|
US5279960A
(en)
*
|
1984-07-05 |
1994-01-18 |
Enzon Corp. |
25 KD coccidial antigen of eimeria tenella
|
|
US4732974A
(en)
*
|
1986-03-05 |
1988-03-22 |
Mallinckrodt, Inc. |
Metal ion labeling of carrier molecules
|
|
US5047513A
(en)
*
|
1986-07-10 |
1991-09-10 |
Hoffmann-La Roche Inc. |
Metal chelate resins
|
|
CA1340522C
(en)
*
|
1987-03-10 |
1999-05-04 |
Heinz Dobeli |
Fusion proteins containing neighbouring histidines for improved purification
|
|
GB8706599D0
(en)
*
|
1987-03-19 |
1987-04-23 |
Hoffmann La Roche |
Plasmodium falciparum merozoite antigen peptides
|
|
US5780038A
(en)
*
|
1987-11-16 |
1998-07-14 |
Roche Diagnostic Systems, Inc. |
HIV-2 envelope polypeptides
|
|
EP0316695B1
(de)
*
|
1987-11-16 |
1993-03-31 |
F. Hoffmann-La Roche Ag |
Rekombinante HIV-2 Polypeptide
|
|
JPH084519B2
(ja)
*
|
1987-12-25 |
1996-01-24 |
エフ・ホフマン―ラ ロシュ アーゲー |
ハイブリッド形成用担体およびその調整方法
|
|
US4927879A
(en)
*
|
1988-02-25 |
1990-05-22 |
Purdue Research Foundation |
Method for solid phase membrane mimetics
|
|
US4931498A
(en)
*
|
1988-02-25 |
1990-06-05 |
Purdue Research Foundation |
Immobilized artificial membranes
|
|
US4952321A
(en)
*
|
1988-10-07 |
1990-08-28 |
Brigham Young University |
Process of removing and concentrating desired ions from solutions
|
|
US5169936A
(en)
*
|
1989-04-14 |
1992-12-08 |
Biogen, Inc. |
Protein purification on immobilized metal affinity resins effected by elution using a weak ligand
|
|
US5115102A
(en)
*
|
1989-07-21 |
1992-05-19 |
Monsanto Company |
Variant proteins and polypeptides possessing enhanced affinity for immobilized-metal affinity matrices
|
|
US6683046B1
(en)
*
|
1989-12-22 |
2004-01-27 |
Hoffmann-La Roche Inc. |
Purification and characterization of cytotoxic lymphocyte maturation factor and monoclonal antibodies thereto
|
|
US5182369A
(en)
*
|
1990-02-28 |
1993-01-26 |
Monsanto Company |
Method for purifying somatotropin monomers
|
|
US5136025A
(en)
*
|
1990-04-04 |
1992-08-04 |
California Biotechnology Inc. |
Method to purify basic fibroblast growth factor
|
|
EP0527778B1
(en)
*
|
1990-04-09 |
1996-06-19 |
The Upjohn Company |
Improved process of purifying recombinant proteins and compounds useful in such process
|
|
US5594115A
(en)
*
|
1990-04-09 |
1997-01-14 |
Pharmacia & Upjohn Company |
Process of purifying recombinant proteins and compounds useful in such process
|
|
US5972337A
(en)
*
|
1990-11-01 |
1999-10-26 |
Cancer Research Fund Of Contra Costa |
46 kilodalton human milk fat globule (HMFG) antigen, fragments and fusion protein
|
|
HUT69963A
(en)
*
|
1990-12-13 |
1995-09-28 |
Upjohn Co |
Non-naturally-occuring fusion proteins and process for preparing them
|
|
AU1332992A
(en)
*
|
1991-01-25 |
1992-08-27 |
Sloan-Kettering Institute For Cancer Research |
Antigen recognized by patients with antibody associated cerebellar degeneration, dna encoding same and uses thereof
|
|
US5439829A
(en)
*
|
1991-01-30 |
1995-08-08 |
Eli Lilly And Company |
Immobilization of biologically active molecules by changing the Oxidation state of a chelated transition metal ion
|
|
CA2063316A1
(en)
*
|
1991-03-19 |
1992-09-20 |
Larry C. Blaszczak |
Dna and amino acid sequence of penicillin binding protein 2a from staphylococcus aureus strain 27r and derivatives for use in purification thereof and assay for compounds effective against methicillin resistant organisms
