antiparasitic
Prior art date
Application number
SE9904108A
Other languages
English (en)
Swedish (sv)
Inventor
Sabrina Muzi
Shoa A Abdul-Rahman
Original Assignee
New Pharma Research Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New Pharma Research Ab filed Critical New Pharma Research Ab
Priority to SE9904108A priority Critical patent/SE9904108D0/xx
Publication of SE9904108D0 publication Critical patent/SE9904108D0/xx
Priority to EP00980176A priority patent/EP1230235B1/de
Priority to AT00980176T priority patent/ATE398117T1/de
Priority to US10/111,898 priority patent/US6967205B1/en
Priority to PCT/SE2000/002217 priority patent/WO2001036408A1/en
Priority to JP2001538897A priority patent/JP2003514812A/ja
Priority to AU17472/01A priority patent/AU1747201A/en
Priority to DE60039183T priority patent/DE60039183D1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Quinoline Compounds (AREA)
  • Fodder In General (AREA)
SE9904108A 1999-11-15 1999-11-15 Nya föreningar SE9904108D0 (sv)

Priority Applications (8)

Application Number Priority Date Filing Date Title
SE9904108A SE9904108D0 (sv) 1999-11-15 1999-11-15 Nya föreningar
EP00980176A EP1230235B1 (de) 1999-11-15 2000-11-13 Verbindungen mit antibakteriellen und antiparasitischen eigenschaften
AT00980176T ATE398117T1 (de) 1999-11-15 2000-11-13 Verbindungen mit antibakteriellen und antiparasitischen eigenschaften
US10/111,898 US6967205B1 (en) 1999-11-15 2000-11-13 Compounds with antibacterial and antiparasitic properties
PCT/SE2000/002217 WO2001036408A1 (en) 1999-11-15 2000-11-13 Compounds with antibacterial and antiparasitic properties
JP2001538897A JP2003514812A (ja) 1999-11-15 2000-11-13 抗菌性および抗寄生虫性を有する化合物
AU17472/01A AU1747201A (en) 1999-11-15 2000-11-13 Compounds with antibacterial and antiparasitic properties
DE60039183T DE60039183D1 (de) 1999-11-15 2000-11-13 Verbindungen mit antibakteriellen und antiparasitischen eigenschaften

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9904108A SE9904108D0 (sv) 1999-11-15 1999-11-15 Nya föreningar

Publications (1)

Publication Number Publication Date
SE9904108D0 true SE9904108D0 (sv) 1999-11-15

Family

ID=20417705

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9904108A SE9904108D0 (sv) 1999-11-15 1999-11-15 Nya föreningar

Country Status (8)