|
|
US6602861B1
(en)
|
1992-04-16 |
2003-08-05 |
Research Corporation Technologies, Inc. |
Acylated phospholipid drugs
|
|
EP0583894A3
(en)
*
|
1992-07-29 |
1995-09-06 |
Hybritech Inc |
Method of immobilizing and orienting molecules by use of metal chelating moieties to facilitate atomic force microscopy of proteins and molecular scale manipulation
|
|
US7105159B1
(en)
*
|
1992-11-05 |
2006-09-12 |
Sloan-Kettering Institute For Cancer Research |
Antibodies to prostate-specific membrane antigen
|
|
US7070782B1
(en)
*
|
1992-11-05 |
2006-07-04 |
Sloan-Kettering Institute For Cancer Research |
Prostate-specific membrane antigen
|
|
US6569432B1
(en)
*
|
1995-02-24 |
2003-05-27 |
Sloan-Kettering Institute For Cancer Research |
Prostate-specific membrane antigen and uses thereof
|
|
SE9303822D0
(sv)
*
|
1993-11-18 |
1993-11-18 |
Kabi Pharmacia Ab |
Method for purification
|
|
US5449758A
(en)
*
|
1993-12-02 |
1995-09-12 |
Life Technologies, Inc. |
Protein size marker ladder
|
|
DE4433980C2
(de)
*
|
1994-09-23 |
1996-08-22 |
Boehringer Ingelheim Int |
Verfahren und Biosensorhit zur Untersuchung der Wechselwirkung von Biomolekülen mittels Oberflächen-Plasma-Resonanz
|
|
US5837520A
(en)
*
|
1995-03-07 |
1998-11-17 |
Canji, Inc. |
Method of purification of viral vectors
|
|
US5753206A
(en)
*
|
1995-06-07 |
1998-05-19 |
Immunomedics, Inc. |
Radiometal-binding analogues of luteinizing hormone releasing hormone
|
|
US20040253246A1
(en)
*
|
1996-02-23 |
2004-12-16 |
Israeli Ron S. |
Prostate-specific membrane antigen and uses thereof
|
|
ES2108652B1
(es)
*
|
1996-04-19 |
1998-07-16 |
Antibioticos Sa |
Un procedimiento para modificar la enzima 7/3-(4-carboxibutanamido) cefalosporinacilasa y purificarla en un solo paso cromatografico.
|
|
DE59711533D1
(de)
|
1996-07-26 |
2004-05-27 |
Aventis Pharma Gmbh |
Insulinderivate mit erhöhter Zinkbindung
|
|
US6261823B1
(en)
|
1996-12-13 |
2001-07-17 |
Schering Corporation |
Methods for purifying viruses
|
|
US6544769B1
(en)
*
|
1996-12-13 |
2003-04-08 |
Schering Corporation |
Compostions comprising viruses and methods for concentrating virus preparations
|
|
US6271000B1
(en)
*
|
1996-12-13 |
2001-08-07 |
Eli Lilly And Company |
Streptococcus pneumoniae gene sequence mraY
|
|
US20080261289A1
(en)
*
|
1996-12-13 |
2008-10-23 |
Schering-Plough Corporation |
Compositions comprising viruses and methods for concentrating virus preparations
|
|
EP2336313A1
(en)
|
1997-01-08 |
2011-06-22 |
Life Technologies Corporation |
Methods for production of proteins
|
|
US5932102A
(en)
*
|
1998-01-12 |
1999-08-03 |
Schering Corporation |
Immobilized metal, affinity chromatography
|
|
US7026456B1
(en)
*
|
1998-01-23 |
2006-04-11 |
Hoffman-La Roche, Inc. |
Antibodies against human IL-12
|
|
US6008329A
(en)
*
|
1998-03-06 |
1999-12-28 |
The United States Of America As Represented By The Secretary Of The Army |
Method for purifying cholera toxin
|
|
AU4187799A
(en)
*
|
1998-05-14 |
1999-11-29 |
Clontech Laboratories, Inc. |
Compositions and methods for protein purification based on metal ion affinity site
|
|
DE19825447A1
(de)
*
|
1998-06-06 |
1999-12-09 |
Hoechst Marion Roussel De Gmbh |
Neue Insulinanaloga mit erhöhter Zinkbildung
|
|
US7176298B2