Country Link
US (1) US6967205B1 (de)
EP (1) EP1230235B1 (de)
JP (1) JP2003514812A (de)
AT (1) ATE398117T1 (de)
AU (1) AU1747201A (de)
DE (1) DE60039183D1 (de)
SE (1) SE9904108D0 (de)
WO (1) WO2001036408A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8163769B2 (en) 2002-03-12 2012-04-24 Abbott Laboratories Antibacterial compounds
GB0215775D0 (en) * 2002-07-06 2002-08-14 Astex Technology Ltd Pharmaceutical compounds
CN1688193A (zh) * 2002-10-11 2005-10-26 明治制果株式会社 用于防治寄生虫的混合组合物
CA2518443A1 (en) * 2003-03-12 2004-09-30 Abbott Laboratories Naphthyridine derivatives as antibacterial agents
WO2005026147A1 (ja) 2003-09-10 2005-03-24 Kyorin Pharmaceutical Co., Ltd. ７−（４−置換−３−シクロプロピルアミノメチル−１−ピロリジニル）キノロンカルボン酸誘導体
US20050124625A1 (en) * 2003-10-21 2005-06-09 Salvati Mark E. Piperazine derivatives and their use as modulators of nuclear hormone receptor function
US7498341B2 (en) * 2004-01-31 2009-03-03 Sanofi Aventis Deutschland Gmbh Heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments
CA2561621A1 (en) * 2004-03-31 2005-10-20 Bayer Pharmaceuticals Corporation Quinolone carboxylic acid derivatives for treatment of hyperproliferative conditions
US7825122B2 (en) 2005-12-14 2010-11-02 Amgen Inc. Diaza heterocyclic sulfonamide derivatives and their uses
CA2645376C (en) * 2006-03-13 2017-06-20 Activx Biosciences, Inc. Aminoquinolones as gsk-3 inhibitors
JP5322927B2 (ja) * 2007-05-24 2013-10-23 杏林製薬株式会社 １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体
US7902227B2 (en) 2007-07-27 2011-03-08 Janssen Pharmaceutica Nv. C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
CN102351880B (zh) * 2007-09-11 2014-11-12 杏林制药株式会社 作为gsk-3 抑制剂的氰基氨基喹诺酮和四唑并氨基喹诺酮
US8476261B2 (en) 2007-09-12 2013-07-02 Kyorin Pharmaceutical Co., Ltd. Spirocyclic aminoquinolones as GSK-3 inhibitors
WO2009090548A2 (en) * 2008-01-17 2009-07-23 Glenmark Pharmaceuticals, S.A. 3-azabicyclo [3.1.0] hexane derivatives as vanilloid receptor ligands
FR2928150A1 (fr) * 2008-02-29 2009-09-04 Vetoquinol Sa Sa Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens
MX2011009414A (es) 2009-03-11 2011-10-19 Kyorin Seiyaku Kk 7-cicloalquiloaminoquinolonas como inhibidores de gsk-3.
CN102030737B (zh) * 2010-10-29 2014-03-26 重庆巴仕迪动物药业有限公司 克林沙星氨基衍生物及其应用
WO2013142628A2 (en) * 2012-03-20 2013-09-26 Fred Hutchinson Cancer Research Center Antibiotic compounds and compositions, and methods for identification thereof
AU2013296289B2 (en) * 2012-08-03 2017-10-05 Gilead Sciences, Inc. Process and intermediates for preparing integrase inhibitors
CN107406390B (zh) * 2014-11-17 2021-04-16 奈吉治疗公司 单羧酸转运蛋白调节剂及其用途
CN108349968A (zh) * 2015-07-28 2018-07-31 维奥梅生物科学私人有限公司 抗菌治疗剂和预防剂
DE102017218119A1 (de) * 2017-10-11 2019-04-11 Christian-Albrechts-Universität Zu Kiel In der Umwelt abbaubare Chinolon-Antibiotika mit Hemiaminal-Struktureinheit
CN108484577B (zh) * 2018-03-05 2021-03-30 复旦大学 一种嘧啶-喹诺酮类杂合物及其制备方法和用途
CN111087409B (zh) * 2018-10-24 2021-06-08 江阴安博生物医药有限公司 一种喹诺酮类化合物及其制备方法和应用
US20220064159A1 (en) * 2018-12-18 2022-03-03 Elanco Tiergesundheit Ag Bicyclic derivatives
CN109942546B (zh) * 2019-04-16 2022-04-08 西南大学 喹诺酮嘧啶类化合物及其制备方法和应用