(en)
|
1998-09-25 |
2007-02-13 |
Clontech Laboratories, Inc. |
Polynucleotides encoding metal ion affinity peptides and related products
|
|
US6475743B1
(en)
|
1998-10-02 |
2002-11-05 |
Ischemia Technologies, Inc. |
Marker useful for detection and measurement of free radical damage and method
|
|
US7449338B2
(en)
*
|
1998-10-02 |
2008-11-11 |
Ischemia Technologies, Inc. |
Tests for the rapid evaluation of ischemic states and kits
|
|
US20030215359A1
(en)
*
|
1998-10-02 |
2003-11-20 |
Ischemia Technologies, Inc. |
Tests for the rapid evaluation of ischemic states and kits
|
|
US7070937B1
(en)
|
1998-10-02 |
2006-07-04 |
Ischemia Technologies, Inc. |
Marker useful for detection and measurement of free radical damage and method
|
|
US20050142613A1
(en)
*
|
1998-10-02 |
2005-06-30 |
David Bar-Or |
Test for the rapid evaluation of ischemic states and kits
|
|
US7282369B2
(en)
*
|
1998-10-02 |
2007-10-16 |
Ischemia Technologies, Inc. |
Tests for the rapid evaluation of ischemic states and kits
|
|
US6479300B1
(en)
|
1999-03-15 |
2002-11-12 |
Millipore Corporation |
Metal loaded ligand bound membranes for metal ion affinity chromatography
|
|
US6379903B1
(en)
|
1999-10-08 |
2002-04-30 |
Sigma-Aldrich Co. |
Purification of recombinant proteins fused to multiple epitopes
|
|
CA2386626A1
(en)
*
|
1999-10-15 |
2001-04-26 |
Richard Murphy |
Targeted vectors
|
|
US6521111B1
(en)
|
2000-04-10 |
2003-02-18 |
Invitrogen Corporation |
Methods and articles for labeling polymer gels
|
|
US6623655B1
(en)
|
2000-04-24 |
2003-09-23 |
Sigma-Aldrich Co. |
Metal chelating compositions
|
|
DE50112379D1
(de)
*
|
2000-08-11 |
2007-05-31 |
Univ Ruprecht Karls Heidelberg |
Fv-konstrukte mit beeinflussbarer affinitat zu einer zu bindenden substanz
|
|
DE10040179A1
(de)
*
|
2000-08-17 |
2002-02-28 |
Ipk Inst Fuer Pflanzengenetik |
Beeinflussung der Verteilung von Metallen in transgenen Pflanzen
|
|
US20040180415A1
(en)
*
|
2001-05-15 |
2004-09-16 |
Tchaga Grigoriy S. |
Methods and compositions for protein purification
|
|
ATE394412T1
(de)
|
2001-06-21 |
2008-05-15 |
Clontech Lab Inc |
Wasserlösliche polymere zusammensetzungen mit affinität für metallionen und verfahren zu deren anwendung
|
|
US6902914B2
(en)
*
|
2001-09-28 |
2005-06-07 |
Sigma-Aldrich, Co. |
Recombinant DNA processes using a dNTP mixture containing modified nucleotides
|
|
US7799561B2
(en)
*
|
2002-06-12 |
2010-09-21 |
Sigma-Aldrich, Co. |
Affinity peptides and method for purification of recombinant proteins
|
|
US8025873B2
(en)
*
|
2002-06-20 |
2011-09-27 |
Paladin Labs, Inc. |
Chimeric antigens for eliciting an immune response
|
|
US8029803B2
(en)
|
2002-06-20 |
2011-10-04 |
Paladin Labs, Inc. |
Chimeric antigens for eliciting an immune response
|
|
BR0316560A
(pt)
*
|
2002-11-26 |
2005-10-04 |
Nobex Corp |
Conjugado de composto natriurético, formulação farmacêutica, método de tratar uma condição, método de preparação do conjugado de composto natriurético, conjugado de peptìdeo pró-polinatriurético modificado, análogo de peptìdeo natriurético, análogo de hbnp, composto, e, método de preparar um composto
|
|
ITMI20030755A1
(it)
*
|
2003-04-11 |
2004-10-12 |
Bottega Verde S R L |
Peptidi e loro derivati quali inibitori di fenomeni degradativi e composizioni contenenti gli stessi.
|
|
KR20060036901A
(ko)
*
|
2003-05-02 |
2006-05-02 |
시그마-알드리치컴퍼니 |
고상 세포 용해 및 포획 플랫폼
|
|
JP4078247B2
(ja)
*
|
2003-05-02 |
2008-04-23 |
キヤノン株式会社 |
磁性体−生体物質複合体型構造体、磁性体に対して結合能を有するアミノ酸配列を有するペプチド断片及びその遺伝子、ならびに磁性体−生体物質複合体型構造体の製造方法
|
|
US20040224425A1
(en)
*
|
2003-05-08 |
2004-11-11 |
Gjerde Douglas T. |
Biomolecule open channel solid phase extraction systems and methods
|
|
US8007805B2
(en)
*
|
2003-08-08 |
2011-08-30 |
Paladin Labs, Inc. |
Chimeric antigens for breaking host tolerance to foreign antigens
|
|
US7187286B2
(en)
|
2004-03-19 |
2007-03-06 |
Applera Corporation |
Methods and systems for using RFID in biological field
|
|
WO2006026248A1
(en)
|
2004-08-25 |
2006-03-09 |
Sigma-Aldrich Co. |
Compositions and methods employing zwitterionic detergent combinations
|
|
US7294614B2
(en)
*
|
2004-10-12 |
2007-11-13 |
Clontech Laboratories, Inc. |
Phosphoprotein affinity resins and methods for making and using the same
|
|
JP2008520616A
(ja)
*
|
2004-11-24 |
2008-06-19 |
アプラーゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング |
固相ペプチド合成および精製方法
|
|
KR20070100307A
(ko)
|
2004-12-22 |
2007-10-10 |
제넨테크, 인크. |
가용성 다중 막관통 단백질의 생산 방법
|
|
WO2006076471A2
(en)
*
|
2005-01-12 |
2006-07-20 |
Nobex Corporation |
Bnp conjugates and methods of use
|
|
JP2006239661A
(ja)
*
|
2005-03-07 |
2006-09-14 |
Pentax Corp |
吸着剤、吸着剤の製造方法、吸着装置および吸着装置の製造方法
|
|
US7229769B2
(en)
*
|
2005-03-25 |
2007-06-12 |
Illumina, Inc. |
Compositions and methods for detecting protease activity
|
|
US7741053B2
(en)
*
|
2005-05-13 |
2010-06-22 |
Sigma-Aldrich Co. |
Processes for purification of recombinant proteins
|
|
US7265213B2
(en)
*
|
2005-07-28 |
2007-09-04 |
Kpl, Inc. |
Methodology of conjugating chelators to biomolecules
|
|
JP2009511024A
(ja)
*
|
2005-10-13 |
2009-03-19 |
ヴィレックス メディカル コーポレイション |
免疫応答を誘導するためのC型肝炎ウイルスポリペプチドおよびFcフラグメントを含むキメラ抗原
|
|
JP2009525749A
(ja)
*
|
2006-02-08 |
2009-07-16 |
ユーエスヴィー リミテッド |
組換えタンパク質の精製のためのアフィニティーポリペプチド
|
|
GB0604187D0
(en)
*
|
2006-03-02 |
2006-04-12 |
Fusion Antibodies Ltd |
Peptide and uses thereof
|
|
WO2007120999A2
(en)
*
|
2006-03-06 |
2007-10-25 |
Bio-Rad Laboratories, Inc. |
Chelating monomers and polymers
|
|
EP1878739A1
(en)
*
|
2006-07-14 |
2008-01-16 |
LEK Pharmaceuticals D.D. |
One step IMAC (MCAC) purification of proteins
|
|
WO2009093962A1
(en)
*
|
2008-01-24 |
2009-07-30 |
Ge Healthcare Bio-Sciences Ab |
Multifunctional tags
|
|
CA2727803C
(en)
|
2008-05-13 |
2013-03-12 |
University Of Kansas |
Metal abstraction peptide (map) tag and associated methods
|
|
KR101790187B1
(ko)
|
2009-07-24 |
2017-10-25 |
이뮨 디자인 코포레이션 |
신드비스 바이러스 외피 당단백질로 가성형태화된 렌티바이러스 벡터
|
|
US20120263754A1
(en)
|
2011-02-15 |
2012-10-18 |
Immune Design Corp. |
Methods for Enhancing Immunogen Specific Immune Responses by Vectored Vaccines
|
|
AU2012243039B2
(en)
|
2011-04-08 |
2017-07-13 |
Immune Design Corp. |
Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses
|
|
WO2013067448A2
(en)
|
2011-11-03 |
2013-05-10 |
Vca Antech Inc. |
Compositions and methods to detect various infectious organisms