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5466686A (en) * 1977-09-20 1979-05-29 Dainippon Pharmaceut Co Ltd Quinoline-3-carboxylic acid derivative, its preparation, and pharmaceutical composition containig the same
GB1598915A (en) * 1977-09-20 1981-09-23 Bellon Labor Sa Roger 1,4-dihydro-quinoline-3-carboxylic acid derivatives process for their preparation and composition containing them
JPS5630964A (en) * 1979-08-22 1981-03-28 Kyorin Pharmaceut Co Ltd Novel substituted quinolinecarboxylic acid and its preparation
GB2093018B (en) * 1979-08-22 1984-09-12 Kyorin Seiyaku Kk 6,8-difluoro-quinoline carboxylic acid derivatives
JPS5746986A (en) * 1980-09-02 1982-03-17 Dai Ichi Seiyaku Co Ltd Pyrido(1,2,3-de)(1,4)benzoxazine derivative
DE3033157A1 (de) * 1980-09-03 1982-04-01 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3142854A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3308909A1 (de) * 1983-03-12 1984-09-13 Bayer Ag, 5090 Leverkusen Bakterizide mittel auf chinoloncarbonsaeure-basis
NZ208470A (en) * 1983-07-18 1988-06-30 Abbott Lab 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such
AU553415B2 (en) 1983-09-19 1986-07-17 Abbott Japan Co., Ltd. 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids
JPS60190777A (ja) * 1984-03-12 1985-09-28 Hokuriku Seiyaku Co Ltd 光学活性な６，８−ジフルオロ−１，４−ジヒドロ−４−オキソ−７−置換ピペラジニルキノリン−３−カルボン酸誘導体
EP0154780B1 (de) 1984-01-26 1990-04-11 Abbott Laboratories Antibakterielle Chinolinderivate
IT1173374B (it) * 1984-02-24 1987-06-24 Mediolanum Farmaceutici Srl Derivati pirido-benzotiazinici ad elevata attivita' antimicrobica
DE3608745A1 (de) * 1985-07-24 1987-01-29 Bayer Ag Bakterizide zubereitungen zur anwendung auf dem gebiet der veterinaermedizin
DE3632222A1 (de) * 1986-09-23 1988-04-07 Bayer Ag Topisch anwendbare zubereitungen von gyrase-inhibitoren
DE3637649A1 (de) * 1986-10-13 1988-04-14 Uwe Dr Spohr Verwendung von 4-chinolon-derivaten zur bekaempfung von protozoen und helminthen
DE3639465A1 (de) * 1986-11-18 1988-05-19 Hoechst Ag Optisch aktive gyrasehemmer, ihre herstellung und verwendung als antibiotika
MY104139A (en) * 1988-08-09 1994-02-28 Daiichi Seiyaku Co Antimicrobial agent for animals
US5225413A (en) * 1988-09-16 1993-07-06 Bayer-Aktiengesellschaft pH-neutral aqueous solutions of quinolone-carboxylic acids
US5164402A (en) 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids
US5266569A (en) * 1989-08-16 1993-11-30 Pfizer Inc. Azatricyclo carboxylic acids useful as anti-bacterial agents
FR2674854B1 (fr) * 1991-04-04 1995-03-03 Bouchara Nouvelles quinolones leur procede de preparation et les compositions pharmaceutiques en refermant.
IT1251202B (it) * 1991-09-13 1995-05-04 Mediolanum Farmaceutici Spa 6-amminochinoloni, sintesi ed impiego come antibatterici
US5395936A (en) * 1993-06-04 1995-03-07 Manzo; Ruben H. 7-(4-[4-aminophenyl)sulphonyl]-1-piperazinyl fluorquinolonic derivatives and synthesis
EP0676199B1 (de) * 1994-04-07 1998-09-02 Pfizer Inc. Verwendung von Trovafloxacin oder dessen Derivaten zur Herstellung eines Arzneimittels zur Behandlung von H.Pylori Infektionen
DE19519822A1 (de) * 1995-05-31 1996-12-05 Bayer Ag Neue antibakterielle Mittel

Also Published As

Publication number Publication date
US6967205B1 (en) 2005-11-22
DE60039183D1 (de) 2008-07-24
ATE398117T1 (de) 2008-07-15
EP1230235B1 (de) 2008-06-11
WO2001036408A1 (en) 2001-05-25
AU1747201A (en) 2001-05-30
EP1230235A1 (de) 2002-08-14
JP2003514812A (ja) 2003-04-22

Similar Documents

Publication Publication Date Title
SE9904108D0 (sv) Nya föreningar
BR0200782A (pt) Compostos para o tratamento da isquemia
EG25017A (en) N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones as antimicrobials.
BR0307432A (pt) Difluormetiltiazolilcarboxanilidas
DE60214591D1 (en) Pyrazolpyrimidinfungizide
WO2002101073A3 (en) Aryl-benzimidazole compounds having antiinfective activity
ATE354622T1 (de) Flüssigkristallines medium
SE0203070D0 (en) Novel compounds
TR200201128T2 (tr) PDE4 inhibitörleri olarak tetrahidrotiyopiranfitalazinon türevleri.
TR200302288T2 (tr) Terapi için yeni bileşikler ve metotlar.
ES2169242T3 (es) 2-amino-benzoxazinonas para el tratamiento de infecciones virales.
DE50310579D1 (de) Furancarboxamide
BR0316086A (pt) N-sulfonil-4-metileno amino-3-hidróxi-2-piridonas como agente microbicida
DK1204659T3 (da) Serotonerge benzofuraner
ATE437866T1 (de) Mikrobizide oxathiincarboxamide
ATE223226T1 (de) Azazyklohexapeptid-verbindungen
DE60005517D1 (de) Kaliumkanal-blockierende mittel
GB0103240D0 (en) Organic compounds
PT1244614E (pt) Inibidores de triptase
WO2004094370A3 (en) Antibacterial pyrazole carboxylic acid hydrazides
DE50303586D1 (de) Methylthiophencarboxanilide
ATE491709T1 (de) Pyrrolidinohydrochinazoline
DE69706950D1 (de) Furoindolizine
PT1104419E (pt) Derivados de azabicicloheptano substituidos no azoto sua preparacao e utilizacao
PT1140932E (pt) Derivados de 1,8-benzonaftiridina