|
|
DK2831095T3
(en)
|
2012-03-30 |
2019-02-18 |
Immune Design Corp |
LENTIVIRAL VECTOR PARTICLES WITH IMPROVED TRANSDUCTION EFFICIENCY FOR CELL EXPRESSING DC SIGN
|
|
HU230585B1
(hu)
|
2012-05-30 |
2017-01-30 |
Budapesti Műszaki és Gazdaságtudományi Egyetem |
Fehérjék megkötésére és elválasztására alkalmas lantanida fémionokkal komplexált hordozók
|
|
WO2013181461A2
(en)
|
2012-06-01 |
2013-12-05 |
University Of Kansas |
Metal abstraction peptide with superoxide dismutase activity
|
|
WO2015123496A1
(en)
|
2014-02-14 |
2015-08-20 |
Immune Design Corp. |
Immunotherapy of cancer through combination of local and systemic immune stimulation
|
|
KR20170032373A
(ko)
|
2014-07-15 |
2017-03-22 |
이뮨 디자인 코포레이션 |
Tlr4 작용제 보조제 및 렌티바이러스 벡터를 이용한 프라임-부스트 요법
|
|
CA3004132A1
(en)
|
2015-11-09 |
2017-05-18 |
Immune Design Corp. |
A retroviral vector for the administration and expression of replicon rna expressing heterologous nucleic acids
|
|
SG11201803546WA
(en)
|
2015-11-09 |
2018-05-30 |
Immune Design Corp |
Compositions comprising lentiviral vectors expressing il-12 and methods of use thereof
|
|
EP3746222A1
(en)
|
2018-01-30 |
2020-12-09 |
Life Technologies Corporation |
Instruments, devices and consumables for use in a workflow of a smart molecular analysis system
|
|
JP7691701B2
(ja)
|
2019-06-18 |
2025-06-12 |
マックス-プランク-ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ |
金属錯体試薬を介するHisタグ付タンパク質などの標的分子への標識および/または担体の部位特異的、速度論的に不活性なコンジュゲーション
|
|
EP4090674A4
(en)
|
2020-01-14 |
2024-01-24 |
Synthekine, Inc. |
Biased il2 muteins methods and compositions
|
|
JP2023511274A
(ja)
|
2020-01-14 |
2023-03-17 |
シンセカイン インコーポレイテッド |
Il2オルソログおよび使用法
|
|
EP4192880A4
(en)
|
2020-08-05 |
2025-04-30 |
Synthekine, Inc. |
IL10 receptor-binding molecules and methods of use
|
|
CN116323669A
(zh)
|
2020-08-05 |
2023-06-23 |
辛德凯因股份有限公司 |
受体配对相关的组合物和方法
|
|
US12234291B2
(en)
|
2020-08-05 |
2025-02-25 |
Synthekine, Inc. |
IL2RB binding molecules and methods of use
|
|
WO2022031870A1
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
IL27Rα BINDING MOLECULES AND METHODS OF USE
|
|
WO2022031885A2
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il10ra binding molecules and methods of use
|
|
JP7819178B2
(ja)
|
2020-08-05 |
2026-02-24 |
シンセカイン インコーポレイテッド |
IL10Rb結合分子および使用方法
|
|
BR112023001723A2
(pt)
|
2020-08-05 |
2023-05-02 |
Synthekine Inc |
Moléculas de ligação à gp130 e métodos de uso
|
|
US12077594B2
(en)
|
2020-08-05 |
2024-09-03 |
Synthekine, Inc. |
IL2RG binding molecules and methods of use
|
|
EP4192877A4
(en)
|
2020-08-05 |
2024-10-16 |
Synthekine, Inc. |
SYNTHETIC IL2RB/IL2RG CYTOKINES
|
|
CA3204162A1
(en)
|
2021-01-11 |
2022-07-14 |
Robert Kastelein |
Compositions and methods related to receptor pairing
|
|
EP4370139A4
(en)
|
2021-07-14 |
2025-10-15 |
Synthekine Inc |
METHODS AND COMPOSITIONS FOR USE IN CELL THERAPY FOR NEOPLASTIC DISEASE
|
|
WO2024086739A1
(en)
|
2022-10-20 |
2024-04-25 |
Synthekine, Inc. |
Methods and compositions of il12 muteins and il2 muteins
|